Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailEffect of serum dilution on binding of cortisol to thermolabile and thermostable serum proteins
Demey-Ponsart, E.; Foidart, Jean-Michel ULg; Hendrickx, J. C. et al

in Journal of Steroid Biochemistry (1977), 8(10), 1091-5

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailEffect of sexual genotype on the reproductive biology of the Nile tilapia, O.niloticus.
Rougeot, Carole ULg; Badiane, A. A.; Prignon, Christian ULg et al

Poster (2007, June)

Detailed reference viewed: 47 (5 ULg)
Full Text
Peer Reviewed
See detailThe Effect of Shape, Age and Extension on the Compliance of Equine Tracheal Segments
Art, Tatiana ULg; Lekeux, Pierre ULg

in Veterinary Research Communications (1991), 15(2), 135-146

The influence of the age and weight of the animal as well as that of the extension and the shape of the trachea on the mechanical properties of the cervical trachea was studied in 33 isolated tracheal ... [more ▼]

The influence of the age and weight of the animal as well as that of the extension and the shape of the trachea on the mechanical properties of the cervical trachea was studied in 33 isolated tracheal segments obtained from freshly slaughtered horses. The relationship between intraluminal pressure and volume was determined in the cervical tracheal segments positioned firstly under normal longitudinal tension and secondly in hyperextension. At the same time, changes in the area of the cross-section of the lumen (X-SA) at the midpoint of the segment were measured using photographs obtained by slit-lamp transillumination and endoscopy. The sagittal (DS) and transverse (DT) diameters were determined for each segment and the DT/DS ratio was calculated to give an estimate of the shape of the X-SA. The results showed that (i) neither the age nor the weight of the horses had any influence on the mechanical properties of the trachea; (ii) extension decreases the compressibility of the tracheal segment in vitro; (iii) there is a wide variation in the extrathoracic tracheal X-SA shape in horses; and (iv) the shape of the X-SA has a major influence on the mechanical properties of the trachea. It was concluded that (i) hyperextension of the neck will partly facilitate respiration at high levels of ventilation by elongating the trachea and by decreasing its collapsibility; and (ii) the tracheal collapse which may occur during high levels of ventilation will be more or less important depending on the individual X-SA shape. [less ▲]

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailEffect of short-chain fructooligosaccharide-enriched energy-restricted diet on weight loss and serum haptoglobin concentration in Beagle dogs.
Ricci, Rebecca; Jeusette, Isabelle; Godeau, Jean-Marie ULg et al

in British Journal of Nutrition (2011), 106

The effects of the dietary inclusion of two levels of short-chain fructooligosaccharides (sc-FOS) on weight loss, biochemical parameters and serum haptoglobin concentration were investigated in twelve ... [more ▼]

The effects of the dietary inclusion of two levels of short-chain fructooligosaccharides (sc-FOS) on weight loss, biochemical parameters and serum haptoglobin concentration were investigated in twelve experimental obese Beagle dogs. Dogs were randomised into two groups and submitted to a weight loss program (WLP): the control group (C) received a commercial energy-restricted high-protein diet containing 1 % DM sc-FOS, whereas the test group (T) received the same diet enriched with sc-FOS to attain a 3 % DM content. Body weight (BW) and body condition score were weekly assessed in each dog and blood was collected before and after WLP to measure total plasma cholesterol (CHOL), TAG, NEFA, glucose (GLUC), insulin, serum leptin and haptoglobin. Groups showed similar BW and blood parameters before treatment. When values before and after treatment of the dogs were compared, significant reductions were observed for all parameters, with the exception of NEFA and GLUC. However, when these reductions were compared between C and T groups, significant differences were detected only for haptoglobin (T before v. T after: 1545 v. 605 mg/l, P = 0.03; C before v. C after: 1635 v. 1400 mg/l, P = NS). Positive correlations between haptoglobin and CHOL and between haptoglobin and TAG were observed before but not after WLP. In conclusion, feeding obese dogs with the energy-restricted diet caused significant weight loss and reduction of blood parameters, irrespective of the sc-FOS content included. However, serum haptoglobin level, and the subclinical inflammatory condition associated with it, was significantly lowered in the T but not in the C group. [less ▲]

