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See detail2.8-Å Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with β-lactams
Kelly, Judith A; Knox, James R; Moews, Paul C et al

in Journal of Biological Chemistry (1985), 260(10), 6449-6458

The crystallographic structure of the penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 has been solved to 2.8-A resolution. The 38,000-dalton serine peptidase has two ... [more ▼]

The crystallographic structure of the penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 has been solved to 2.8-A resolution. The 38,000-dalton serine peptidase has two regions of secondary structure, an alpha/beta cluster, and a region which contains five helical segments. The beta sheet is composed of five beta strands. The tertiary structure has no homology with the classic serine proteases or with the zinc carboxypeptidases. The binding at a common site of three types of beta-lactam (a penicillin, a cephalosporin, a monocyclic beta-lactam) and a desazacyclobutanone has been observed in Fourier difference maps. The binding site sequence is Val-Gly-Ser-Val-Thr-Lys. The beta-lactam ring lies near the enzyme's catalytic serine at position 37, and the C3 substituent of a cephalosporin falls near lysine 40. [less ▲]

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See detail20 ans d'études dans 2 bassins versants boisés en Ardenne
Guillaume, Patricia; Bosman, Bernard ULiege; Bazgir, Masoud et al

Diverse speeche and writing (2011)

En Région wallonne, de nombreux sols forestiers se caractérisent par un pH faible et une pauvreté en Ca, P et surtout Mg. Depuis 1991, dans le cadre d’études sur le dépérissement forestier et l’impact de ... [more ▼]

En Région wallonne, de nombreux sols forestiers se caractérisent par un pH faible et une pauvreté en Ca, P et surtout Mg. Depuis 1991, dans le cadre d’études sur le dépérissement forestier et l’impact de mesures de gestion forestière, le laboratoire d’Ecologie Végétale et Microbienne (ULg) étudie l’évolution des concentrations et des flux en éléments minéraux dans les principaux compartiments de deux bassins versants. Ce triptyque résume une partie de ces recherches. [less ▲]

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See detail20 ans de formation ! et demain ?
Morant, Michel ULiege

Conference (2011, June 08)

La présentation met en évidence les besoins nouveaux dans les compétences requises pour un gestionnaire de transfert de technologie ou agent de valorisation

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See detail20 ans de valorisation dans l'Espace Wallonie-bruxelles
Morant, Michel ULiege

Conference (2011, June 06)

La présentation brosse 2à années d'évolution des universités en Wallonie en matière de 3e mission, et en particulier de la valorisation économique de la recherche

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See detailLes 20 ans du Cifen : bienvenue
Simons, Germain ULiege

Speech/Talk (2015)

Mot de bienvenue aux participants à la cérémonie des 20 ans d'existence officielle du Centre interfacultaire de formation des enseignants (Cifen) de l'ULg

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See detail20 Hypertelescope concepts: from Carlina prototypes into space
Labeyrie, Antoine; Mourard, Denis; Le Coroller, Hervé et al

in Pott, Jörg-Uwe; Surdej, Jean (Eds.) Future of optical-infrared interferometry in Europe (2017)

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See detail20 mai 1876 : augmentation des inscriptions et extension des bâtiments
Frankignoulle, Pierre ULiege

Article for general public (2016)

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See detail20 years of NF-kappa B
Chariot, Alain ULiege

in Biochemical Pharmacology (2006), 72(9), 1051-1053

We are celebrating this year 20 years of research dedicated to the transcription factor NF-kB. From 1986, the year of its initial identification as a DNA-binding activity for the enhancer of the ... [more ▼]

We are celebrating this year 20 years of research dedicated to the transcription factor NF-kB. From 1986, the year of its initial identification as a DNA-binding activity for the enhancer of the immunoglobulin k light-chain in activated B cells by David Baltimore and colleagues [1] to 2006, almost 20000 papers related to this transcription factor were published, which means three reports per day. This amazing amount of data generated over the years and throughout the world reflects the critical roles played by NF-kB in biology. It is indeed increasingly difficult to find circumstances where NF-kB is not involved at one point. One reason is due to the amazing amount of signals that can activate NF-kB. They include bacterial, viral and fungal products but also inflammatory cytokines, oxidative stress and therapeutically used drugs (as reviewed by Y. Habraken and J. Piette in this issue) and are listed in Tom Gilmore’s website (www.nf-kb.org) (Boston University). Another reason is due to the functional kB sites found in about one hundred genes [2]. These numerous NF-kB target genes play critical roles in cell survival and proliferation, as well as in innate and adaptive immunity, which reflects the essential role of this transcription factor in physiology and diseases. [less ▲]

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See detail20-Nanogold Au20(Td) and Low-Energy Hollow Cages: Void Reactivity
Kryachko, Eugène ULiege; Remacle, Françoise ULiege

in Hogan, P.E.; Brändas, E.J.; Maruani, J. (Eds.) et al Advances in the Theory of Quantum Systems in Chemistry and Physics (2012)

