Do utility values and willingness to pay suitably reflect health outcome in hip and knee osteoarthritis? A comparative analysis with the WOMAC index
Ethgen, Olivier ; Tancredi, Annalisa ; Lejeune, Emmanuelle et al
in Journal of Rheumatology (2003), 30(11), 2452-2459
Objective. To establish whether health utility (time trade-off, TTO) and willingness to pay (WTP) values reflect clinical health outcome as evaluated by the Western Ontario McMaster Universities ... [more ▼]
Objective. To establish whether health utility (time trade-off, TTO) and willingness to pay (WTP) values reflect clinical health outcome as evaluated by the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) in hip and knee osteoarthritis (OA). Methods. One hundred twenty-eight patients with OA attending a specialized arthritis clinic were interviewed about their socioeconomic characteristics and administered the TTO technique and the WOMAC. Their WTP for 2 hypothetical anti-osteoarthritic drugs was also investigated: the first drug was said to provide a significant improvement in WOMAC dimensions and the second a complete cure of the disease. WTP was elicited by both discrete-choice and bidding game methods. Results. Answer rates were 89.1% for TTO, 98.4% for discrete-choice WTP for both scenarios, and 89.8% and 85.2% for bidding game WTP in the relief and the cure scenario, respectively. The mean TTO utility value was 0.84 (standard deviation 0.20). In discrete-choice, those accepting the bid had higher monthly income (euro 1536.5 vs euro 1060. 1, p < 0.001, for the relief scenario and euro 1449.3 vs euro 1071.6, p < 0.001, for the cure scenario). With the bidding game format, WTP was positively correlated with income in both scenarios (r = 0.56, r = 0.55, p < 0.001). WTP measures differed equally between education and socioeconomic groups with those in favored groups consistently reporting higher WTP (Kruskal-Wallis tests statistics ranging from p < 0.01 to p < 0.001). Except for stiffness, WOMAC dimensions were correlated in the expected direction with TTO values (r = -0.27, p < 0.01 for pain and r = -0.36, r = -0.34, p < 0.001 for physical function and total score, respectively). Conclusion. Whereas they showed good feasibility, WTP measures poorly reflected clinical condition and were mainly related to economic status and ability to pay. TTO was correlated with the WOMAC dimensions and may be considered closer to clinical situations than WTP. However, concern arises regarding the homogeneity of the study sample in terms of clinical severity, which may have precluded the identification of a relationship between WTP and clinical status. [less ▲]Detailed reference viewed: 56 (9 ULg)
Do verbal and perceptual expertises mediate the verbal overshadowing effect in development ?
Vanootighem, Valentine ; Brédart, Serge ; Dehon, Hedwige
Poster (2013, November 22)Detailed reference viewed: 46 (16 ULg)
Do we have enough pieces of the jigsaw to integrate CO2 fluxes in the Coastal Ocean ?
Borges, Alberto ; Delille, Bruno ; et al
Poster (2004, October)Detailed reference viewed: 6 (0 ULg)
Do we have enough pieces of the jigsaw to integrate CO2 fluxes in the Coastal Ocean ?
Conference (2005)Detailed reference viewed: 7 (3 ULg)
Do we have enough pieces of the jigsaw to integrate CO2 fluxes in the Coastal Ocean ?
in Estuaries (2005), 28(1), 3-27
Annually integrated air-water CO2 flux data in 44 coastal environments were compiled from literature. Data were gathered in 8 major ecosystems (inner estuaries, outer estuaries, whole estuarine systems ... [more ▼]
Annually integrated air-water CO2 flux data in 44 coastal environments were compiled from literature. Data were gathered in 8 major ecosystems (inner estuaries, outer estuaries, whole estuarine systems, mangroves, salt marshes, coral reefs, upwelling systems, and open continental shelves), and up-scaled in the first attempt to integrate air-water CO2 fluxes over the coastal ocean (26 3 106 km2), taking into account its geographical and ecological diversity. Air-water CO2 fluxes were then up-scaled in global ocean (362 3 106 km2) using the present estimates for the coastal ocean and those from Takahashi et al. (2002) for the open ocean (336 3 106 km2). If estuaries and salt marshes are not taken into consideration in the up-scaling, the coastal ocean behaves as a sink for atmospheric CO2 (21.17 mol C m22 yr21) and the uptake of atmospheric CO2 by the global ocean increases by 24% (21.93 versus 21.56 Pg C yr21). The inclusion of the coastal ocean increases the estimates of CO2 uptake by the global ocean by 57% for high latitude areas (20.44 versus 20.28 Pg C yr21) and by 15% for temperate latitude areas (22.36 versus 22.06 Pg C yr21). At subtropical and tropical latitudes, the contribution from the coastal ocean increases the CO2 emission to the atmosphere from the global ocean by 13% (0.87 versus 0.77 Pg C yr21). If estuaries and salt marshes are taken into consideration in the upscaling, the coastal ocean behaves as a source for atmospheric CO2 (0.38 mol C m22 yr21) and the uptake of atmospheric CO2 from the global ocean decreases by 12% (21.44 versus 21.56 Pg C yr21). At high and subtropical and tropical latitudes, the coastal ocean behaves as a source for atmospheric CO2 but at temperate latitudes, it still behaves as a moderate CO2 sink. A rigorous up-scaling of air-water CO2 fluxes in the coastal ocean is hampered by the poorly constrained estimate of the surface area of inner estuaries. The present estimates clearly indicate the significance of this biogeochemically, highly active region of the biosphere in the global CO2 cycle. [less ▲]Detailed reference viewed: 74 (5 ULg)
Do we have to change our anti-cancer strategy in case of cardiac toxicity ? Point of view of the oncologist.
