First clinical results of licofelone (ml3000), an inhibitor of COX-1, COX-2 and 5-LOX, for the treatment of osteoarthritisReginster, Jean-Yves ; ; in Annals of the Rheumatic Diseases (2002, June), 61(Suppl.1), Detailed reference viewed: 31 (6 ULg) The first community forests of Gabon : towards sustainable local forest management ?Meunier, Quentin ; ; et alin Nature et Faune (2011), 25(2), 40-45 Forest resources abound in Gabon. Species diversity and quality of trees in the Gabonese forests make it a very lucrative production niche. Even though international forest operators are well established ... [more ▼] Forest resources abound in Gabon. Species diversity and quality of trees in the Gabonese forests make it a very lucrative production niche. Even though international forest operators are well established there and are making profit, the Gabonese rural communities have not yet developed their own operations. In view of their remoteness from decision-making centers, villagers often unlawfully lose, without being aware of it, a great deal of the riches in their villages. Today, the rural socio-economic component is not sufficiently integrated in the management factors of the resource, even though populations that depend on them daily are supposedly the best placed individuals to make wise use of them. In this sense, community forestry helps to promote sustainable use of forest resources at a scale that is at par with the needs of the community, and seeks to guarantee that profits are shared at village level. In Gabon, the process of legalization of community forests is ongoing since 2001. Pilot projects such as DACEFI (Development of Community Alternatives to Illegal Logging) strive to assist communities in securing their community forest. However their legalization is slow in coming, while logging activities in the rural forest estate are increasing, and the quality of the species is deteriorating continually. [less ▲] Detailed reference viewed: 114 (14 ULg) First comparisons of precipitable water vapour estimations using GPS and water vapour radiometers at the Royal Observatory of Belgium; Warnant, René ![]() in GPS Solution (2002), 6(1-2), 11-17 Detailed reference viewed: 8 (4 ULg) The first definite record of a Valanginian ichthyosaur and its implications on the evolution of post-Liassic IchthyosauriaFischer, Valentin ; ; et alin Cretaceous Research (2011), 32(2), 155-163 A complete ichthyosaur rostrum, with 124 associated teeth, was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a ... [more ▼] A complete ichthyosaur rostrum, with 124 associated teeth, was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a late Valanginian age (Neocomites peregrinus Zone, Olcostephanus nicklesi Subzone) for this fossil, which consequently represents the first diagnostic ichthyosaur ever reported from Valanginian strata. This specimen also represents the first occurrence of Aegirosaurus outside the Tithonian (Upper Jurassic) lithographic limestones of Bavaria (southern Germany). Tooth morphology and wear pattern suggest that Aegirosaurus belonged to the “Pierce II/ Generalist” feeding guild, which was hitherto not represented in post-Liassic ichthyosaurs. Most Late Jurassic ichthyosaurs actually crossed the Jurassic-Cretaceous boundary. [less ▲] Detailed reference viewed: 54 (7 ULg) A first detailed study of the colliding wind WR+O binary WR 30aGosset, Eric ; ; Rauw, Grégor et alin Monthly Notices of the Royal Astronomical Society (2001), 327 We present a detailed, extensive investigation of the photometric and spectroscopic behaviour of WR 30a. This star is definitely a binary system with a period around 4.6d. We propose the value P=4.619d ... [more ▼] We present a detailed, extensive investigation of the photometric and spectroscopic behaviour of WR 30a. This star is definitely a binary system with a period around 4.6d. We propose the value P=4.619d (sigma=0.002d). The identification of the components as WO4+O5((f)) indicates a massive evolved binary system; the O5 component is a main-sequence or, more likely, a giant star. The radial velocities of the O star yield a circular orbit with an amplitude K[SUB]O[/SUB]=29.9 (sigma=2.1)kms[SUP]-1[/SUP] and a mass function of 0.013 (sigma=0.003)M[SUB]solar[/SUB]. The spectrum of WR 30a exhibits strong profile variations of the broad emission lines that are phase-locked with the orbital period. We report the detection of the orbital motion of the WO component with K[SUB]WO[/SUB]=189kms[SUP]-1[/SUP], but this should be confirmed by further observations. If correct, it implies a mass ratio M[SUB]WO[/SUB] /M[SUB]O[/SUB]=0.16. The star exhibits sinusoidal light variations of amplitude 0.024mag peak-to-peak with the minimum of light occurring slightly after the conjunction with the O star in front. On the basis of the phase-locked profile variations of the Civ lambda4658 blend in the spectrum of the WO, we conclude that a wind-wind