Diagnosis of TSH secreting pituitary adenomas : A changing scene
in The 85th Annual Meeting of the Endocrine Society - Abstract book (2003)Detailed reference viewed: 4 (0 ULg)
Diagnosis of vertical velocities with the QG Omega equation: a relocation method to obtain pseudo-synoptic data sets
; Beckers, Jean-Marie ;
in Deep-Sea Research Part I, Oceanographic Research Papers (2001), 48(6), 1347-1373
The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from ... [more ▼]
The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from the necessary compromise between spatio-temporal resolution and cost of hydrographic surveys. Observations of a numerical ocean model have been made in order to test the accuracy of different sampling strategies and their possible a-posteriori corrections. A simple first-order correction method, computing a pseudo-synoptic data set from a non-synoptic data set and involving a geostrophic relocation of the stations is shown to correct significantly the synopticity error in hydrographic data, derived QG vertical motion and vertical temperature fluxes. Sensitivity analyses also show that the lack of synopticity is more critical than other factors, including the sampling resolution, the level of no-motion and the analysis. (C) 2001 Elsevier Science Ltd. All rights reserved. [less ▲]Detailed reference viewed: 45 (8 ULg)
Diagnosis, pathophysiology and management of chronic migraine: a proposal of the Belgian Headache Society.
; ; MAGIS, Delphine et al
in Acta Neurologica Belgica (2015), 35(5), 437-442
This is a review of the pathophysiology of chronic migraine and of available therapies with a proposal for an algorithm of management.Detailed reference viewed: 32 (0 ULg)
Diagnosis, pathophysiology and management of chronic migraine: a proposal of the Belgian Headache Society.
; ; MAGIS, Delphine et al
in Acta neurologica Belgica (2014)
Chronic migraine (CM) is a disabling neurological condition affecting 0.5-2 % of the population. In the current third edition of the International Classification of Headache Disorders, medication overuse ... [more ▼]
Chronic migraine (CM) is a disabling neurological condition affecting 0.5-2 % of the population. In the current third edition of the International Classification of Headache Disorders, medication overuse is no longer an exclusion criterion and CM is diagnosed in patients suffering from at least 15 headache days per month of which at least eight are related to migraine. CM is difficult to treat, and preventive treatment options are limited. We provide a pathogenetic model for CM, integrating the latest findings from neurophysiological and neuroimaging studies. On behalf of the Belgian Headache Society, we present a management algorithm for CM based on the international literature and adapted to the Belgian situation. Pharmacological treatment options are discussed, and recent data on transcranial and invasive neuromodulation studies in CM are reviewed. An integrated multimodal treatment programme may be beneficial to refractory patients, but at present, this approach is only supported by a limited number of observational studies and quite variable between centres. [less ▲]Detailed reference viewed: 32 (1 ULg)
Diagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis.
DEBRAY, François-Guillaume ; ; et al
in Clinical Chemistry (2007), 53(5), 916-21
BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its ... [more ▼]
BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its diagnostic accuracy for differentiating between these 2 types of CLA has not been evaluated formally. METHODS: We conducted a retrospective study of all patients followed for mitochondrial diseases between 1985 and 2005 in a tertiary care pediatric hospital. RESULTS: At the recommended cut point of approximately 25, individual median L:P ratio demonstrated low sensitivity and specificity (77% and 91%, respectively) for differentiating between patients with enzymatically proven PDH-D (n = 11) and those with mitochondrial disease but normal pyruvate dehydrogenase (PDH) activity (non-PDH; n = 35). We observed a strong positive association between L:P ratio and blood lactate in non-PDH CLA, whereas this association was weak in PDH-D CLA. Consequently, patient classification based on median L:P ratio showed improved diagnostic accuracy at higher lactate concentrations: for lactate <2.5 mmol/L the area under the ROC curve was not statistically different from 0.5 (P = 0.3), whereas it was statistically different for lactate >2.5 mmol/L. In the 2.5 to 5.0 mmol/L lactate category, the sensitivity and specificity at an optimal cut point of 18.4 were 93% (95% CI, 77%-99%) and 71% (95% CI, 20%-96%), respectively; for lactate >5.0 mmol/L, with an optimal cut point of 25.8, sensitivity and specificity were 96% (95% CI, 77%-99%) and 100% (95% CI, 59%-100%), respectively. CONCLUSION: Usefulness of the L:P ratio for differentiating non-PDH and PDH-D types of CLA increases at higher lactate concentrations. [less ▲]Detailed reference viewed: 43 (1 ULg)
Diagnostic accuracy of computed tomography coronary angiography in routine practice
Davin, Laurent ; LANCELLOTTI, Patrizio ; et al
in Acta Cardiologica (2007), 62(4), 339-344
Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector ... [more ▼]
Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector spiral computed tomography (MSCT) for detecting coronary artery stenosis. Methods - A total of 88 consecutive patients (52 men, mean age 68 +/- 8 years) with atypical chest pain, stable angina or suspicion of ischaemia at stress test were studied by MSCT and invasive coronary angiography (ICA). The MSCT images and multiplanar reconstructions were analysed regarding the presence of >= 50% coronary artery lesion. Results - All 88 scans obtained at a mean heart rate of 68 8 beats/min were interpretable. Sixteen coronary segments were evaluated in each patient. Of the 1320 segments examined, 148 (11 %) showed poor image quality. A total of 150 significant lesions were detected using ICA, and 80 of 150 (53%) were detected by MSCT Sensitivity, specificity, positive and negative predictive values were as follows: 53%, 97%, 68%, and 94%. Fifty-four patients had >= 50% coronary stenosis. The diagnosis was confirmed by MSCT in 42 patients and correctly ruled out in 30. By patient-based analysis, positive and negative predictive values were 91 % and 71 %. Conclusion - Although its specificity is high, the sensitivity of 16-slice MSCT for detecting 2: 50% coronary stenosis in non-selected patients submitted to ICA is rather low suggesting that for daily practice the diagnostic value of this technique should be improved. [less ▲]Detailed reference viewed: 8 (2 ULg)
Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment.
