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Peer Reviewed
See detailDevelopment of a non-lethal sampling method to monitor immune response and disease progression in salmonid fish
Collet, Bertrand; Secombes, Chris J; Mira Monte, Milena ULg et al

Poster (2012)

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailDEVELOPMENT OF A NON-LETHAL SAMPLING METHOD TO MONITOR IMMUNE RESPONSE AND DISEASE PROGRESSION IN SALMONID FISH
Collet, Bertrand; Secombes, Chris J; Mira Monte, Milena ULg et al

Conference (2012)

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailDevelopment of a non-lethal sampling method to monitor immune response and disease progression in salmonid fish.
Mira Monte, Milena ULg; Urquhart, Katy; Hoare, Rowena et al

Poster (2013)

Detailed reference viewed: 24 (1 ULg)
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See detailDevelopment of a non-surfactant parenteral formulation of miconazole by the use of cyclodextrins
Piel, Géraldine ULg; Evrard, Brigitte ULg; Fillet, Marianne ULg et al

in International Journal of Pharmaceutics (1998), 169

Miconazole is an antimycotic drug exhibiting a very poor water solubility (B1.03 mg:ml). It has been shown that cyclodextrins (CDs) are able to form inclusion complexes with miconazole and that they are ... [more ▼]

Miconazole is an antimycotic drug exhibiting a very poor water solubility (B1.03 mg:ml). It has been shown that cyclodextrins (CDs) are able to form inclusion complexes with miconazole and that they are able to increase its aqueous solubility. Miconazole is a weak base whose solubility depends of the pH. The purpose of this study was to investigate the influence of both CDs and different acids on the solubility of miconazole. It was found that a synergistic effect existed between CDs and different acids. The combination of hydroxypropyl-bCD (HP-bCD) (100 mM) or sulfobutylether 7-bCD (SBE7-bCD) (50 mM) and lactic acid (50 mM) allowed to dissolve more than 10 mg of miconazole per ml. NMR studies confirmed the formation of an inclusion complex miconazole–CD in an acidic medium. It was also shown by the NMR studies that the complex formed was a 1:1 complex. These results demonstrate that it is possible to develop a parenteral aqueous solution of miconazole without surfactant. [less ▲]

Detailed reference viewed: 85 (1 ULg)
See detailDevelopment of a novel class of biodegradable (co)polyesters
Latere, Jean-Pierre

Doctoral thesis (2002)

Detailed reference viewed: 17 (5 ULg)
Peer Reviewed
See detailDevelopment of a parenteral and of an oral formulation of albendazole with cyclodextrins
Piel, Géraldine ULg; Evrard, Brigitte ULg; Van Hees, Thierry ULg et al

in STP Pharma Sciences (1999), 3

L'albendazole est une dérivé benzimidazole à large spectre d'activité contre les parasites helminthiques de l'homme et de l'animal. L'albendazole est très faiblement soluble dans l'eau. Il a été démontré ... [more ▼]

L'albendazole est une dérivé benzimidazole à large spectre d'activité contre les parasites helminthiques de l'homme et de l'animal. L'albendazole est très faiblement soluble dans l'eau. Il a été démontré que les cyclodextrines sont capables de former des complexes d'inclusion avec l'albendazole et d'en augmenter la solubilité. La solubilité aqueuse de l'albendazole est dépendante du pH. Le but de ce travail est d'étudier l'influence combinée des cyclodextrines et de différents acides sur la solubilité de l'albendazole. Il a été démontré qu'il existe un véritable effet synergique entre les cyclodextrines et les différents acides. L'utilisation combinée d'hydroxypropyl-b-cyclodextrine (200 mM) et d'acide lactique ou acide citrique (50 mM) permet de dissoudre plus de 1 mg/ml d'albendazole. Des études RMN ont démontré l'inclusion de l'albendazole dans la b-cyclodextrine en milieu acide. Ces résultats montrent qu'il est possible de réaliser une solution injectable et une solution orale d'albendazole grâce aux cyclodextrines. [less ▲]

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See detailDevelopment of a performant method for glucocapparin determination in Boscia senegalensis Lam ex. Poir. : A study of the variability
Gueye, Momar Talla; Seck, Dogo; Diallo, Abdoulaye et al

in American Journal of Analytical Chemistry (2013), 4

This study describes a glucocapparin determination method. Based on rapeseed determination of glucosinolate (GSL), the equation of the average straight regression line is Y = 100.42X − 0.03 (R2 = 0.9998 ... [more ▼]