Detailed reference viewed: 33 (3 ULg)
Full Text
Peer Reviewed
See detailEffect of short-term oral and inhaled corticosteroids on airway inflammation and responsiveness in a feline acute asthma model
Leemans, Jérôme; Kirschvink, Nathalie; Clercx, Cécile ULg et al

in Veterinary Journal (2011)

The objective of this study was to investigate whether high-dose inhaled fluticasone propionate (FP), alone or in combination with salmeterol (SAL), is as effective as oral prednisolone in reducing airway ... [more ▼]

The objective of this study was to investigate whether high-dose inhaled fluticasone propionate (FP), alone or in combination with salmeterol (SAL), is as effective as oral prednisolone in reducing airway inflammation and obstruction in cats with experimentally-induced acute asthma. Six cats sensitised to Ascaris suum (AS) were enrolled in a prospective controlled therapeutic trial and underwent four aerosol challenges, at 1-month intervals with AS allergen. The allergen - stimulated animals received four consecutive days treatment with either oral prednisolone at 1mg/kg twice daily, 500μg of FP inhaled twice daily, or a combination of FP/SAL at 500μg/50μg inhaled twice daily, respectively, according to a randomised cross-over design. Treatment-related changes in lung function, airway responsiveness (AR) and bronchoalveolar lavage fluid (BALF) cytology were assessed. Barometric whole-body plethysmography (BWBP) was used for the assessment of respiratory variables and AR. No significant differences in respiratory rate or Penh (an estimate of airflow limitation measured by BWBP) were detected among treatment groups. Allergen-induced airway hyper-responsiveness was significantly inhibited by all three steroid treatments (P<0.05). The mean BALF eosinophil percentage (±SEM) was lower after oral and inhaled corticosteroid treatment and these changes were significant for groups receiving prednisolone and the FP/SAL combination. Findings suggest high-dose FP, particularly in combination with SAL, is effective in ameliorating airway inflammation and hyper-responsiveness in this model of acute feline asthma, and highlight the potential use of these drugs in cats experiencing acute exacerbations of the naturally occurring disease. [less ▲]

Detailed reference viewed: 36 (15 ULg)
Full Text
Peer Reviewed
See detailEffect of Show Jumping on Heart Rate, Blood Lactate and Other Plasma Biochemical Values
Art, Tatiana ULg; Amory, Hélène ULg; Desmecht, Daniel ULg et al

in Equine Veterinary Journal. Supplement (1990), 32(9), 78-82

This study investigated some physiological responses to exercise performed by a horse during show jumping. The effects of jumping on heart rate (HR), blood lactate (LA) and some other blood values were ... [more ▼]

This study investigated some physiological responses to exercise performed by a horse during show jumping. The effects of jumping on heart rate (HR), blood lactate (LA) and some other blood values were studied in nine normal horses participating at the Belgian Junior Championship. Venous blood was sampled before and immediately after the show jumping and was analysed for packed cell volume, LA, blood glucose (GLU), total plasma protein, bicarbonate, sodium, potassium (K+), chloride, calcium and activities of plasma lactate dehydrogenase, creatine phosphokinase (CK) aspartate amino transferase and gamma glutamyl transferase (GGT). A heart rate recorder placed under the saddle allowed the continuous recording of HR from the warm-up until 2 mins after the event. The completion of the jumping induced significant changes in all values, except in K, GLU and GGT. Resting values of LA and HR were 0.53 +/- 0.05 mmol/litre and 43.9 +/- 1.9 beats/min respectively. Post exercise LA reached a mean value of 9.04 +/- 0.9 mmol/litre, and, during the jumping, HR rose to a peak of 191.4 +/- 3.8 beats/min. The results of this study demonstrate that, although the speed and duration of such an exercise are low, show jumping represents a severe exertion which requires the use of anaerobic metabolism. This implies that the training schedule of jumpers must include power training in order to improve their anaerobic capacity. [less ▲]