Conference (2015, January 29)Detailed reference viewed: 15 (2 ULg)
Do we need a new carotid artery stenting trial?
Van Damme, Hendrik ; Defraigne, Jean
in Acta Chirurgica Belgica (2010), 110(4), 432-44
Four well-conducted carotid artery trials comparing carotid artery stenting with carotid artery endarterectomy (EVA-3S, SPACE, ICSS and CREST) could not demonstrate the superiority of carotid artery ... [more ▼]
Four well-conducted carotid artery trials comparing carotid artery stenting with carotid artery endarterectomy (EVA-3S, SPACE, ICSS and CREST) could not demonstrate the superiority of carotid artery stenting (CAS) over carotid artery endarterectomy (CEA). There is at the moment no level-I evidence to support widespread use of endovascular management of carotid artery disease in routine practice. In order to shead some light on the continuing debate on the role of carotid artery stenting, the authors conducted a search in contemporary published literature concerning carotid artery stenting. This extensive literature review reveals a higher peri-procedural stroke-death rate after CAS and a higher cost. Two other events hamper the value of CAS: a higher late restenosis rate and a higher risk of micro-embolisation during the procedure, compared with CEA. The authors conclude that the prevailing overenthusiasm of interventionalists (vascular surgeons, radiologists, cardiologists) for carotid artery stenting is not justified. [less ▲]Detailed reference viewed: 13 (1 ULg)
Do we Need to Solve the Exozodi Question? If Yes, How to Best Solve It?
Absil, Olivier ; ; et al
in Coudé du Foresto, Vincent; Gelino, Dawn; Ribas, Ignasi (Eds.) Pathways Towards Habitable Planets (2010, October 01)
When observing an extrasolar planetary system, the most luminous component after the star itself is generally the light scattered and/or thermally emitted by a population of micron-sized dust grains ... [more ▼]
When observing an extrasolar planetary system, the most luminous component after the star itself is generally the light scattered and/or thermally emitted by a population of micron-sized dust grains. These grains are expected to be continuously replenished by the collisions and evaporation of larger bodies just as in our solar zodiacal cloud. Exozodiacal clouds (“exozodis”) must therefore be seriously taken into account when attempting to directly image faint Earth-like planets (exoEarths, for short). This paper summarizes the oral contributions and discussions that took place during the Satellite Meeting on exozodiacal dust disks, in an attempt to address the following two questions: Do we need to solve the exozodi question? If yes, how to best solve it? [less ▲]Detailed reference viewed: 17 (0 ULg)
Do we need to standardize extraction procedures for community level physiological profiling?
Carnol, Monique ; Bosman, Bernard ; Malchair, Sandrine
Poster (2011, July)
Microorganisms are essential regulators of soil functioning, as they are involved in many crucial processes such as organic matter decomposition, nutrient cycling, soil structure and fertility. Currently ... [more ▼]
Microorganisms are essential regulators of soil functioning, as they are involved in many crucial processes such as organic matter decomposition, nutrient cycling, soil structure and fertility. Currently, there is a growing interest in functional diversity, such as the number and type of substrates used for energy metabolism (CLPP-community level physiological profiling). Such metabolic diversity of heterotroph soil bacteria is frequently investigated through Biolog Ecoplates, containing 31 of the most useful carbon sources for the soil community. The metabolic diversity of soil bacteria might be an interesting biological indicator of soil quality, and also a useful tool for investigating the link between land use change, climate warming, soil carbon, microbial diversity and activity. Methods related to Biolog-CLPP reported in the literature differ in the suspension medium and extraction method, the type and density of inoculums, the inoculation procedures and conditions of incubations. For example, various combinations of extraction methods and suspension media are being used for the first bacterial extraction step. Despite such methodological differences, Biolog-CLPP data are often compared across studies. The development of a standardised method for Biolog-CLPP is however essential improving the relevance and significance of results across studies. In this work, we investigated the influence of extraction procedures on microbial extraction efficiency for further use in CLPP. The microbial extraction efficiency was tested by plate counts for a total of twelve combinations of three suspension media and four extraction methods. The experiment was performed on four soils differing in organic matter content. The aims of this study were to: • Synthesize extraction procedures used for Biolog-CLPP • Measure the effect of extraction procedures on microbial extraction efficiency (plate counts) in four soil types • Investigate a possible interaction between the suspension media and the extraction method used • Evaluate whether a standardized extraction procedure can be recommended across soil types [less ▲]Detailed reference viewed: 93 (12 ULg)
Do we plagiarize more often when the content of the to-be-remembered material is emotional?