This study describes a glucocapparin determination method. Based on rapeseed determination of glucosinolate (GSL), the equation of the average straight regression line is Y = 100.42X − 0.03 (R2 = 0.9998). Enzymatic hydrolysis of glucocapparin extracted from leaves and fruits of B. senegalensis, analyzed by SPME-GC-MS confirmed the presence of methylisothiocyanate as the main hydrolysis glucocapparin product. Monitoring glucocapparin contents in B. senegalensis leaves and fruits collected in 4 localities in Senegal showed differences between organs according localities and periods of harvest. Glucocapparin content was very high in dry season particularly in January and the lowest rates were recorded during the rainy period between August and November. [less ▲]

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See detailDevelopment of a pharmacological protocol of stress echocardiography in horses
Sandersen, Charlotte ULg

in Annales de Médecine Vétérinaire (2008)

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See detailDevelopment of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression : Synthesis and in vitro evaluation of 9-{3-[18F] Fluoro-1-hydroxy-2-propoxymethyl guanine
Monclus, Michel; Luxen, André ULg; Cool, Vincent et al

in Bioorganic and Medicinal Chemistry Letters (1997), 7(14), 1879-1882

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission ... [more ▼]

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission tomography (PET). [less ▲]

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Peer Reviewed
See detailDevelopment of a practical test of insulin resistance in obese Beagle dogs and effects of sc FOS
Daumas, Caroline; Lhoest, Estelle; Hornick, Jean-Luc ULg et al

in Mussa, P. P.; Nery, J.; Schiavone, A. (Eds.) et al Congress Proceedings 13t h Congress of the ESVCN (2009)

Detailed reference viewed: 41 (1 ULg)
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See detailDevelopment of a predictive model and a risk assessment instrument to facilitate diagnosis of low bone mass in postmenopausal women
Ben Sedrine, Wafa ULg; Chevalier, Th; Micheletti, MC et al

in Arthritis and Rheumatism (2001), 44(1570), 314

Detailed reference viewed: 7 (1 ULg)
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Peer Reviewed
See detailDevelopment of a procedure to simultaneously isolate RNA, DNA, and proteins from characterizing cells invading or cultured on chitosan scaffolds.
Tchemtchoua Tateu, Victor ULg; Atanasova, Ganka; Aqil, Abdelhafid ULg et al

in Analytical Biochemistry (2009), 393(1), 145-7

For many years, chitosan and its derivatives have been considered to be promising biomaterials for tissue engineering and repair. However, information regarding their biological effect on cell phenotype ... [more ▼]

For many years, chitosan and its derivatives have been considered to be promising biomaterials for tissue engineering and repair. However, information regarding their biological effect on cell phenotype is usually limited to evaluation of cell proliferation and survival, overlooking proteomic and transcriptomic analysis. This is largely related to the lack of efficient and quantitative procedures for protein and nucleic acid purification from cells cultured on, or inside, chitosan scaffold. Here we describe an ultracentrifugation procedure enabling the simultaneous and quantitative recovery of high quality RNA, DNA and proteins from cells growing in close contact of biomaterial matrices containing chitosan. [less ▲]

Detailed reference viewed: 113 (16 ULg)
Peer Reviewed
See detailDEVELOPMENT OF A PROTEOMIC PLATFORM TO FACILITATE THE GENERATION OF NEW AND IMPROVED AQUACULTURE VACCINES
Mira Monte, Milena ULg; Causey, Dwight; Stead, David et al

Conference (2016)

Detailed reference viewed: 14 (1 ULg)
Peer Reviewed
See detailDevelopment of a proteomic platform to facilitate the generation of new and improved aquaculture vaccines
Mira Monte, Milena ULg; Causey, Dwight; Stead, David et al

Conference (2016)

Detailed reference viewed: 58 (2 ULg)
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See detailDevelopment of a protocol for micropropagation of Jatropha curcas L
Medza Mve, Samson Daudet ULg; Mergeai, Guy ULg; Baudoin, Jean-Pierre ULg et al

in Fifth International Conference on Renewable Resources and Biorefineries (2009, June 11)

In the present investigation, in vitro clonal propagation of two-month-old Jatropha curcas L. was achieved employing nodal explants. Axillary shoot bud proliferation was best initiated on Murashige and ... [more ▼]

In the present investigation, in vitro clonal propagation of two-month-old Jatropha curcas L. was achieved employing nodal explants. Axillary shoot bud proliferation was best initiated on Murashige and Skoog’s (MS) basal medium supplemented with N6-benzyladenine (BA) and adenine sulphate. This medium allowed the production of 3.1 ± 0.5 shoots per nodal explant with 3.5 ± 0.8 cm average length after 3-4 weeks. [less ▲]

Detailed reference viewed: 25 (6 ULg)