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See detailDevelopment and in vitro characterisation of novel bioresorbable and bioactive composite materials based on polylactide foams and Bioglass (R) for tissue engineering applications
Roether, J. A.; Boccaccini, Aldo R.; Hench, L. L. et al

in Biomaterials (2002), 23(18), 3871-3878

Bioactive and bioresorbable composite materials were fabricated using macroporous poly(DL-lactide) (PDLLA) foams coated with and impregnated by bioactive glass (Bioglass®) particles. Stable and ... [more ▼]

Bioactive and bioresorbable composite materials were fabricated using macroporous poly(DL-lactide) (PDLLA) foams coated with and impregnated by bioactive glass (Bioglass®) particles. Stable and homogeneous Bioglasss coatings on the surface of PDLLA foams as well as infiltration of Bioglass® particles throughout the porous network were achieved using a slurry-dipping technique in conjunction with pre-treatment of the foams in ethanol. The quality of the bioactive glass coatings was reproducible in terms of thickness and microstructure. Additionally, electrophoretic deposition was investigated as an alternative method for the fabrication of PDLLA foam/Bioglass® composite materials. In vitro studies in simulated body fluid (SBF) were performed to study the formation of hydroxyapatite (HA) on the surface of PDLLA/Bioglass® composites. SEM analysis showed that the HA layer thickness rapidly increased with increasing time in SBF. The high bioactivity of the PDLLA foam/Bioglasss composites indicates the potential of the materials for use as bioactive, resorbable scaffolds in bone tissue engineering. [less ▲]

Detailed reference viewed: 113 (3 ULiège)
See detailDevelopment and integration of entomopathogenic fungi for crops protection in Democratic Republic of Congo
Fingu Mabola, Junior Corneille ULiege; Bawin, Thomas; Nsevolo Miankeba, Papy et al

Poster (2017)

The Democratic Republic of the Congo (DR Congo) has enormous agricultural potentialities likely to contribute to its economic development. However, the sector is characterized by significant yield losses ... [more ▼]

The Democratic Republic of the Congo (DR Congo) has enormous agricultural potentialities likely to contribute to its economic development. However, the sector is characterized by significant yield losses due notably to the pressure of pests. In response to this situation, most farmers use synthetic chemical pesticides, despite the problems of residues on harvested materials and their widely documented side effects on biodiversity. Up to now, efforts are made to promote healthy farming in the long term, taking into account both economic and environmental aspects. According to this principals, pest management is now achieved through the combination of agronomic, biological and physical means, chemical control being the last resort if necessary. Considering the context of DR Congo, biological control remains by far the least developed of all means in pest management. This is due to the lack of technical equipment. Nevertheless, compared to entomophagous macroorganisms, microorganisms offer the advantage of not requiring substantial resources for their integration into agriculture. This is notably the case for entomopathogenic fungi (EF): in addition to the fact that they may be multiplied on readily available substrates, their abundance in nature makes it possible to isolate new, more efficient strains with more or less marked selectivity. However, very little research on EF is carried out in this country. The present study aims to integrate these biological control agents into the pest management strategy in DR Congo. This research project will focus on two approaches: (1) evaluation of the genetic diversity of EF strains in DR Congo, which will lead to the establishment of a reference collection; and (2) screening of potential candidates for biopesticide development. Researches will be carried out on the southwestern part of the country, focusing on insect cadavers and soil samples from cultivated areas. Pure strains will be isolated on synthetic culture media then identified according to their morphological, physiological and molecular traits. Biological tests including virulence and effectiveness under various environmental conditions in laboratory will be carried out against the most important agricultural pests to be determined following a field monitoring. Finally, culture trials of EF with locally available resources at low cost will be conducted to encourage the adoption of the technology. [less ▲]

Detailed reference viewed: 100 (2 ULiège)
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See detailDevelopment and Layout of a ACC-System by means of Evolutionary Algorithms
Christen, Fréderic ULiege

Scientific conference (2007, August 22)

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See detailDevelopment and numerical validation of a 2-scale computational model to study the mechanical behavior of nanocrystalline metals
Péron, Vincent ULiege

Doctoral thesis (2014)

This work aims at predicting the mechanical behavior of nanocrystalline structure using a 2-scale approach. Molecular simulations using the quasicontinuum method (QC) are performed to obtain the ... [more ▼]

