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See detailDiagnostic value of interleukine-6, transforming growth factor-beta 1 and vascular endothelial growth factor in malignant pleural effusions.
Duysinx, Bernard ULg; Corhay, Jean-Louis ULg; Hubin, Laurent et al

in Respiratory Medicine (2008), 102(12), 1708-14

STUDY OBJECTIVES: We evaluate the accuracy of pleural interleukine-6 (IL-6), transforming growth factor-beta 1 (TGF-beta1), and vascular endothelial growth factor (VEGF) levels for differentiating benign ... [more ▼]

STUDY OBJECTIVES: We evaluate the accuracy of pleural interleukine-6 (IL-6), transforming growth factor-beta 1 (TGF-beta1), and vascular endothelial growth factor (VEGF) levels for differentiating benign from malignant pleural exudates. PATIENTS AND METHODS: Levels of IL-6, TGF-beta1, and VEGF were measured by ELISA in 103 patients with non neutrophilic (<50%) exudative pleurisy including both benign and malignant effusions. Pleurisies were split into benign and malignant according to the pathological diagnosis. RESULTS: Thirty-nine benign (seven infections; 32 inflammatory diseases) and 64 malignant (34 extrathoracic tumors; 25 lung cancers; five mesotheliomas) pleural exudates were diagnosed by thoracoscopy. Pleural reticulo-monocyte count, protein Light's ratio and lactic dehydrogenase Light's ratio were significantly higher in malignant than in benign effusions (p<0.05, p<0.001 and p<0.001, respectively). The median (range) level of VEGF was significantly higher in malignant than in benign effusions (664.50 pg/ml [10-40,143] vs 349 pg/ml [10-8888]) (p<0.05). VEGF levels correlated with pleural LDH (r=0.41, p<0.0001), glucose (r=-0.30, p<0.01) and red cell count (r=0.57, p<0.0001). No significant difference was found between malignant and benign effusions with respect to IL-6 (26.8 ng/ml [1.8-421] vs 18.4 ng/ml [0.45-400], respectively) and TGF-beta1 (1079 pg/ml [18-6206] vs 1123 pg/ml [34-5447]) levels. ROC analysis between benign and malignant pleurisies for VEGF showed an area under the curve of 619 (p=0.03) with a value of 382 pg/ml as the best threshold for distinguishing benign from malignant effusions. CONCLUSIONS: Malignant effusions may enhance the release of VEGF in pleural space and its measurement may help in the diagnosis of malignant effusion. [less ▲]

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See detailDiagnostic value of neurotrophin expression in malignant pleural effusions
DUYSINX, Bernard ULg; PAULUS, Aurore ULg; HEINEN, Vincent ULg et al

in Experimental and Therapeutic Medicine (2011), 2(5), 941-946

Neurotrophins (NTs) modulate the growth of human malignancies, including lung cancers. Our prospective study evaluated the accuracy of pleural NTs [nerve growth factor, brain-derived neurotrophic factor ... [more ▼]

Neurotrophins (NTs) modulate the growth of human malignancies, including lung cancers. Our prospective study evaluated the accuracy of pleural NTs [nerve growth factor, brain-derived neurotrophic factor (BDNF), neurotrophin 3 (nT3) and 4 (nT4)] levels for differentiating benign from malignant pleural exudates. Levels of NTs were measured by ELISA in 170 patients with non-neutrophilic (<50%) exudative benign or malignant pleurisies diagnosed by pleuroscopy. Fifty-nine benign (9 infections and 50 inflammatory diseases) and 111 malignant (50 extrathoracic tumors, 51 lung cancers and 10 mesotheliomas) pleural exudates were diagnosed by thoracoscopy. Levels of BDNF were significantly higher in malignant than in benign effusions [17 pg/ml (0-367) vs. 8 pg/ml (0-51), p<0.05]. ROC analysis showed an area under the curve of 0.609 (p=0.012; best threshold 44 pg/ml). Pleural BDNF levels were significantly higher in pleural metastasis of pulmonary tumors and in mesothelioma than in pleural benign effusions. Finally, a higher proportion of pleural nT3 was detected in squamous cell lung carcinoma in comparison to that in non-squamous cell lung carcinoma (72.7 vs. 10%, p<0.0001). NTs and particularly BDNF may play a role in the pathogenesis of malignant pleural effusions. [less ▲]

