Extracellular catalase production by Aspergillus phoenicis.; ; Destain, Jacqueline et alPoster (2004, May) Detailed reference viewed: 8 (1 ULg) The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species; ; et al in Journal of Molecular Biology (2007), 369 We have studied the effects of the extracellular molecular chaperone, clusterin, on the in vitro aggregation of mutational variants of human lysozyme, including one associated with familial amyloid ... [more ▼] We have studied the effects of the extracellular molecular chaperone, clusterin, on the in vitro aggregation of mutational variants of human lysozyme, including one associated with familial amyloid disease. The aggregation of the amyloidogenic variant I56T is inhibited significantly at clusterin to lysozyme ratios as low as 1:80 (i.e. one clusterin molecule per 80 lysozyme molecules). Experiments indicate that under the conditions where inhibition of aggregation occurs, clusterin does not bind detectably to the native or fibrillar states of lysozyme, or to the monomeric transient intermediate known to be a key species in the aggregation reaction. Rather, it seems to interact with oligomeric species that are present at low concentrations during the lag (nucleation) phase of the aggregation reaction. This behavior suggests that clusterin, and perhaps other extracellular chaperones, could have a key role in curtailing the potentially pathogenic effects of the misfolding and aggregation of proteins that, like lysozyme, are secreted into the extracellular environment. [less ▲] Detailed reference viewed: 30 (1 ULg) Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelopeVanderplasschen, Alain ; ; et alin Proceedings of the National Academy of Sciences of the United States of America (1998), 95 Detailed reference viewed: 4 (0 ULg) Extracellular enveloped vaccinia virus. Entry, egress, and evasion; Vanderplasschen, Alain ![]() in Advances in Experimental Medicine and Biology (1998), 440 Detailed reference viewed: 31 (0 ULg) Extracellular Matrix in Testicular Differentiation; ; et al in Annals of the New York Academy of Sciences (1984), 438 Detailed reference viewed: 4 (0 ULg) Extracellular matrix proteins and basement membrane identification in bovine ovaries and significance for the attachment of cultured preantral follicles; ; Thiry, Marc et alin Theriogenology (1995), 43(5), 845-858 Described in the present paper is the immunolocalization of the extracellular matrix proteins (e.g., fibronectin, collagen Types I and III) in the bovine ovary, with special attention to preantral ... [more ▼] Described in the present paper is the immunolocalization of the extracellular matrix proteins (e.g., fibronectin, collagen Types I and III) in the bovine ovary, with special attention to preantral follicles. In addition, we have shown, histochemically and ultrastructurally, that mechanically isolated bovine preantral follicles are surrounded by an intact basement membrane. After 24 h of culture in serum-free medium, only 20.4% of these follicles attached to a plastic substrate. We showed that covering the plastic with extracellular matrix proteins (i.e., fibronectin, collagen Type I and matrigel) significantly increased the percentage of attached follicles to 76.0, 65.2 and 80.4%, respectively, while laminin had no effect (18.6%). When preantral follicles were embedded within three-dimensional collagen gels, no loss of follicles was observed. Restoring surface interactions between preantral follicles and the extracellular matrix in vitro, either in a two- or a three-dimensional system, might be important for maintaining follicular viability and growth in the future. [less ▲] Detailed reference viewed: 19 (0 ULg) Extracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to appearance of early markers of tumor progression.; ; et al in Cancer Research (1992), 52(10), 2966-76 Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer ... [more ▼] Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer. Using the techniques of immunohistochemistry and immunofluorescence, we show that cell-matrix interactions via the cell surface integrin receptors alpha 3 beta 1, alpha 5 beta 1, alpha 6 beta 4, the Mr 67,000 laminin receptor (67LR) laminin-binding protein, and the secreted matrix protein laminin are strictly regulated during differentiation of mouse epidermis. While alpha 6 beta 4 and alpha 5 beta 1 are polarized to the basal surface of basal cells in contact with the basement membrane, alpha 3 beta 1 and the non-integrin 67LR are primarily detected in the cell periphery of suprabasal cells, where cell to cell contacts are found. Sequential changes in expression of matrix receptors occur following multistage carcinogenesis of mouse skin. In an analysis of benign and malignant skin tumors induced by chemical carcinogens or oncogene transduction, we found that alpha 3 beta 1 and alpha 5 beta 1 as well as the non-integrin 67LR are sequentially down-regulated in the progression from benign to malignant, while alpha 6 beta 4 is the predominant receptor expressed in the carcinomas. Tumor expression of alpha 6 beta 4 is not polarized and is dissociated from its colocalized normal partner bullous pemphigoid antigen, which remains restricted to the basement membrane. The changes in matrix receptors are linked to appearance of keratin 13 in suprabasal regions, but always in alpha 6 beta 4 negative cells. The predominance of alpha 6 beta 4 in the proliferating cells during progression is associated with decreased expression of keratin 13 in carcinomas. These results suggest that matrix interactions with its receptors are important