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See detailDifferentiating between influencing factors land use and climate to assess drought effects on groundwater recharge in a temperate context
Verbeiren, Boud; Huysmans, Marijke; Vanderhaegen, Sven et al

Conference (2014, November)

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See detailDifferentiating muscle damage from myocardial injury by meaans of the serum creatinine kinase (CK) isoenzyme MB mass measurement/total CK activity ratio
el Allaf, M.; Chapelle, Jean-Paul ULg; El Allaf, Dia ULg et al

in Clinical Chemistry (1986), 32(2), 291-5

We immunoenzymometrically measured creatine kinase (CK) isoenzyme MB in extracts of myocardium and in homogenates of five different skeletal muscles. CK-MB concentrations in the former averaged 80.9 ... [more ▼]

We immunoenzymometrically measured creatine kinase (CK) isoenzyme MB in extracts of myocardium and in homogenates of five different skeletal muscles. CK-MB concentrations in the former averaged 80.9 micrograms/g wet tissue; in the skeletal muscles it varied widely, being (e.g.) 25-fold greater in diaphragm than in psoas. CK-MB in skeletal muscles ranged from 0.9 to 44 ng/U of total CK; the mean for myocardium was 202 ng/U. In sera from 10 trauma and 36 burn patients without myocardial involvement, maximum ratios for CK-MB mass/total CK activity averaged 7 (SEM 1) ng/U and 18 (SEM 6) ng/U, respectively. Except for an infant (220 ng/U), the highest ratio we found for serum after muscular damage was 38 ng/U. In contrast, the mean maximum ratio determined in 23 cases of acute myocardial infarction exceeded 200 ng/U. Among seven determinations performed 8 to 32 h after onset of symptoms, each infarct patient demonstrated at least one ratio greater than or equal to 110 ng/U. Ratios observed after infarct were unrelated to treatment received during the acute phase. We propose a CK-MB/total CK ratio of 80 ng/U as the cutoff value for differentiating myocardial necrosis from muscular injury. [less ▲]

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See detailDifferentiation Ability and Oncogenic Potential of Hpv-33- and Hpv-33 + Ras-Transfected Keratinocytes
Gilles, Christine ULg; Piette, Jacques ULg; Peter, W. et al

in International Journal of Cancer = Journal International du Cancer (1994), 58(6), 847-54

Five HPV-33-immortalized and 5 HPV-33 + ras-transfected cell lines were characterized in terms of growth in soft agar, tumorigenic potential in nude mice, p21 expression, morphology and expression of ... [more ▼]

Five HPV-33-immortalized and 5 HPV-33 + ras-transfected cell lines were characterized in terms of growth in soft agar, tumorigenic potential in nude mice, p21 expression, morphology and expression of differentiation markers in organotypic cultures. No striking differences were observed between the HPV-33-immortalized cell lines and their corresponding ras-transfected counterparts as regards their tumorigenicity in nude mice (only one cell line was able to develop tumors in nude mice) or their behavior on lifted collagen gels. However, all the ras-transfected cell lines gave rise to colonies in soft agar while only 2 HPV-33-transfected lines (CK1 and CK4) displayed this property. The 10 cell lines could be divided into 2 groups with respect to their phenotype in monolayer and in organotypic cultures. Lines from group I (CK2, 3, 5 and their ras-transfected homologous lines) shared a typical epithelial phenotype in monolayer and the ability (a) to form an epithelium similar to a CIN-III lesion and (b) to strongly express keratins K1-K10 and involucrin in organotypic cultures. On the other hand, for the lines from group II (CK1, CK4, CK1EJ7 and CK4EJ5), there was a correlation between an elongated phenotype in monolayer and the property (a) to form a structure similar to a microinvasive carcinoma and (b) to express vimentin and keratins K8-K18. These cell lines, exhibiting various transformation-associated alterations, can be considered as an in vitro model representing various stages of HPV-33-associated cervical carcinogenesis. [less ▲]

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See detailDifferentiation Among Potyviruses Infecting Sweet Potato Based on Genus- and Virus-Specific Reverse Transcription Polymerase Chain Reaction
Colinet, Dominique; Nguyen, Minh ULg; Kummert, Jean et al

in Plant Disease (1998), 82(fevrier), 223-229

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See detailDifferentiation between begnin and malignant breast lesions with MR imaging and scintimammography
Servais, Fabienne; Blocklet, Didier; Seret, Alain ULg et al

in Radiology (1997), 205(1), 283

No abstract for this letter.