Detailed reference viewed: 85 (5 ULg)
Full Text
Peer Reviewed
See detailEffect of sibutramine on cardiovascular outcomes in overweight and obese subjects.
James, W. P.; Caterson ID, I.D.; Coutinho, W. et al

in New England Journal of Medicine [=NEJM] (2010), 363

BACKGROUND: The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. METHODS: We ... [more ▼]

BACKGROUND: The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. METHODS: We enrolled in our study 10,744 overweight or obese subjects, 55 years of age or older, with preexisting cardiovascular disease, type 2 diabetes mellitus, or both to assess the cardiovascular consequences of weight management with and without sibutramine in subjects at high risk for cardiovascular events. All the subjects received sibutramine in addition to participating in a weight-management program during a 6-week, single-blind, lead-in period, after which 9804 subjects underwent random assignment in a double-blind fashion to sibutramine (4906 subjects) or placebo (4898 subjects). The primary end point was the time from randomization to the first occurrence of a primary outcome event (nonfatal myocardial infarction, nonfatal stroke, resuscitation after cardiac arrest, or cardiovascular death). RESULTS: The mean duration of treatment was 3.4 years. The mean weight loss during the lead-in period was 2.6 kg; after randomization, the subjects in the sibutramine group achieved and maintained further weight reduction (mean, 1.7 kg). The mean blood pressure decreased in both groups, with greater reductions in the placebo group than in the sibutramine group (mean difference, 1.2/1.4 mm Hg). The risk of a primary outcome event was 11.4% in the sibutramine group as compared with 10.0% in the placebo group (hazard ratio, 1.16; 95% confidence interval [CI], 1.03 to 1.31; P=0.02). The rates of nonfatal myocardial infarction and nonfatal stroke were 4.1% and 2.6% in the sibutramine group and 3.2% and 1.9% in the placebo group, respectively (hazard ratio for nonfatal myocardial infarction, 1.28; 95% CI, 1.04 to 1.57; P=0.02; hazard ratio for nonfatal stroke, 1.36; 95% CI, 1.04 to 1.77; P=0.03). The rates of cardiovascular death and death from any cause were not increased. CONCLUSIONS: Subjects with preexisting cardiovascular conditions who were receiving long-term sibutramine treatment had an increased risk of nonfatal myocardial infarction and nonfatal stroke but not of cardiovascular death or death from any cause. (Funded by Abbott; ClinicalTrials.gov number, NCT00234832.) [less ▲]

Detailed reference viewed: 23 (4 ULg)
See detailEffect of SIBX-PAX collector mixture Ore : Kansanshi (Zambia) - HG5
Bastin, David ULg; Kottgen, Axel

Report (2009)

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailEffect of silica-coated poly(butyl methacrylate)-block-poly(methyl methacrylate) double-shell particles on the mechanical properties of PMMA composites
Chakkalakal, G. L.; Alexandre, Michaël ULg; Boschetti-de-Fierro, Adriana et al

in Macromolecular Materials and Engineering (2012), 297(9), 887-893

Silica nanoparticles with average diameters of 12nm are grafted with PBMA-b-PMMA double shells through typical ATRP from a Si12-g-(PBMA)Br macroinitiator using 2-BriB as the initiator. A commercially ... [more ▼]

Silica nanoparticles with average diameters of 12nm are grafted with PBMA-b-PMMA double shells through typical ATRP from a Si12-g-(PBMA)Br macroinitiator using 2-BriB as the initiator. A commercially available PMMA homopolymer is used for the preparation of composites with unmodified, silane-modified and double-shell-modified silica particles. Good mechanical properties are obtained for silica double shell containing systems. The silica content in double shell particle systems is varied from 0 to 2.5 wt%. A significant improvement in impact properties is observed. The surface-modified silica particles are characterized by ATR-FTIR, NMR, GPC, and thermal analysis. TEM analysis is used to analyze the nature of dispersion of particles in the composites. [less ▲]

