Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailDevelopment of a sustained release bolus for lambs
Evrard, Brigitte ULg; Dechesne, Jean-Paul; Fagetton, Xavier et al

Conference (1990, March)

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailDevelopment of a sustained release bolus for sheep : "in vitro" and "in vivo" results
Evrard, Brigitte ULg; Dechesne, Jean-Paul; Fagetton, Xavier et al

in Proceedings of 19th International Symposium on controlled release of Bioactive Materials (1992)

Detailed reference viewed: 5 (2 ULg)
See detailDevelopment of a technique to measure 17β-estradiol in discrete brain regions in zebra finch
Charlier, Thierry ULg; Po, Kelvin WL; Shah, Amit H et al

Poster (2008)

Detailed reference viewed: 10 (1 ULg)
See detailDevelopment of a test battery for assessing cognitive functions of elderly patients with Down syndrome
Georges, Michel ULg; Thewis, B.; Van der Linden, Martial ULg et al

in Revue de Neuropsychologie (2001), 11(4), 549-579

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess ... [more ▼]

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess several domains of cognition was administered to a group of 12 DS individuals older than 35 years. It proved sensitive to individual differences and thus appears to be appropriate for the observation of cognitive change linked to age. Statistical analyses do not reveal cognitive changes in the DS subjects after one year time. However qualitative analyses of individual profiles suggest a cognitive decline in one subject. Additionally, in a PET-scan examination, three subjects present a mild decrease in cerebral glucose metabolism similar to that usually observed in AD. An AD diagnostic though remains uncertain at this stage. [less ▲]

Detailed reference viewed: 134 (9 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a test to assess the Banana Bunchy Top Virus transmissibility through direct analysis of its aphid vector Pentalonia nigronervosa
De Clerck, Caroline ULg; Francis, Frédéric ULg; Lepoivre, Philippe ULg et al

in Communications in Agricultural and Applied Biological Sciences (2013), 78(1), 49-54

Detailed reference viewed: 93 (27 ULg)
See detailDevelopment of a thorax CT-scan based finite element model for thoracic injury assessment
Nsiampa, Nestor; D'Otreppe, Vinciane ULg; Robbe, Cyril ULg et al

Conference (2011, November 14)

Detailed reference viewed: 48 (7 ULg)
Peer Reviewed
See detailDevelopment of a translation stage for in situ non-invasive analysis and high resolution imaging
Strivay, David ULg; Clar, Mathieu ULg; Rakkaa, Saïd ULg et al

Poster (2016, March)

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems ... [more ▼]

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems have been developed and optimized. Nonetheless, these instruments are usually used with a tripod or a manual position system. This is very time consuming when performing point analysis or 2D scanning of a surface. The Centre Européen d’Archéométrie (CEA) has build a translation system made of pluggable rails of 1 m long with a maximum length and height of 3 m. Three motors embedded in the system allow the platform to be moved along these axis, toward and backward from the sample. The rails hold a displacement system, providing a continuous movement. Any position can be reached with a reproducibility of 0.1 mm. The displacements are controlled by an Ethernet connection through a laptop computer running a multiplatform homemade software written in JAVA. This software allows a complete control over the positioning using a simple, unique, and concise interface. Automatic scanning can be performed over a large surface of 3 meters on 3 meters. The Ethernet wires provide also the power for the different motors and, if necessary the detection head. The platform has been originally designed for a XRF detection head (with its full power alimentation) but now can accommodate many different systems like IR reflectography, digital camera, hyperspectral camera, Raman probes, etc. The positioning system can be modified to combine the acquisition software of the imaging or analytical techniques and the positioning software. [less ▲]

Detailed reference viewed: 39 (6 ULg)
Full Text
See detailDevelopment of a transmission model of Murid herpesvirus 4
François, Sylvie ULg

Doctoral thesis (2012)

