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See detailLe défi des générations, sous la direction de J. Grand’Maison, L. Baroni et J.-M. Gauthier (compte rendu)
Fournier, Bernard ULg

in Recherches Sociographiques : Revue Pluridisciplinaire d'Etudes sur le Québec et le Canada français. (1999), XL(1)

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See detailDFT studies of solvation effects on the nanosize bare, thiolated and redox active ligated Au55 cluster
Periyasamy, Ganga ULg; Durgun, Engin; Raty, Jean-Yves ULg et al

in Journal of Physical Chemistry C: Nanomaterials, Interfaces, and Hard Matter (2010), Protected Metallic Clusters, Quantum Wells and Metal-Nanocrystal Molecules Symposium

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See detailDG hat niemandem in Flandern geschadet (interview de presse)
Behrendt, Christian ULg

Article for general public (2009)

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See detailDGTs, a complementary tool towards more efficient biomonitoring practices
Richir, Jonathan ULg; Lepoint, Gilles ULg; Donnay, Annick et al

Conference (2015, October 01)

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved ... [more ▼]

Among the diversity of contaminants, trace elements (TEs) remain of concern because of their persistence, their ability to accumulate in biota and their toxicity. The direct measurement of their dissolved concentrations only gives punctual and fluctuating information, and often remains below detection limits of analytical methods. The more appropriate use of sentinel organisms, or bioindicators, to monitor TEs has thus often been preferred in environmental surveys. The introduction of the diffusive gradients in thin films (DGTs) technique has however participated to progressively change this binary view - bioindicator vs water - of the coastal monitoring of TEs, and DGTs rapidly became a relevant complementary tool to bioindicators, has illustrated below. In the framework of the STARECAPMED project, the ecology and the ecotoxicology of TEs were studied in the seagrass Posidonia oceanica (L.) Delile and the mussel Mytilus galloprovincialis Lamarck, 1819. DGTs (free- and pore-water probes) were deployed before sampling of organisms. TEs were also analyzed in suspended matter (dissolved and suspended-particulate TE speciation). Studies were performed in the Calvi Bay (Corsica, France), northwestern Mediterranean. TE concentrations in organisms and suspended matter or in DGT resins were measured by DRC-ICP-MS after HNO3/H202 mineralization or after a 24h elution in HNO3 1M, respectively. (1) TE bioaccumulation was first seasonally studied in P. oceanica over 3 years. Dissolved TE concentrations monitored with DGTs were low to very low. TE bioaccumulation dynamics in P. oceanica could thus be linked to the natural physiological cycle of the plant, in clean environmental conditions. (2) To complement that field survey, isolated seagrasses were in situ contaminated with TEs at environmental relevant concentrations. Through the use of DGTs, TE uptake kinetics were modelled for seagrasses exposed to know bioavailable concentrations of contaminants, as were loss kinetics during the following depuration phase. The TE sequestration ability of a healthy P. oceanica meadow facing sudden trace metal contamination events could also be quantified. (3) The deployment of pore-water DGT probes in bare-sand or seagrass colonized sediments further showed that, through its stabilizing function of the seabed, P. oceanica maintained higher TE levels in the pore-water. P. oceanica meadows thus offer a significant “depuration-filtering” ecological service along highly anthropized Mediterranean coasts. M. galloprovincialis are widely used in large spatial scale coastal monitoring surveys. (4) The deployment of caged mussels together with DGTs showed that the little contaminated water body of the Calvi Bay was relatively homogenous. It also allowed to calculate TE bioaccumulation towards mussels in reference conditions, and to compare it to native mussel populations. (5) Finally, during a 5 months mussel caging survey, mussels and suspended matter were collected weekly to monthly, such as were deployed DGTs. The physiological status of mussels, the speciation of TEs between their dissolved and suspended-particulate phases, and their relative influence on TE bioaccumulation dynamics in mussels were investigated. In conclusion, these case studies properly demonstrate how DGT probes can be used as a relevant and complementary tool to bioindicators. Their concomitant use should therefore be privileged in monitoring surveys. [less ▲]

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See detailDHCo Délivrance d'héroïne sous contrôle médical
Ansseau, Marc ULg; Gustin, Frédéric; Hodiaumont, Fabienne et al

Book published by Academia Press (2005)

