Le Dévonien du sondage de Nieuwkerke (Flandre occidentale, Belgique, extrémité occidentale du Synclinorium de Namur)
; ; et al
in Annales de la Société Géologique du Nord (1989), CVIIIDetailed reference viewed: 23 (1 ULg)
La dévotion à travers le culte des reliques de saints. Dossier pédagogique - Trésor de la Cathédrale de Liège
Learning material (2013)
Situé en plein centre ville, le Trésor de Liège est un musée d’art et d’histoire de l’ancienne principauté épiscopale de Liège. De taille humaine et bien agencé, il propose un parcours thématique idéal ... [more ▼]
Situé en plein centre ville, le Trésor de Liège est un musée d’art et d’histoire de l’ancienne principauté épiscopale de Liège. De taille humaine et bien agencé, il propose un parcours thématique idéal pour une sortie scolaire. Il permet la découverte d’œuvres d’art majeures du patrimoine artistique liégeois tels que des orfèvreries, des ivoires, des sculptures, des peintures et une collection exceptionnelle de textiles médiévaux. Le Trésor de Liège conserve également de nombreuses reliques dont l’étude peut se révéler être d’un grand intérêt pour les élèves du secondaire. La thématique qui permet de traiter au mieux un aspect important de la vie religieuse au Moyen Âge et aux Temps Modernes en abordant la chrétienté médiévale, de l’activité dévotionnelle, des mentalités ainsi que celle des croyances religieuses est celle du culte des reliques de saints. La question est de savoir comment intégrer ces thématiques à la matière vue en classe ? L’objectif de ce dossier est d’intégrer une visite du Trésor à l’exploitation de cette thématique. Les documents repris ci-dessous traitent essentiellement des saints de l’ancien diocèse de Liège qui couvrait la majeure partie du pays au Moyen Âge et aux Temps Modernes. L’usage d’exemples locaux se verra efficace puisqu’il suscitera l’intérêt des élèves. La visite des collections du Trésor s’adresse principalement aux élèves de 4e année de l’enseignement libre ainsi qu’aux élèves de 3e année de l’enseignement officiel. Cette visite permet ainsi à ces deux réseaux d’étudier un outil conceptuel, « les rapports entre religion et société civile », tel que mentionné dans le Référentiel inter-réseaux. Ce dossier se veut complet. Il fournit des outils ainsi que des pistes de travail aux enseignants afin que ces derniers les utilisent en classe avant ou après une visite du Trésor. Il se compose de documents, d’analyses de documents, d’analyses d’œuvres d’art du musée, de fiches de travail pour les élèves, de démarches pédagogiques pour les enseignants ainsi que d’une orientation bibliographique. Ce dossier a pour but d’inciter les enseignants à venir visiter le Trésor afin de découvrir la richesse de ses collections. La visite est donc essentielle pour tirer profit au maximum des fiches de travail destinées aux élèves. Ces derniers auront ainsi un contact direct avec les reliquaires et pourront plus facilement les observer et les analyser dans un cadre muséal qui les conserve et les expose au public. [less ▲]Detailed reference viewed: 79 (11 ULg)
La dévotion mariale, facteur d’identification dans les Pays-Bas espagnols
in Cottret, M.; Belissa, M.; Belavitis, A. (Eds.) Identités, appartenances, revendications identitaires (XVIe-XVIIIe siècle) (2005)
The author studies the use of the Marian worship as an identitary factor in the Catholic Low Countries (end 16th- 17th c.). She shows how, in a stormy military context, this symbolical character served as ... [more ▼]
The author studies the use of the Marian worship as an identitary factor in the Catholic Low Countries (end 16th- 17th c.). She shows how, in a stormy military context, this symbolical character served as a principle of fusion, favouring the unity of the group and carrying therefore the individual to conform himself with common values i.e. fidelity to the reformed Catholicism and loyalty to the Habsburg authority. [less ▲]Detailed reference viewed: 107 (14 ULg)
Devotional Portraits of Guilds and Confraternities in Early Netherlandish Painting: Between Cohesion of Identity and Expression of Religiosity
Conference (2011, April 26)Detailed reference viewed: 20 (0 ULg)
Dévotions du pays de Liège d’après le chanteur de rue Joseph Mousset dit Hasserz (1799-1870)
in Tamine, Michel (Ed.) Dévotions populaires. Actes du Colloque (2008)Detailed reference viewed: 65 (10 ULg)
Dew point effect of cooled hydrogel pads on human stratum corneum biosurface.