Gammaherpesviruses are the archetype of persistent viruses that have been identified in a series of animals ranging from mice to man. To date the study of transmission of these viruses in natural ... [more ▼]

Gammaherpesviruses are the archetype of persistent viruses that have been identified in a series of animals ranging from mice to man. To date the study of transmission of these viruses in natural condition has been limited by the fact that no experimental transmission model exists. Establishment and characterization of a model of transmission are therefore critical points to evaluate strategies of interference with the epidemiological cycle of gammaherpesviruses. We are studying Murid herpesvirus 4 (MuHV-4) which has originally been isolated from naturally infected bank voles (Myodes glareolus). Although serological data indicate that closely related strains are present in wood mice (Apodemus sylvaticus) and domestic mice (Mus musculus), no experimental transmission of MuHV-4 has been demonstrated in laboratory mice, the classically used in vivo model. The objective of this work was therefore to fill this gap. In a first study, we performed a comparative characterization of the infection by MuHV-4 in mice and bank voles. Our results showed that the infectious process, the pathology and the latency establishment are similar in the two species, even if replication is quantitatively lower in bank voles than in mice. It therefore appeared that, Mus musculus represents a suitable host for studying gammaherpesvirus pathogenesis with MuHV-4. These results have been published in Journal of General Virology (J Gen Virol. 2010 Oct;91(Pt 10):2553-63). In a second study, thanks to in vivo imaging, we have been able to observe, for the first time, transmission of MuHV-4 in mice. We firstly showed that MuHV-4 reexcretion occurs in the genital tract of female mice at a period by which latency is considered as established. Ex vivo imaging, histology and PCR allowed us to demonstrate the presence of viral genomes in vaginal tissues and to localize viral replication at the external border of the vagina. We also demonstrated the transient and repetitive presence of infectious viruses in the vaginal cavity. Secondly, we demonstrated the implication of sexual steroid hormones in this re-excretion process. Indeed, we analyzed the infection of untreated mice, ovariectomized mice and ovariectomized mice complemented with estrogens and/or progesterone. These analyses revealed a positive role of estrogens in the observed re-excretion. Finally, based on these results, we tested MuHV-4 transmission in mice by creating different epidemiological conditions. In the conditions tested, vertical transmission did not occur, nor did horizontal transmission between individuals of the same gender. In contrast, we were able to observe sexual transmission to naïve males by serology, in vivo imaging and quantitative PCR. In conclusion, this work has on one hand demonstrated the quality of mice as an in vivo model for MuHV-4 studies and, on the other, it has shown for the first time the existence of re-excretion and sexual transmission of MuHV-4 amongst laboratory mice. The results of this work should therefore have implications for the study of gammaherpesviruses, but also more generally for the study of sexually transmissible infections. [less ▲]

Detailed reference viewed: 107 (28 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a two-color picosecond optical parametric oscillator, pumped by a Nd:YAG laser mode locked using a nonlinear mirror, for doubly-resonant sum frequency generation spectroscopy
Mani, A. A.; Dreesen, Laurent ULg; Humbert, C. et al

in Surface Science (2002), 502-503

We step up a doubly-resonant sum frequency generation (DR-SFG) spectrometer based on the use of an all-solid-state flash-lamp-pumped Nd:YAG laser that synchronously pumps two parametric oscillators ... [more ▼]

We step up a doubly-resonant sum frequency generation (DR-SFG) spectrometer based on the use of an all-solid-state flash-lamp-pumped Nd:YAG laser that synchronously pumps two parametric oscillators. Pulses as short as 12 ps FWHM are generated by mode locking a Nd:YAG oscillator using a frequency doubling nonlinear mirror combined with a two-photon absorber. The available pump power is shared between a LiNbO3/AgGaS2 optical parametric oscillator (OPO), tunable from 3800 to 1100cm-1 and a BBO OPO tunable from 410 to 2600 nm. Spectral resolution and pulse are 2 and 3 cm-1 in the infrared and visible spectral ranges, respectively. First DR-SFG spectra of self-assembled monolayers on Au are presented. [less ▲]

