Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailDre-miR-2188 Targets Nrp2a and Mediates Proper Intersegmental Vessel Development in Zebrafish Embryos.
Soares, Ana R.; Reverendo, Marisa; Pereira, Patricia M. et al

in PLoS ONE (2012), 7(6), 39417

BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed ... [more ▼]

BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed for miRNA target prediction however, experimental validation is still essential for the correct identification of miRNA targets. We have recently predicted that Neuropilin2a (Nrp2a), a vascular endothelial growth factor receptor which is essential for normal developmental angiogenesis in zebrafish, is a dre-miR-2188 target. METHODOLOGY: Here we show that dre-miR-2188 targets the 3'-untranslated region (3'UTR) of Nrp2a mRNA and is implicated in proper intersegmental vessel development in vivo. Over expression of miR-2188 in zebrafish embryos down regulates Nrp2a expression and results in intersegmental vessel disruption, while its silencing increases Nrp2a expression and intersegmental vessel sprouting. An in vivo GFP sensor assay based on a fusion between the GFP coding region and the Nrp2a 3'UTR confirms that miR-2188 binds to the 3'UTR of Nrp2a and inhibits protein translation. CONCLUSIONS: We demonstrate that miR-2188 targets Nrp2a and affects intersegmental vessel development in zebrafish embryos. [less ▲]

Detailed reference viewed: 27 (1 ULg)
Full Text
Peer Reviewed
See detailDREAM 2012: DEVELOPMENT OF LAPAROSCOPIC SURGERY AT THE UNIVERSITY HOSPITAL OF KINSHASA, DRC
Nsadi Fwene, Berthier ULg; Veyi, D; Kazadi, J et al

in Acta Chirurgica Belgica (2012, May), 112(3), 8240

Objectives: The technical nature of laparoscopy, and the required specific laparoscopic tools and medical skills, may render this approach difficult in developing countries. We hypothesized that ... [more ▼]

Objectives: The technical nature of laparoscopy, and the required specific laparoscopic tools and medical skills, may render this approach difficult in developing countries. We hypothesized that laparoscopy may be developed in the Cliniques Universitaires de Kinshasa (CUK), and may be cost-effective. The final aim of this program is to bring the benefits of laparoscopy to the DRC population, by allowance of adequate training on the UNIKIN personnel, including anaesthetists, surgeons and nurses, who in the future will have to locally form the DRC medical and nursery students. Methods: With the financial support from Wallonie-Bruxelles International (WBI), a complete CUK team, including a surgeon (2 years training in Belgium), an anaesthetist and nurses, were trained in Belgium and then afterwards in DRC. The laparoscopic equipment was sent to Kinshasa, and three theoretical and practical missions of Belgian teams were organised. Results: Over a 2 year period, 116 laparoscopic procedure were performed, including 32 appendectomies, 41 cholecystectomies, 11 hernia repairs, 9 laparoscopy explorations for peritoneal carcinoma assessment and biopsy, 8 procedures for catheter of dialysis peritoneal, 5 gynecologics procedures, and 10 other miscellaneous procedures. Conclusions: A joined approach, taking into account on one hand the training of the skills locally trained to adapt itself to some difficulties, on the other hand institutions of scientific support and a real program and local will of development of this new procedure are the wages of development, accessibility and durability of such news approach in developing countries. All University and non-University team willing to join such a project are welcome. [less ▲]

Detailed reference viewed: 37 (3 ULg)
Full Text
Peer Reviewed
See detailDREAM 2020: Development of laparoscopic surgery and endoscopy in the university hospital of Kinshasa, DRC
Nsadi, Berthier; Veyi, D.; Kazadi, J. et al

in Acta Gastro-Enterologica Belgica (2011, March), 74(1), 14

Detailed reference viewed: 49 (4 ULg)
Full Text
Peer Reviewed
See detailDream and emotion regulation: insight from the ancient art of memory.
Desseilles, Martin ULg; Duclos, Catherine

in The Behavioral and brain sciences (2013), 36(6), 614634-59

During dreaming, as well as during wakefulness, elaborative encoding, indexing and ancient art of memory (AAOM) techniques, such as the method of loci, may coincide with emotion regulation. These ... [more ▼]

During dreaming, as well as during wakefulness, elaborative encoding, indexing and ancient art of memory (AAOM) techniques, such as the method of loci, may coincide with emotion regulation. These techniques shed light on the link between dreaming and emotional catharsis, post-traumatic stress disorder, supermemorization during sleep as opposed to wakefulness, and the developmental role of rapid eye movement (REM) sleep in children. [less ▲]

Detailed reference viewed: 53 (0 ULg)
Full Text
Peer Reviewed
See detailDreaming: a neuroimaging view
Dang Vu, Thien Thanh ULg; Desseilles, Martin ULg; Albouy, Geneviève ULg et al

in Schweizer Archiv Fur Neurologie und Psychiatrie (2005), 156

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailDreaming: A Neuropsychological View
Schwartz, Sophie; Dang Vu, Thien Thanh ULg; Ponz, Aurelie et al

in Schweizer Archiv für Neurologie und Psychiatrie = Archives Suisses de Neurologie et de Psychiatrie = Archivio Svizzero di Neurologia e Psichiatria (2005), 156(8), 426-439

