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See detailDevelopment of a biomechanical model of deer antler cancellous bone based on X-ray microtomographic images
de Bien, Charlotte ULg; Mengoni, Marlène ULg; D'Otreppe, Vinciane ULg et al

in Micro-CT User Meeting 2012 - Abstract Book (2012, April)

Finite element models accurately compute the mechanical response of bone and bone-like materials when the models include their detailed microstructure. The aim of this paper is to develop and validate a ... [more ▼]

Finite element models accurately compute the mechanical response of bone and bone-like materials when the models include their detailed microstructure. The aim of this paper is to develop and validate a biomechanical model for deer antler cancellous bone tissue based on X-ray microtomographic images. In order to simulate the mechanical behavior under compressive load using a finite element model, images obtained by X-ray microtomography were exported into Metafor, which is an non-linear finite element software initially developed at University of Liège for metal forming processes. This software has recently found biomedical applications. The ultimate goal is to compare model predictions with the mechanical behavior observed experimentally using the Skyscan material testing stage under compression mode. The creation of the biomechanical model mesh from segmented μCT images, its integration into the software Metafor and the simulation of a compression test are described in this paper. [less ▲]

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See detailDevelopment of a biotransformation process of hydroperoxides into green leaf volatiles using sugar beet leaves
Gigot, C.; Ongena, Marc ULg; Fauconnier, Marie-Laure ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010)

Natural green leaf volatiles (GLVs) are commonly sole AS aldehydic and alcoholic flavors; their synthesis is a great challenge for industry. Especially, the bioconversion step of fatty acid hydroperoxides ... [more ▼]

Natural green leaf volatiles (GLVs) are commonly sole AS aldehydic and alcoholic flavors; their synthesis is a great challenge for industry. Especially, the bioconversion step of fatty acid hydroperoxides into aldehydes by the hydroperoxide lyase (HL). This widely studied enzyme is present in cell membranes of green organs from superior plants. Extracted from its natural condition, HL is subject to a suicidal behavior, being irreversibly inhibited by its own substrate. Furthermore, GLVs produced are highly volatile and quickly degraded by other plant enzymes. Thence, high GLVs levels in industrial production are very difficult to obtain, but several biotechnological tools could be developed to enhance this natural synthesis level more than hundred times. This paper will describe a new method for GLVs production in bioreactor using sugar beet leaves as source of HL. One step reaction, including hydroperoxide metabolisation and GLVs extraction, is performed during a short time process. Downstream processing to dispose of natural and pure GLVs molecule will also be discussed. [less ▲]

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See detailDevelopment of a biotransformation process of hydroperoxydes into green leaf volatiles using sugar beet leaves.
Gigot, C.; Ongena, Marc ULg; Fauconnier, Marie-Laure ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14 (S2)

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See detailDevelopment of a bronchoreactivity test in dogs
Clercx, Cécile ULg; Dufour, P.; Gustin, Pascal ULg

in 6th IVENTA Meeting - Pre-congress-dayof the XVII SWAVA World Congress - Rome - Italie (1992)

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See detailDEVELOPMENT OF A CAPE-OPEN 1.0 SOCKET
Radermecker, Eric; Wising, Ulrika; Dumont, Marie-Noëlle ULg

Conference (2008, November)

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See detailDevelopment of a CELestial Infrared Nuller Experiment (CELINE) for broadband nulling and new single-mode fiber testing
Hanot, Charles ULg; Riaud, Pierre; Mawet, Dimitri et al

in Danchi, W. C.; Delpancke, F.; Rajagopal, J. K. (Eds.) Optical and Infrared Interferometry II (2010, July)

he small angular distance (<100 mas) and the huge flux ratio (107) between an Earth-like exoplanet in the socalled habitable zone and its host star makes it very difficult to direct image such systems ... [more ▼]

he small angular distance (<100 mas) and the huge flux ratio (107) between an Earth-like exoplanet in the socalled habitable zone and its host star makes it very difficult to direct image such systems. Nulling interferometry consists of a very powerful technique that combines destructively the light from two or more collectors to dim the starlight and to reveal faint companions in its vicinity. We have developed a new nulling experiment based on the fiber nuller principle. This fully symmetric reflective nulling bench aims at testing broadband nulling in both H and K bands as well as characterizing photonic fibers for modal filtering. We present in this paper the design, the development as well as preliminary results of the experiment. [less ▲]

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See detailDevelopment of a chemiotherapy protocol to sanitise banana genotypes infected by banana mild mosaic virus (BanMMV)
Busogoro, J. P.; Vandermolen, M.; Masquelier, L. et al

Conference (2006)

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See detailDevelopment of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration.
Tchemtchoua Tateu, Victor ULg; Atanasova, G.; Aqil, Abdelhafid ULg et al

in Biomacromolecules (2011), 12

The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant ... [more ▼]