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See detailDHEA et intracrinologie de jouvence pour la peau? Entre raison et magie.
Bourguignon, Raphael; Uhoda, I.; Henry, Frédérique ULg et al

in Revue Médicale de Liège (2002), 57(7), 438-42

Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In ... [more ▼]

Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In the skin, sebaceous glands enlarge and seborrhoea increases in post-menopausal women. No other effect is clinically discernable on the skin. At this level, DHEA does not show efficacy comparable to that of other anti-ageing compounds. [less ▲]

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See detailDi sesso femminile
Tuil, Karine; Ricciardi, Stefania ULg

Book published by Voland (2005)

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See detail(Di)-aminoguanidine Functionalization through Transamination: An Avenue to an Auspicious Class of Supramolecular Synthons
Naik, Anil D; Tinant, Bernard; Léonard, Alexandre ULg et al

in Crystal Growth & Design (2011), 11

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See detail« La diabase de Challes, près de Stavelot» : Rapport sur une note de M. A. Renard par C. Malaise
Malaise, Constantin ULg

in Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Sciences (1878), 2e série(46), 186-188

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See detailDiabète : aspects particuliers. Microangiopathie et macroangiopathie diabétique
RADERMECKER, Régis ULg

Scientific conference (2011, March 18)

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See detailLe diabete de l'enfant et de l'adolescent. 1. Prise en charge par le Service Universitaire de Pediatrie et la Cellule "Education-Diabete en Pediatrie"
LEBRETHON, Marie-Christine ULg; Philippart, D.; Rocour-Brumioul, D. et al

in Revue Médicale de Liège (2005), 60(5-6, May-Jun), 313-9

The management and follow up of diabetes in youth is a multidisciplinary challenge due to both short and long term objectives. Awareness of the feelings and problems faced by the families is critical. The ... [more ▼]

The management and follow up of diabetes in youth is a multidisciplinary challenge due to both short and long term objectives. Awareness of the feelings and problems faced by the families is critical. The experience of our team has started in the 1960s and is briefly described and updated in this article. [less ▲]

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See detailLe diabète de l'enfant et de l'adolescent. 2 Aspects particuliers chez l'adolescent
BOURGUIGNON, Jean-Pierre ULg; Rocour-Brumioul, Danielle ULg; COLLARD, J et al

in Revue Médicale de Liège (2005), 60(5-6), 320-321

L'adolescent diabétique confronte les "soignants" à quelques aspects spécifiques, tant au moment du diagnostic que lors du suivi. L'existence de diabète de type 2 ne doit pas être méconnue, étant donné la ... [more ▼]

L'adolescent diabétique confronte les "soignants" à quelques aspects spécifiques, tant au moment du diagnostic que lors du suivi. L'existence de diabète de type 2 ne doit pas être méconnue, étant donné la fréquence croissante de celui-ci en relation avec la progression de l'obésité chez les sujets jeunes. Lors de l'éducation initiale, la place des parents doit être prise en compte et réfléchie, tout en créant un espace propre pour l'adolescent. Dans le suivi, toutes les dimensions du processus adolescentaire seront prises en considération en plus du diabète. Ceci implique, notamment, les comportements exploratoires ou à risques, les sentiments de marginalisation, voire la révolte, et les difficultés de prendre en compte le risque de complications à long terme. Une attention particulière sera portée sur la période de transition vers une consultation pour adultes. [less ▲]

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See detailLe diabete de type 1 et la maladie coeliaque.
Mathieu, Sandrine ULg; Stassen, A.; Paquot, Nicolas ULg et al

in Revue Médicale de Liège (2006), 61(9), 637-42

Celiac disease is more prevalent in type 1 diabetic patients than in the general population. The exact reason for this association remains unknown. Two hypotheses are taken into consideration: either a ... [more ▼]

Celiac disease is more prevalent in type 1 diabetic patients than in the general population. The exact reason for this association remains unknown. Two hypotheses are taken into consideration: either a common genetic background or an immune response against Langerhans islets triggered by celiac disease. This review presents recent data about this association and its consequences in clinical practice. [less ▲]

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See detailLe diabète de type 1: de la prédisposition génétique à un contexte environnemental hypothétique
PHILIPS, Jean-Christophe ULg; RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète/ Supplément médical (2012), 55