Beaufort, Aline ; Brédart, Serge ; et al
Poster (2013, June)
This study examined the impact of the emotional content on rates of cryptomnesia using the Brown and Murphy (1989) paradigm. In a first stage, dyads of young (mean age = 21.5 years) participants (n = 96 ... [more ▼]
This study examined the impact of the emotional content on rates of cryptomnesia using the Brown and Murphy (1989) paradigm. In a first stage, dyads of young (mean age = 21.5 years) participants (n = 96, 48 females) were asked to generate alternately words corresponding to an emotional category (i.e.,“positive”, “negative” or “neutral”). One week later, participants were instructed (1) to recall the items that were generated by themselves and not by the other member of the dyad (Recall-Own task), (2) to generate four news items (Generate-New task) for each category and (3) to assign confidence ratings to their responses. About 17% of responses were plagiarisms in the recall-own task and the percentage almost reached 9% in the Generate-New task. No significant effects of valence were found on rates of plagiarism in Generate-New task nor on the confidence ratings assigned to the participants' responses. However, cryptomnesia was significantly higher for positive than neutral items while it did not differ significantly across negative and neutral items. Confidence ratings were lower for plagiarized responses than for correct responses but these ratings were higher for plagiarized items than for intrusions. [less ▲]Detailed reference viewed: 90 (7 ULg)
Do wildflower strips favor insect pest populations at field margins ?
Hatt, Séverin ; Uyttenbroeck, Roel ; Chevalier Mendes Lopes, Thomas et al
in Agriculture and Agricultural Science Procedia (2015)
Reducing pesticide use is one the major issues of today’s agriculture. Among other possibilities, attracting and conserving pest natural enemies in agricultural landscapes by providing them habitats is ... [more ▼]
Reducing pesticide use is one the major issues of today’s agriculture. Among other possibilities, attracting and conserving pest natural enemies in agricultural landscapes by providing them habitats is promising. Wildflower strips (WFS) sown at field margins are one of these potential habitats. They are known to attract and conserve a large diversity of insects, as they provide them food resources such as pollen and nectar, as well as shelter and overwintering sites. However, the risk of attracting insect pests at field margins may represent an obstacle to their adoption by farmers. Conversely, it would be interesting if such WFS could play the role of pest trap crops. In an experimental field sown with WFS intercropped with oilseed rape (OSR) (Brassica napus L.), its coleopteran pests were trapped in both WFS and OSR using yellow pan traps between April and June 2014. More than 130 000 Meligethes spp., Ceutorhynchus spp. and Psylliodes chrysocephalla (L.) adults were trapped. Meligethes spp., Ceutorhynchus spp. were significantly more abundant in the OSR compared with WFS when adults emerged and populations reached their abundance peak. Before and between these periods, the few adults trapped were significantly more abundant in the WFS compared with the OSR. Concerning P. chrysocephala, too few individuals were caught for analysis. Results showed that OSR was more attractive than WFS when coleopteran pests were abundant. In this study, WFS sown for insect conservation may neither favour insect pest conservation at field margin, nor be considered as trap crops. [less ▲]Detailed reference viewed: 72 (25 ULg)
Do willingness to pay and time trade-off approaches suitably reflect health outcomes in hip and knee osteoarthritis?
