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See detailEpistemic Logic
Gochet, Paul ULg; Gribomont, Pascal ULg

in Gabbay, Dov; Woods, John (Eds.) Handbook of the History of Logic, vol. 7 (2006)

Detailed reference viewed: 68 (15 ULg)
See detailEpistémologie de la sociologie. Paradigmes pour le 21e siècle
Jacquemain, Marc ULg; Frère, Bruno ULg

Book published by De boeck (2008)

Comment s’articulent, dans la compréhension du monde social, la démarche « savante » du sociologue et la compréhension « ordinaire » des acteurs ? S’impose-t-il de séparer a priori les deux pour aboutir à ... [more ▼]

Comment s’articulent, dans la compréhension du monde social, la démarche « savante » du sociologue et la compréhension « ordinaire » des acteurs ? S’impose-t-il de séparer a priori les deux pour aboutir à l’objectivité scientifique ou, au contraire, de les construire en continuité et dans un dialogue réciproque ? Le développement considérable des sciences sociales au cours du dernier demi-siècle n’a pas abouti à résoudre cette question de manière univoque. Au contraire, plus les sciences sociales – et la sociologie en particulier – ont scruté avec attention des objets concrets, plus les « postures » se sont diversifiées sur cette question. Adressé prioritairement à des étudiants de deuxième cycle, mais susceptible d’intéresser aussi le public non spécialiste, ce livre introduit de manière rigoureuse mais accessible à cette irréductible pluralité. Il passe en revue quelques-unes des positions sociologiques les plus contemporaines en tentant de relever chez chacune, les promesses et les limites, familiarisant le lecteur avec la nécessaire diffraction du regard qui s’impose pour « saisir » ce qui fait le monde social. [less ▲]

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See detailEpistémologie des sciences sociales - Une introduction
Jacquemain, Marc ULg

Learning material (2014)

Le texte constitue un syllabus à destination des étudiants de master. Il constitue une introduction aux trois grands "moments" de la démarche scientifique que sont l'eplication, la vérification et l ... [more ▼]

Le texte constitue un syllabus à destination des étudiants de master. Il constitue une introduction aux trois grands "moments" de la démarche scientifique que sont l'eplication, la vérification et l'intervention. Il défend l'incontournable pluralisme des paradigmes et modèles dans les sciences sociales et termine en prenant comme illustration la pluralité des explications de l'inégalité des chances scolaires. [less ▲]

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See detailEpistémologie et modèles mathématiques
Bair, Jacques ULg; Henry, Valérie ULg; Justens, Daniel

in Tangente Sup (2008), 43

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See detailL’épistémologie française et le concept de norme : de Canguilhem à Foucault
Bolmain, Thomas ULg

Scientific conference (2009, March 25)

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See detailÉpistémologie sémiotique. La théorie du langage de Louis Hjelmslev
Badir, Sémir ULg

Book published by Honoré Champion (2014)

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See detailEpistolari e carteggi cinquecenteschi : Italia e Spagna a confronto
Moreno, Paola ULg

Scientific conference (2009, October 28)

Detailed reference viewed: 9 (0 ULg)
See detailÉpitaphe latine avec traduction française lue lors de la séance du 2 avril 1715 à l'Académie des inscriptions et médailles
Bauden, Frédéric ULg

in Bauden, Frédéric; Waller, Richard (Eds.) Le Journal d'Antoine Galland (1646-1715). La période parisienne. Volume I (1708-1709) (2011)

Detailed reference viewed: 27 (2 ULg)
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See detailEpitaxial growth of CdTe on Si by Molecular Beam Epitaxy
Samain, Louise ULg; Seldrum, Thomas; Dumont, Jacques et al

in Physicalia Magazine (2008), 30(3), 99-112

Detailed reference viewed: 14 (1 ULg)
See detailEpitaxial Si, SiGe and Ge for high-performance devices
Loo, Roger; Hikavyy, Andriy; Vincent, Benjamin et al

Conference (2010, September 23)

Detailed reference viewed: 78 (5 ULg)
Peer Reviewed
See detailEpithelial and endothelial expression of the green fluorescent protein reporter gene under the control of bovine prion protein (PrP) gene regulatory sequences in transgenic mice.
Lemaire-Vieille, C.; Schulze, T.; Podevin-Dimster, V. et al

in Proceedings of the National Academy of Sciences of the United States of America (2000), 97(10), 5422-7

The expression of the cellular form of the prion protein (PrP(c)) gene is required for prion replication and neuroinvasion in transmissible spongiform encephalopathies. The identification of the cell ... [more ▼]

The expression of the cellular form of the prion protein (PrP(c)) gene is required for prion replication and neuroinvasion in transmissible spongiform encephalopathies. The identification of the cell types expressing PrP(c) is necessary to understanding how the agent replicates and spreads from peripheral sites to the central nervous system. To determine the nature of the cell types expressing PrP(c), a green fluorescent protein reporter gene was expressed in transgenic mice under the control of 6.9 kb of the bovine PrP gene regulatory sequences. It was shown that the bovine PrP gene is expressed as two populations of mRNA differing by alternative splicing of one 115-bp 5' untranslated exon in 17 different bovine tissues. The analysis of transgenic mice showed reporter gene expression in some cells that have been identified as expressing PrP, such as cerebellar Purkinje cells, lymphocytes, and keratinocytes. In addition, expression of green fluorescent protein was observed in the plexus of the enteric nervous system and in a restricted subset of cells not yet clearly identified as expressing PrP: the epithelial cells of the thymic medullary and the endothelial cells of both the mucosal capillaries of the intestine and the renal capillaries. These data provide valuable information on the distribution of PrP(c) at the cellular level and argue for roles of the epithelial and endothelial cells in the spread of infection from the periphery to the brain. Moreover, the transgenic mice described in this paper provide a model that will allow for the study of the transcriptional activity of the PrP gene promoter in response to scrapie infection. [less ▲]

