Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailEffectiveness of PHARMAceutical care for patients with COPD (PHARMACOP): a randomized controlled trial
Tommelein, Eline; Mehuys, Els; Van Hees, Thierry ULg et al

in British Journal of Clinical Pharmacology (2014), 77(5), 756-766

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary ... [more ▼]

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary Disease (COPD) have been conducted. We assessed the effectiveness of a pharmaceutical care program for patients with COPD. METHODS: The PHARMACOP-trial is a single-blind 3-month RCT, conducted in 170 community pharmacies in Belgium, enrolling patients prescribed daily COPD medication, aged >/=50 years, and with a smoking history >/=10 pack-years. A computer-generated randomization sequence allocated patients to intervention (n=371), receiving protocol-defined pharmacist care, or control group (n=363), receiving usual pharmacist care (1:1 ratio, stratified by center). Interventions, focusing on inhalation technique and adherence to maintenance therapy, were carried out at start of the trial and at one month follow-up. Primary outcomes were inhalation technique and medication adherence. Secondary outcomes were exacerbation rate, dyspnea, COPD specific and generic health status and smoking behavior. RESULTS: From December 2010 to April 2011, 734 patients were enrolled. 42 patients (5.7%) were lost to follow-up. At the end of the trial, inhalation score (Mean estimated difference [Delta],13.5%; 95% Confidence Interval [CI], 10.8-16.1; P<.0001) and medication adherence (Delta, 8.51%; 95%CI, 4.63-12.4; P<.0001) were significantly higher in the intervention group compared to the control group. In the intervention group, a significantly lower hospitalization rate was observed (9 vs 35; Rate Ratio, 0.28; 95%CI, 0.12-0.64; P=.003). No other significant between-group differences were observed. CONCLUSION: Pragmatic pharmacist care programs improve the pharmacotherapeutic regime in patients with COPD and could reduce hospitalization rates. [less ▲]

Detailed reference viewed: 39 (16 ULg)
Full Text
Peer Reviewed
See detailEffectiveness of poly(vinylpyridine) block copolymers as stabilizers of aqueous titanium dioxide dispersions of a high solid content
Creutz, Serge; Jérôme, Robert ULg

in Langmuir (1999), 15(21), 7145-7156

Diblock copolymers of 4-vinylpyridine (4VP) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for aqueous dispersions (80 wt % solid) of alumina-coated titanium dioxide. P4VP ... [more ▼]

Diblock copolymers of 4-vinylpyridine (4VP) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for aqueous dispersions (80 wt % solid) of alumina-coated titanium dioxide. P4VP is strongly anchored onto the pigment surface. The molecular composition of the block copolymers has an effect on the amount of copolymer required for imparting good stability to the slurry. Where the two parent triblock copolymers are concerned, triblocks consisting of PMANa outer blocks have a stabilizing efficiency comparable to the diblock copolymers, whereas the reverse structure is much less efficient. In the case of a nonblock distribution of 4VP and MANa in the copolymer chains, the stabilization effect is lost. Finally, the comparison of different stabilizing blocks attached to the same anchoring block confirms that the electrosteric stabilization mechanism is superior to the steric stabilization mechanism. A decrease in the anchoring strength of the diblocks has a deleterious effect on the dispersion stability. [less ▲]

Detailed reference viewed: 23 (1 ULg)
Full Text
Peer Reviewed
See detailEffectiveness of preventive back educational interventions for low back pain: a critical review of randomized controlled clinical trials
Demoulin, Christophe ULg; Marty, M.; Genevay, S. et al

in European Spine Journal (2012), 21

Detailed reference viewed: 10 (0 ULg)
See detailThe effectiveness of tailor made care: the example of cross border care between Belgium and the Netherlands
Fecher-Bourgeois, Fabienne ULg; Paulus, Aggie; van der Made, Jan et al

Report (2000)

The provision of tailor made care, the search for cost containment and European harmonisation and unification have stimulated insurers, providers, patients and governments throughout Europe to seek for ... [more ▼]