Ethgen, Olivier ; ; Lejeune, Eric et al
in Arthritis and Rheumatism (2002, September), 46(number 9 (suppl.)), 73Detailed reference viewed: 16 (4 ULg)
Do you sound or look as old as you are? A study of age estimation in young and older adults
Moyse, Evelyne ; Beaufort, Aline ; Brédart, Serge
in Perception (2012), 41(supplement), 117
Studies on age estimation usually indicated that people are fairly accurate at estimating the age of a person from her/his face or from her/his voice (with an absolute difference of five and ten years ... [more ▼]
Studies on age estimation usually indicated that people are fairly accurate at estimating the age of a person from her/his face or from her/his voice (with an absolute difference of five and ten years respectively) [e.g. Amilon et al., 2000, in: Speaker Classification II. Lectures Notes in Artificial Intelligence, C Müller, Berlin, Springer-Verlag]. However studies showed also that performance depends on the age of participants and the age of stimuli [Rhodes, 2009, Applied Cognitive Psychology, 23, 1-12; Braun, 1996, Forensic Linguistics, 3, 65-73]. The aim of the present study is to compare age estimation performance from faces and voices by using an experimental design in which the age of participants (young vs older), the age of stimuli (young vs older) and the stimulus domain (face vs voice) were crossed. Overall, the age of faces was more accurately estimated than the age of voices. Moreover performance of age estimation was better for young stimuli than for older stimuli. Finally, young participants made smaller absolute errors than older participants. However there is no difference between young and older participants when estimating the age of older stimuli. [less ▲]Detailed reference viewed: 108 (25 ULg)
La doble historia de "El convidado de papel"
Ceballos Viro, Alvaro
in Revista de Literatura (2011), 73(146), 595-622
This article sets out to question the textual history of _El convidado de papel_, a novel by Benjamín Jarnés. The differences between the two firsts editions of this novel, published in 1928 and 1935, are ... [more ▼]
This article sets out to question the textual history of _El convidado de papel_, a novel by Benjamín Jarnés. The differences between the two firsts editions of this novel, published in 1928 and 1935, are more complex than has hitherto been assumed. They also allow to reconstruct a different plot from the one that can be found in literary histories. In its original version, _El convidado de papel_ was not only a peculiar _Bildungsroman_, but also a typical _doppelgänger_ narrative. Therefore, it contained a dense web of intertextual references which Jarnés deliberately eliminated in the second edition of the novel. These intertextual references stimulate the search for new sources as well as the re-evaluation of the precise mode of influence attributed to familiar sources. [less ▲]Detailed reference viewed: 47 (12 ULg)
El doble juego de una vida y de una obra. Jorge Semprun y la literatura comprometida
in Pla, Xavier (Ed.) Jorge Semprun o les espirales de la memoria (2010)Detailed reference viewed: 31 (0 ULg)
Dobutamine cardiac stress testing in conscious healthy dogs
Mc Entee, Kathleen ; Amory, Hélène ; et al
in 6th ESVIM Meeting - Velhoven - Septembre 1996 (1996, September)Detailed reference viewed: 6 (0 ULg)
Dobutamine Stress Echocardiography Versus Quantitative Technetium-99m Sestamibi Spect for Detecting Residual Stenosis and Multivessel Disease after Myocardial Infarction
LANCELLOTTI, Patrizio ; ; Rigo, Pierre et al
in Heart (2001), 86(5), 510-5
OBJECTIVE: To compare the relative accuracy of dobutamine stress echocardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting ... [more ▼]
OBJECTIVE: To compare the relative accuracy of dobutamine stress echocardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting infarct related artery stenosis and multivessel disease early after acute myocardial infarction. DESIGN: Prospective study. SETTING: University hospital. METHODS: 75 patients underwent simultaneous DSE and mibi SPECT at (mean (SD)) 5 (2) days after a first acute myocardial infarct. Quantitative coronary angiography was performed in all patients after imaging studies. RESULTS: Significant stenosis (> 50%) of the infarct related artery was detected in 69 patients. Residual ischaemia was identified by DSE in 55 patients and by quantitative mibi SPECT in 49. The sensitivity of DSE and mibi SPECT for detecting significant infarct related artery stenosis was 78% and 70%, respectively, with a specificity of 83% for both tests. The combination of DSE and mibi SPECT did not change the specificity (83%) but increased the sensitivity to 94%. Mibi SPECT was more sensitive than DSE for detecting mild stenosis (73% v 9%; p = 0.008). The sensitivity of DSE for detecting moderate or severe stenosis was greater than mibi SPECT (97% v 74%; p = 0.007). Wall motion abnormalities with DSE and transient perfusion defects with mibi SPECT outside the infarction zone were sensitive (80% v 67%; NS) and highly specific (95% v 93%; NS) for multivessel disease. CONCLUSIONS: DSE and mibi SPECT have equivalent accuracy for detecting residual infarct related artery stenosis of >/= 50% and multivessel disease early after acute myocardial infarction. DSE is more predictive of moderate or severe infarct related artery stenosis. Combined imaging only improves the detection of mild stenosis. [less ▲]Detailed reference viewed: 13 (1 ULg)