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a universal microarray based on the ligation detection reaction and 16S rRNA gene polymorphism to target diversity of cyanobacteria
Castiglioni, Bianca; Rizzi, Ermann; Frosini, Andrea et al

in Applied and Environmental Microbiology (2004), 70(12), 7161-7172

The cyanobacteria are photosynthetic prokaryotes of significant ecological and biotechnological interest, since they strongly contribute to primary production and are a rich source of bioactive compounds ... [more ▼]

The cyanobacteria are photosynthetic prokaryotes of significant ecological and biotechnological interest, since they strongly contribute to primary production and are a rich source of bioactive compounds. In eutrophic fresh and brackish waters, their mass occurrences (water blooms) are often toxic and constitute a high potential risk for human health. Therefore, rapid and reliable identification of cyanobacterial species in complex environmental samples is important. Here we describe the development and validation of a microarray for the identification of cyanobacteria in aquatic environments. Our approach is based on the use of a ligation detection reaction coupled to a universal array. Probes were designed for detecting 19 cyanobacterial groups including Anabaena/Aphanizomenon, Calothrix, Cylindrospermopsis, Cylindrospermum, Gloeothece, halotolerants, Leptolyngbya, Palau Lyngbya, Microcystis, Nodularia, Nostoc, Planktothrix, Antarctic Phormidium, Prochlorococcus, Spirulina, Synechococcus, Synechocystis, Trichodesmium, and Woronichinia. These groups were identified based on an alignment of over 300 cyanobacterial 16S rRNA sequences. For validation of the microarrays, 95 samples (24 axenic strains from culture collections, 27 isolated strains, and 44 cloned fragments recovered from environmental samples) were tested. The results demonstrated a high discriminative power and sensitivity to 1 fmol of the PCR-amplified 16S rRNA gene. Accurate identification of target strains was also achieved with unbalanced mixes of PCR amplicons from different cyanobacteria and an environmental sample. Our universal array method shows great potential for rapid and reliable identification of cyanobacteria. It can be easily adapted to future development and could thus be applied both in research and environmental monitoring. [less ▲]

Detailed reference viewed: 46 (10 ULg)
See detailDevelopment of a version of GeoPEARL for the Walloon region of Belgium
Bah, Boubacar Billo ULg; Vanclooster, Marnik; Oger, Robert ULg

Scientific conference (2009, November)

Detailed reference viewed: 23 (0 ULg)
Full Text
Peer Reviewed
See detailDevelopment Of A Visual Method To Quantify The Gossypol Content In Cotton Seeds
Benbouza, H.; Lognay, Georges ULg; Palm, Rodolphe ULg et al

in Crop Science (2002), 42(6), 1937-1942

Detailed reference viewed: 39 (6 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a waste heat recovery orc prototype using an oil-free scroll expander
Declaye, Sébastien ULg; Quoilin, Sylvain ULg; Lemort, Vincent ULg

Conference (2011, September 22)

The world is facing a historical increase in energy demand and energy consumption. As consequence the conventional fossil fuels are depleting faster with an inherent pollution causing severe damages to ... [more ▼]