This work aims at predicting the mechanical behavior of nanocrystalline structure using a 2-scale approach. Molecular simulations using the quasicontinuum method (QC) are performed to obtain the mechanical responses of the grain-boundaries and grains at the nanoscale. A finite element model is then calibrated using these atomistic results. This 2-scale model accounts for intergranular and intragranular plasticity, can predict the intergranular failure, and is able to study large structures. [less ▲]

Detailed reference viewed: 153 (30 ULiège)
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See detailDevelopment and optimisation of methods to synthesise sol-gel nanoparticles and sol-gel core-shell nanoparticles to produce nanosensors
De Bleye, Charlotte ULiege

Master's dissertation (2011)

The aim of this project was to synthesise nanosensors. It can be defined as an inert, biofriendly matrix in which sensing molecules are entrapped, allowing determination of analytes concentration. Two ... [more ▼]

The aim of this project was to synthesise nanosensors. It can be defined as an inert, biofriendly matrix in which sensing molecules are entrapped, allowing determination of analytes concentration. Two types of nanosensors were synthesised according to the Stöber method and characterised by a scanning electron microscope and a CPS disc centrifuge. The nanosensors were calibrated with succes using a fluorimeter. [less ▲]

Detailed reference viewed: 63 (20 ULiège)
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See detailDevelopment and optimization of a TD-GC/MS methodology for detection and quantifi cation of furan released in air using of an experimental design.
Alsafra, Zouheir ULiege; Scholl, Georges ULiege; Romain et al

Poster (2016, July 07)

In the aim of understanding the way in which human is exposed to furan present in the air of an occupational area, an analytical method of Thermal desorption-gas chromatography/Mass spectrometry (TD-GC/MS ... [more ▼]

In the aim of understanding the way in which human is exposed to furan present in the air of an occupational area, an analytical method of Thermal desorption-gas chromatography/Mass spectrometry (TD-GC/MS) has been developed and optimized using a Plackett–Burman experimental design. This method was then used to study the phenomena of diffusion of furan released in air from a contamination source. This source of furan is simply a coffee machine located in a closed controlled room. Results show that furan concentration increases quickly over time after turning on the coffee machine until reaching a maxima. Then it starts to decrease slowly. On the other hand, concentration of furan seems to be identical everywhere in the conditioned room in each moment. [less ▲]

Detailed reference viewed: 58 (21 ULiège)
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See detailDevelopment and optimization of pegylated lipoplexes for vaginal application
Lechanteur, Anna ULiege; Furst, Tania ULiege; Kanber, Erdem et al

Conference (2014, October 04)

Detailed reference viewed: 34 (8 ULiège)
Peer Reviewed
See detailDevelopment and organization of executive functions in 4-to 11 year-old children: A factor study.
Catale, Corinne ULiege; Collette, Fabienne ULiege; Lejeune, Caroline ULiege et al

in Books of Abstract: Annual Meeting of the Belgian Association for Psychological Science (2011)

Executive functioning (EF) is an umbrella term used to refer to the higher-order cognitive processes whose principal function is to facilitate the adaptation of an individual to new and non-routine ... [more ▼]

Executive functioning (EF) is an umbrella term used to refer to the higher-order cognitive processes whose principal function is to facilitate the adaptation of an individual to new and non-routine situations. In the present study, inhibition, mental flexibility, and working memory were assessed through 6 executive tasks administered to 329 children aged from 4 to 11 years, in order to examine the development and organization of executive functioning in both early and middle childhood. Results reveal specific developmental trends for each component, with a period of rapid general development during the preschool period. Confirmatory factor analyses were used to examine the organization of EF in our sample. First, the poorness of fit of the unitary model was found for both groups, confirming the fractionated nature of EF in preschoolers as well as in older children. Second, the analyses confirmed the adequacy of the fit of the three-dimensional model (i.e., inhibition, flexibility, and working memory), while also indicating that other specific two-dimensional models gave reasonable fits to the data from both age groups. The factor structure obtained supports both the unitary and diversity nature of the executive organisation during early and middle childhood. Furthermore, our data suggest a progressive differentiation of executive processes (in particular flexibility and working memory) in the course of development. [less ▲]

Detailed reference viewed: 133 (25 ULiège)
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See detailDevelopment and performance assessment of a luminex xMAP(R) direct hybridization assay for the detection and identification of indoor air fungal contamination.
Libert, Xavier; Packeu, Ann; Bureau, Fabrice ULiege et al

in PLoS ONE (2017), 12(3), 0173390

Considered as a public health problem, indoor fungal contamination is generally monitored using classical protocols based on culturing. However, this culture dependency could influence the ... [more ▼]

