Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailDelayed Paraplegia After Endovascular Treatment of a Thoracoabdominal Aortic Aneurysm Successfully Managed Using Cerebrospinal Fluid Drainage.
Azevedo Mendes, Manuel; Szecel, Delphine; Hans, Greogry A. et al

in Journal of Cardiothoracic and Vascular Anesthesia (2016)

Detailed reference viewed: 24 (4 ULiège)
Full Text
Peer Reviewed
See detailDelayed puberty in a girl due to an inactivating mutation of the LH receptor
FUDVOYE, Julie ULiege; PARENT, Anne-Simone ULiege; Bourguignon, Jean-Pierre ULiege

Poster (2012, March)

We report the case of a 46 XY patient with a disorder of sex differentiation (DSD) caused by an inactivating mutation of the LH receptor. Mutations of genes involved in hypothalamic-pituitary-gonadal ... [more ▼]

We report the case of a 46 XY patient with a disorder of sex differentiation (DSD) caused by an inactivating mutation of the LH receptor. Mutations of genes involved in hypothalamic-pituitary-gonadal function are rare but they provide an experience of nature for understanding the physiology and the pathophysiology of gonadotropins actions. There arise from correlation between the phenotypes and genotypes in those unique conditions. Management of this particular patient with no LH activity involves oestrogen replacement therapy to induce breast development together with a gonadectomy due to the risk of gonadoblastoma in streak gonads. [less ▲]

Detailed reference viewed: 16 (1 ULiège)
Full Text
Peer Reviewed
See detailDelayed reepithelialization and scarring deregulation following drug-induced toxic epidermal necrolysis.
Paquet, Philippe ULiege; Jacob, E.; Quatresooz, Pascale ULiege et al

in Burns (2007), 33(1), 100-4

A 51-year-old Caucasian woman developed severe drug-induced toxic epidermal necrolysis (TEN) due to allopurinol. The withdrawal of the culprit drug was unfortunately delayed, and dramatic retardation of ... [more ▼]

A 51-year-old Caucasian woman developed severe drug-induced toxic epidermal necrolysis (TEN) due to allopurinol. The withdrawal of the culprit drug was unfortunately delayed, and dramatic retardation of reepithelialization was observed. At that stage of disease evolution, an inflammatory cell infiltrate was present in the dermis. Coverage of eroded lesions by frozen cultured keratinocyte allografts failed to hasten reepithelialization compared to ungrafted sites. This unusual protracted TEN evolution was followed by the development of extensive hypertrophic and keloid scars. Several biopsies were taken over 6 months. The histologic presentation of the grafted and ungrafted eroded scar tissues looked similar. Both the number and size of the Factor XIIIa-positive dermal dendrocytes, as well as the number of alpha-actin-positive myofibroblasts showed a marked increase between weeks 2 and 12 after grafting. They were reduced after 6 months when the scarring process was stabilized. alpha1 [IV] collagen was never expressed over the eroded scars. Similar to burn patients, delayed reepithelialization might be a risk factor for abnormal scarring in TEN. Cultured keratinocyte allograft apparently offered no improvement in reepithelialization and did not prevent abnormal scarring in this TEN patient. [less ▲]

Detailed reference viewed: 39 (7 ULiège)
Full Text
See detailDelayed-Onset Muscle Soreness : treatment or prevention ?
Hody, Stéphanie ULiege

Conference (2009, March 05)

Detailed reference viewed: 54 (13 ULiège)
See detailDelayed-onset profound biotinidase deficiency.
Wolf, B.; Pomponio, R. J.; Norrgard, K. J. et al

in The Journal of pediatrics (1998), 132(2), 362-5

Children with biotinidase deficiency usually exhibit symptoms at several months to years of age. We describe four children who had symptoms later in childhood or during adolescence; they had motor limb ... [more ▼]

Children with biotinidase deficiency usually exhibit symptoms at several months to years of age. We describe four children who had symptoms later in childhood or during adolescence; they had motor limb weakness, spastic paresis, and eye problems, such as loss of visual acuity and scotomata, rather than the more characteristic symptoms observed in young untreated children with the disorder. These older children each have different mutations, but they are the same as those of children who have exhibited symptoms at an early age. Biotinidase deficiency should be considered in older children who suddenly experience limb weakness and/or spastic paresis and eye symptoms. [less ▲]

Detailed reference viewed: 17 (5 ULiège)
Full Text
Peer Reviewed
See detailDelayed-onset profound biotnidase deficiency
Wolf, B.; Pomponio, R.; Norrgard, K. et al

in Journal of Pediatrics (1998), 132(2), 362-365

Children with biotinidase deficiency usually exhibit symptoms at several months to years of age. We describe four children who had symptoms later in childhood or during adolescence; they had motor limb ... [more ▼]