The world is facing a historical increase in energy demand and energy consumption. As consequence the conventional fossil fuels are depleting faster with an inherent pollution causing severe damages to our environment. Renewable energy sources are considered as a solution to both environmental issue and energy demand. At the same time a lot of waste heat is witnessed in processes in industries. Our objective is to contribute to the development of ORC systems, that appear to us as a good solution to recover this wasted heat. In such waste heat applications, depending on the heat source flow rate and temperature, electrical power output can be as low as a few kilowatts. In this power range, there is no cost effective expansion machine available on the market. On existing prototypes, expansion devices are usually retrofitted volumetric compressors originally designed for refrigeration or air compression applications. Air compressors have the advantage to handle higher inlet temperature but tightness is often an issue in ORC application since the fluids used have a non negligible environmental impact. This paper presents the development of a small-scale WHR ORC unit at the Thermodynamic Laboratory of the University of Liège: the prototype uses a scroll expander, plate heat exchangers, a diaphragm piston pump and a liquid receiver. This system was tested with different working fluids (R123, R245fa and HFE7000) and a thermal efficiency close to 8% was obtained for a net output power of about 2 kWe. The specificity of the proposed prototype is the absence of lubrication: in order to avoid oil circulation in the ORC loop, an oil-free scroll expander is developed. This expander is originally an air scroll compressor that was modified using a magnetic coupling to ensure tightness. The experimental results highlight the good efficiency of the device, despite a relatively high internal leakage due to absence of lubrication. The necessity of using magnetic coupling is also justified by comparing the experimental results with previous ones obtained using mechanical sealing. [less ▲]

Detailed reference viewed: 165 (6 ULg)
Full Text
Peer Reviewed
See detailDevelopment of adenocarcinoma in chronic fistula in Crohn's disease
Laurent, Stanislas; Barbeaux, A.; Detroz, Bernard ULg et al

in Acta Gastro-Enterologica Belgica (2005), 68(1, Jan-Mar), 98-100

The authors report the case of a 55 yr-old woman suffering from Crohn's disease since 31 years with stricture and fistulas developed in the ileocolic junction and anorectal portion. Long-standing ... [more ▼]

The authors report the case of a 55 yr-old woman suffering from Crohn's disease since 31 years with stricture and fistulas developed in the ileocolic junction and anorectal portion. Long-standing anorectal fistulas and stricture led to adenocarcinoma and finally fistulisation in the vagina. Diagnosis was made by perineal examination with biopsies under general anaesthesia. Treatment was first posterior pelvectomy with resection of the anterior wall of vagina. Secondarily, radiochemotherapy was administrated. The authors discuss the incidence and risk factors of carcinoma in Crohn's disease with chronic fistulas. [less ▲]

Detailed reference viewed: 76 (4 ULg)
Full Text
See detailDevelopment of Advanced Driver Assistance Systems by means of the traffic flow simulation tool PELOPS with HiL-functionalities
Christen, Fréderic ULg; Benmimoun, A.; Breuer, K. et al

in Berechnung und Simulation im Fahrzeugbau (2004, September 29)

During the last years a rapid increase of traffic volume in association with limited road space could be observed. This led to a raising load of the driver while achieving his driving tasks. Therefore so ... [more ▼]

During the last years a rapid increase of traffic volume in association with limited road space could be observed. This led to a raising load of the driver while achieving his driving tasks. Therefore so called Advanced Driver Assistance Systems (ADAS) are under development in recent years with an upward tendency. Such systems will relieve the driver and improve safety on the road in the future. A rising number of computed-aided-simulation becomes important for the development and evaluation of such systems. Developing ADAS makes a specific demand on the simulation environment. ADAS interact strongly with their traffic environment. Therefore the simulation has to cover both, a detailed model of the ego vehicle and an adequate representation of the traffic environment. The traffic flow simulation program PELOPS meets these requirements. The newly implemented extension of PELOPS with techniques of Software- and Hardware-in-the-Loop-simulation (SiL- and HiL-simulation) allows system developers a fast functional check and an assessment of new ADAS. External software can be linked to PELOPS via Ethernet-based network communication, which has already been realised for the widely used development tool MATLAB/Simulink. Besides the Ethernet interface PELOPS-HiL (PHIL) gives the developer two other possibilities for providing a HIL-environment: a serial interface which can be used for a connection to a dSpace development platform and a CAN data bus interface. The following article describes by means of chosen examples how flexible the PHIL-simulation can be adapted to a development task and which results can be obtained. [less ▲]

Detailed reference viewed: 33 (1 ULg)