The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant cutaneous resident cells. Three-dimensional chitosan nanofibrillar scaffolds produced by electrospinning were compared with evaporated films and freeze-dried sponges for their biological properties. The nanofibrillar structure strongly improved cell adhesion and proliferation in vitro. When implanted in mice, the nanofibrillar scaffold was colonized by mesenchymal cells and blood vessels. Accumulation of collagen fibrils was also observed. In contrast, sponges induced a foreign body granuloma. When used as a dressing covering full-thickness skin wounds in mice, chitosan nanofibrils induced a faster regeneration of both the epidermis and dermis compartments. Altogether our data illustrate the critical importance of the nanofibrillar structure of chitosan devices for their full biocompatibility and demonstrate the significant beneficial effect of chitosan as a wound-healing biomaterial. [less ▲]

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See detailDevelopment of a clinical assessment tool in identifying Asian men with low bone mineral density and comparison of its usefulness to quantitative bone ultrasound
Kung, A. W. C.; Ho, A. Y. Y.; Ross, P. D. et al

in Osteoporosis International (2005), 16(7), 849-855

Osteoporosis in men is a largely neglected condition in Asia (and elsewhere), despite the fact that one-third of hip fractures occur in men. Moreover, access to bone mineral density (BMD) measurements is ... [more ▼]

Osteoporosis in men is a largely neglected condition in Asia (and elsewhere), despite the fact that one-third of hip fractures occur in men. Moreover, access to bone mineral density (BMD) measurements is limited in many areas of Asia, and inexpensive methods of targeting high risk patients for BMD measurements would be valuable. We have developed a simple clinical assessment tool to identify high risk Asian men for BMD measurements. Information on risk factors was collected from 420 community-dwelling adult Chinese men aged 50 years and above using a structured questionnaire, and the ability of these risk factors to identify subjects with femoral neck BMD T score <= -2.5 was assessed. Multiple regression analysis and item reduction yielded a final clinical risk assessment tool based on only age and weight, similar to the Osteoporosis Self-assessment Tool for Asians (OSTA), described previously for Asian women. The OSTA values of <= -1 had a sensitivity of 81% and specificity of 66%, and the area under the receiver operating characteristics curve was 0.83. The index was validated in another sample of 356 men with a sensitivity of 82% and specificity of 67 %, and an AUC of 0.85. The usefulness of OSTA was further compared to calcaneal quantitative bone ultrasound (QUS) in the validation sample of 356 men. The optimal cutoff T score of -1.2 for QUS yielded sensitivity and specificity values of 75 and 67%, respectively. The AUC for QUS was 0.79. Combining OSTA and QUI gave a sensitivity of 88% and specificity of 66% to identify men with low BMD at the femoral neck, and an AUC of 0.86 which was statistically not different from either OSTA or QUI alone. We conclude that OSTA is a simple and effective clinical risk assessment tool for identifying not only female but also male subjects at increased risk of osteoporosis, and its use could facilitate the appropriate and more cost-effective use of bone densitometry in developing countries. [less ▲]

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See detailDevelopment of a colorimetric method for the dosage of OI- anions and I2 in aqueous media
Bafort, Françoise ULg; Barthelemy, Jean-Paul ULg; Parisi, Olivier ULg et al

in Communications in Agricultural and Applied Biological Sciences (2014), 79(1), 155-160

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See detailDevelopment of a combined mechanical and enzymatic method for the isolation of intact preantral follicles from fetal, calf and adult bovine ovaries
Figueiredo, José Ricardo; Hulshof, S. C. J.; Van den Hurk, R. et al

in Theriogenology (1993), 40(4), 789-799

The isolation of preantral follicles from the ovaries of bovine fetuses, calves and adult cows was performed using a simple, rapid mechanical and enzyme method. The ovaries were cut into small pieces with ... [more ▼]

The isolation of preantral follicles from the ovaries of bovine fetuses, calves and adult cows was performed using a simple, rapid mechanical and enzyme method. The ovaries were cut into small pieces with a tissue chopper. Then, the suspension was filtered successively through 500 and 100 μm nylon mesh filters. This simple mechanical procedure resulted in large numbers of isolated preantral follicles: 2,142 ± 254; 512 ± 92 and 298 ± 54 from the ovaries of bovine fetuses, calves and cows, respectively. In addition, the ovarian fragments between 100 and 500 μm were suspended in 10 ml of M199 Hepes medium plus 5% FCS and divided into 2 equal parts: one portion was used for collagenase treatment (200 U/ml) for 20 minutes, while the other served as a control. Collagenase treatment resulted in 841 ± 161; 216 ± 51 and 52 ± 17 preantral follicles from fetuses, calves and cows, respectively, compared with 312 ± 86; 52 ± 15 and 10 ± 2 in the control group. The use of collagenase with ovarian fragments selected by filtration as a method for increasing the rate of recovery of preantral follicles is described here. [less ▲]