Detailed reference viewed: 14 (0 ULg)
See detailDrei Auferweckungsszenen Lüttich (?) um 1030-1050
George, Philippe ULg

in Canossa. Erschütterung der Welt, t. II Catalogue n° 453, p. 348-350. (2007)

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailDrei Thesen zur Literaturdidaktik im Fremdsprachenunterricht
Vanhaegendoren, Koen ULg

in Epos. Revista de filología (2004), 20-21

Detailed reference viewed: 82 (2 ULg)
Full Text
See detailDas Drei-Körper-Coulombproblem unter periodischem Antrieb
Schlagheck, Peter ULg

Doctoral thesis (1999)

Detailed reference viewed: 42 (14 ULg)
Full Text
Peer Reviewed
See detailDrift potential of tilted shielded rotary atomisers based on wind tunnel measurements
Ouled Taleb Salah, Sofiene ULg; Massinon, Mathieu ULg; De Cock, Nicolas ULg et al

in 67th International Symposium on Crop Protection (2015, May 19)

Detailed reference viewed: 34 (6 ULg)
Full Text
Peer Reviewed
See detailA drifting impact oscillator with periodic impulsive loading: Application to percussive drilling
Depouhon, Alexandre ULg; Denoël, Vincent ULg; Detournay, Emmanuel

in Physica D: Nonlinear Phenomena (2013), 258(0), 1--10

Detailed reference viewed: 23 (2 ULg)
See detailDrivers of inorganic carbon dynamics in first-year sea ice: A model study
Moreau, S.; Vancoppenolle, M.; Delille, Bruno ULg et al

Conference (2015, May 16)

Sea ice is an active source or a sink for carbon dioxide (CO2), although to what extent is not clear. Here, we analyze CO2 dynamics within sea ice using a one-dimensional halo-thermodynamic sea ice model ... [more ▼]

Sea ice is an active source or a sink for carbon dioxide (CO2), although to what extent is not clear. Here, we analyze CO2 dynamics within sea ice using a one-dimensional halo-thermodynamic sea ice model including gas physics and carbon biogeochemistry. The ice-ocean fluxes, and vertical transport, of total dissolved inorganic carbon (DIC) and total alkalinity (TA) are represented using fluid transport equations. Carbonate chemistry, the consumption and release of CO2 by primary production and respiration, the precipitation and dissolution of ikaite (CaCO3•6H2O) and ice-air CO2 fluxes, are also included. The model is evaluated using observations from a 6-month field study at Point Barrow, Alaska and an ice-tank experiment. At Barrow, results show that the DIC budget is mainly driven by physical processes, wheras brine-air CO2 fluxes, ikaite formation, and net primary production, are secondary factors. In terms of ice-atmosphere CO 2 exchanges, sea ice is a net CO2 source and sink in winter and summer, respectively. The formulation of the ice-atmosphere CO2 flux impacts the simulated near-surface CO2 partial pressure (pCO2), but not the DIC budget. Because the simulated ice-atmosphere CO2 fluxes are limited by DIC stocks, and therefore < 2 mmol m-2 day-1, we argue that the observed much larger CO2 fluxes from eddy covariance retrievals cannot be explained by a sea ice direct source and must involve other processes or other sources of CO2. Finally, the simulations suggest that near surface TA/DIC ratios of 2, sometimes used as an indicator of calcification, would rather suggest outgassing. [less ▲]

Detailed reference viewed: 25 (0 ULg)
Full Text
Peer Reviewed
See detailDrivers of inorganic carbon dynamics in first-year sea ice: A model study.
Moreau, Sebastien; Vancoppenolle, Martin; Delille, Bruno ULg et al

in Journal of Geophysical Research. Oceans (2015), 120

Sea ice is an active source or a sink for carbon dioxide (CO2), although to what extent is not clear. Here, we analyze CO2 dynamics within sea ice using a one-dimensional halo-thermodynamic sea ice model ... [more ▼]

Sea ice is an active source or a sink for carbon dioxide (CO2), although to what extent is not clear. Here, we analyze CO2 dynamics within sea ice using a one-dimensional halo-thermodynamic sea ice model including gas physics and carbon biogeochemistry. The ice-ocean fluxes and vertical transport of total dissolved inorganic carbon (DIC) and total alkalinity (TA) are represented using fluid transport equations. [less ▲]

Detailed reference viewed: 46 (9 ULg)
Full Text
Peer Reviewed
See detailDrivers of the winter–spring phytoplankton bloom in a pristine NW Mediterranean site, the Bay of Calvi (Corsica): A long-term study (1979–2011)
Goffart, Anne ULg; Hecq, Jean-Henri ULg; Legendre, Louis

in Progress in Oceanography (2015), 137

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics ... [more ▼]

