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See detailEfficiency of a French-language triage algorithm in the Emergency Department
JOBE, Jérôme ULg; Ghuysen, Alexandre ULg; GERARD, P et al

in Critical Care Medicine (2011), 15(suppl 1), 455

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See detailEfficiency of a Lactobacillus plantarum-xylanase combination on growth performances, microflora populations, and nutrient digestibilities of broilers infected with Salmonella Typhimurium
Vandeplas, Sabrina ULg; Dubois Dauphin, Robin ULg; Thiry, Christophe ULg et al

in Poultry Science (2009), 88(8), 1643-1654

Three experiments were performed to assess the ability of a Lactobacillus plantarum probiotic combined with a xylanase to reduce the effects of S. typhimurium infection in broiler chickens from 1- to 30 ... [more ▼]

Three experiments were performed to assess the ability of a Lactobacillus plantarum probiotic combined with a xylanase to reduce the effects of S. typhimurium infection in broiler chickens from 1- to 30- or 42-d-old. Chicks were challenged at 3-d-old with 108 or 105 cfu S. typhimurium/chick. Four diets were studied: a wheat-based diet (C+) supplemented with 0.1 g/kg xylanase (E), or 106 cfu/g or L. plantarum (P), or both (PE). Uninfected chicks fed the C diet were used as negative control (C-). Six or 8 chicks were housed per cage with 9 cages/treatment. Growth performance and feed conversion ratio (FCR) were recorded weekly. In experiment 1, bacterial enumeration in caeca was achieved using the fluorescent in situ hybridization technique. Salmonella enumeration was realized in excreta by microbiological cultures (Exp. 2 and 3). Nutrient digestibilities and AMEn were determined in experiment 3 from d 35 to d 39. Infection with S. typhimurium led to a significant decrease in the daily weight gain (DWG) by 23.6% to 32.8%, whereas FCR was increased by 1.0% to 19.7%. Chickens fed the PE diet showed significantly improved performance in comparison with C+ birds (DWG: +12.5% in Exp. 1; FCR: -2.1-8.6%), and in comparison with the P and E treatments (DWG: +6.3-8.3% in Exp. 1; FCR: -2.7-6.4%). In experiment 3, the FCR was significantly improved by 3% with the PE diet in comparison with C- chickens. The PE combination tended to restore a microflora similar to that of uninfected broilers, whereas the P and E diets had less of an effect on the profile of bacterial communities. At slaughter age, Salmonella contamination was reduced by 2.00 and 1.85 log cfu for the E and PE treatment, respectively. The PE diet significantly reduced the crude fat digestibility by 9.2%, in comparison with the C+ chickens. These results suggest that combination between L. plantarum and a xylanase as feed additive could be effective for reduction of detrimental effect following S. typhimurium infection of broilers. [less ▲]

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See detailEfficiency of Acanthamoeba castellanii uncoupling protein in energy-dissipating processes
Jarmuszkiewicz, W.; Hryniewiecka, L.; Sluse-Goffart, C. et al

in Hofmeyr, J.; Rohwer, J. M.; Snoops, J. L. (Eds.) Biothermokinetic 2000 : Animating the cellular map (2000)

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See detailEfficiency of an autobiographical memory remediation therapy in schizophrenia patients
Blairy, Sylvie ULg; Neumann, Aurore; Philippot, Pierre

Conference (2006, May 19)

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See detailEfficiency of Belgian hospitals: a frontier approach based on financial and clinical minimum basic data sets
Fecher-Bourgeois, Fabienne ULg; Closon, Marie-Christine; Pouplier, Isabelle

Report (1996)

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See detailEfficiency of calcium and vitamin D supplementation in the management of osteoporosis
Hiligsmann, Mickaël ULg; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Osteoporosis International (2008, April), 19(S1), 113

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See detailEfficiency of day seven collection of bovine embryosafter superovulation by flushing the oviducts and the uterin horns.
Havlicek, V.; Kuzmany, A.; Beckers, Jean-François ULg et al

in Reproduction, Fertility and Development (2010), 22(1), 363

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See detailThe efficiency of different simulation-based design methods in improving building performance
Nguyen, Anh Tuan; Reiter, Sigrid ULg

in Brebbia,, C.A.,; Pulselli, R. (Eds.) WIT Transactions on Ecology on The Built Environment, vol. 142 (2014, September)