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See detailDiagnostic, assessment and remediation of the attention deficit and hyperactivity disorder (ADHD): The neuropsychologist’s point of view
Catale, Corinne ULg; Meulemans, Thierry ULg

in Neuropsychiatrie de l'Enfance et de l'Adolescence (2013), 3

Despite the advances made regarding both the characterization and classification of the disorder (e.g., DSM-IV), the diagnosis of the Attention Deficit and Hyperactivity Disorder (ADHD) in children ... [more ▼]

Despite the advances made regarding both the characterization and classification of the disorder (e.g., DSM-IV), the diagnosis of the Attention Deficit and Hyperactivity Disorder (ADHD) in children remains very difficult. The principal aim of this paper is to present the interest of a integrative approach in the understanding, diagnosis and identification of difficulties in ADHD children. More particularly, it aims to underline the interest of the cognitive approach in the understanding of this disorder in the day-to-day life functioning, as well as the benefits of this approach when a specific remediation is planned. [less ▲]

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See detailDiagnostic, eévaluation et gestion d'un portefeuille de produits
Choffray, Jean-Marie ULg

in Chandon, Jean-Louis (Ed.) Quantitative Methods in Marketing (1982, April)

Cet article revoit les principales méthodes utilisées pour équilibrer un portefeuille de produits. Il propose un système d'aide à la décision qui repose sur une décomposition factorielle de la rentabilité ... [more ▼]

Cet article revoit les principales méthodes utilisées pour équilibrer un portefeuille de produits. Il propose un système d'aide à la décision qui repose sur une décomposition factorielle de la rentabilité et fournit une mesure du risque associé aux décisions touchant à l'équilibrage du portefeuille (investissement, désinvestissement, allocation des ressources disponibles). [less ▲]

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See detailDiagnostic: L'apport du laboratoire
Nikkels, Arjen ULg; Rentier, Bernard ULg

in Virologics (1994), 1

Chez le sujet immunodéprimé (SIDA, greffe, cancer, médicaments), la femme enceinte et le nouveau-né, la gravité potentielle des infections herpétiques exige l'instauration rapide d'un traitement efficace ... [more ▼]

Chez le sujet immunodéprimé (SIDA, greffe, cancer, médicaments), la femme enceinte et le nouveau-né, la gravité potentielle des infections herpétiques exige l'instauration rapide d'un traitement efficace. Etant donné que, chez ces sujets, des formes atypiques rendent le tableau clinique souvent déroutant, il est indispensable de pouvoir disposer de techniques diagnostiques rapides et précises. [less ▲]

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See detailDiagnostico del sindrome del canal carpiano en el caballo: 6 casos clinicos
Denoix, Jean-Marie; Romero, Antonio; Vàzquez, Francisco J et al

in Medicina Veterinaria (1996), 13

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See detailEl diagnostico neurologico por ultrasonografia II : Dopler cerebral transfontanelar
Armengol, AJ; Withofs, L; Battisti, Oreste ULg et al

in Archivos de Pediatria (1989), 40

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See detailEl diagnostico neurologico por ultrasonografia
Armengol, AJ; Withofs, L; Battisti, Oreste ULg et al

in Archivos de Pediatria (1989), 40(40), 119-134

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See detailDiagnostico precoz de gestation en Ganado ovino mediante un kit enzimoimmunoanalisis (EIA) de la glicoproteina asociada a la gestation (PAG) plasmatica.
Alabart, J. L.; Lahoz, B.; Folch, J. et al

in Proceedings of the XXXV Congreso de la Sociedad Espanola de Ovinotechnia y Caprinotecnia (SEOC) (2010, September)

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See detailDiagnostics différentiels d'une boiterie
Kaux, Jean-François ULg

Learning material (2015)

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See detailDiagnostics of the jovian aurora deduced from ultraviolet spectroscopy: Model and HST/GHRS observations
Dols, V.; Gérard, Jean-Claude ULg; Clarke, J. T. et al

in Icarus: International Journal of Solar System Studies (2000), 147(1), 251-266

A model coupling an electron energy degradation code with a detailed synthetic spectrum of the H-2 Lyman and Werner band system is used to calculate the emerging auroral ultraviolet spectra from Jupiter's ... [more ▼]