collision phenomenon is present in the system. We discuss some possibilities for the geometry of the interaction region. [less ▲] Detailed reference viewed: 2 (0 ULg) First detection of hydroxyl in the atmosphere of Venus; ; et al in Astronomy and Astrophysics (2008), 483 Context: Airglow emissions, such as previously observed from NO and O2(a-X) (0-0) on Venus, provide insight into the chemical and dynamical processes that control the composition and energy balance in the ... [more ▼] Context: Airglow emissions, such as previously observed from NO and O2(a-X) (0-0) on Venus, provide insight into the chemical and dynamical processes that control the composition and energy balance in the upper atmospheres of planets. The OH airglow emission has been observed previously only in the Earth's atmosphere where it has been used to infer atomic oxygen abundances. The O2(a-X) (0-1) airglow emission also has only been observed in the Earth's atmosphere, and neither laboratory nor theoretical studies have reached a consensus on its transition probability. Aims: We report measurements of night-side airglow emission in the atmosphere of Venus in the OH (2-0), OH (1-0), O2(a-X) (0-1), and O2(a-X) (0-0) bands. This is the first detection of the first three of these airglow emissions on another planet. These observations provide the most direct observational constraints to date on H, OH, and O3, key species in the chemistry of Venus' upper atmosphere. Methods: Airglow emission detected at wavelengths of 1.40-1.49 and 2.6-3.14 mum in limb observations by the Visible and Infrared Thermal Imaging Spectrometer (VIRTIS) on the Venus Express spacecraft is attributed to the OH (2-0) and (1-0) transitions, respectively, and compared to calculations from a photochemical model. Simultaneous limb observations of airglow emission in the O2(a-X) (0-0) and (0-1) bands at 1.27 and 1.58 mum, respectively, were used to derive the ratio of the transition probabilities for these bands. Results: The integrated emission rates for the OH (2-0) and (1-0) bands were measured to be 100 ± 40 and 880±90 kR respectively, both peaking at an altitude of 96 ± 2 km near midnight local time for the considered orbit. The measured ratio of the O2(a-X) (0-0) and (0-1) bands is 78 ± 8. Conclusions: Photochemical model calculations suggest the observed OH emission is produced primarily via the Bates-Nicolet mechanism, as on the Earth. The observed ratio of the intensities of the O2(a-X) (0-0) and (0-1) bands implies the ratio of their transition probabilities is 63±6. [less ▲] Detailed reference viewed: 17 (4 ULg) First detection of phase-dependent colliding wind X-ray emission outside the Milky WayNazé, Yaël ; ; et alin Astrophysical Journal (2007), 658(1, Part 2), 25-28 After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton ... [more ▼] After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton. This research provides the first detection of apparently periodic X-ray emission from hot gas produced by the collision of winds in an evolved massive binary outside the Milky Way. It also provides the first X-ray monitoring of a luminous blue variable only years after its eruption and shows that the dominant source of the X-rays is not associated with the ejecta. After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton. This research provides the first detection of apparently periodic X-ray emission from hot gas produced by the collision of winds in an evolved massive binary outside the Milky Way. It also provides the first X-ray monitoring of a luminous blue variable only years after its eruption and shows that the dominant source of the X-rays is not associated with the ejecta. [less ▲] Detailed reference viewed: 8 (2 ULg) First detection of resistance to QOI fungicides in Mycosphaerella graminicola on winter wheat in Belgium; ; et al in Communications in Agricultural and Applied Biological Sciences (2003, May 06), 68(4b), 519-531 Detailed reference viewed: 23 (0 ULg) First Direct Assay for Intact Human Proinsulin; ; Deberg, Michelle et alin Clinical Chemistry (1998), 44(7), 1514-9 We describe a sensitive two-site sandwich enzyme-linked immunosorbent assay for the measurement of intact human proinsulin in 100 microL of serum or plasma. The assay is based on the use of two monoclonal ... [more ▼] We describe a sensitive two-site sandwich enzyme-linked immunosorbent assay for the measurement of intact human proinsulin in 100 microL of serum or plasma. The assay is based on the use of two monoclonal antibodies specific for epitopes at the C-peptide/insulin A chain junction and at the insulin B chain/C-peptide junction, respectively. Cross-reactivities with insulin, C-peptide, and the four proinsulin conversion intermediates were negligible. The detection limit in buffer was 0.2 pmol/L (3 standard deviations from zero). The working range was 0.2-100 pmol/L. The mean intra- and interassay coefficients of