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See detailLe diabete de type 1: de la predisposition genetique a un contexte environnemental hypothetique.
Phlips, J.-C.; Radermecker, Régis ULg

in Revue medicale de Liege (2012), 67(5-6), 319-25

Type 1 diabetes is an autoimmune disease that results in a progressive (complete in most cases) destruction of insulin-secreting beta cells from Langerhans islets. Even if the autoimmune process becomes ... [more ▼]

Type 1 diabetes is an autoimmune disease that results in a progressive (complete in most cases) destruction of insulin-secreting beta cells from Langerhans islets. Even if the autoimmune process becomes to be well known, no one is yet sure what specifically prompts the autoimmune response that destroys the body's ability to produce insulin. Etiology of this complex disease combines a genetic predisposition and still (almost) unknown environmental factors that trigger autoimmuninty specifically targeting beta cells. Genetic HLA predispositions are clearly identified. However, only few people with apparent genetic predisposition to type 1 diabetes actually end up getting the disease. Moreover, the remarkable increase of type 1 diabetes prevalence observed in numerous countries can not be explained by genetics. Because genetic factors can't predict alone the development of type 1 diabetes, environmental factors must be involved such as viral infections, toxins from food, cow milk during childhood (instead of breast feeding) or vitamin D deficiency. This paper aims at describing the role of the genetic predisposition and the environmental hypothesis which can be involved in the development of type 1 diabetes. We will conclude by briefly describing clinical trials targeting either the immune response or the potentially toxic environment. [less ▲]

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See detailLe diabete de type 2 au coeur du syndrome metabolique: plaidoyer pour une prise en charge globale.
Scheen, André ULg; Van Gaal, L. F.

in Revue Médicale de Liège (2005), 60(5-6), 566-71

Type 2 diabetes is frequently associated with other comorbidities among which abdominal obesity, arterial hypertension, dyslipidaemia and a prothrombotic state. All these cardiovascular risk factors ... [more ▼]

Type 2 diabetes is frequently associated with other comorbidities among which abdominal obesity, arterial hypertension, dyslipidaemia and a prothrombotic state. All these cardiovascular risk factors belong to the so-called metabolic syndrome. The appropriate management of a patient with type 2 diabetes requires a global approach targeting each risk factor in order to reduce cardiovascular morbidity and mortality. Microalbuminuria is correlated with markers of the metabolic syndrome in diabetic patients as shown by the DANA survey performed among general practitioners from the areas of Liege and Antwerp and, in this type of patients, is considered as a prognostic factor of cardiovascular complications. The OCAPI study, performed among Belgian internists and diabetologists, demonstrated that two thirds of diabetic patients have a metabolic syndrome and that the objectives are far from being reached in clinical practice, especially as far as lipid and arterial pressure control is concerned. Interestingly, the Danish STENO-2 study demonstrated that an intensive multi-risk approach reduces the incidence of both micro- and macroangiopathic complications by more than 50%. This challenge represents a major public health issue considering the high and increasing prevalence of type 2 diabetes and the major burden associated to this disease. [less ▲]

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See detailDiabete de type 2 et medicaments anti-inflammatoires: nouvelles perspectives therapeutiques?
Esser, Nathalie ULg; Paquot, Nicolas ULg; SCHEEN, André ULg

in Revue Médicale Suisse (2011), 7(306), 1614-81620

It is now well accepted that a chronic, low-grade inflammation is observed in abdominal obesity, insulin resistance and type 2 diabetes mellitus, and that pro-inflammatory cytokines and oxidative stress ... [more ▼]

It is now well accepted that a chronic, low-grade inflammation is observed in abdominal obesity, insulin resistance and type 2 diabetes mellitus, and that pro-inflammatory cytokines and oxidative stress play a role in the pathogenesis of type 2 diabetes. These new findings raise the question of whether antiinflammatory strategies may have a place in the prevention and treatment of type 2 diabetes. This review article describes the results obtained in studies on patients with metabolic syndrome or type 2 diabetes aiming to test the metabolic effect of anti-inflammatory (salicylates, antagonists of interleukine-1, antagonists of tumor necrosis factor-alpha) and anti-oxydants (succinobucol) drugs. [less ▲]

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See detailLe diabète de type 2 insulinorequérant: caractéristiques des patients et effets de l'insulinothérapie
Duysinx, Bernard ULg; Scheen, A. J.; Paquot, Nicolas ULg et al

in Revue Médicale de Liège (1994), 49(6), 305-23

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