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See detailA DESIGN SPACE APPROACH TO DEVELOP A GENERIC CE METHOD FOR THE SEPARATION OF 19 ANTIMALARIAL DRUGS
Lamalle, Caroline ULg; Marini Djang'Eing'A, Roland ULg; Debrus, Benjamin ULg et al

Poster (2010, September)

This project consists in analysing different molecules used against malaria by capillary electrophoresis (CE).

Detailed reference viewed: 78 (20 ULg)
Peer Reviewed
See detailDesign Space for analytical methods. A Bayesian perspective based on multivariate models and prediction
Lebrun, Pierre ULg; Boulanger, Bruno ULg; Jullion, Astrid et al

Conference (2008, September)

Detailed reference viewed: 39 (13 ULg)
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See detailDesign Space for Analytical Methods: Why ? What ? How ?
Rozet, Eric ULg; Debrus, Benjamin ULg; Lebrun, Pierre ULg et al

Conference (2015, January 22)

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See detailDesign Space ou Espace de Conception
Boulanger, B.; Lebrun, Pierre ULg; Rozet, Eric ULg et al

Scientific conference (2011, November 29)

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See detailDesign Spaces for Analytical Methods
Rozet, Eric ULg; Lebrun, Pierre ULg; Debrus, Benjamin ULg et al

in Trends in Analytical Chemistry (2013), 42

Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a Quality by Design (QbD) approach, there have been many discussions on the opportunity for ... [more ▼]

Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a Quality by Design (QbD) approach, there have been many discussions on the opportunity for analytical method developments to follow a similar approach. A key component of the QbD paradigm is the definition of the Design Space of analytical methods where assurance of quality is provided. Several Design Spaces for analytical methods have been published, stressing the importance of this concept. This paper aims at explaining what is an analytical method Design Space, why it is useful for the robust development and optimization of analytical methods and how to build such a Design Space. A strong emphasis is made by distinguishing the usual mean response surface approach, overlapping mean response surfaces and the desirability function one to other probabilistic approaches as only these last ones correctly define a Design Space. In addition, recent publications assessing the Design Space of analytical methods are reviewed and discussed. [less ▲]

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See detailDesign status of ASPIICS, an externally occulted coronagraph for PROBA-3
Renotte, Etienne ULg; Alia, A.; Bemporad, A. et al

in Proc. SPIE Volume 9604 Solar Physics and Space Weather Instrumentation VI (2015, September 21)

The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona ... [more ▼]

The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona, as well as phenomena that lead to coronal mass ejections (CMEs), which influence space weather. Improvement on this front requires eclipse-like conditions over long observation times. The space-borne coronagraphs flown so far provided a continuous coverage of the external parts of the corona but their over-occulting system did not permit to analyse the part of the white-light corona where the main coronal mass is concentrated. The proposed PROBA-3 Coronagraph System, also known as ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), with its novel design, will be the first space coronagraph to cover the range of radial distances between ~1.15 and 3 solar radii where the magnetic field plays a crucial role in the coronal dynamics, thus providing continuous observational conditions very close to those during a total solar eclipse. PROBA-3 is first a mission devoted to the in-orbit demonstration of precise formation flying techniques and technologies for future European missions, which will fly ASPIICS as primary payload. The instrument is distributed over two satellites flying in formation (approx. 150m apart) to form a giant coronagraph capable of producing a nearly perfect eclipse allowing observing the sun corona closer to the rim than ever before. The coronagraph instrument is developed by a large European consortium including about 20 partners from 7 countries under the auspices of the European Space Agency. This paper is reviewing the recent improvements and design updates of the ASPIICS instrument as it is stepping into the detailed design phase. [less ▲]

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See detailDesign Synthesis and Use of Polypeptides as Biosynthetic Nanomachines
Asano, Marie ULg

Conference (2014, March)

Detailed reference viewed: 5 (2 ULg)
See detailDesign Synthesis and Use of Polypeptides as Biosynthetic Nanomachines
Asano, Marie ULg

Conference (2015, March)

Detailed reference viewed: 7 (2 ULg)
See detailDesign Synthesis and Use of Polypeptides as Biosynthetic Nanomachines
Asano, Marie ULg

Scientific conference (2015)

Detailed reference viewed: 10 (3 ULg)
See detailDesign Synthesis and Use of Polypeptides as Biosynthetic Nanomachines
Asano, Marie ULg

Conference (2013, March)

Detailed reference viewed: 3 (2 ULg)
See detailDesign Synthesis and Use of Polypeptides as Model Systems for SMFS
Asano, Marie ULg

Scientific conference (2014, April)

Detailed reference viewed: 9 (4 ULg)
See detailLe "Design Thinking" ou comment décomplex(ifi)er l'accès à la créativité et augmenter votre efficacité
Elsen, Catherine ULg

Conference given outside the academic context (2012)

La pensée créative est à l’innovation ce que les méthodes sont à la recherche scientifique: une base essentielle. Longtemps associés à une certaine part de mystère, les mécanismes intrinsèques de la ... [more ▼]