Xhauflaire, Emmanuelle ; Paquet, Philippe ; Pierard, Gérald
in Dermatology : International Journal for Clinical & Investigative Dermatology (2008), 216(1), 37-9
BACKGROUND: Cooled hydrogel pads are used to prevent overheating effects of laser therapy. They do not induce cold injuries to the skin, but their more subtle physiological effects have not been ... [more ▼]
BACKGROUND: Cooled hydrogel pads are used to prevent overheating effects of laser therapy. They do not induce cold injuries to the skin, but their more subtle physiological effects have not been thoroughly studied. PURPOSE: To describe the changes in transepidermal water loss and electrometric properties of the skin surface following application of cooled hydrogel pads. Measurements were performed on normal forearm skin of 27 healthy volunteers and on freshly excised skin from abdominoplasty. METHODS: LaserAid hydrogel pads cooled to 4 degrees C were placed for 15 min on the forearm skin. Measurements of transepidermal water loss (TEWL) and electrometric properties (Corneometer, Nova DPM 900) were performed before application and after removal of the cooled pads. RESULTS: A consistent increase in corneometer units, dermal phase meter (DPM) values and TEWL were recorded at removal of the cooled hydrogel pads. Both the in vivo and in vitro assessments brought similar information. DISCUSSION: The similar changes disclosed in vitro and in vivo suggest that a common physical process is operating in these conditions. The observed phenomenon is opposite to the predicted events given by the Arrhenius law probably because of the combination of cooling and occlusion by the pads. A dew point effect (air temperature at which relative humidity is maximal) is likely involved in the moisture content of the stratum corneum. Thus, the biological impact of using cooling hydrogel pads during laser therapy is different from the effect of a cryogenic spray cooling procedure. The better preservation of the water balance in the stratum corneum by the cooled hydrogel pads could have a beneficial esthetic effect on laser treated areas. [less ▲]Detailed reference viewed: 40 (2 ULg)
Dexamethasone Bovine Pharmacokinetics
; Lognay, Georges ; et al
in European Journal of Drug Metabolism and Pharmacokinetics (1991), 16(3), 219-221
Dexamethasone phosphate (DXM-PHO) is an ester which is quickly hydrolysed by the bovine and the dexamethasone (DXM) plasma half-life was 5.16 h. It has been demonstrated that 54 h after DXM-PHO injection ... [more ▼]
Dexamethasone phosphate (DXM-PHO) is an ester which is quickly hydrolysed by the bovine and the dexamethasone (DXM) plasma half-life was 5.16 h. It has been demonstrated that 54 h after DXM-PHO injection, DXM concentrations were lower than 0.1 mglml. Tritiated dexamethasone was also administered twice to an another young bull for metabolite investigation. The elapsed time required to recover, in plasma, half of the radioactivity injected was 8.8 h. Radioactivity recovery in the urine reached 36.4% and 22.6% for the first and the second injections respectively. [less ▲]Detailed reference viewed: 25 (0 ULg)
Dexamethasone compared to prednisolone for adults with acute lymphoblastic leukemia or lymphoblastic lymphoma : final results of the ALL-4 randomized, phase III trial of the EORTC Leukemia Group
; ; et al
in Haematologica (2010), 95Detailed reference viewed: 8 (1 ULg)
Dexamethasone Ester Treatment Alters Insulin-Like Growth Factor-I, Its Binding Proteins And Thyroid Status In Finishing Calves
; Portetelle, Daniel ; et al
in Canadian Journal of Animal Science (2000), 80(2),Detailed reference viewed: 24 (5 ULg)
Dexamethasone in childhood ALL : split versus continuous - What's best for bones. A review.
Geurten, Claire ; Piette, Caroline ; Hoyoux, Claire
Conference (2015, October 22)Detailed reference viewed: 17 (0 ULg)
Dexamethasone inhibits the HSV-tk/ ganciclovir bystander effect in malignant glioma cells.
Robe, Pierre ; Nguyen-Khac, Minh-Tuan ; Jolois, Olivier et al
in BMC Cancer (2005), 5
BACKGROUND: HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. Large studies have however failed to demonstrate ... [more ▼]
BACKGROUND: HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. Large studies have however failed to demonstrate any significant benefit of this strategy in the treatment of human brain tumors. Since dexamethasone is a frequently used symptomatic treatment for malignant gliomas, its interaction with the bystander effect and the overall efficacy of HSV-TK gene therapy ought to be assessed. METHODS: Stable clones of TK-expressing U87, C6 and LN18 cells were generated and their bystander effect on wild type cells was assessed. The effects of dexamethasone on cell proliferation and sensitivity to ganciclovir were assessed with a thymidine incorporation assay and a MTT test. Gap junction mediated intercellular communication was assessed with microinjections and FACS analysis of calcein transfer. The effect of dexamethasone treatment on the sensitivity of TK-expressing to FAS-dependent apoptosis in the presence or absence of ganciclovir was assessed with an MTT test. Western blot was used to evidence the effect of dexamethasone on the expression of Cx43, CD95, CIAP2 and BclXL. RESULTS: Dexamethasone significantly reduced the bystander effect in TK-expressing C6, LN18 and U87 cells. This inhibition results from a reduction of the gap junction mediated intercellular communication of these cells (GJIC), from an inhibition of their growth and thymidine incorporation and from a modulation of the apoptotic cascade. CONCLUSION: The overall efficacy of HSV-TK gene therapy is adversely affected by dexamethasone co-treatment in vitro. Future HSV-tk/ GCV gene therapy clinical protocols for gliomas should address this interference of corticosteroid treatment. [less ▲]Detailed reference viewed: 41 (4 ULg)
Dexamethasone pretreatment provides antiinflammatory and myocardial protection in neonatal arterial switch operation.