Considered as a public health problem, indoor fungal contamination is generally monitored using classical protocols based on culturing. However, this culture dependency could influence the representativeness of the fungal population detected in an analyzed sample as this includes the dead and uncultivable fraction. Moreover, culture-based protocols are often time-consuming. In this context, molecular tools are a powerful alternative, especially those allowing multiplexing. In this study a Luminex xMAP(R) assay was developed for the simultaneous detection of 10 fungal species which are most frequently in indoor air and that may cause health problems. This xMAP(R) assay was found to be sensitive, i.e. its limit of detection is ranging between 0.05 and 0.01 ng of gDNA. The assay was subsequently tested with environmental air samples which were also analyzed with a classical protocol. All the species identified with the classical method were also detected with the xMAP(R) assay, however in a shorter time frame. These results demonstrate that the Luminex xMAP(R) fungal assay developed in this study could contribute to the improvement of public health and specifically to the indoor fungal contamination treatment. [less ▲]

Detailed reference viewed: 20 (2 ULiège)
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See detailDevelopment and performance assessment of a qualitative SYBR(R) green real-time PCR assay for the detection of Aspergillus versicolor in indoor air.
Libert, X.; Chasseur, C.; Bladt, S. et al

in Applied Microbiology and Biotechnology (2015), 99(17), 7267-7282

Currently, contamination of indoor environment by fungi and molds is considered as a public health problem. The monitoring of indoor airborne fungal contamination is a common tool to help understanding ... [more ▼]

Currently, contamination of indoor environment by fungi and molds is considered as a public health problem. The monitoring of indoor airborne fungal contamination is a common tool to help understanding the link between fungi in houses and respiratory problems. Classical analytical monitoring methods, based on cultivation and microscopic identification, depend on the growth of the fungi. Consequently, they are biased by difficulties to grow some species on certain culture media and under certain conditions or by noncultivable or dead fungi that can consequently not be identified. However, they could have an impact on human health as they might be allergenic. Since molecular methods do not require a culture step, they seem an excellent alternative for the monitoring of indoor fungal contaminations. As a case study, we developed a SYBR(R) green real-time PCR-based assay for the specific detection and identification of Aspergillus versicolor, which is frequently observed in indoor environment and known to be allergenic. The developed primers amplify a short region of the internal transcribed spacer 1 from the 18S ribosomal DNA complex. Subsequently, the performance of this quantitative polymerase chain reaction (qPCR) method was assessed using specific criteria, including an evaluation of the selectivity, PCR efficiency, dynamic range, and repeatability. The limit of detection was determined to be 1 or 2 copies of genomic DNA of A. versicolor. In order to demonstrate that this SYBR(R) green qPCR assay is a valuable alternative for monitoring indoor fungal contamination with A. versicolor, environmental samples collected in contaminated houses were analyzed and the results were compared to the ones obtained with the traditional methods. [less ▲]

Detailed reference viewed: 12 (4 ULiège)
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See detailDevelopment and performance assessment of an improved 8-node mixed type FEM element
Duchene, Laurent ULiege; de Montleau, P.; Habraken, Anne ULiege

in Juster, Neal; Rosochowski, Andrzej (Eds.) Proceedings of the 9th International ESAFORM Conference on Material Forming (2006)

Several finite element (FE) simulations were investigated using a recently developed mixed type element: the BWD3D. The main formulation of the element is largely described, with particular focus on the ... [more ▼]

Several finite element (FE) simulations were investigated using a recently developed mixed type element: the BWD3D. The main formulation of the element is largely described, with particular focus on the shear locking treatment. The formulation of the former BLZ3D element is also presented for comparison. The examples investigated in the present study were beam bending, large strain torsion, incremental forming and deep drawing .The numerical results obtained with both elements were compared to experiments. [less ▲]

Detailed reference viewed: 55 (13 ULiège)
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See detailDevelopment and Pilot Trial Results of Stochastic Targeted (STAR) Glycemic Control in a Medical ICU
Fisk, Liam M.; Le Compte, Aaron J.; Shaw, Geoffrey M. et al

in Proceedings of the 8th IFAC Symposium on Biological and Medical Systems (2012, August)

Detailed reference viewed: 21 (2 ULiège)
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See detailDevelopment and pre-validation of a high sensitive method for the determination of levonorgestrel in human plasma by SPE/LC/MS-MS
Hubert, Cédric ULiege; streel, Bruno; Sibenaler, Renilde et al

Poster (2007, July)

Detailed reference viewed: 33 (4 ULiège)