Detailed reference viewed: 65 (12 ULg)
Full Text
Peer Reviewed
See detailEffect of single annual infusion of zoledronic acid on bone turnover markers versus daily oral risedronate in patients with glucocorticoid-induced osteoporosis
Sambrook, P.; Reid, D.; Devogelaer, Jean-Pierre et al

in Osteoporosis International (2009, April), 20(Suppl.1), 128-129

Detailed reference viewed: 14 (4 ULg)
Full Text
Peer Reviewed
See detailThe effect of singletons and interval length on interpreting diversity trends from the palaeobotanical record
Cascales - Miñana, Borja ULg; Diez, José B.

in Palaeontologia Electronica (2012), 15(1),

The reliability and the identification of potential biases are central aspects to providing an accurate robust palaeontological data analysis. In the last decade, older concepts of evolutionary processes ... [more ▼]

The reliability and the identification of potential biases are central aspects to providing an accurate robust palaeontological data analysis. In the last decade, older concepts of evolutionary processes and patterns have been revised in the light of new methods and hypotheses. Moreover, new mathematical algorithms have been developed to better interpret evolution and to reduce several biases inherent in the fossil record from the animal viewpoint. This new global study, based on a complete overview of the plant fossil record, uses comparisons with previously established palaeofloristic patterns and employs a set of regression, accumulative and evolutionary analyses to test the influence of two important variables in the inference methods: the role of singleton taxa and the duration of the time units. The regression analyses reveal that the duration of the time units employed does not distort our perception of the number of singletons at the family level. Likewise, the duration as single factor also does not affect the measures of taxonomic diversity, and does not influence representation of the main evolutionary patterns of vascular plants. The analysis reveals that the percapita origination and extinction rates used provide global diversity patterns that diminish the effects of the possible taxonomic problems and preservational biases relating to the controversial nature of singleton taxa due to its restricted record, and they reveal that the main trends and plant turnover is characterized by slight abrupt changes, thus providing a more realistic vision about the dimension and magnitude of the observed evolutionary processes and diversification patterns from the plant fossil record. © Palaeontological Association January 2012. [less ▲]

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailEffect Of Site Location And Collecting Period On The Chemical Composition Of Hyptis Spicigera Lam. An Insecticidal Essential Oil From North-Cameroon
Noudjou, Félicité; Kouninki, Habiba; Ngamo, Léonard S.T. et al

in Journal of Essential Oil Research (2007), 19(6), 597-601

Detailed reference viewed: 67 (8 ULg)
Full Text
Peer Reviewed
See detailThe effect of size, weight, body compartment, sex and reproductive status on the bioaccumulation of 19 trace elements in rope-grown Mytilus galloprovincialis
Richir, Jonathan ULg; Gobert, Sylvie ULg

in Ecological Indicators (2014), 36

Numerous trace elements (TEs) can be considered as potential pollutants of the environment, their mining productions and industrial uses increasing worldwide. Their monitoring can be achieved through the ... [more ▼]

