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See detailDermatologic Manifestations of the LEOPARD Syndrome
CAO, Sandrine ULiege; NIKKELS, Arjen ULiege

in The Open Dermatology Journal (2013), 7

The LEOPARD syndrome is an exceptional autosomal dominant genetic disease with a missence mutation of the PTPN11 gene in more than 90% of the cases. The principal clinical manifestations include extensive ... [more ▼]

The LEOPARD syndrome is an exceptional autosomal dominant genetic disease with a missence mutation of the PTPN11 gene in more than 90% of the cases. The principal clinical manifestations include extensive lentiginosis, heart conduction abnormalities, hypertrophic obstructive cardiomyopathy, ocular hypertelorism, pulmonary stenosis, genital anomalies, mental retardation, growth retardation and deafness. A woman with a LEOPARD syndrome illustrates the progressive development of melanocytic nevi. In fact, the majority of lentigines are actually melanocytic nevi. Seqential digital demroscopy evidences progressive growth of some melanocytic lesions. The ever-increasing number of melanocytic nevi in the LEOPARD syndrome is a risk factor for melanoma and full body photography and dermoscopy are recommended for follow-up. [less ▲]

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See detailDermatological manifestations of varicella
EL HAYDERI, Lara ULiege; NIKKELS, Arjen ULiege

in Berhardt, Leon V. (Ed.) Advances in Medicine and Biology (2013)

The Varicella zoster virus (VZV) is responsible for chickenpox and herpes zoster (HZ). VZV displays neuro- and epidermotropism, although other cells lines may be infected. A permissive type of VZV ... [more ▼]

The Varicella zoster virus (VZV) is responsible for chickenpox and herpes zoster (HZ). VZV displays neuro- and epidermotropism, although other cells lines may be infected. A permissive type of VZV infection in the epidermal and/or infundibular keratinocytes forms the majority of the skin lesions. This infections leads to intra-epidermal blistering, clinically characterized by vesicular lesions. During varicella, the haematogenous dissemination of VZV virions infects the dermal endothelial cells, which in their turn infect dermal dendrocytes who transport he virions to the keratinocytes of the basal layer. During HZ, the VZV virions arrive in the keratinocytes after release by the free nerve endings in close contact with the basal keratinocytes. The skin-associated immune system (SALT) furthermore determines the outcome of the virus/host cell relation. The spectrum of the VZV-related skin infections is presented with their pathogenic mechanisms, including lichenoid HZ, granulomatous HZ, verrucous HZ and follicular HZ. It is important to be aware of these manifestations of the VZV, in particular as VZV may present serious morbidity int eh immunocompromised patient. [less ▲]

Detailed reference viewed: 103 (3 ULiège)
See detailDermatologie et Rhumatologie.
Quatresooz, Pascale ULiege

Scientific conference (2007)

Detailed reference viewed: 19 (1 ULiège)
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See detailLes dermatomycoses de l'estran.
CAUCANAS, Marie ULiege; FRANCHIMONT, Claudine ULiege; PIERARD, Gérald ULiege

in Dermatologie Actualité (2011), 127

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See detailDermatophylose équine: revue à partir d'un cas clinique
Vandenput, Sandrina ULiege; Manteca, C.; Jauniaux, Thierry ULiege et al

in Annales de Médecine Vétérinaire (1996), 140(2), 125-129

From a clinical case of equine dermatophilosis, a short review of literature is proposed. The aetiology, causal factors, symptoms and lesions are brievely reviewed. Therapeutics and prophylaxis are ... [more ▼]

From a clinical case of equine dermatophilosis, a short review of literature is proposed. The aetiology, causal factors, symptoms and lesions are brievely reviewed. Therapeutics and prophylaxis are outlined. [less ▲]

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See detailThe dermatophyte species Arthroderma benhamiae: intraspecies variability and mating behaviour
Symoens, F; Jousson, O; Packeu, A et al

in Journal of Medical Microbiology (2013), 62

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See detailDermatophytes and Dermatophytoses
Vishnu, Chaturvedi; Boucharat, Jean-Philippe; Mignon, Bernard ULiege

in Mycopathologia (2017), 182(1-2), 1-31

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See detailDermatophytes and Dermatophytoses
Chaturvedi, Vishnu; Bouchara, Jean-Philippe; Mignon, Bernard ULiege

in Mycopathologia (2008), 166(5-6), 235-424

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See detailDermatophytes and Dermatophytoses: A Thematic Overview of State of the Art, and the Directions for Future Research and Developments
Bouchara, JP; Mignon, Bernard ULiege; Chaturvedi, V

in Mycopathologia (2017), 182(1), 1-4

Detailed reference viewed: 37 (6 ULiège)
See detailDermatophytes as Saprophytes and Pathogens
Monod, M; Mignon, Bernard ULiege; Staib, P

in Sullivan, DJ; Moran, GP (Eds.) Human Pathogenic Fungi: Molecular Biology and Pathogenic Mechanisms (2014)