The provision of tailor made care, the search for cost containment and European harmonisation and unification have stimulated insurers, providers, patients and governments throughout Europe to seek for opportunities to establish new health care markets. The opening up of cross border care markets presents a good example. These markets offer health care services and products to patients in other countries than the nation which covers their residency or insurance. Although there are clear economic motives for cross border care, the number of patients which actually (can) cross borders is relatively limited: practice proves that current institutional frameworks can block patient flows. This raises the question how and which institutional frameworks have to be present or (re)designed in order to develop and establish an effectively functioning cross border health care market. This paper analyses this question in order to derive lessons and recommendations for future European harmonisation with regard to health care. Using a theoretical framework, which displays the economic motives, obstacles and possible institutional alternatives for cross border care, the conditions for the development and establishment of an effectively functioning health care market between the Netherlands and Belgium is explored. Using cross border care for rheumatological patients as a point of reference, it is shown that current regulations can hinder patients as well as care givers to engage in cross border care. On the basis of our framework, the consumption of Belgians consuming cross border care in the Netherlands is expected to be higher in comparison to the number of Dutch patients who consume care in Belgium. Conflicting interests among private and public specialists, general and academic hospitals, insurance companies and national government policies are also important stumbling blocks for cross border care. Our analysis shows that the most effective institutional frameworks include those that have a functional regional design: they offer the best opportunity to minimize on transaction costs and maximize the degree of tailor made care. [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailThe effectiveness of the Attention Training Technique in reducing intrusive thoughts in schizophrenia: A case study
Levaux, Marie-Noëlle ULg; Laroi, Frank ULg; Offerlin-Meyer, Isabelle et al

in Clinical Case Studies (2011), 10(6), 466-484

The aim of this study was to investigate the effectiveness of the attention training technique (ATT) on the frequency of intrusive thoughts experienced by a person with schizophrenia in her daily life ... [more ▼]

The aim of this study was to investigate the effectiveness of the attention training technique (ATT) on the frequency of intrusive thoughts experienced by a person with schizophrenia in her daily life. The attentional procedure was designed to attenuate self-focused attention and to reinforce attentional control and consisted of auditory external exercises. Homework practice was included to promote transfer to everyday life. The efficacy and specificity of the ATT were assessed with cognitive, functional, and control measures. The impact of ATT on symptomatology, work functioning, and self-esteem was also measured. Postrehabilitation results showed that, after nine training sessions, there was a reduction in intrusive thoughts for the cognitive and ecological outcome measures. Selective attention, attention switching, and resistance to distractive interference specifically improved. The person reported a reduction in intrusive thoughts in her daily life. In addition, positive symptoms decreased. Finally, a 6-month follow-up assessment revealed the maintenance of most of the beneficial effects in daily life. [less ▲]

Detailed reference viewed: 111 (0 ULg)
See detailEffectiveness of the review of individual applications before the European court of Human Rights
Behrendt, Christian ULg

Conference (2011, November 24)

Paper presented at the Round Table Meeting held at the Constitutional Court of Turkey and organized by the Council of Europe, as part of the "Joint Project of the European Union and the Council of Europe ... [more ▼]

Paper presented at the Round Table Meeting held at the Constitutional Court of Turkey and organized by the Council of Europe, as part of the "Joint Project of the European Union and the Council of Europe on Enhancing the Role of the Supreme Judicial Authorities of Turkey in respect of European standards". [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailEFFECTIVENESS OF VOICE THERAPY RELYING ON THE USE OF EUTONY IN THE TRAITEMENT OF DYSPHONIC PATIENTS.
Martinot, Gisèle; Caner, Jessie; Morsomme, Dominique ULg

Poster (2010, July 15)

Twenty six patients with dysphonia (different etiologies) were submitted to a voice therapy program involving the use of Eutony. In order to assess its efficacy, pre and post-treatment audio recordings ... [more ▼]