Numerous trace elements (TEs) can be considered as potential pollutants of the environment, their mining productions and industrial uses increasing worldwide. Their monitoring can be achieved through the use of bioindicator species, such as the Mediterranean mussel Mytilus galloprovincialis (Lamarck, 1819). That species has been widely used to monitor the chemical pollution of coastal ecosystems by Cr, Ni, Cu, Zn, Cd, Pb, As, Ag and V. Conversely, environmental levels of Be, Al, Fe, Mn, Co, Se, Mo, Sn, Sb and Bi have been little or not monitored so far in mussel watch programs. Bioaccumulation processes of these 19 TEs in rope-grown M. galloprovincialis purchased from a salt pond with good chemical water quality were thus investigated in the present study. Mussels efficiently accumulated the 19 studied TEs. Bioaccumulation processes were driven by numerous mutually dependent biological parameters such as the mussel size and flesh weight, the sex and the reproductive status and the body compartment considered. TE bioaccumulation was a power function of the mussel soft body dry weight; total contents linearly increased with the shell length. Small-size mussels overall concentrated more TEs, with a high inter-individual variability, consequently influencing the modelling of their bioaccumulation in the whole rope population. Although a large range of rope-grown M. galloprovincialis sizes can be used for monitoring purposes, one will thus take care not to use extreme size individuals. The influence of gametogenesis in determining female body higher TE concentrations prior to spawning could not be neglected and varied depending on the element. TEs were preferentially accumulated in the hepatopancreas, except for Zn, Se, Cd and Mo, more concentrated in gills. Gametogenesis did not influence TE distribution between body compartments, but likely diluted their concentrations as a direct consequence of massive reproductive tissue production. So, results from the present study underline the potential use of M. galloprovincialis in the biomonitoring of numerous little studied TEs and give some insights into the decisive role played by some relevant biological parameters in bioaccumulation processes of the 19 investigated TEs in rope-grown mussels. [less ▲]

Detailed reference viewed: 99 (32 ULg)
Peer Reviewed
See detailEffect of SK channel blockade on the firing of dorsal raphe neurons in anaesthetized rats
Alleva, Livia ULg; Rouchet, Nathalie; Waroux, Olivier ULg et al

Poster (2006, October 17)

K channels are small conductance calcium-activated potassium channels which trigger an outward current generating an afterhyperpolarization (AHP). This AHP follows a single or a train of action potential ... [more ▼]

K channels are small conductance calcium-activated potassium channels which trigger an outward current generating an afterhyperpolarization (AHP). This AHP follows a single or a train of action potential, and therefore is important in the regulation of the firing frequency and/or pattern of many types of neurons. Serotonergic (5-HT) neurons from the raphe nuclei express SK channels and exhibit a significant AHP which can be efficiently blocked in vitro by apamin and N-methyl laudanosine (NML) (Scuvée-Moreau et al, 2004). In the later study, we found that some but not all neurons (50%) had a significantly increase in their firing rate when positive current was injected after SK channel blockade. In order to determine the physiological relevance of these channels in vivo, single unit extracellular recordings were carried out in anesthetized rats and combined with iontophoresis of the specific non-peptidic SK channel blocker, UCL1684. 5-HT neurons were tested for their inhibitory response to locally applied 5-HT and histological analysis confirmed the localization of the recording site. UCL 1684 was used at a concentration of 200 µM. Out of 11 neurons recorded, 6 showed a significant increase in the production of doublets, with no effect on their mean firing rate as compared to the control condition. The other neurons were completely unaffected. These results suggest that the responsiveness of presumed 5-HT neurons to SK channel block is variable. Although the use of 200 µM UCL allow us to be sure of a sufficient SK blockade at the recording site (Waroux et al, 2005), we can not rule out the possibility that SK channels present at the dendritic level were not completely blocked. In conclusion, SK channels in vivo might play a role in controlling the firing pattern of a subgroup of 5-HT neurons. [less ▲]

Detailed reference viewed: 26 (2 ULg)
Full Text
Peer Reviewed
See detailThe effect of social security on saving: the case of Belgium with a particular emphasis on the behaviour of the aged
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Empirical Economics (1984), (9), 15-26

Based on a consumer expenditure function estimated with Belgian time series data, this paper analyses the impact of social security on personal saving. It shows that social security has a depressive ... [more ▼]

Based on a consumer expenditure function estimated with Belgian time series data, this paper analyses the impact of social security on personal saving. It shows that social security has a depressive effect, mainly by affecting the saving behavior of the aged. [less ▲]