Schnakers, Caroline ; Vanhaudenhuyse, Audrey ; et al
in BMC Neurology (2009), 9
BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies ... [more ▼]
BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies have investigated the accuracy of this grave clinical diagnosis. In this study, we compared consensus-based diagnoses of VS and MCS to those based on a well-established standardized neurobehavioral rating scale, the JFK Coma Recovery Scale-Revised (CRS-R). METHODS: We prospectively followed 103 patients (55 +/- 19 years) with mixed etiologies and compared the clinical consensus diagnosis provided by the physician on the basis of the medical staff's daily observations to diagnoses derived from CRS-R assessments performed by research staff. All patients were assigned a diagnosis of 'VS', 'MCS' or 'uncertain diagnosis.' RESULTS: Of the 44 patients diagnosed with VS based on the clinical consensus of the medical team, 18 (41%) were found to be in MCS following standardized assessment with the CRS-R. In the 41 patients with a consensus diagnosis of MCS, 4 (10%) had emerged from MCS, according to the CRS-R. We also found that the majority of patients assigned an uncertain diagnosis by clinical consensus (89%) were in MCS based on CRS-R findings. CONCLUSION: Despite the importance of diagnostic accuracy, the rate of misdiagnosis of VS has not substantially changed in the past 15 years. Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus. [less ▲]Detailed reference viewed: 58 (4 ULg)
Diagnostic agronomique et agro-environnemental des successions culturales en Wallonie (Belgique).
; Tychon, Bernard ; Oger, Robert
in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 27-38
La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l ... [more ▼]
La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l'échelle des régions agricoles qui composent le territoire de la Wallonie (Belgique). L'étude vise à dresser un diagnostic des performances qualitatives des successions culturales, à travers l'analyse individuelle de plusieurs de leurs composantes explicatives telles la qualité des précédents culturaux sur les cultures suivantes, le temps de retour moyen des cultures, le nombre de cultures apparaissant au cours de la succession et enfin la durée des périodes interculturales. Ces quatre composantes sont analysées à l'échelle parcellaire, les résultats étant agrégés au niveau régional. L'étude porte à la fois sur une analyse spatiale basée sur une période de 7 années, ainsi que sur une analyse temporelle visant à observer une éventuelle évolution, région par région, au cours de deux périodes successives de même durée. L'état des lieux ainsi dressé révèle des différences spatiales en termes de pratiques liées aux successions culturales, par contre, une quasi-stabilité dans le temps des paramètres analysés découle des résultats obtenus. Par ailleurs, si ces résultats contribuent à enrichir un état des lieux de l'agriculture en Wallonie, ils peuvent en outre servir de valeurs de référence pour un suivi global de l'évolution des pratiques agricoles régionales. [less ▲]Detailed reference viewed: 74 (13 ULg)
Diagnostic and prognostic use of bispectral index in coma, vegetative state and related disorders
Schnakers, Caroline ; Ledoux, Didier ; Majerus, Steve et al
in Brain Injury (2008), 22(12), 926-931Detailed reference viewed: 51 (5 ULg)
Diagnostic and technical report of hatchery in Attapeu
Report (2014)Detailed reference viewed: 27 (11 ULg)
Diagnostic and therapeutic management of carcinoma of unknown primary: radio-imaging investigations.
Jerusalem, Guy ; Rorive, Andrée ; et al
in Annals of Oncology (2006), 17 Suppl 10Detailed reference viewed: 13 (3 ULg)
Diagnostic antenatal des affections du stystème nerveux central: résultats préliminaires d'une série multicentrique européenne de 350 cas
; Misson, Jean-Paul ;
in Journal Français d'Echographie (1984), 2(4), 123-123Detailed reference viewed: 30 (10 ULg)
Diagnostic approach of early postnatal salt wasting : lessons from a clinical case
FUDVOYE, Julie ; BOURGUIGNON, Jean-Pierre ; LEBRETHON, Marie-Christine et al
Conference (2014, March)Detailed reference viewed: 35 (8 ULg)
Diagnostic challenges of cystic fibrosis in patients of African origin.
; Bours, Vincent
in Journal of Tropical Pediatrics (2009), 55(5), 281-6Detailed reference viewed: 29 (1 ULg)
Diagnostic Characteristics and Therapeutic Responses in Acromegaly : The Liège Acromegaly Survey
; Petrossians, Patrick ; Daly, Adrian et al
in 50th Meeting of the German Endocrine Society and 23rd Meeting of Dutch Endocrine Society : Essen, Germany, 1-4 March 2006 (2006, March)Detailed reference viewed: 18 (1 ULg)
Le diagnostic clinique et les examens complémentaires en pneumologie chez le chien et le chat
in Nouveau praticien vétérinaire, Hors série : diagnostic et examens complémentaires (2004)Detailed reference viewed: 27 (0 ULg)