This paper presents a pioneering effort to define the efficiency of the most common simulation-based design methods, namely the parametric simulation method (PSM) and the simulation-based optimization ... [more ▼]

This paper presents a pioneering effort to define the efficiency of the most common simulation-based design methods, namely the parametric simulation method (PSM) and the simulation-based optimization method (SOM), in improving two building performance indicators: thermal comfort and energy consumption. Three case-study houses were selected and their indoor conditions were continuously monitored during one summer month in 2012. Computer EnergyPlus models of these houses were established and then carefully calibrated by the monitoring data to improve the reliability of the numerical methods. Thermal performances of these houses during a year were simulated, then improved by the PSM and finally optimized by the SOM. By comparing the results of these two simulation-based design methods, this research found that both the PSM and SOM were very effective in improving these building performance indicators. This study found that the SOM is almost two times more efficient than the PSM in improving thermal comfort in naturally ventilated (NV) houses and life cycle cost in air-conditioned (AC) houses. In average, the discomfort period in NV houses could be reduced by 44.9% by the PSM while as high as 86.1% by the SOM, compared with the reference cases. The life cycle cost of AC houses had smaller reductions with 6.2% and 14.6% cut-off by the PSM and SOM, respectively. The results of this work give a strong and explicit insight of the actual efficiency of each design method. This work also shows great advantages of applications of advanced numerical approaches in the design of high performance buildings. [less ▲]

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See detailEfficiency of elisa : a new french-language triage algorithm
JOBE, Jérôme ULg; Ghuysen, Alexandre ULg; Gerard, P. et al

in Acta Clinica Belgica (2011)

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See detailEfficiency of embryonic development after Intra-Follicular and Intra-Oviductal transfer of in vitro and in vivo matured horse oocytes
Deleuze, Stefan ULg; Goudet, Ghylène; Caillaud, Maud et al

in Theriogenology (2009), 72(2), 203

In vivo techniques, such as intra-oviductal Oocyte Transfer (OT) and Intra-Follicular Oocyte Transfer (IFOT) can be considered as alternatives to bypass the lack of efficient superovulation treatments and ... [more ▼]

In vivo techniques, such as intra-oviductal Oocyte Transfer (OT) and Intra-Follicular Oocyte Transfer (IFOT) can be considered as alternatives to bypass the lack of efficient superovulation treatments and the inadequacy of conventional in vitro fertilization techniques in the horse. We compared embryo production following transfer of in vivo recovered oocytes (1) into a recipient’s oviduct or (2) into her preovulatory follicle either immediately after ovum pick up or (3) after in vitro maturation. Recipients were inseminated with fresh semen of a stallion with a known normal fertility. Ten days after surgery, rates of embryos collected in excess to the number of ovulations were calculated and compared for each group. Embryo collection rates were 32.5% (13/40), 5.5% (3/55) and 12.8% (6/47) for OT, post-IVM and immediate IFOT respectively. OT significantly yielded more embryos than immediate and post-IVM IFOT did. We also showed that in vitro matured oocytes could succesfully be used for IFOT. Our results also suggest that improvement of the IFOT technique could turn it into an inexpansive and easy to perform procedure that could be an answer to the inefficiency of superovulation treatments in the mare. [less ▲]

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See detailEfficiency of haplotype-based methods to fine-map QTLs and embryonic lethal variants affecting fertility: Illustration with a deletion segregating in Nordic Red cattle
Kadri, Naveen Kumar ULg; Sahana, Goutam; Guldbrandtsen, Bernt et al

in Livestock Science (2014), 166

Despite its importance, fertility has been declining in many cattle populations. In dairy cattle, this decline is often attributed to the negative correlation between fertility and productions traits ... [more ▼]