determinants of ordered differentiation in normal skin and show characteristic alterations during carcinogenesis that parallel changes in differentiation of the tumors. [less ▲] Detailed reference viewed: 6 (0 ULg) Extracellular Sugar-Phosphates are Assimilated by Streptomyces in a PhoP-dependent MannerTenconi, Elodie ; Jourdan, Samuel ; Motte, Patrick et alin Antonie van Leeuwenhoek (2012) Detailed reference viewed: 18 (6 ULg) Extracellular, penicillin-resistant DD-carboxypeptidase from Streptomyces SP [abstract]; Ghuysen, Jean-Marie ; et alin Xe Congresso Internacional de Microbiologica - Resumenes - abstracts - résumés (1970) Detailed reference viewed: 4 (0 ULg) Extracorporeal membrane oxygenation (ECMO) in ICU patients suffering from cardiogenic shock, refactory hypoxemia or cardiac arrestMASSION, Paul ; LEDOUX, Didier ; PIRET, Sonia et alin Revue Médicale de Liège (2010) Detailed reference viewed: 27 (2 ULg) Extracting a common high frequency signal from Northern Quebec black spruce tree-rings with a Bayesian hierarchical modelBoreux, Jean-Jacques ; ; et alin Climate of the Past (2009), 5 One basic premise of dendroclimatology is that tree rings can be viewed as climate proxies, i.e. rings are assumed to contain some hidden information about past climate. From a statistical perspective ... [more ▼] One basic premise of dendroclimatology is that tree rings can be viewed as climate proxies, i.e. rings are assumed to contain some hidden information about past climate. From a statistical perspective, this extraction problem can be understood as the search of a hidden variable which represents the common signal within a collection of tree-ring width series. Classical average-based techniques used in dendrochronology have been applied to estimate the mean behavior of this latent variable. Still, depending on tree species, regional factors and statistical methods, a precise quantification of uncertainties associated to the hidden variable distribution is difficult to assess. To model the error propagation throughout the extraction procedure, we propose and study a Bayesian hierarchical model that focuses on extracting an inter-annual high frequency signal. Our method is applied to black spruce (Picea mariana) tree-rings recorded in Northern Quebec and compared to a classical average-based techniques used by dendrochronologists. [less ▲] Detailed reference viewed: 56 (16 ULg) Extracting high resolution records of deformation from well-imaged sections; ; Hubert, Aurelia ![]() in Abstracts with Programs - Geological Society of America (2006, October), 38(7), 132 Detailed reference viewed: 11 (4 ULg) Extracting Intra-Domain Topology from mrinfo Probing; ; Donnet, Benoît et alin 11th international Conference on Passive and active Measurement (2010, April) Activeandpassivemeasurementsfortopologydiscoveryhave known an impressive growth during the last decade. If a lot of work has been done regarding inter-domain topology discovery and modeling, only a few ... [more ▼] Activeandpassivemeasurementsfortopologydiscoveryhave known an impressive growth during the last decade. If a lot of work has been done regarding inter-domain topology discovery and modeling, only a few papers raise the question of how to extract intra-domain topologies from measurements results. In this paper, based on a large dataset collected with mrinfo, a multicast tool that silently discovers all interfaces of a router, we provide a mechanism for retrieving intra-domain topologies. The main challenge is to assign an AS number to a border router whose IP addresses are not mapped to the same AS. Our algorithm is based on probabilistic and empirical IP allocation rules. The goal of our pool of rules is to converge to a consistent router to AS mapping. We show that our router-to-AS algorithm results in a mapping in more than 99% of the cases. Furthermore, with mrinfo, point-to-point links between routers can be distinguished from multiple links attached to a switch, providing an accurate view of the collected topologies. Finally, we provide a set of large intra-domain topologies in various formats. [less ▲] Detailed reference viewed: 2 (0 ULg) Extracting laws of decay in the femto-picosecond range from autocorrelation functionsRemacle, Françoise ; Desouter, Michèle ; in Journal of Chemical Physics (1989), 91 Detailed reference viewed: 3 (1 ULg) Extraction and characterisation of a dietary fibre concentrate from date pulp; Blecker, Christophe ; et alPoster (2006, June) Detailed reference viewed: 4 (0 ULg) EXTRACTION AND CHARACTERIZATION OF ARABINOXYLANS FROM SPELT BRAN AND HEMICELLULOSES FROM SPELT HULL BY CHEMICAL AND ENZYMATICAL METHODSEscarnot, Emmanuelle ![]() Doctoral thesis (2012) Detailed reference viewed: 18 (5 ULg) Extraction And Characterization Of Water-Extractable And Water-Unextractable Arabinoxylans From Spelt Bran: Study Of The Hydrolysis Conditions For Monosaccharides Analysis.Escarnot, Emmanuelle ; Aguedo, Mario ; et alin Journal of Cereal Science (2011) Detailed reference viewed: 29 (12 ULg) Extraction and Clean-Up of Milk Samples for PCDD/Fs and cPCBs AnalysisFocant, Jean-François ; De Pauw, Edwin ![]() in Organohalogen Compounds (2001), 50 Detailed reference viewed: 11 (0 ULg) Extraction and fractionation of cytotoxic metabolites from Galanthus lagodechianus Kem.-Nath; ; et al in Allergology and Immunology (Moscou) (2006), 7 Detailed reference viewed: 17 (1 ULg) Extraction and partial purification of tomato leaves hydroperoxide lyaseFauconnier, Marie-Laure ; ; Poster (1995, September 27) Detailed reference viewed: 10 (1 ULg) |
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