variation were 2.4% and 8.9%, respectively. The mean recovery of added proinsulin was 103%. Dilution curves of 40 serum samples are parallel to the proinsulin calibration curve. Proinsulin concentrations in 20 fasting healthy subjects were all above the limit of detection: median (range), 2.7 pmol/L (1.1-6.9 pmol/L). Six fasting non-insulin-dependent diabetes mellitus and five insulinoma patients had proinsulin concentrations significantly higher than healthy subjects: median (range), 7.7 pmol/L (3.2-18 pmol/L) and 153 pmol/L (98-320 pmol/L), respectively. [less ▲] Detailed reference viewed: 6 (1 ULg) First epidemiological data on pathogenic leptospires isolated on the Azorean islands; ; et al in European Journal of Epidemiology (1997), 13 Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s ... [more ▼] Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s.l. serovars (copenhageni, icterohaemorrhagiae and ballum) which have never been previously investigated there. The house mouse and the black rat were the major Leptospira reservoir showing isolation rates ranging from 0% for both species (in Graciosa) to 88 % and 33 %, respectively (in São Miguel). This study also showed that the majority of the animals with positive kidney cultures exhibited specific agglutinins agaibst the isolated strains of Leptospira. The observed isalation rates in the different islands, with a very interesting island variation in prevalence, suggest that small mammals, serving as sylvatic reservoirs of pathogenic leptospires, may represent an important risk to the health of humans and the livestock, particularly in the islands of Terceira and São Miguel. [less ▲] Detailed reference viewed: 8 (2 ULg) First epidemiological study on exposure to Neospora caninum in different canine populations in the Algiers District (Algeria); ; et al in Parasitology International (2009), 58(4), 444-450 Detailed reference viewed: 8 (4 ULg) First estimates of the contribution of CaCO3 precipitation to the release of CO2 to the atmosphere during young sea ice growth; ; et al in Journal of Geophysical Research. Oceans (2012), 118(1-12), We report measurements of pH, total alkalinity, air-ice CO2 fluxes (chamber method) and CaCO3 content of frost flowers (FF) and thin landfast sea ice. As the temperature decreases, concentration of ... [more ▼] We report measurements of pH, total alkalinity, air-ice CO2 fluxes (chamber method) and CaCO3 content of frost flowers (FF) and thin landfast sea ice. As the temperature decreases, concentration of solutes in the brine skim (BS) increases. Along this gradual concentration process, some salts reach their solubility threshold and start precipitating. The precipitation of ikaite (CaCO3.6H2O) was confirmed in the FF and throughout the ice by Raman spectroscopy and X-ray analysis. The amount of ikaite precipitated was estimated to be 25 µmol kg-1 melted FF, in the FF and is shown to decrease from 19 µmol kg-1 to 15 µmol kg-1 melted ice in the upper part and at the bottom of the ice, respectively. CO2 release due to precipitation of CaCO3 is estimated to be 50 µmol kg-1 melted samples. The dissolved inorganic carbon (DIC) normalized to a salinity of 10 exhibits significant depletion in the upper layer of the ice and in the FF. This DIC loss is estimated to be 2069 µmol kg-1 melted sample and corresponds to a CO2 release from the ice to the atmosphere ranging from 20 to 40 mmol m-2 d-1. This estimate is consistent with flux measurements of air-ice CO2 exchange. Our measurements confirm previous laboratory findings that growing young sea ice acts as a source of CO2 to the atmosphere. CaCO3 precipitation during early ice growth appears to promote the release of CO2 to the atmosphere however its contribution to the overall release by newly formed ice is most likely minor. [less ▲] The first events of protochlorophyll(ide) photoreduction investigated in etiolated leaves by means of the fluorescence excited by short, 610 nm laser flashes at room temperature; ; Franck, Fabrice et alin Photobiochemistry and Photobiophysics (1981), 2 Detailed reference viewed: 16 (3 ULg) First evidence for a resolved structure in the inner Vega systemAbsil, Olivier ![]() Poster (2005, October 01) We report on infrared interferometric observations of Vega obtained in May and June 2005 with the FLUOR instrument installed on the CHARA interferometer. The combination of short and long baselines has ... [more ▼] We report on infrared interferometric observations of Vega obtained in May and June 2005 with the FLUOR instrument installed on the CHARA interferometer. The combination of short and long baselines has allowed us to study the brightness distribution of the stellar photosphere, and to detect a spatial component which is over-resolved at our lowest resolution (~15 milli-arcseconds). This would be attributed to structure much larger than Vega, but within the CHARA/FLUOR field-of-view (about 1 arcsecond