Twenty six patients with dysphonia (different etiologies) were submitted to a voice therapy program involving the use of Eutony. In order to assess its efficacy, pre and post-treatment audio recordings were analysed and submitted to perceptual rating using GRBAS-I scale and acoustical analysis of fundamental frequency, jitter and shimmer. Aerodynamic data (Maximum Phonation Time & Estimated Subglottic Pressure) were also included in the voice quality assessment protocol. In addition , a questionnaire was sent to all patients to collect self-evaluation of voice quality and therapy outcomes. The study revealed a significant improvement lasting in time for two acoustic parameters : Jitter and Shimmer and five perceptual parameters : Grade, Roughness, Breath, Asthenia and Strain. Aerodynamic data showed slight improvements but no significant changes. Self evaluation questionnaires also tend to strengthen positive effects of therapy. Thus, this study supports the use of Eutony in vocal therapy for dysphonia. Its effects were shown to be measurable with both acoustical analysis and perceptual rating of voice quality. [less ▲]

Detailed reference viewed: 37 (10 ULg)
Full Text
Peer Reviewed
See detailEffectiveness of zoledronic acid in the prevention and treatment of glucocorticoid-induced osteoporosis in men and premenopausal women
Saag, k; Roux, C.; Devogelaer, J. P. et al

in Arthritis and Rheumatism (2010, October), 62(10), 902-903

Detailed reference viewed: 145 (1 ULg)
Peer Reviewed
See detailEffectors of Inflammation in Actinic Prurigo
Arrese, J. E.; Dominguez-Soto, L.; Hojyo-Tomoka, M. T. et al

in Journal of the American Academy of Dermatology (2001), 44(6), 957-61

BACKGROUND: Actinic prurigo is a specific familial photodermatosis of uncertain pathogenesis. OBJECTIVE: Our purpose was to investigate the immunohistologic presentation of actinic prurigo to explore the ... [more ▼]

BACKGROUND: Actinic prurigo is a specific familial photodermatosis of uncertain pathogenesis. OBJECTIVE: Our purpose was to investigate the immunohistologic presentation of actinic prurigo to explore the involved pathomechanisms. METHODS: The present immunohistochemical study was performed on biopsy specimens from 20 Mexican patients presenting with a severe and perennial form of the disease. RESULTS: The dense inflammatory infiltrate was composed predominantly of helper T type 1 lymphocytes admixed with scattered B-cell lymphoid follicles and numerous dermal dendrocytes. Keratinocytes contained abundant tumor necrosis factor-alpha and calprotectin. CONCLUSION: In subjects genetically predisposed to actinic prurigo, ultraviolet light may trigger excessive tumor necrosis factor-alpha production by keratinocytes whose sustained release in turn exerts its proinflammatory activity and deleterious epidermal effects. Such a cascade of events is in line with the therapeutic benefit already reported when thalidomide is used to treat actinic prurigo. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Peer Reviewed
See detailEffects caused on the structure by localised fires in large compartments
Franssen, Jean-Marc ULg; Cajot, Louis-Guy; Schleich, Jean-Baptiste

Conference (1998)

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailEffects de l'entraînement sur la fonction cardio-respiratoire et sur la température rectale chez le poney
Amory, Hélène ULg; Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1988), 132

The influence of training on cardiorespiratory and thermoregulatory adaptations to exercise was studied in 2 healthy race ponies (age : 3.5 and 5 years; weight : 270 and 295 kg). Respiratory airflow (V ... [more ▼]