Children with biotinidase deficiency usually exhibit symptoms at several months to years of age. We describe four children who had symptoms later in childhood or during adolescence; they had motor limb weakness, spastic paresis, and eye problems, such as loss of visual acuity and scotomata, rather than the more characteristic symptoms observed in young untreated children with the disorder. These older children each have different mutations, but they are the same as those of children who have exhibited symptoms at on early age. Biotinidase deficiency should be considered in older children who suddenly experience limb weakness and/or spastic paresis and eye symptoms. [less ▲]

Detailed reference viewed: 19 (0 ULiège)
Full Text
Peer Reviewed
See detailDelays in claiming social security benefits
Jousten, Alain ULiege; Diamond, P.; Coile, C. et al

in Journal of Public Economics (2002), 84

This paper focuses on Social Security benefit claiming behavior, a take-up decision that has been ignored in the previous literature. Using financial calculations and simulations based on an expected ... [more ▼]

This paper focuses on Social Security benefit claiming behavior, a take-up decision that has been ignored in the previous literature. Using financial calculations and simulations based on an expected utility maximization model, we show that delaying benefit claim for a period of time after retirement is optimal in a wide variety of cases and that gains from delay may be significant.We find that approximately 10% of men retiring before their 62nd birthday delay claiming for at least 1 year after eligibility. We estimate hazard and probit models using data from the New Beneficiary Data System to test four cross-sectional predictions. While the data suggest that too few men delay, we find that the pattern of delays by early retirees is generally consistent with the hypotheses generated by our theoretical model. [less ▲]

Detailed reference viewed: 20 (1 ULiège)
See detailDelays in the apoptotic switch: look for the hidden saddle
Trotta, Laura ULiege; Sepulchre, Rodolphe ULiege; Bullinger, Eric ULiege

Poster (2011, March 21)

Detailed reference viewed: 30 (2 ULiège)
Full Text
Peer Reviewed
See detailDelegation and Information Revelation
Gautier, Axel ULiege; Paolini, Dimitri

in Journal of Institutional and Theoretical Economics = Zeitschrift für die Gesamte Staatswissenschaft (2007), 163

This paper analyzes, in a set-up where only the control over actions is contractible, the rationale for delegation. An organization must take two decisions. The payoffs are affected by a random parameter ... [more ▼]

This paper analyzes, in a set-up where only the control over actions is contractible, the rationale for delegation. An organization must take two decisions. The payoffs are affected by a random parameter and only the agent knows its realization. If the principal delegates the control over the first decision to the agent, his choice may indicate the information that he possesses. If the principal retains control over the second decision, discovering this information is valuable. Hence, this paper provides a new rationale for delegation: A transfer of control to the informed party can be used to discover the private information. (JEL: D23, D82, L22 , M41) [less ▲]

Detailed reference viewed: 25 (5 ULiège)
Full Text
See detailDélégation par abandon ; approche psychologique
Born, Michel ULiege

in Les politiques sociales (1999), 3-4

Detailed reference viewed: 138 (5 ULiège)
Full Text
Peer Reviewed
See detailDelegation, externalities and organizational design
Gautier, Axel ULiege; Paolini, Dimitri

in Economics Bulletin (2009), 29(4),

In a repeated interaction between a principal and two agents with inter-agents externalities and asymmetric information, we show that optimal decentralization within the organization is limited to the ... [more ▼]

In a repeated interaction between a principal and two agents with inter-agents externalities and asymmetric information, we show that optimal decentralization within the organization is limited to the first period and across agents. [less ▲]

Detailed reference viewed: 67 (13 ULiège)
Full Text
See detailLe délégué à la gestion journalière et les délégations particulières de pouvoir
Caprasse, Olivier ULiege

in L'organisation du pouvoir dans la société anonyme (2004)

Detailed reference viewed: 153 (10 ULiège)
Full Text
Peer Reviewed
See detailDeleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
Lopez-Herrera, Gabriela; Tampella, Giacomo; Pan-Hammarstrom, Qiang et al

in American Journal of Human Genetics (2012), 90(6), 986-1001

Most autosomal genetic causes of childhood-onset hypogammaglobulinemia are currently not well understood. Most affected individuals are simplex cases, but both autosomal-dominant and autosomal-recessive ... [more ▼]