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See detailDifferentiation between stoichiometric and anticatalytic antioxidant properties of benzoic acid analogues: A structure/redox potential relationship study.
Franck, Thierry ULg; Mouithys-Mickalad, Ange ULg; Robert, Thierry ULg et al

in Chemico-biological interactions (2013), 206(2), 194-203

We investigated the antioxidant activities of some phenolic acid derivatives on a cell free system and on cellular and enzymatic models involved in inflammation. The stoichiometric antioxidant activities ... [more ▼]

We investigated the antioxidant activities of some phenolic acid derivatives on a cell free system and on cellular and enzymatic models involved in inflammation. The stoichiometric antioxidant activities of phenolic acid derivatives were studied by measuring their capacity to scavenge the radical cation 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS+) and reactive oxygen species (ROS) produced by stimulated neutrophils. The anticatalytic antioxidant capacity of the molecules was evaluated on the activity of myeloperoxidase (MPO), an oxidant enzyme present in and released by the primary granules of neutrophils. The ROS produced by PMA-stimulated neutrophils were measured by lucigenin-enhanced chemiluminescence (CL) and the potential interaction of the molecules with MPO was investigated without interferences due to medium by Specific Immuno-Extraction Followed by Enzyme Detection (SIEFED). The antioxidant activities of the phenolic compounds were correlated to their redox potentials measured by differential pulse voltammetry (DPV), and discussed in relation to their molecular structure. The ability of the phenolic molecules to scavenge ABTS radicals and ROS derived from neutrophils was inversely correlated to their increased redox potential. The number of hydroxyl groups (three) and their position (catechol) were essential for their efficacy as stoichiometric antioxidants or scavengers. On MPO activity, the inhibitory capacity of the molecules was not really correlated with their redox potential. Likewise, for the inhibition of MPO activity the number of OH groups and mainly the elongation of the carboxylic group were essential, probably by facilitating the interaction with the active site or the structure of the enzyme. The redox potential measurement, combined with ABTS and CL techniques, seems to be a good technique to select stoichiometric antioxidants but not anticatalytic ones, as seen for MPO, what rather involves a direct interaction with the enzyme. [less ▲]

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See detailDifferentiation in putative male sex pheromone components across and within populations of the African butterfly Bicyclus anynana as a potential driver of reproductive isolation
Bacquet, P.M.B.; De Jong, M.A.; Brattström, O. et al

in Ecology and Evolution (2016), 6

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See detailDifferentiation of Bifidobacterium species by PCR-RFLP
Delcenserie, Véronique ULg; china, bernard; Daube, Georges ULg

Poster (2001)

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See detailDifferentiation of Boettcher's cells during postnatal development of rat cochlea
Cloes, Marie ULg; Renson, Thomas; Johnen, Nicolas ULg et al

Poster (2013)

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See detailDifferentiation of Boettcher's Cells During Postnatal Development of Rat Cochlea
Cloes, Marie ULg; Renson, Thomas; Johnen, Nicolas ULg et al

Poster (2013, January 28)

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See detailDifferentiation of Boettcher’s Cells during Postnatal Development of Rat Cochlea
Cloes, Marie; Renson, Thomas; Johnen, Nicolas et al

Poster (2013, January 28)

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See detailDifferentiation of Boettcher's cells during postnatal development of rat cochlea.
Cloes, Marie ULg; Renson, Thomas; Johnen, Nicolas et al

in Cell and tissue research (2013), 354(3), 707716

Contrary to the highly specialized epithelial cells of the mammalian auditory organ, little is known about the surrounding cells and, in particular, Boettcher's cells (BC). Our morphological studies show ... [more ▼]

Contrary to the highly specialized epithelial cells of the mammalian auditory organ, little is known about the surrounding cells and, in particular, Boettcher's cells (BC). Our morphological studies show that, in rats, these cells began their differentiation around postnatal day 8 (P8) reaching maturity around P20, when they are completely covered by Hensen's and Claudius' cells. Tight junctions were noted near the apex of BC, providing that they were in direct contact with the endolymphatic space, between approximately P8 and P16. We observed gap junctions between BC and adjacent cells before the end of the covering process suggesting the additional involvement of BC in potassium recycling into the endolymph. Adherens junctions were also seen between BC throughout their maturation. Importantly, we noticed cytoplasmic secretory granules and an accumulated material, probably a secretion, in the intercellular space, between P8 and P25. These results indicate that BC could basally take part in the secretion of the extracellular matrix of the basilar membrane. Finally, we show that the basolateral interdigitations of BC are longer and more tighlty grouped at maturity and harbour urea transporters as early as P18. Our observations thus support the view that BC perform several functions. [less ▲]

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See detailDifferentiation of glycans in equine guttural pouches.
Parillo, F.; Rossi, G.; Busoni, Valeria ULg et al

in Veterinary Journal (2008)

The aim of this study was to investigate the carbohydrate composition of mucosubstances in the equine guttural pouches using conventional histochemical tests in conjunction with glycolytic digestion to ... [more ▼]

The aim of this study was to investigate the carbohydrate composition of mucosubstances in the equine guttural pouches using conventional histochemical tests in conjunction with glycolytic digestion to degrade different classes of glycosoaminoglycans. In the goblet cells, the mucopolysaccharides contained chondroitin sulfate B, heparin, heparan sulfate and sialic acid residues. The acinar cells also expressed these substances (except for heparin), whereas the ductal cells produced chondroitin sulfate B and sialic acid. Neutral sugars were also found in each cell type. The diversity of the glycocomponents found in the auditory tube suggests that they may have important functional roles. Indeed, the glycosoaminoglycans provide a hydrophilic environment that prevents dehydration and desiccation of the guttural membranes during air passage. Additionally, these glycomolecules may be involved in the pathogenesis of some bacterial disease in horses, such as equine strangles. [less ▲]