A model coupling an electron energy degradation code with a detailed synthetic spectrum of the H-2 Lyman and Werner band system is used to calculate the emerging auroral ultraviolet spectra from Jupiter's atmosphere excited by electrons with different initial energy distributions. The atmospheric model is adapted from the vertical P-T profile measured by the Galileo probe and midlatitude model hydrocarbon photochemistry. Each altitude layer, with its own gas temperature, contributes to the emergent ultraviolet spectrum and the absorbers are vertically distributed within the source region of the auroral emissions. Examples of the calculated spectra are shown to validate the synthetic spectrum and to illustrate the importance of the electron energy distribution and the vertical structure. The model is then applied to the analysis of seven HST/GHRS spectra of the 1200-1700 Angstrom region obtained with 5-Angstrom resolution at various locations in the north and south Jovian aurora. These spectra have different color ratios which characterize the energy of the precipitated electrons, although they do not have a high enough spectral resolution to permit a determination of the H-2 temperature. We find that the characteristic energy of the assumed initial Maxwellian distribution ranges between 17 and 40 keV. A clear signature of acetylene absorption is observed near 1520, 1480, and 1440 Angstrom where the C2H2 cross section shows strong absorption peaks. The acetylene column abundance overlying the emission peak varies from 0.02 to 0.2 of the methane column. A better fit is obtained for some spectra when ethane absorption is added. The C2H6 column abundance varies from 0 to 0.5 of the methane column. These changes relative to methane are presumably the result of perturbations by heat released by the fast electron thermalization and/or perturbations to the hydrocarbon chemistry resulting from the production of H atoms by the aurora, A spectrum of the Io flux tube footprint and its trailing tail shows an ultraviolet color and hydrocarbon absorption quite similar to some of the main oval spectra, This observation suggests that the electrons of the Io flux tube are energized to a few tens of keV, similar to the electron precipitated in the main ovals and polar caps. Echelle spectra between 1216 and 1220 Angstrom at 0.07 Angstrom resolution are also compared with the model fitting best the mid-resolution spectra. It is found that the effective H-2 rovibrational temperature associated with the echelle spectra are significantly higher than predicted by the mid-latitude model. A large vertical temperature gradient just above the methane homopause due to large heating by auroral precipitation is a plausible explanation for this difference. (C) 2000 Academic Press. [less ▲]

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See detailDiagnostique du syndrome d’apnées et hypopnées obstructives du sommeil par l’analyse des mouvements de la mandibule
Senny, Frédéric ULg; Destiné, Jacques ULg; Ansay, Pierre et al

Conference (2005, November)

Les mouvements de la mandibule donnent une image des efforts respiratoires, particulièrement en période d’apnées et d’hypopnées du sommeil. Ils sont donc une alternative à la pression oesophagienne. Cette ... [more ▼]

Les mouvements de la mandibule donnent une image des efforts respiratoires, particulièrement en période d’apnées et d’hypopnées du sommeil. Ils sont donc une alternative à la pression oesophagienne. Cette étude a mis en évidence le potentiel d’une analyse automatique des mouvements de la mâchoire pour le diagnostique du syndrome d’apnées et hypopnées obstructives du sommeil (SAHOS) par la mesure de l’indice d’apnées et d’hypopnées (IAH). [less ▲]

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See detailDiagnostiquer et traiter les endocardites chez le cheval.
Amory, Hélène ULg

in Nouveau Praticien Vétérinaire Equine (2008), 5

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See detailDiagnostiquer les Troubles Spécifiques de l'Apprentissage
Garcet, Serge ULg

in Revue Scientifique de l'AIGS, (1999), 2

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See detailDiagnostisch beleid bij verhoogde transaminasenspiegels
Delwaide, Jean ULg; Delfosse, V.; Detry, Olivier ULg et al

in Patient Care (Nederlandse Editie) (2001), 28(11), 33-41

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See detailLe diagnotic : une étape importante et complexe
Cornet, Annie ULg; Gavand, Alain

in Peretti, Jean-Marie (Ed.) Encyclopedie de la diversite (2012)

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See detailDiagram of the Brentano School
Dewalque, Arnaud ULg

in Kriegel, Uriah (Ed.) Handbook of Brentano and the Brentano School (in press)

Detailed reference viewed: 15 (0 ULg)