Despite its importance, fertility has been declining in many cattle populations. In dairy cattle, this decline is often attributed to the negative correlation between fertility and productions traits. Recent studies showed that embryonic lethal variants might also account for a non-negligible fraction of the fertility decline. Therefore identification of such embryonic lethal variants is essential to improve fertility. We herein illustrate, with an example of a large recessive lethal deletion recently identified in Nordic Red cattle, that haplotype-based method are particularly efficient to identify such embryonic lethal variants. We first show that haplotypes can be used in traditional QTL mapping approaches and that they present very high linkage disequilibrium with underlying variants. Haplotypes can also be used in scan for lack of homozygosity. Indeed,if a haplotype is associated to a recessive lethal variant, significantly fewer living individuals will be homozygote for that haplotype than expected. For both approaches, haplotype- based methods were particularly efficient. The lack of homozygosity approach achieved higher significance than the QTL approach. Only frequent variants can be detected with both approaches unless huge genotyped cohorts are available. An alternative approach would rely on identifying potential harmful variants in next-generation sequencing data followed by the genotyping of a larger population for these variants. [less ▲]

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See detailThe Efficiency of In vitro Ovine Embryo Production Using an Undefined or a Defined Maturation Medium is Determined by the Source of the Oocyte.
Cocero, M.; Alabart, J.; Hammami, S. et al

in Reproduction in Domestic Animals (2011), 46(3), 463-470

In vitro oocyte maturation can be influenced by oocyte source and maturation media composition. The aim of the present study was to compare the efficiency of a defined in vitro maturation medium (TCM199 ... [more ▼]

In vitro oocyte maturation can be influenced by oocyte source and maturation media composition. The aim of the present study was to compare the efficiency of a defined in vitro maturation medium (TCM199 supplemented with cysteamine and epidermal growth factor; Cys + EGF) with an undefined medium (TCM199 supplemented with follicle-stimulating hormone and follicular fluid; FSH + FF) for in vitro production (IVP) of ovine embryos, using oocytes obtained by laparoscopic ovum pick-up from FSH-stimulated [n = 11; 158 cumulus-oocyte complexes (COCs)] and non-stimulated (n = 16; 120 COCs) live ewes, as well as abattoir-derived oocytes (170 COCs). The produced blastocysts were vitrified and some of them were transferred to synchronized recipients. The best and the worst final yields of embryo IVP observed in this study were obtained using oocytes from FSH-stimulated ewes matured in FSH + FF (41.3%; 33/80) and in Cys + EGF (19.2%; 15/78) medium, respectively (p < 0.01). No significant differences between both media were attained in the blastocyst development rate or in the final yield of embryo IVP using oocytes from non-stimulated ewes or abattoir-derived oocytes. The overall in vivo survival rate of the transferred vitrified blastocysts was 13.1% (8/61), without significant differences between oocyte sources or maturation media. In conclusion, under the experimental conditions of the present study, TCM199 supplemented with cysteamine and EGF is a convenient defined maturation medium for IVP of embryos from oocytes of live non-stimulated ewes or from oocytes of abattoir-derived ovaries. However, the best final yield of embryo IVP observed in this study was attained when oocytes came from FSH-stimulated donors and TCM199 was supplemented with FSH and follicular fluid [less ▲]

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See detailEfficiency of inventory plot patterns in quantitative analysis of vegetation : a case study of tropical woodland and dense forest in Benin
Salako, Valère K.; Glele Kakai, Romain L.; Assogbadjo, Achille E. et al

in Southern Forests : a Journal of Forest Science (2013), 75(3), 137-143

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See detailEfficiency of sieving or classification for dry fractionation of aot mills and beta-glucans enrichment.
Roiseux, Olivier; Vanderbeke, E.; Blecker, Christophe ULg et al

Poster (2008, June)

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See detailEfficiency of T Cell Triggering by Anti-Cd3 Monoclonal Antibodies (Mab) with Potential Usefulness in Bispecific Mab Generation
Jacobs, Nathalie ULg; Mazzoni, A.; Mezzanzanica, D. et al

in Cancer Immunology, Immunotherapy (1997), 44(5), 257-64

T cell triggering can be achieved by monoclonal antibodies (mAbs) specific for the CD3/TcR complex. In the presence of appropriate costimulation and/or progression factors, such triggering permits the ... [more ▼]