in radius, i.e., 8 AU around Vega). The contrast between the resolved flux and the central star is only slightly above the 1% level in K band. This emission could be interpreted as the first direct detection of thermal and/or scattered light emanating from the innermost part of the Vega debris disk, which is thought to be continuously replenished by asteroid collisions and/or comet evaporation. The possibility of a close stellar or sub-stellar companion is also investigated. [less ▲] Detailed reference viewed: 4 (0 ULg) First evidence of deuterotokous parthenogenesis in the tomato leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)Caparros Megido, Rudy ; Haubruge, Eric ; Verheggen, François ![]() in Journal of Pest Science (2012) The tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), originates from South America and is now considered to be one of the most damaging invasive pests of tomatoes in the Mediterranean Basin ... [more ▼] The tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), originates from South America and is now considered to be one of the most damaging invasive pests of tomatoes in the Mediterranean Basin countries of Europe and North Africa. The preventing pest mating control methods include: (1) the use of synthetic pheromones for male attraction and annihilation inside insecticide-containing traps; (2) mating disruption by saturating the atmosphere with sex pheromones which alter the ability of males to locate females; and (3) massive applications of sterile males to alter the overall reproductive success of the pest population. However, all these methods achieve only a poor success rate in controlling T. absoluta populations under greenhouse conditions. Sex pheromone management and sterile insect techniques are both based on an important biological trait: the insect must breed through sexual reproduction. Here, we report for the first time laboratory evidence of deuterotokous parthenogenesis, an asexual reproduction where both males and females are produced from unfertilized eggs. We discuss the consequences for T. absoluta control strategies. [less ▲] Detailed reference viewed: 47 (16 ULg) First evidence of progenesis in Triturus (Amphibia)Denoël, Mathieu ; Poster (1998) Paedomorphosis is defined as the retention of subadult morphology in reproductive adults. Two main processes can produce this heterochronic pattern : neoteny and progenesis, but progenesis has not been ... [more ▼] Paedomorphosis is defined as the retention of subadult morphology in reproductive adults. Two main processes can produce this heterochronic pattern : neoteny and progenesis, but progenesis has not been yet demonstrated in newts. Distinction between them can be obtained from the determination of age at first reproduction using the squelettochronological method. In this study, we sampled more than 300 Triturus alpestris in two populations : one in a French Alpine lake and the other in an Italian pond. Results show that paedomorphs from the Italian pond are mature earlier and at a smaller size than metamorphs (Progenesis) whereas paedomorphic and metamorphic newts from the French population do not differ in size and age (Neoteny). Adaptative significance of Paedomorphosis is discussed in relation to the stability of the aquatic habitat [less ▲] Detailed reference viewed: 14 (0 ULg) First evidence of pulsations in Vega?. Results of today's most extensive spectroscopic search; ; et al in Astronomy and Astrophysics (2012), 537 Context. The impact of rapid rotation on stellar evolution theory remains poorly understood as of today. Vega is a special object in this context as spectroscopic and interferometric studies have shown ... [more ▼] Context. The impact of rapid rotation on stellar evolution theory remains poorly understood as of today. Vega is a special object in this context as spectroscopic and interferometric studies have shown that it is a rapid rotator seen nearly pole one, a rare orientation particularly interesting for seismic studies. In this paper, we present a first systematic search for pulsations in Vega. <BR /> Aims: The goal of the present work is to detect for the first time pulsations in a rapidly rotating star seen nearly pole-on. <BR /> Methods: Vega was monitored in quasi-continuous high-resolution echelle spectroscopy. A total of 4478 spectra were obtained. More precisely in 2008 we obtained 1213 spectra during 19.9 h on 3 nights (26th, 27th and 29th of July 2008) with NARVAL/TBL (at R = 65 000 and R = 75 000), in 2009 we obtained 1293 spectra during 13.7 h on 3 nights (9th-11th of September 2009) with ESPaDOnS/CFHT (at R = 68 000) and in 2010 we gathered again 1972 with NARVAL/TBL during 28.8 h on five nights (July 15th-19th). This data set should represent the most extensive high S/N, high resolution quasi-continuous survey obtained on Vega as of today. Least square deconvolved (LSD) profiles were obtained for each spectrum