Most autosomal genetic causes of childhood-onset hypogammaglobulinemia are currently not well understood. Most affected individuals are simplex cases, but both autosomal-dominant and autosomal-recessive inheritance have been described. We performed genetic linkage analysis in consanguineous families affected by hypogammaglobulinemia. Four consanguineous families with childhood-onset humoral immune deficiency and features of autoimmunity shared genotype evidence for a linkage interval on chromosome 4q. Sequencing of positional candidate genes revealed that in each family, affected individuals had a distinct homozygous mutation in LRBA (lipopolysaccharide responsive beige-like anchor protein). All LRBA mutations segregated with the disease because homozygous individuals showed hypogammaglobulinemia and autoimmunity, whereas heterozygous individuals were healthy. These mutations were absent in healthy controls. Individuals with homozygous LRBA mutations had no LRBA, had disturbed B cell development, defective in vitro B cell activation, plasmablast formation, and immunoglobulin secretion, and had low proliferative responses. We conclude that mutations in LRBA cause an immune deficiency characterized by defects in B cell activation and autophagy and by susceptibility to apoptosis, all of which are associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity. [less ▲]

Detailed reference viewed: 143 (5 ULiège)
Full Text
Peer Reviewed
See detailDeletion (6)(p22p25) is a recurrent anomaly of thymoma: report of a second case and review of the literature
Herens, Christian ULiege; Radermecker, Maurice ULiege; Servais, Anne-Marie ULiege et al

in Cancer Genetics & Cytogenetics (2003), 146(1), 66-69

A patient with type AB thymoma and del(6)(p22p25) as the sole cytogenetic anomaly is described. This is the second report of a del(6)(p22p25) in a thymoma. The same deletion was previously found in ... [more ▼]

A patient with type AB thymoma and del(6)(p22p25) as the sole cytogenetic anomaly is described. This is the second report of a del(6)(p22p25) in a thymoma. The same deletion was previously found in association with a type A thymoma. Both patients presented with benign tumors. These data suggest that partial deletion of the short arm of chromosome 6 is a nonrandom change associated with benign thymomas. (C) 2003 Elsevier Inc. All rights reserved. [less ▲]

Detailed reference viewed: 20 (3 ULiège)
Full Text
Peer Reviewed
See detailDeletion Analogues Of Transportan
Soomets, U.; Lindgren, M.; Gallet, X. et al

in Biochimica et Biophysica Acta-Biomembranes (2000), 1467(1), 165-76

Several shorter analogues of the cell penetrating peptide, transportan, have been synthesized in order to define the regions of the sequence, which are responsible for the membrane translocation property ... [more ▼]

Several shorter analogues of the cell penetrating peptide, transportan, have been synthesized in order to define the regions of the sequence, which are responsible for the membrane translocation property of the peptide. Penetration of the peptides into Bowes melanoma cells and the influence on GTPase activity in Rin m5F cellular membranes have been tested. The experimental data on cell penetration have been compared with molecular modeling of insertion of peptides into biological membranes. Omission of six amino acids from the N-terminus did not significantly impair the cell penetration of the peptide while deletions at the C-terminus or in the middle of the transportan sequence decreased or abolished the cellular uptake. Most transportan analogues exert an inhibitory effect on GTPase activity. Molecular modeling shows that insertion of the transportan analogues into the membrane differs for different peptides. Probably the length of the peptide as well as the location of aromatic and positively charged residues have major impact on the orientation of peptides in the membranes and thereby influence the cellular penetration. In summary, we have designed and characterized several novel short transportan analogues with similar cellular translocation properties to the parent peptide, but with reduced undesired cellular activity. [less ▲]

Detailed reference viewed: 23 (0 ULiège)
Full Text
Peer Reviewed
See detailA deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina.
Charlier, Carole ULiege; Agerholm, Jorgen Steen; Coppieters, Wouter ULiege et al

in PLoS ONE (2012), 7(8), 43085

Fertility is one of the most important traits in dairy cattle, and has been steadily declining over the last decades. We herein use state-of-the-art genomic tools, including high-throughput SNP genotyping ... [more ▼]

Fertility is one of the most important traits in dairy cattle, and has been steadily declining over the last decades. We herein use state-of-the-art genomic tools, including high-throughput SNP genotyping and next-generation sequencing, to identify a 3.3 Kb deletion in the FANCI gene causing the brachyspina syndrome (BS), a rare recessive genetic defect in Holstein dairy cattle. We determine that despite the very low incidence of BS (<1/100,000), carrier frequency is as high as 7.4% in the Holstein breed. We demonstrate that this apparent discrepancy is likely due to the fact that a large proportion of homozygous mutant calves die during pregnancy. We postulate that several other embryonic lethals may segregate in livestock and significantly compromise fertility, and propose a genotype-driven screening strategy to detect the corresponding deleterious mutations. [less ▲]

Detailed reference viewed: 33 (4 ULiège)