T cell triggering can be achieved by monoclonal antibodies (mAbs) specific for the CD3/TcR complex. In the presence of appropriate costimulation and/or progression factors, such triggering permits the generation of effector cells for immunotherapy protocols involving the redirection of T cell lysis against tumor cells by mAbs bispecific for anti-CD3/anti-tumor cells (bs-mAbs). Focusing our analysis on the clinically relevant bs-mAb OC/TR, we found that bs-mAbs generated with the same anti tumor specificity, but two other anti-CD3 mAbs, TR66 and OKT3, have the same and a significantly lower lytic potential, respectively, compared with that of OC/TR. To evaluate the relevance of the anti-CD3 component, we examined several anti-CD3 mAbs with respect to binding parameters and the ability to trigger T lymphocytes. Competitive binding assays suggested that all anti-CD3 mAbs recognized the same or overlapping epitopes, although mAbs BMA030 and OC/TR bound with lower avidity than did alpha CD3 (the bivalent anti-CD3 mAb produced by the hybrid hybridoma OC/TR). TR66 and OKT3, as determined by measurement of the affinity constants. In all lymphocyte populations examined, which included resting peripheral blood mononuclear cells (PBMC), activated PBMC and T cell clones, OKT3, BMA033 and OC/TR failed to mobilize Ca2+ without cross-linking, whereas alpha CD3, in both murine and murine-human chimeric versions, TR66 and BMA030, did not require cross-linking. The ability to induce CD3 modulation was associated in part with the induction of Ca2+ fluxes. Despite the differences in the behavior of these mAbs in triggering the events that precede proliferation, all of them ultimately led to expression of the IL-2 receptor and to proliferation in T cells in the presence of accessory cells. Our data suggest that anti-CD3 mAbs that bind more rapidly (strong Ca2+ mobilizers) and more tightly under physiological conditions are good candidates for retargeting T cells in the bs-mAb clinical application. [less ▲]

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See detailEfficiency of Targeted Energy Transfers in Coupled Nonlinear Oscillators Associated with 1:1 Resonance Captures
Sapsis, T.; Vakakis, Alexander F.; Gendelman, O. V. et al

in 45th Technical Meeting of the Society of Engineering Science, Urbana Champaign, 2008 (2008)

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See detailEfficiency of targeted energy transfers in coupled nonlinear oscillators associated with 1:1 resonance captures:Part II, analytical study
Sapsis, T. P.; Vakakis, Alexander F.; Gendelman, O. V. et al

in Journal of Sound & Vibration (2009)

We study targeted energy transfer in a two degree-of-freedom damped system under the conditionof1:1transient resonance capture. The system consists of a linear oscillator strongly coupled to an ... [more ▼]

We study targeted energy transfer in a two degree-of-freedom damped system under the conditionof1:1transient resonance capture. The system consists of a linear oscillator strongly coupled to an essentially nonlinear attachment or nonlinear energy sink. In a companion paper[ Quinnetal., Efficiency of targeted energy transfers in coupled nonlinear oscillators associated with1:1resonance captures: part I, Journal of Sound and Vibration 311 (2008)1228–1248]we studied the under lying structure of the Hamiltonian dynamics of this system ,and showed that for sufficiently small values of viscous damping , nonlinear damped transitions are strongly influenced by the under lying topological structure of periodic and quasi periodic or bits of the Hamiltonian system. In this work direct analytical treatment of the governing strongly nonlinear damped equations of motion is performed through slow/fast partitions of the transient responses, in order to investigate analytically the parameter region of optimal targeted energy transfer .To this end, we determine the characteristic time scales of the dynamics that influence the capacity of the nonlinear attachment to passively absorb and locally dissipate broad band energy from the linear oscillator. Then, we prove that optimal targeted energy transfer is realized for initial energies close to the neighbourhood of a homo clinic or bit of the under lying Hamiltonian system. We study analytically transient orbits resulting as perturbations of the homo clinic or bit in the weak lydamped system, and show that this yields an additional slow-time scale in the averaged dynamics, and leads to optimal targeted energy transfer from the linear oscillator to the nonlinear energy sink in a single ‘‘super-slow’’ half-cycle. We show that at higher energies, this ‘‘super-slow’’ half-cycle is replaced by strong nonlinear beats, which lead to significant but suboptimal targeted energy transfer efficiency. Finally, we investigate numerically targeted energy transfer efficiency in this system over a wide range of system parameter sand verify the analytical predictions. 2009 Elsevier Ltd .All rights reserved. [less ▲]

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