La pensée créative est à l’innovation ce que les méthodes sont à la recherche scientifique: une base essentielle. Longtemps associés à une certaine part de mystère, les mécanismes intrinsèques de la créativité sont aujourd’hui peu à peu décryptés par les communautés de chercheurs actifs en ingénierie de la conception, en sciences sociales ou en psychologie. Un consensus semble se dégager quant à l’étendue de son application: la véritable valeur ajoutée de la créativité apparaît lorsqu’elle est appliquée, telle une culture d’entreprise, à toutes les strates d’un projet et lorsqu’elle est mise en oeuvre, sans distinction, par tout un chacun. Forts de ce constat, des entrepreneurs et inventeurs tels que David Kelley (fondateur d’IDEO, directeur de la d.school, Université de Stanford) ou Tim Brown (CEO actuel d’IDEO) ont activement développé une approche appelée le "Design Thinking". Celle-ci vise à démystifier et «décomplex(ifi)er» certains procédés favorisant la créativité et ainsi parvenir à décomplexer les acteurs généralement considérés comme «non créatifs». L’intervention abordera, au travers d’une vingtaine de «success stories», les concepts de base de la démarche. Elle se voudra avant tout à la portée de ceux et celles qui désirent ré-intégrer la créativité au sein de leur pratique professionnelle et, en finalité, augmenter leur potentiel innovant. [less ▲]

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See detailLe Design Thinking: de la "boîte noire" du designer à la boîte à outil de l'innnovateur
Elsen, Catherine ULg; Cornet, Adeline ULg

Article for general public (2012)

Ce premier article du blog d'ID Campus révèle au grand public les facettes du Design Thinking.

Detailed reference viewed: 177 (12 ULg)
See detailDesign Thinking: l'approche empathique, clé de voûte de l'entreprise créative ?
Elsen, Catherine ULg

Conference given outside the academic context (2014)

La posture créative est à l’innovation ce que l’excellence opérationnelle est à l’entreprise: une démarche désormais incontournable. Et pourtant les plus sceptiques poussent nos communautés, avec raison ... [more ▼]

La posture créative est à l’innovation ce que l’excellence opérationnelle est à l’entreprise: une démarche désormais incontournable. Et pourtant les plus sceptiques poussent nos communautés, avec raison, à poursuivre la réflexion: que reste-t-il à apprendre des méthodes créatives divergentes, comme le brainstorming par exemple ? Comment éviter à l’avenir la mise en œuvre répétitive et décontextualisée de recettes « toutes faites » qui dénaturent la créativité et nuisent à sa crédibilité ? Ces inquiétudes seront analysées par Catherine Elsen à la lumière du Design Thinking, cette approche méthodologique qui pourrait bien faire favorablement évoluer les représentations et accompagner chaque entreprise dans la mise en œuvre d’un modèle créatif qui lui correspond réellement. Esquissée dès la fin des années 80 aux Etats-Unis par des entrepreneurs et innovateurs tels que David Kelley (fondateur d’IDEO, directeur de la d.school, Université de Stanford) ou Tim Brown (CEO actuel d’IDEO), la méthode repose sur deux piliers fondamentaux: l’approche empathique (du marché, des utilisateurs, mais aussi de l’entreprise elle-même) et le « quick and rough prototyping » (ou « protocept »), soit une matérialisation itérative précoce des idées, que certains qualifient d’agile. L’intervention abordera ces fondamentaux théoriques et leur mise en œuvre pratique au travers d’exemples d’applications et d’outils ré-appropriables. [less ▲]

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See detailDesign Thinking: une approche à intégrer à nos pratiques pour renforcer le potentiel d'innovation technologique en Wallonie ?
Elsen, Catherine ULg; Réseau Easynove

Conference given outside the academic context (2015)

Detailed reference viewed: 59 (0 ULg)
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See detailDesign tools for outdoor comfort assessment
Teller, Jacques ULg

Scientific conference (1998)

Detailed reference viewed: 38 (4 ULg)
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Peer Reviewed
See detailDesign, Construction and Validation of a Guarded Hot Plate Apparatus for Thermal Conductivity Measurement of High Thickness Crop-Based Specimens
Dubois, Samuel ULg; Lebeau, Frédéric ULg

in Materials and Structures (2013)

The search for sustainability achievement in the building sector led to the use of crop-based insulation materials. Among these, raw products like plant straws bales can present elementary representative ... [more ▼]

The search for sustainability achievement in the building sector led to the use of crop-based insulation materials. Among these, raw products like plant straws bales can present elementary representative volumes (REVs) in the size order of several square centimeters. Fibers orientation may play an important role on material thermal behavior. Measuring their thermal conductivities with standard steady-state equipment can thus lead to some inaccuracies due to the necessity of resetting lower thickness samples. This paper presents a Guarded Hot Plate (GHP) apparatus designed to test high thickness samples, up to 40cm, with an accuracy of 2%. The different parts of the machine are described in details along with design process and challenges encountered. Temperature and heat flux measurements in the device represent critical design stages where optimal accuracy is needed in order to optimize the resulting global error. Regarding this, necessary numerical and experimental analyzes were conducted emphasizing on intrinsic systematic error assessment. To complete the study, some validations tests are performed on a reference material and other widely-spread polystyrene slabs. These tests take into account the optimal computation parameters resulting from the numerical analysis and the apparatus proved to be in accordance with accuracy requirements. [less ▲]

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Peer Reviewed
See detailDesign, fabrication and testing of tunable microcavities for atom chips
Srinivasan, P; Gollasch, CO; Kraft, Michael ULg

in Proc. Eurosensors XXIII Conference (2009)

Detailed reference viewed: 11 (0 ULg)