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See detailEpithelial expression of mRNA and protein for IL-6, IL-10 and TNF-alpha in endobronchial biopsies in horses with recurrent airway obstruction.
Riihimäki, Miia; Raine, Amanda; Pourazar, Jamshid et al

in BMC Veterinary Research (2008), 4

BACKGROUND: The aim of this study was to evaluate the contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of cytokines of innate immunity IL-6, IL-10 and ... [more ▼]

BACKGROUND: The aim of this study was to evaluate the contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of cytokines of innate immunity IL-6, IL-10 and TNF-alpha, in horses with Recurrent Airway Obstruction (RAO) during exacerbation and in remission. RESULTS: Despite marked clinical and physiologic alterations between exacerbation and after remission in the RAO horses no differences were detected in either cytokine mRNA or protein levels. Moreover, the expression of investigated cytokines in RAO horses on pasture did not differ from controls.In comparing real-time PCR analysis to results of immunohistochemistry only IL-10 mRNA and protein levels in RAO horses on pasture were significantly correlated (rs = 0.893, p = 0.007). Curiously, in controls examined on pasture the TNF-alpha protein level was positively correlated to IL-10 mRNA expression (rs = 0.967, p = 0.007) and negatively correlated to IL-6 mRNA expression (rs = -0.971, p = 0.001). CONCLUSION: Given the complementary relationship of assessing cytokines directly by immunohistochemistry, or indirectly by PCR to mRNA, the lack of significant changes in either mRNA or protein levels of IL-6, IL-10 or TNF-alpha mRNA in RAO horses in exacerbation suggests that these particular cytokines in bronchial tissue may not play a substantive role in the active inflammation of this disease. To support this contention further studies examining time dependency of expression of IL-6, IL-10 or TNF-alpha are needed, as is expansion of the range of cytokines to include other key regulators of airway inflammation. [less ▲]

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See detailEpithelial ingrowth cells after LASIK/ALTK (automated lamellar therapeutic keratoplasty): are they corneal epithelial stem cells?
Nicolas, Michael; Abouzeid, Hana; DEPREZ, Manuel ULg et al

in British Journal of Ophthalmology (2012), 96(7), 1043-6

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See detailEpithelial metaplasia: an inadequate environment for antitumour immunity?
Delvenne, Philippe ULg; Hubert, Pascale ULg; Jacobs, Nathalie ULg

in Trends in Immunology (2004), 25(4), 169-73

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See detailEpithelial supporting cells can differentiate into outer hair cells and Deiters' cells in the cultured organ of Corti
Malgrange, Brigitte ULg; Thiry, Marc ULg; Van De Water, Thomas R. et al

in Cellular and Molecular Life Sciences : CMLS (2002), 59(10), 1744-1757

The organ of Corti is a complex structure containing a single row of inner hair cells (IHCs) and three rows of outer hair cells (OHCs), supported respectively by one row of inner phalangeal cells and ... [more ▼]

The organ of Corti is a complex structure containing a single row of inner hair cells (IHCs) and three rows of outer hair cells (OHCs), supported respectively by one row of inner phalangeal cells and three rows of Deiters' cells. When fetal rat organ of Corti explants are cultured, supernumerary OHCs and supernumerary Deiters' cells are produced, without any additional cell proliferation. Analysis of semi- and ultrathin sections revealed that supernumerary OHCs are produced at the distal edge of the organ of Corti. Quantitative analysis of cell types present in the organ of Corti demonstrates that when the number of OHCs increases: (i) the total number of cells remains constant; (ii) the number of Deiters' cells increases; (iii) the number of tectal cells decreases and of Hensen's cells decreases. Using specific HC markers, i.e. jagged2 (Jag2) and Math1, we showed that in addition to existing OHCs, supernumerary OHCs, tectal cells and Hensen's cells expressed these markers in embryonic day 19 organ of Corti explants after 5 days in vitro. The results of this study suggest that Hensen's cells retain the capacity to differentiate into either tectal cells, which differentiate into OHCs, or into undertectal cells which differentiate into Deiters' cells. [less ▲]

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See detailEpithelial-mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions.
Ullmann, U.; In'T Veld, P.; Gilles, Christine ULg et al

in Molecular Human Reproduction (2007), 13(1), 21-32

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early ... [more ▼]

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early differentiation process. Long-term feeder-free hESC cultures using matrigel and conditioned medium from mouse and from human origin revealed that the appearance of mesenchymal-like cells was similar regardless of the conditioned medium used. Standard characterization confirmed the preservation of hESC properties, but the feeder-free cultures could not be maintained longer than 37 passages. The early differentiation process was characterized in the short term after switching hESCs cultured on feeders to feeder-free conditions. Transmission electron microscopy showed an epithelium-like structure inside the hESC colonies, whereas the peripheral cells revealed the acquisition of a rather mesenchymal-like phenotype. Immunochemistry analysis showed that cells at the periphery of the colonies had a negative E-cadherin expression and a positive Vimentin expression, suggesting an epithelial–mesenchymal transition (EMT). Nuclear staining of ß-catenin, positive N-cadherin and negative Connexin 43 expression were also found in the mesenchymal-like cell population. After RT–PCR analysis, Slug and Snail, both EMT-related transcription factors, were detected as up-regulated in the mesenchymal-like cell population. Taken together, our data suggest that culturing hESCs in feeder-free conditions enhances an early differentiation process identified as an EMT. [less ▲]

Detailed reference viewed: 32 (1 ULg)