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See detailEfficient synthesis of 2,5-diketopiperazines by Staudinger-mediated cyclization
Beagle, Lucas; Hansen, Finn; Monbaliu, Jean-Christophe ULg et al

in Synlett (2012), 23(16), 2337-2340

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See detailEfficient targeted energy transfers in coupled nonlinear oscillators through 1:1 transcient resonance captures:
Sapsis, Themistoklis; Quinn, D. Dane; Gendelman, Oleg et al

in Sixth EUROMECH Nonlinear Dynamics Conference, Saint Petersbourg, 2008 (2008)

We study targeted energy transfer (TET) in a two degree-of-freedom damped system caused by 1:1 transient resonance capture (TRC). The system consists of a linear oscillator strongly coupled to an ... [more ▼]

We study targeted energy transfer (TET) in a two degree-of-freedom damped system caused by 1:1 transient resonance capture (TRC). The system consists of a linear oscillator strongly coupled to an essentially nonlinear attachment. First, we study the underlying structure of the Hamiltonian dynamics of the system, and then show that, for sufficiently small values of viscous damping, the nonlinear damped transitions are strongly influenced by the underlying topological structure of periodic and quasiperiodic orbits of the hamiltonian system. Then, a detailed computational study of the different types of nonlinear transitions that occur in the weakly damped system is presented. As a result of these studies, conditions that lead to effective or even optimal TET from the linear system to the nonlinear attachment are determined. Finally, direct analytical treatment of the governing strongly nonlinear damped equations of motion is performed through slow/fast partition of the transient responses, in order to analytically model the dynamics the region of optimal TET, and to determine the characteristic time scales of the dynamics that influence the capacity of the nonlinear attachment to passively absorb and locally dissipate broadband energy from the linear oscillator. [less ▲]

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See detailEfficient transformation and regeneration of transgenic cassava using the neomycin phosphotransferase gene as aminoglycoside resistance marker gene.
Niklaus, Michael; Gruissem, Wilhelm; Vanderschuren, Hervé ULg

in GM Crops (2011), 2(3), 193-200

Cassava is one of the most important crops in the tropics. Its industrial use for starch and biofuel production is also increasing its importance for agricultural production in tropical countries. In the ... [more ▼]

Cassava is one of the most important crops in the tropics. Its industrial use for starch and biofuel production is also increasing its importance for agricultural production in tropical countries. In the last decade cassava biotechnology has emerged as a valuable alternative to the breeding constraints of this highly heterozygous crop for improved trait development of cassava germplasm. Cassava transformation remains difficult and time-consuming because of limitations in selecting transgenic tissues and regeneration of transgenic plantlets. We have recently reported an efficient and robust cassava transformation protocol using the hygromycin phosphotransferase II (hptII) gene as selection marker and the aminoglycoside hygromycin at optimal concentrations to maximize the regeneration of transgenic plantlets. In the present work, we expanded the transformation protocol to the use of the neomycin phosphotransferase II (nptII) gene as selection marker. Several aminoglycosides compatible with the use of nptII were tested and optimal concentrations for cassava transformation were determined. Given its efficiency equivalent to hptII as selection marker with the described protocol, the use of nptII opens new possibilities to engineer transgenic cassava lines with multiple T-DNA insertions and to produce transgenic cassava with a resistance marker gene that is already deregulated in several commercial transgenic crops. [less ▲]

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See detailEfficient uncoupled stochastic analysis with non-proportional damping
Canor, Thomas ULg; Blaise, Nicolas ULg; Denoël, Vincent ULg

in Journal of Sound & Vibration (2012), 331(2012), 52835291

The use of normal modes of vibration in the analysis of structures with nonproportional damping reduces the size of the resulting set of governing equations, but does not decouple them. A common practice ... [more ▼]

The use of normal modes of vibration in the analysis of structures with nonproportional damping reduces the size of the resulting set of governing equations, but does not decouple them. A common practice consists in decoupling the equations by disregarding the o -diagonal elements in the modal damping matrix. Recently, an approximation based on an asymptotic expansion of the modal transfer matrix has been proposed in a deterministic framework to partially account for o -diagonal terms, but still with a set of uncoupled equations. This paper aims at extending this method in a stochastic context. First the mathematical background is introduced and the method is illustrated with a simple example. Then its relevance is demonstrated within the context of the structural analysis of a large and realistic structure. [less ▲]

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See detailEfficient Visualization of High-Order Finite Elements
Remacle, J.-F.; Chevaugeon, N.; Marchandise, E. et al

in International Journal for Numerical Methods in Engineering (2007), 69(4), 750--771

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See detailEfficiently approximating Markov tree bagging for high-dimensional density estimation
Schnitzler, François ULg; ammar, sourour; leray, philippe et al

in Gunopulos, Dimitrios; Hofmann, Thomas; Malerba, Donato (Eds.) et al Machine Learning and Knowledge Discovery in Databases, Part III (2011, September)

We consider algorithms for generating Mixtures of Bagged Markov Trees, for density estimation. In problems defined over many variables and when few observations are available, those mixtures generally ... [more ▼]

We consider algorithms for generating Mixtures of Bagged Markov Trees, for density estimation. In problems defined over many variables and when few observations are available, those mixtures generally outperform a single Markov tree maximizing the data likelihood, but are far more expensive to compute. In this paper, we describe new algorithms for approximating such models, with the aim of speeding up learning without sacrificing accuracy. More specifically, we propose to use a filtering step obtained as a by-product from computing a first Markov tree, so as to avoid considering poor candidate edges in the subsequently generated trees. We compare these algorithms (on synthetic data sets) to Mixtures of Bagged Markov Trees, as well as to a single Markov tree derived by the classical Chow-Liu algorithm and to a recently proposed randomized scheme used for building tree mixtures. [less ▲]