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics (31 years), chlorophyll a (chl a, 15 years), and inorganic nutrients (13 years). Because samples were collected at relatively high frequencies, which ranged from daily to biweekly during the winter-spring period, it was possible to (1) evidence the key role of two interacting physical variables, i.e. water temperature and wind intensity, on nutrient replenishment and phytoplankton dynamics during the winter-spring period, (2) determine critical values of physical factors that explained interannual variability in the replenishment of surface nutrients and the winter-spring phytoplankton bloom, and (3) identify previously unrecognized characteristics of the planktonic ecosystem. Over the >30 year observation period, the main driver of nutrient replenishment and phytoplankton (chl a) development was the number of wind events (mean daily wind speed >5 m s-1) during the cold-water period (subsurface water ≤13.5°C). According to winter intensity, there were strong differences in both the duration and intensity of nutrient fertilization and phytoplankton blooms (chl a). The trophic character of the Bay of Calvi changed according to years, and ranged from very oligotrophic (i.e. subtropical regime, characterized by low seasonal variability) to mesotrophic (i.e. temperate regime, with a well-marked increase in nutrient concentrations and chl a during the winter-spring period) during mild and moderate winters, respectively. A third regime occurred during severe winters characterized by specific wind conditions (i.e. high frequency of northeasterly winds), when Mediterranean “high nutrient - low chlorophyll” conditions occurred as a result of enhanced cross-shore exchanges and associated offshore export of the nutrient-rich water. There was no long-term trend (e.g. climatic) in either nutrient replenishment or the winter-spring phytoplankton bloom between 1979 and 2011, but both nutrients and chl a reflected interannual and decadal changes in winter intensity. [less ▲]

Detailed reference viewed: 45 (13 ULg)
Full Text
See detailDrivers on carbon dioxide emissions from the Scheldt river basin
Gypens, N; Passy, P; Garnier, J et al

Poster (2014, April 27)

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailDrivers, mechanisms and long-term variability of seasonal hypoxia on the Black Sea northwestern shelf – is there any recovery after eutrophication?
Capet, Arthur ULg; Beckers, Jean-Marie ULg; Grégoire, Marilaure ULg

in Biogeosciences (2013), 10

The Black Sea northwestern shelf (NWS) is a shallow eutrophic area in which the seasonal stratification of the water column isolates the bottom waters from the atmosphere. This prevents ventilation from ... [more ▼]

The Black Sea northwestern shelf (NWS) is a shallow eutrophic area in which the seasonal stratification of the water column isolates the bottom waters from the atmosphere. This prevents ventilation from counterbalancing the large consumption of oxygen due to respiration in the bottom waters and in the sediments, and sets the stage for the development of seasonal hypoxia. A three-dimensional (3-D) coupled physical–biogeochemical model is used to investigate the dynamics of bottom hypoxia in the Black Sea NWS, first at seasonal and then at interannual scales (1981–2009), and to differentiate its driving factors (climatic versus eutrophication). Model skills are evaluated by a quantitative comparison of the model results to 14 123 in situ oxygen measurements available in the NOAA World Ocean and the Black Sea Commission databases, using different error metrics. This validation exercise shows that the model is able to represent the seasonal and interannual variability of the oxygen concentration and of the occurrence of hypoxia, as well as the spatial distribution of oxygen-depleted waters. During the period 1981–2009, each year exhibits seasonal bottom hypoxia at the end of summer. This phenomenon essentially covers the northern part of the NWS – which receives large inputs of nutrients from the Danube, Dniester and Dnieper rivers – and extends, during the years of severe hypoxia, towards the Romanian bay of Constanta. An index H which merges the aspects of the spatial and temporal extension of the hypoxic event is proposed to quantify, for each year, the intensity of hypoxia as an environmental stressor. In order to explain the interannual variability of H and to disentangle its drivers, we analyze the long time series of model results by means of a stepwise multiple linear regression. This statistical model gives a general relationship that links the intensity of hypoxia to eutrophication and climate-related variables. A total of 82% of the interannual variability of H is explained by the combination of four predictors: the annual riverine nitrate load (N), the sea surface temperature in the month preceding stratification (Ts), the amount of semi-labile organic matter accumulated in the sediments (C) and the sea surface temperature during late summer (Tf). Partial regression indicates that the climatic impact on hypoxia is almost as important as that of eutrophication. Accumulation of organic matter in the sediments introduces an important inertia in the recovery process after eutrophication, with a typical timescale of 9.3 yr. Seasonal fluctuations and the heterogeneous spatial distribution complicate the monitoring of bottom hypoxia, leading to contradictory conclusions when the interpretation is done from different sets of data. In particular, it appears that the recovery reported in the literature after 1995 was overestimated due to the use of observations concentrated in areas and months not typically affected by hypoxia. This stresses the urgent need for a dedicated monitoring effort in the Black Sea NWS focused on the areas and months concerned by recurrent hypoxic events. [less ▲]

Detailed reference viewed: 36 (8 ULg)