The influence of training on cardiorespiratory and thermoregulatory adaptations to exercise was studied in 2 healthy race ponies (age : 3.5 and 5 years; weight : 270 and 295 kg). Respiratory airflow (V), tidal volume (VT), electrocardiogram and rectal temperature were simultaneously recorded before, during and alter a standardized exercise which consisted of 3 min walking (1.5 m.sec -1), 3 min slow trotting (3.0 m.sec-1) and 3 min fast trotting (3.5 m.sec-1). These parameters were recorded 4 times, i.e. before (test 1), during (test 2 and 3) and 2 weeks alter (test 4) a 4 week-period of training. Respiratory frequency (f), VT, peak inspiratory and expiratory V, minute volume (Ve), heart rate (H.R.) and rectal temperature changes were calculated on the basis of the collected data. For a given workload, Ve was increased and H.R. decreased during test 2 and 3. These adaptations to training persisted alter the 2 week-period of detraining. Neither Ve nor H.R. recoveries were changed during the whole experimental period. On the other hand, f measured both during exercise and recovery was subject to great variations, obviously independent of the state of training. Lastly, the exercise-induced hyperthermia was reduced alter the training period. This thermoregulatory changes was reversed alter detraining. The results of this preliminary study must be taken with cautions because of the small number of animals used. Nevertheless, they suggested that (1) f is a poor indication of the ventilation, (2) measurements of Ve and HR during a standardized exercise may give a good estimation of the fitness of a horse, (3) on the opposite both parameters measured during recovery seemed to be poorly correlated with the state of training. [less ▲]

Detailed reference viewed: 148 (3 ULg)
Peer Reviewed
See detailEffects of MMP inhibition on emphysema development, Inflammation induced by cadmium in rats
Fievez, Laurence ULg; Kirschvinck, N.; Belleflamme, M. et al

in IUPHAR Congress, Pékin Japon, juillet 2006 (2006)

Detailed reference viewed: 5 (1 ULg)
Full Text
See detailThe effects of 2 levels of energy allowances on growth in captive neonates Testud hermanni boettgeri (Mojsisovic 1889)
Diez, Marianne ULg; Vanstrazeele, B.; Detilleux, Johann ULg et al

in Proceedings du 1er congrès méditerranéen d'herpétologie (2007, April)

Detailed reference viewed: 2 (0 ULg)
Full Text
See detailEffects of 3 months of aerobic training on fitness of Parkinson's disease patients
Demonceau, Marie ULg; rodriguez de la Cruz, carlos; kalimira, kinja et al

in Annals of Physical and Rehabilitation Medicine (2013)

Objectives.– To assess the effects of an aerobic training for people with Parkinson's disease (PD). Methods.– Fourteen patients with Hoehn & Yahr stage [1] < III of PD were allocated to either 3 months of ... [more ▼]

Objectives.– To assess the effects of an aerobic training for people with Parkinson's disease (PD). Methods.– Fourteen patients with Hoehn & Yahr stage [1] < III of PD were allocated to either 3 months of twice-weekly aerobic training (AT group; n = 8), or a control group (C group; n = 6). AT consisted in progressive stationary bike training between 50 and 70% of peak work load (PWL). Maximal incremental test on a cycloergometer was performed before and after rehabilitation. Anxiety, depression and quality of life were assessed using questionnaires. An Anova for repeated measures was used for statistical analysis. Results.– There was a significant “group by time” effect for peak work load (+21% for patients of AT group vs –9% for people of C group). Heart rate 2 minutes after test completion was also significantly decreased in AT group (post hoc analysis, P < 0.01). Patients of AT group also increased their ratio of predicted VO2 peak (+17%) but in a non-significant way. No significant changes in anxiety, depression or quality of life could be highlighted. Conclusions.– This study showed significant improvement of PWL and faster recovery in patients with PD of the AT. Significant effect on VO2 peak could need a more intense training program. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailEffects of 3 months of controlled whole body vibrations with low exposure period on the risk of falls among nursing home residents
Beaudart, Charlotte ULg; Maquet, Didier ULg; Mannarino, Mélanie et al

in Proceeding of the meeting (2013, February 22)

Detailed reference viewed: 37 (22 ULg)
Full Text
Peer Reviewed
See detailEffects of 3 months of short sessions of controlled whole body vibrations on the risk of falls among nursing home residents
Beaudart, Charlotte ULg; Maquet, Didier ULg; Mannarino, Mélanie et al

in BMC Geriatrics (2013), 13(42),

Background: Fatigue, lack of motivation and low compliance can be observed in nursing home residents during the practice of physical activity. Because exercises should not be too vigorous, whole body ... [more ▼]