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See detailEfficiently Approximating Markov Tree Bagging for High-Dimensional Density Estimation
Schnitzler, François ULg

Scientific conference (2011, December 07)

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See detailEffondrement d’un mur de berge sur la Vesdre
Dewals, Benjamin ULg

in Interview on the Belgian radio RTBF (2010)

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See detailL'effondrement de la Générale des Carrières et des Mines.Chronique d'un processus de privatisation informelle
Rubbers, Benjamin ULg

in Cahiers d'Etudes Africaines (2006), 181

How this mining giant abruptly collapsed is the focus of this article. Instead of adopting what has become a classic interpretation-Mobutu's patrimonial politics and a poor economic environment, this work ... [more ▼]

How this mining giant abruptly collapsed is the focus of this article. Instead of adopting what has become a classic interpretation-Mobutu's patrimonial politics and a poor economic environment, this work underscores the internal dynamics of the company, in its particular social setting. [less ▲]

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See detailL'effort cognitif
Adam, Stéphane ULg

Conference (2007, April 11)

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See detailL'effort excentrique sur dynamomètre isocinétique
Croisier, Jean-Louis ULg; Crielaard, Jean-Michel ULg

in Actes de la 1ère Journée Belge d'Isocinétisme (1997, February)

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See detailEfforts électrodynamiques dans les postes à haute tension lors de défauts polyphasés.
Lilien, Jean-Louis ULg

in Hamza, M. H. (Ed.) Proceedings of the International Symposia on Energy and Technology. (1979, June)

Modélisation et calcul par éléments finis d'un jeu de barres rigides et d'un jeu de barres flexibles d'un psote à haute tension parcouru d-ar des intensités de courant de court-circuit

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See detailEfforts électrodynamiques dus aux courants de court-circuit dans les postes H.T.
Destoquay, Catherine; Géradin, Michel ULg; Lilien, Jean-Louis ULg

in Revue de l'association des ingénieurs sortis de Montefiore (1978), 3

Calcul par éléments finis des efforts mécaniques liés aux courants de court-circuit dans les postes à haute tension.

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See detailL'effraction critique. La littérature selon Léon Bloy
Durand, Pascal ULg

in Cahiers de l'Herne (1988)

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See detailEffusive-constructive pericarditis secondary to recurrent idiopathic pericardial effusion in a german shepherd dog
Motte; Hamaide, A.; Heimann, M. et al

in 11th ESVIM Meeting - Dublin - Irlande - 2001 (2001)

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See detailEFHC1 interacts with microtubules to regulate cell division and cortical development
de Nijs, Laurence ULg; Leon, Christine ULg; Nguyen, Laurent ULg et al

in Nature Neuroscience (2009), 12(10), 1266-74

Mutations in the EFHC1 gene are linked to juvenile myoclonic epilepsy (JME), one of the most frequent forms of idiopathic generalized epilepsies. JME is associated with subtle alterations of cortical and ... [more ▼]

Mutations in the EFHC1 gene are linked to juvenile myoclonic epilepsy (JME), one of the most frequent forms of idiopathic generalized epilepsies. JME is associated with subtle alterations of cortical and subcortical architecture, but the underlying pathological mechanism remains unknown. We found that EFHC1 is a microtubule-associated protein involved in the regulation of cell division. In vitro, EFHC1 loss of function disrupted mitotic spindle organization, impaired M phase progression, induced microtubule bundling and increased apoptosis. EFHC1 impairment in the rat developing neocortex by ex vivo and in utero electroporation caused a marked disruption of radial migration. We found that this effect was a result of cortical progenitors failing to exit the cell cycle and defects in the radial glia scaffold organization and in the locomotion of postmitotic neurons. Therefore, we propose that EFHC1 is a regulator of cell division and neuronal migration during cortical development and that disruption of its functions leads to JME [less ▲]

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See detailEFHC1, a protein mutated in juvenile myoclonic epilepsy, associates with the mitotic spindle through its N-terminus
de Nijs, Laurence ULg; Lakaye, Bernard ULg; Coumans, Bernard ULg et al

in Experimental Cell Research (2006), 312(15), 2872-2879

A novel gene, EFHC1, mutated in juvenile myoclonic epilepsy (JME) encodes a protein with three DM10 domains of unknown function and one putative EF-hand motif. To study the properties of EFHC1, we ... [more ▼]

A novel gene, EFHC1, mutated in juvenile myoclonic epilepsy (JME) encodes a protein with three DM10 domains of unknown function and one putative EF-hand motif. To study the properties of EFHC1, we expressed EGFP-tagged protein in various cell lines. In interphase cells, the fusion protein was present in the cytoplasm and in the nucleus with specific accumulation at the centrosome. During mitosis EGFP-EFHC1 colocalized with the mitotic spindle, especially at spindle poles and with the midbody during cytokinesis. Using a specific antibody, we demonstrated the same distribution of the endogenous protein. Deletion analyses revealed that the N-terminal region of EFHC1 is crucial for the association with the mitotic spindle and the midbody. Our results suggest that EFHC1 could play an important role during cell division. (c) 2006 Elsevier Inc. All rights reserved. [less ▲]

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