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See detail2003 AZ84: Size, shape, albedo and first detection of topographic features
Dias-Oliveira, Alex; Sicardy, Bruno; Ortiz, Jose-Luis et al

in AAS/Division for Planetary Sciences Meeting Abstracts (2016, October 01)

We analyze two multi-chord stellar occultations by the Trans-Neptunian Object (TNO) 2003 AZ84 observed on February 3, 2012 and November 15, 2014.They provide different elliptical limb fits that are ... [more ▼]

We analyze two multi-chord stellar occultations by the Trans-Neptunian Object (TNO) 2003 AZ84 observed on February 3, 2012 and November 15, 2014.They provide different elliptical limb fits that are consistent to within their respective error bars, but could also suggest a possible precession of the object (assumed here to be a Maclaurin spheroid). The derived equatorial radius and oblateness are R[SUB]e[/SUB] = 393 ± 7 km and ɛ = 0.057 in 2014 and R[SUB]e[/SUB] = 414 ± 13 km and ɛ = 0.165 in 2012, respectively. Those results are consistent with single-chord events observed in January 2011 and December 2013. The figures above provide geometric visual albedos of p[SUB]V(2014)[/SUB] = 0.112 ± 0.008 and p[SUB]V(2012)[/SUB] = 0.114 ± 0.020. Using the Maclaurin assumption, combined with possible rotational periods of 6.67 h and 10.56 h, we estimate density upper limits of 1.89 ± 0.16g/cm[SUP]3[/SUP] and 0.77 ± 0.07g/cm[SUP]3[/SUP] for the two dates, respectively.The 2014 event provides (for the first time during a TNO occultation) a grazing chord with a gradual disappearance of the star behind 2003[SUB]AZ[/SUB]84's limb that lasts for more than 10 seconds. We rule out the possibility of a localized dust concentration as it would imply very high optical depth for that cloud. We favor a local topographic feature (chasm) with minimum width and depth of 22 ± 2.5 km and 7 ± 2.0 km, respectively. Features with similar depths are in fact observed on Pluto's main satellite, Charon, which has a radius of about 605 km, comparable to that of 2003[SUB]AZ[/SUB]84. [less ▲]

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See detailThe 2006 Adjuvant Trastuzumab Convention in Belgium: 5 years later
VANDERHAEGEN, J; PARIDAENS, R; PICCART, M et al

in Cancer Research (2012)

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See detailThe 2006 adjuvant Trastuzumab convention in Belgium: 5 years later
Vanderhaegen, J; Paridaens, R; Piccart, M et al

Poster (2013, March)

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See detail2006, année internationale de la lutte contre la désertification
Ozer, Pierre ULiege

Article for general public (2006)

La désertification est considérée comme l'une des problématiques environnementales les plus préoccupantes du XXIe siècle. Par désertification, on entend la dégradation des terres dans les zones arides ... [more ▼]

La désertification est considérée comme l'une des problématiques environnementales les plus préoccupantes du XXIe siècle. Par désertification, on entend la dégradation des terres dans les zones arides, semi-arides et sub-humides sèches par suite de divers facteurs, parmi lesquels les variations climatiques et les activités humaines. Cette dégradation environnementale affecte directement un milliard d'hectares et menace près de 35 % des terres de la planète ainsi que les moyens de subsistance de deux milliards d'individus. Les estimations des pertes financières mondiales dues à la désertification sont colossales, de l'ordre de 40 milliards d'euros par an. [...] [less ▲]

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See detail2006, International Year of Deserts, Desertification and Dust
Ozer, Pierre ULiege; Courel, Marie-Françoise; Goudie, Andrew S

in Africa Health (2006), 28(4), 3

Desertification ranks among the major environmental challenges of the 21st century and is defined by the United Nations Convention to Combat Desertification as ‘land degradation in arid, semiarid, and dry ... [more ▼]

Desertification ranks among the major environmental challenges of the 21st century and is defined by the United Nations Convention to Combat Desertification as ‘land degradation in arid, semiarid, and dry subhumid areas resulting from various factors, including climatic variations and human activities’. Currently, desertification affects a total area between 6 million and 12 million square kilometres and generates large loss of income, estimated at US$42 billion each year. Areas threatened by desertification occupy 34% of the Earth’s land area and are home to about 2 billion people. [...] [less ▲]

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See detail2006, l'Europe sans boussole
Defossez, Alexandre ULiege; Petit, Nicolas ULiege; Candela, Mercedes

Article for general public (2006)

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See detailThe 2007 rifting event in Northern Tanzania studied by C and L-band interferometry
Oyen, Anneleen; Wauthier, Christelle ULiege; d'Oreye, Nicolas et al

in ECGS Blue Books (2010)

Detailed reference viewed: 38 (1 ULiège)