Dermatophytes infect the stratum corneum, nails and hair and are the most common agents of superficial mycoses in humans and animals. At present the genome of seven species has been sequenced. Between 22 ... [more ▼]

Dermatophytes infect the stratum corneum, nails and hair and are the most common agents of superficial mycoses in humans and animals. At present the genome of seven species has been sequenced. Between 22.5 and 24 Mb, the dermatophyte genomes are smaller in size than those of Coccidioides spp., Histoplasma spp. and Aspergillus spp. They are enriched for particular families of genes encoding secreted proteases, fungal specific kinases and proteins containing the LysM domain that is known to bind chitin. Different tools were recently developed to improve genetic analyses of dermatophytes, including efficient systems for targeted gene inactivation, gene silencing and broad transcriptional profiling techniques. Unexpectedly, gene expression profiles in the skin and hair of infected guinea pigs were found to be very different from those during in vitro growth using hard keratin as a substrate. Instead of the major in vitro expressed protease genes, others were found to only be activated in the skin of infected animals. In other words, the expression of putative virulence genes in dermatophytoses is more complex than previously assumed and likely depends on the site and type of infection. Further broad transcriptional profiling approaches during infections will give new insights into the pathogenic mechanisms of dermatophytes. [less ▲]

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See detailDermatophytes transmis par les animaux domestiques
Monod, M; Fratti, B; Mignon, Bernard ULiege et al

in Revue Médicale Suisse (2014), 10

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See detailDermatophyties
Mignon, Bernard ULiege

in Guaguère E., Prélaud P. (Ed.) Guide pratique de dermatologie canine (2006)

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See detailDermatophytoses - Mise au point
Mignon, Bernard ULiege

Conference given outside the academic context (2004)

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See detailDermatophytoses : actualités épidémiologiques et diagnostiques
Mignon, Bernard ULiege

in Pratique Vet (2010), 45

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See detailDermatophytosis in cats : ABCD guidelines on prevention and management
Frymus; Gruffydd-Jones, T.; Pennisi, M.G. et al

in Journal of Feline Medicine and Surgery (2013), 15

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See detailDermatophytosis, Trends in Epidemiolgy and Diagnostic Approach
HAYETTE, Marie-Pierre ULiege; SACHELI, Rosalie ULiege

in Current Fungal Infections report (2015), 9(3), 164-179

Dermatophytes are among the common fungal agents implicated in superficial skin infections. The anthropophilic dermatophyte Trichophyton rubrum is still the most frequent causative agent worldwide but the ... [more ▼]

Dermatophytes are among the common fungal agents implicated in superficial skin infections. The anthropophilic dermatophyte Trichophyton rubrum is still the most frequent causative agent worldwide but the prevalence of several species of dermatophytes varies through different areas around the world. This review summarizes the current status of dermatophytes infection in Europe, Africa, Asia and America and gives an overview of the molecular biology laboratory methods currently available for the diagnosis of dermatomycoses. [less ▲]

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See detailDermatophytosis: efficacy of commercial vaccines?
Mignon, Bernard ULiege

in Proceedings of the 5th World Congress of Veterinary Dermatology (2004)

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See detailLa dermatoporose, un "vintage" de l'atrophodermie et de la "peau transparente".
FRANCHIMONT, Claudine ULiege; Hermanns, J.F.; Hermanns-Lê, Trinh ULiege et al

in Revue Médicale de Liège (2014), 69

Le vieillissement de la peau se marque à terme par une atrophodermie, parfois sévère. La corticothérapie, qu’elle soit systémique ou topique, exerce un effet atrophiant qui copie l’effet du grand âge. Cet ... [more ▼]

Le vieillissement de la peau se marque à terme par une atrophodermie, parfois sévère. La corticothérapie, qu’elle soit systémique ou topique, exerce un effet atrophiant qui copie l’effet du grand âge. Cet état d’atrophodermie a été décrit comme la «peau transparente» il y a une quarantaine d’années, et il a reçu plus récemment la nouvelle dénomination de dermatoporose. Il est connu de longue date que cet état entraîne des conséquences cliniques parfois majeures qui conduisent à des lésions diverses sous forme de purpura de Bateman, de cicatrices stellaires, et de plaies faisant suite à des traumatismes mineurs. [less ▲]

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See detailLes dermatoses les plus fréquentes chez le chiot
Mignon, Bernard ULiege

Conference given outside the academic context (2005)

Detailed reference viewed: 18 (2 ULiège)