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See detailDifferentiation of patented crystalline glucosamine sulfate from other glucosamine preparations will optimize osteoarthritis treatment.
Saengnipanthkul, Sukit; Waikakul, Saranatra; Rojanasthien, Sattaya et al

in International Journal of Rheumatic Diseases (2017)

Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are recommended for the medium- to long-term management of knee osteoarthritis (OA) due to their abilities to control pain, improve function and ... [more ▼]

Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are recommended for the medium- to long-term management of knee osteoarthritis (OA) due to their abilities to control pain, improve function and delay joint structural changes. Among SYSADOAs, evidence is greatest for the patented crystalline glucosamine sulfate (pCGS) formulation (Mylan). Glucosamine is widely available as glucosamine sulfate (GS) and glucosamine hydrochloride (GH) preparations that vary substantially in molecular form, pharmaceutical formulation and dose regimen. Only pCGS is given as a highly bioavailable once-daily dose (1500 mg), which consistently delivers the plasma levels of around 10 mumol/L required to inhibit interleukin-1-induced expression of genes involved in the pathophysiology of joint inflammation and tissue destruction. Careful consideration of the evidence base reveals that only pCGS reliably provides a moderate effect size on pain that is higher than paracetamol and equivalent to non-steroidal anti-inflammatory drugs (NSAIDs), while non-crystalline GS and GH fail to reach statistical significance for pain reduction. Chronic administration of pCGS has disease-modifying effects, with a reduction in need for total joint replacement lasting for 5 years after treatment cessation. Pharmacoeconomic studies of pCGS demonstrate long-term reduction in additional pain analgesia and NSAIDs, with a 50% reduction in costs of other OA medication and healthcare consultations. Consequently, pCGS is the logical choice, with demonstrated medium-term control of pain and lasting impact on disease progression. Physician and patient education on the differentiation of pCGS from other glucosamine formulations will help to improve treatment selection, increase treatment adherence, and optimize clinical benefit in OA. [less ▲]

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See detailDifferentiation of polymorphs by Ionoluminescence
Calvo Del Castillo, Helena ULg; Chene, Grégoire ULg; Dupuis, Thomas ULg et al

in Physics Procedia (2009), 2

Polymorph minerals are natural materials that share the same composition but have a different structure. Traditionally, the characterization of polymorphs has been done using different techniques of ... [more ▼]

Polymorph minerals are natural materials that share the same composition but have a different structure. Traditionally, the characterization of polymorphs has been done using different techniques of microscopy, X-ray diffraction Raman or IR Spectroscopy for instance. In this work we propose the use of a new technique as an alternative to characterise polymorphs: Ion Beam Induced Luminescence (IBIL). As an advantage to the other techniques, IBIL can be carried out simultaneously with the PIXE technique or other Ion Beam Analysis techniques and the combination will yield results on elemental composition and luminescence properties at the same time. Different minerals have been analysed with IBIL as an example of application to the characterization of polymorphs and its correspondent spectra are explained in this paper. [less ▲]

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See detailDifferentiation of swidden agriculture in Northeast Cambodia: Kavet swiddeners, the state and the markets in Kok Lak commune
You, Rithy; Kleinpeter, Vivien; Diepart, Jean-Christophe ULg

in Diepart, Jean-Christophe (Ed.) Learning for resilience: Insights from Cambodia’s rural communities (2015)

Until recently, Kavet ethnic minority people traditionally practiced swidden agriculture and accessed natural resources in the uplands as an important, and unchallenged, part of their food system. This ... [more ▼]

Until recently, Kavet ethnic minority people traditionally practiced swidden agriculture and accessed natural resources in the uplands as an important, and unchallenged, part of their food system. This present study aims to trace the historical transformation of land use and tenure practices by Kavet communities in Kok Lak commune in the context of various state-driven and social-economic transformations. At commune level, we look at land use changes along with the migrations associated with these transformations. We also aim to understand how these changes have induced social differentiation between households as it relates to their entitlements, their production activities and their income structure. We examine the transformation in land use prompted by a multiplicity of drivers (demographic, economic, political, institutional and cultural) and in land tenure regimes through a land control matrix that differentiates between two types of rights (the land rights of the users and the rights to manage those rights given to the users). We discovered that the Kavet people have been resilient in protecting and promoting the core of their swidden territories and traditions; however, recent developments (including the establishment of the Virachey National Park (VNP) and market incentives) have considerably fragmented their land uses, cultural values and institutions. Through forced and free migration, some households have adopted new forms of agriculture (e.g. paddy, and annual and perennial non-rice crops) and converted their swidden land into cashew plantations, while others still rely solely on the practice of swidden agriculture as a lifestyle. By reviewing past transformations, by identifying the role swidden agriculture has had and the contribution it has made to the lives of the Kavet people, we recommend that efforts be made to conserve it in recognition of the pivotal role it plays in community development and to adopt better land use planning at local level. But proper consideration should also be given to the Kavet people who do not practice swidden agriculture. [less ▲]

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