Detailed reference viewed: 12 (4 ULg)
Full Text
Peer Reviewed
See detailThe Effect of Sodium Monofluorophosphate Plus Calcium on Vertebral Fracture Rate in Postmenopausal Women with Moderate Osteoporosis. A Randomized, Controlled Trial
Reginster, Jean-Yves ULg; Meurmans, L.; Zegels, Brigitte ULg et al

in Annals of Internal Medicine (1998), 129(1), 1-8

BACKGROUND: Fluoride is effective in increasing trabecular bone mineral density (BMD) in the spine, but its efficacy in reducing vertebral fracture rates and its effect on BMD at cortical sites are ... [more ▼]

BACKGROUND: Fluoride is effective in increasing trabecular bone mineral density (BMD) in the spine, but its efficacy in reducing vertebral fracture rates and its effect on BMD at cortical sites are controversial. OBJECTIVE: To study the effect of low-dose fluoride (sodium monofluorophosphate [MFP]) plus a calcium supplement over 4 years on vertebral fractures and BMD at the lumbar spine and total hip in postmenopausal women with moderately low BMD of the spine. DESIGN: Randomized, double-blind, controlled clinical trial. SETTING: Outpatient clinic for osteoporosis at a university medical center. PATIENTS: 200 postmenopausal women with osteoporosis (according to the World Health Organization definition) and a T-score less than -2.5 for BMD of the spine. INTERVENTION: Women were randomly assigned (100 patients per group) to continuous daily treatment for 4 years with 1) oral MFP (20 mg of equivalent fluoride) plus 1000 mg of calcium (as calcium carbonate) or 2) calcium only. MEASUREMENTS: Lateral spine radiographs were taken at enrollment and at each year of follow-up for detection of new vertebral fractures (defined as a reduction > or =20% and > or =4 mm from baseline in any of the heights of a vertebral body). Nonvertebral fractures were also recorded. All analyses were done with the intention-to-treat approach. RESULTS: Radiologic follow-up was possible for 164 of 200 patients (82%). The rate of new vertebral fractures during the 4 years of the study was lower in the MFP-plus-calcium group (2 of 84 patients; 2.4% [95% CI, 0.3% to 8.3%]) than in the calcium-only group (8 of 80 patients; 10% [CI, 4.4% to 18.8%]). The difference between the groups was 7.6 percentage points (CI, 0.3 to 15 percentage points) (P = 0.05). A moderate but progressive increase in BMD of the spine (10.0% +/- 1.5% at 4 years) was found for MFP plus calcium compared with calcium only (P < 0.001), whereas the more modest increase in BMD of the total hip seen with MFP plus calcium (1.8% +/- 0.6%) did not differ from the increase seen with calcium only. CONCLUSIONS: Low-dose fluoride (20 mg/d) given continuously with calcium for prolonged periods can decrease vertebral fracture rates compared with calcium alone in patients with mild to moderate osteoporosis. [less ▲]

Detailed reference viewed: 13 (4 ULg)
Full Text
Peer Reviewed
See detailEffect of sodium nitroprusside on complement activation induced by cardiopulmonary bypass: A clinical and experimental study
Seghaye, Marie-Christine ULg; Duchateau, J.; Grabitz, R. G. et al

in Journal of Thoracic and Cardiovascular Surgery (1996), 111(4), 882-892

Complement activation and leukocyte stimulation were prospectively studied during and after cardiopulmonary bypass in 16 children receiving sodium nitroprusside-a nitrovasodilator releasing nitric oxide ... [more ▼]