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See detailDevelopment of a compact single room ventilation unit with heat recovery dedicated to tertiary buildings
Gendebien, Samuel ULg; Martens, Jonathan; Prieels, Luc et al

Conference (2015)

In the frame of the European project called Bricker, a new prototype of single room ventilation with heat recovery has been developed. This new unit is supposed to be installed in class rooms of an ... [more ▼]

In the frame of the European project called Bricker, a new prototype of single room ventilation with heat recovery has been developed. This new unit is supposed to be installed in class rooms of an educational institution. This paper deals with the development of the first prototype of this unit. An empirical model of such device is also proposed in order to be coupled with a building model. This aims at determining the seasonal performance of the device and thus the potential energy saving (compared to other technologies) resulting from its use. The first part of the paper presents the specifications and the final characteristics of the developed device. In this context, a by-pass for free cooling in summer conditions as well as the strategies under frosting conditions are described. Secondly, the coefficient of performance (COP) of such device is recalled. In the early stage of the development process, the COP is determined based on the manufacturer data of the heat recovery exchanger and the fans. The coupling between fan curve and the predicted hydraulic performance of the unit allows for determining a first approximation of the fans electrical consumption for several delivered flow rates. The third part of the paper focuses on the experimental investigations carried out in order to determine the flow rate really delivered by the unit. Electrical consumptions of several flow rates are also measured in order to characterize the COP of the unit in those conditions. Finally, a comparison between the measured and the predicted performance based on manufacturer data has been realized in terms of COP. A performance map based on experimental results is proposed in order to be coupled with a building model. [less ▲]

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See detailDevelopment of a compartment model based on CFD simulations for mixing description in bioreactors
Delafosse, Angélique ULg; Delvigne, Frank ULg; Collignon, Marie-Laure ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14(2), 517-522

Understanding and modelling the complex interactions between biological reaction and hydrodynamics is a key problem when dealing with bioprocesses. It is fundamental to be able to accurately predict the ... [more ▼]

Understanding and modelling the complex interactions between biological reaction and hydrodynamics is a key problem when dealing with bioprocesses. It is fundamental to be able to accurately predict the hydrodynamics behaviour of bioreactors of different size and its interaction with the biological reaction. CFD can provide detailed modelling about hydrodynamics and mixing. However, it is computationally intensive, especially when reactions are taken into account. Another way to predict hydrodynamics is the use of "Compartment" or "Multi-zone" model which are much less demanding in computation time than CFD. However, compartments and fluxes between them are often defined by considering global quantities not representative of the flow. To overcome the limitations of these two methods, a solution is to combine compartment modelling and CFD simulations. Therefore, the aim of this study is to develop a methodology in order to propose a compartment model based on CFD simulations of a bioreactor. The flow rate between two compartments can be easily computed from the velocity fields obtained by CFD. The difficulty lies in the definition of the zones in such a way they can be considered as perfectly mixed. The creation of the model compartments from CFD cells can be achieved manually or automatically. The manual zoning consists in aggregating CFD cells according to the user's wish. The automatic zoning defines compartments as regions within which the value of one or several properties are uniform with respect to a given tolerance. Both manual and automatic zoning methods have been developed and compared by simulating the mixing of an inert scalar. For the automatic zoning, several algorithms and different flow properties have been tested as criteria for the compartment creation. [less ▲]

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See detailDevelopment of a contact model adapted to incremental forming
Henrard, Christophe ULg; Bouffioux, Chantal ULg; Godinas, A. et al

in Banabic, D. (Ed.) Proceedings of the 8th ESAFORM Conference on Material Forming (2005)

The objective of this article is to present the development of a new method for taking into account the contact between the tool and the blank during incremental forming. First, the need for such a model ... [more ▼]

The objective of this article is to present the development of a new method for taking into account the contact between the tool and the blank during incremental forming. First, the need for such a model is justified. Then, the basic features of the adapted dynamic explicit scheme are presented, followed by the new algorithms proposed and their programming. Finally, some conclusions and perspectives are drawn. [less ▲]

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See detailDevelopment of a cost calculation module for the inland and sea-river waterway transport
Marchal, Jean ULg; Kicheva, D.

in Proceedings of the PIANC Conference on Inland and Maritime navigation and Coastal Problems of East European Countries (1996, September)

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See detailDevelopment of a Cough Induction Test in Pigs: Effects of Sr 48968 and Enalapril
Moreaux, B.; Beerens, Dominique ULg; Gustin, Pascal ULg

in Journal of Veterinary Pharmacology & Therapeutics (1999), 22(6), 387-389

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See detailDevelopment of a coupled flow and transport 3D model for simulating seawater intrusions in coastal aquifers
Carabin, Guy; Dassargues, Alain ULg

in Natuurwetenschappelijk Tijdschrift (1999), 79

Detailed reference viewed: 27 (5 ULg)