; ; SCHUMACHER, Katharina et al
in Annals of Thoracic Surgery (2012), 93(3), 869-76
BACKGROUND: This prospective double-blinded randomized study tested the hypothesis that preoperative treatment with dexamethasone would attenuate inflammatory priming of the myocardium, reduce the ... [more ▼]
BACKGROUND: This prospective double-blinded randomized study tested the hypothesis that preoperative treatment with dexamethasone would attenuate inflammatory priming of the myocardium, reduce the systemic inflammatory reaction upon cardiac operation, and provide organ protection in neonates. METHODS: Twenty neonates (age, 8 to 21 days) with transposition of the great arteries scheduled for arterial switch operation were included. Nine received dexamethasone (1 mg/kg body weight) 4 hours before cardiopulmonary bypass, and 11 received natrium chloride. We studied intramyocardial messenger RNA expression of interleukin (IL)-6, IL-8, IL-1beta, and tumor necrosis factor-alpha (TNF-alpha), as well as IL-10 and expression of TNF-alpha on protein level in right atrial tissue taken before institution of CPB. We measured plasma levels of IL-6, IL-10, lipopolysaccharide binding protein, and cardiac troponin T. Cytokine expression was related to postoperative outcome. RESULTS: Pretreatment with dexamethasone led to a significant decrease in myocardial expression of IL-6, IL-8, IL-1beta, and TNF-alpha messenger RNA and to a decrease in protein synthesis of TNF-alpha. Plasma concentrations of IL-6 were significantly lower and those of IL-10 significantly higher in pretreated patients. This was associated with lower cardiac troponin T values and lower dobutamine requirement. Levels of lipopolysaccharide binding protein were significantly higher postoperatively in pretreated neonates. CONCLUSIONS: Dexamethasone administration before arterial switch operation leads to a shift in the myocardial and systemic cytokine expression profile in neonates with transposition of the great arteries, with downregulation of proinflammatory and upregulation of antiinflammatory cytokines. Lower myocardial cell damage and lower catecholamine requirement suggest myocardial protection in treated patients. [less ▲]Detailed reference viewed: 44 (12 ULg)
Dexamethasone suppression test and prediction of treatment response to selective antidepressants
ANSSEAU, Marc ; PAPART, Patrick ; PITCHOT, William et al
in European Psychiatry (1992)Detailed reference viewed: 11 (1 ULg)
The dexamethasone suppression test in violent suicide attempters with major depression.
Pitchot, William ; Hansenne, Michel ; et al
in Biological Psychiatry (1995), 37(4), 273-4Detailed reference viewed: 12 (0 ULg)
Dexamethasone-induced accumulation of a fibronectin and collagen extracellular matrix in transformed human cells.
; ; et al
in Nature (1979), 277(5695), 393-5Detailed reference viewed: 5 (0 ULg)
The dexamethasone-induced inhibition of proliferation, migration and invasion in glioma cell lines is antagonized by macrophage migration inhibitory factor (MIF) and can be enhanced by specific MIF inhibitors.
Piette, Caroline ; Deprez, Manuel ; et al
in Journal of Biological Chemistry (2009), 284(47), 32483-92
Glioblastomas (GBMs) are the most frequent and malignant brain tumors in adults. Glucocorticoids (GCs) are routinely used in the treatment of GBMs for their capacity to reduce the tumor-associated edema ... [more ▼]
Glioblastomas (GBMs) are the most frequent and malignant brain tumors in adults. Glucocorticoids (GCs) are routinely used in the treatment of GBMs for their capacity to reduce the tumor-associated edema. Few in vitro studies have suggested that GCs inhibit the migration and invasion of GBM cells through the induction of MAPK phosphatase 1 (MKP-1). Macrophage migration inhibitory factor (MIF), an endogenous GC antagonist is up-regulated in GBMs. Recently, MIF has been involved in tumor growth and migration/invasion and specific MIF inhibitors have been developed on their capacity to block its enzymatic tautomerase activity site. In this study, we characterized several glioma cell lines for their MIF production. U373 MG cells were selected for their very low endogenous levels of MIF. We showed that dexamethasone inhibits the migration and invasion of U373 MG cells, through a glucocorticoid receptor (GR)- dependent inhibition of the ERK1/2 MAPK pathway. Oppositely, we found that exogenous MIF increases U373 MG migration and invasion through the stimulation of the ERK1/2 MAP kinase pathway and that this activation is CD74 independent. Finally, we used the Hs 683 glioma cells that are resistant to GCs and produce high levels of endogenous MIF, and showed that the specific MIF inhibitor ISO-1 could restore dexamethasone sensitivity in these cells. Collectively, our results indicate an intricate pathway between MIF expression and GC resistance. They suggest that MIF inhibitors could increase the response of GBMs to corticotherapy. [less ▲]Detailed reference viewed: 65 (9 ULg)