Complement activation and leukocyte stimulation were prospectively studied during and after cardiopulmonary bypass in 16 children receiving sodium nitroprusside-a nitrovasodilator releasing nitric oxide-for vasodilation during the cooling and rewarming periods of extracorporeal circulation. Results were compared with those in 29 patients who were not treated with sodium nitroprusside during the operation. Patients treated with sodium nitroprusside had significantly less C3 conversion during cardiopulmonary bypass as measured by the ratio C3d/C3 (p < 0.05) and significantly less C5a liberation immediately after cardiopulmonary bypass (p < 0.005) than patients not treated with sodium nitroprusside. C4 was not overtly consumed in our series. Leukocyte count during the rewarming period of cardiopulmonary bypass, but not leukocyte elastase release during cardiopulmonary bypass, was significantly reduced in patients treated with sodium nitroprusside (p < 0.05). In vitro experiments were conducted to analyze the effect of sodium nitroprusside on complement hemolytic activity initiated by the classic and the alternate pathways and on zymosan-induced C3 conversion by the activation of the alternate pathway. The in vitro experiments clearly demonstrate inhibition of complement hemolytic activity by sodium nitroprusside in the sera tested. The 50% inhibitory concentration of sodium nitroprusside on the available complement hemolytic activity was less through the alternate pathway than through the classic one (4.2 ± 0.8 mmol/L and 14.0 ± 2.88 mmol/L, respectively). The decrease of complement hemolytic activity measured was dose-dependent and was enhanced by the sodium nitroprusside preincubation of the sera tested. This effect was related to the duration of preincubation. Sodium nitroprusside photodegradation (enhancing nitric oxide release) increased the anticomplementary effect of the drug, reducing the 50% inhibitory concentration on complement hemolytic activity to 0.24 to 0.02 mmol/L for the alternate pathway and 2.74 o 0.3 mmol/L for the classic pathway. The zymosan-induced C3 conversion was inhibited by sodium nitroprusside. Nitroglycerin and isosorbide dinitrate (other nitric oxide donors) had in vitro effects on complement hemolytic activity similar to those of nonphotodegraded sodium nitroprusside at similar concentrations (1 mmol/L). Our results suggest that sodium nitroprusside, both in vitro and in vivo, has an inhibiting effect on complement activation initiated by both classic and alternate pathways and that this effect is mediated by nitric oxide release from sodium nitroprusside. This is the first report on the anticomplementary effect of sodium nitroprusside by nitric oxide release. [less ▲]

Detailed reference viewed: 4 (0 ULg)
See detailEffect of soft sulfidization Ore : Kansanshi (Zambia) : HG5
Bastin, David ULg; Kottgen, Axel

Report (2009)

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailEffect of somatic growth on pulmonary function values in healthy Friesian cattle
Lekeux, Pierre ULg; Hajer, R.; Breukink, H. J.

in American Journal of Veterinary Research (1984), 45(10), 2003-2007

Growth-related changes in pulmonary function values (PFV) of cattle were investigated by a cross-sectional study of 40 healthy Dutch Friesian cattle, 3 days to 13 years of age and weighing 37 to 660 kg ... [more ▼]

Growth-related changes in pulmonary function values (PFV) of cattle were investigated by a cross-sectional study of 40 healthy Dutch Friesian cattle, 3 days to 13 years of age and weighing 37 to 660 kg. Technical and methodologic procedures and body conformation and condition were standardized. A regression analysis was done with 4 independent variables (body weight, thoracic perimeter, body surface area, and age) and with PFV measured in this study. Ventilation values, dynamic lung compliance, and viscous work of breathing changed linearly with somatic growth. Respiratory frequency, total pulmonary resistance, and arterial oxygen tension showed an exponential relationship with all the independent variables. On the other hand, intrapleural pressure values were weakly correlated with body size indexes. The most important growth-related changes in PFV occurred at approximately 1 year of age. A significant (P less than or equal to 0.05) difference between immature and mature cattle was shown for the blood-gas values and the specific values of the breathing mechanics. The dynamic lung compliance/lung weight was lower and the total pulmonary resistance X minute volume was higher in cattle than in other domestic mammals. The regression equation, giving the best fit of the data, was selected for each PFV. [less ▲]

Detailed reference viewed: 9 (1 ULg)