Background: Fatigue, lack of motivation and low compliance can be observed in nursing home residents during the practice of physical activity. Because exercises should not be too vigorous, whole body vibration could potentially be an effective alternative. The objective of this randomized controlled trial was to assess the impact of 3-month training by whole body vibration on the risk of falls among nursing home residents. Methods: Patients were randomized into two groups: the whole body vibration group which received 3 training sessions every week composed of 5 series of only 15 seconds of vibrations at 30 Hz frequency and a control group with normal daily life for the whole study period. The impact of this training on the risk of falls was assessed blindly by three tests: the Tinetti Test, the Timed Up and Go test and a quantitative evaluation of a 10-second walk performed with a tri-axial accelerometer. Results: 62 subjects (47 women and 15 men; mean age 83.2 ± 7.99 years) were recruited for the study. No significant change in the studied parameters was observed between the treated (n=31) and the control group (n=31) after 3 months of training by controlled whole-body-vibrations. Actually, the Tinetti test increased of + 0.93 ± 3.14 points in the treated group against + 0.88 ± 2.33 points in the control group (p = 0.89 when adjusted). The Timed Up and Go test showed a median evolution of - 1.14 (− 4.75-3.73) seconds in the treated group against + 0.41 (− 3.57- 2.41) seconds in the control group (p = 0.06). For the quantitative evaluation of the walk, no significant change was observed between the treated and the control group in single task as well as in dual task conditions. Conclusions: The whole body vibration training performed with the exposition settings such as those used in this research was feasible but seems to have no impact on the risk of falls among nursing home residents. Further investigations, in which, for example, the exposure parameters would be changed, seem necessary [less ▲]

Detailed reference viewed: 27 (15 ULg)
Full Text
Peer Reviewed
See detailEffects of 3-alkylamino-7-chloro-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides on smooth muscle contractile activity
Ouedraogo, R.; Fontaine, J.; Antoine, M.-H. et al

in Pharmacy and Pharmacology Communications (2000), 6

Detailed reference viewed: 10 (5 ULg)
Full Text
Peer Reviewed
See detailEffects of 4-Hydroxy-2-Nonenal, a Major Lipid Peroxidation-Derived Aldehyde, and N-Acetylcysteine on the Cyclooxygenase-2 Expression in Human Uterine Myometrium.
Temma-Asano, K.; Tskitishvili, Ekaterine ULg; Kanagawa, T. et al

in Gynecologic & Obstetric Investigation (2011)

Background: Chorioamnionitis is one of the important causes of preterm labor. Preterm labor with chorioamnionitis is associated with oxidative stress. We reported that 4-hydroxy-2-nonenal (4-HNE), a major ... [more ▼]

Background: Chorioamnionitis is one of the important causes of preterm labor. Preterm labor with chorioamnionitis is associated with oxidative stress. We reported that 4-hydroxy-2-nonenal (4-HNE), a major end product of oxidative fatty acid metabolism, is accumulated in the placenta with chorioamnionitis. The aim of this study was to confirm the effect of 4-HNE on cyclooxygenase-2 (COX-2) and prostaglandin (PG) induction in the uterine myometrial tissues. We also examined the effect of N-acetylcysteine (NAC) on 4-HNE-induced COX-2 expression. Methods: Uterine myometrial tissues were obtained from 5 patients. One of them underwent elective cesarean section without labor, and 4 of them underwent hysterectomy because of placental previa or atonic bleeding. We stimulated the uterine myometrial tissues with 4-HNE. In addition, the tissues were pretreated with NAC before 4-HNE treatment. The expression of COX-2 mRNA was observed by real-time PCR. PGE2 and prostacyclin release into the supernatants of the tissue cultures was measured by ELISA. Results: 4-HNE induced the COX-2 mRNA expression and PGE2 production in the uterine myometrial tissue culture in a dose-dependent and time-dependent manner. NAC inhibited 4-HNE-induced COX-2 expression. Conclusion: 4-HNE may play an important role in preterm labor. NAC might be protective against preterm labor under oxidative stress. [less ▲]

Detailed reference viewed: 11 (1 ULg)