representing the photospheric absorption profile potentially deformed by the presence of pulsations. In addition, we calculated for each spectrum a telluric line LSD profile subsequently used as radial velocity reference. LSD profile centroids were adjusted and velocity differences (stellar-telluric) determined. These residual velocities were analysed and periodic low amplitude variations, potentially indicative of stellar pulsations, detected. In a subsequent step, the temporal line profile variations during the longest (2010) data set was calculated for each individual velocity bin of 1.8 km s[SUP]-1[/SUP] by computing a 2D (velocity-frequency) Lomb-Scargle periodogram. <BR /> Results: Based on high resolution echelle spectroscopy, we have obtained indications of periodic variations of very small amplitudes within the residual radial velocity curves of Vega. All three data sets revealed the presence of residual periodic variations: 5.32 and 9.19 d[SUP]-1[/SUP] (A ≈ 6 m s[SUP]-1[/SUP]) in 2008, 12.71 and 13.25 d[SUP]-1[/SUP] (A ≈ 8 m s[SUP]-1[/SUP]) in 2009 and 5.42 and 10.82 d[SUP]-1[/SUP] (A ≈ 3-4 m s[SUP]-1[/SUP]) in 2010. However, it is too early to conclude that the variations are due to stellar pulsations, and a confirmation of the detection with a highly stable spectrograph is a necessary next step. <BR /> Conclusions: If pulsations are confirmed, their very small amplitudes show that the star would belong to a category of very "quiet" pulsators. Based on observations obtained at the Bernard Lyot Telescope (TBL, Pic du Midi, France) of the Midi-Pyrénées Observatory, which is operated by the Institut National des Sciences de l'Univers (INSU) of the Centre National de la Recherche Scientifique of France (CNRS), and at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, INSU/CNRS and the University of Hawaii. [less ▲] Detailed reference viewed: 15 (9 ULg) First evidence of the possible implication of the 11-deoxycorticosterone (DOC) in immune activity of Eurasian perch (Perca fluviatilis, L.): Comparison with cortisol; ; et al in Comparative Biochemistry & Physiology Part A : Molecular & Integrative Physiology (2013), 165(2), 149-158 Detailed reference viewed: 2 (0 ULg) First example of an unsymmetrical difunctional monomer polymerizable by two living/controlled methods; ; et al in Macromolecular Rapid Communications (2000), 21(11), 779-784 In this paper the synthesis and (co)polymerizations of 4-(acryloyloxy)-epsilon-caprolactone are reported. This new monomer can be polymerized in a living/controlled way by two different polymerization ... [more ▼] In this paper the synthesis and (co)polymerizations of 4-(acryloyloxy)-epsilon-caprolactone are reported. This new monomer can be polymerized in a living/controlled way by two different polymerization mechanisms: atom transfer radical polymerization (ATRP) and ring-opening polymerization (ROP). ATRP, which was carried out at 90 degrees C using NiBr2(PPh3)(2), leads to new polyacrylates containing pendant caprolactone functionalities with controlled molecular weights and narrow polydispersities (M-w/M(p)similar to 1.1). Alternatively, ROP of this functional epsilon-caprolactone bearing a pendant acrylate functionality leads to new poly(4-(acryloyloxy) caprolactone) as well as random copolymers when epsilon-caprolactone and L,L-lactide are added as comonomers. The (co)polymerizations were carried out using either (Al((OPr)-Pr-i)(3) in toluene at 25 degrees C or Sn(Oct)(2) as a catalyst at 110 degrees C producing (co)polymers with controlled molecular weights and narrow polydispersities (M-w/M(n)similar to 1.2). As a potential application, the introduction of acrylate pendant groups into the polyesters facilitated the preparation of cross-linked biodegradable materials either thermally or by irradiation with ultraviolet light radical curing. [less ▲] Detailed reference viewed: 64 (8 ULg) First example of “click” copper(I) catalyzed azide-alkyne cycloaddition in supercritical carbon dioxide: Application to the functionalization of aliphatic polyestersGrignard, Bruno ; Schmeits, Stephanie ; Riva, Raphaël et alin Green Chemistry (2009), 11 The modification of aliphatic polyesters by the copper(I) catalyzed azide-alkyne cycloaddition (CuAAC) was successfully implemented in supercritical carbon dioxide (scCO2). Due to the remarkable ... [more ▼] The modification of aliphatic polyesters by the copper(I) catalyzed azide-alkyne cycloaddition (CuAAC) was successfully implemented in supercritical carbon dioxide (scCO2). Due to the remarkable properties of scCO2, the CuAAC reaction turned out to be quantitative even though the aliphatic polyesters used in this work were insoluble in scCO2. Interestingly enough, the conditions were mild enough to prevent polymer degradation from occurring and finally, efficient removal of the catalyst (>96%) was achieved by scCO2 extraction. [less ▲] Detailed reference viewed: 89 (29 ULg) |
||