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See detailEffects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens.
Swennen, Quirine; Geraert, Pierre-Andre; Mercier, Yves et al

in The British journal of nutrition (2011), 106(12), 1845-54

Besides its typical role as an amino acid in protein synthesis, methionine is an important intermediate in methylation reactions. In addition, it can also be converted to cysteine and hence plays a role ... [more ▼]

Besides its typical role as an amino acid in protein synthesis, methionine is an important intermediate in methylation reactions. In addition, it can also be converted to cysteine and hence plays a role in the defence against oxidative stress. The present study was conducted to investigate further the role of DL-methionine (DLM) and its hydroxy analogue, DL-2-hydroxy-4-methylthiobutanoic acid (DL-HMTBA), on zootechnical performance and oxidative status of broiler chickens. Male broiler chickens were reared on two diets differing in crude protein (CP) content (low-protein, 18.3 % v. high-protein, 23.2 % CP) and were supplemented either with 0.25 % DLM or 0.25 % DL-HMTBA. Reducing the dietary protein content resulted in an impaired body weight gain (P < 0.0001). However, supplementation of DL-HMTBA to the low-protein diet partially alleviated these negative effects (P = 0.0003). This latter phenomenon could be explained by the fact that chickens fed DL-HMTBA-supplemented diets displayed a better antioxidant status as reflected in lower lipid peroxidation probably as a consequence of their higher hepatic concentrations of total and reduced glutathione compared with their DLM counterparts. On the other hand, within the high protein levels, uric acid might be an important antioxidant to explain the lower lipid peroxidation of high-protein DL-HMTBA-supplemented chickens. Hepatic methionine sulfoxide reductase-A gene expression was not significantly affected by the dietary treatments. In conclusion, the present study indicates that there are interactions between dietary protein content and supplementation of methionine analogues with respect to broiler performance and antioxidant status, also suggesting a causal link between these traits. [less ▲]

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See detailEffects of dietary supplementation of methionine and its hydroxy analog DL-2-hydroxy-4-methylthiobutanoic acid on growth performance, plasma hormone levels, and the redox status of broiler chickens exposed to high temperatures.
Willemsen, H.; Swennen, Q.; Everaert, Nadia ULg et al

in Poultry science (2011), 90(10), 2311-20

Heat stress is known to impair performance and to induce oxidative stress in poultry. The aim of the present study was to compare the effects of dietary supplementation of dl-methionine (dl-M) or the ... [more ▼]

Heat stress is known to impair performance and to induce oxidative stress in poultry. The aim of the present study was to compare the effects of dietary supplementation of dl-methionine (dl-M) or the synthetic analog 2-hydroxy-4-methylthiobutanoic acid (dl-HMTBA) on broiler growth performance, plasma hormone levels, and some oxidative stress-related parameters under conditions of chronic exposure to high temperatures (HT). From 2 to 6 wk of age, male broiler chickens were reared under either a constant temperature of 32 degrees C until 6 wk of age or a normal temperature scheme (gradual decrease to 18 degrees C at 5 wk of age). Chicks in both the normal and HT treatments were provided with a commercial grower diet supplemented with either 1.0 or 1.2 g/kg of dl-M or 1.0 or 1.2 g/kg of dl-HMTBA. Because there were no effects of supplement dose, data were pooled over both doses within each temperature treatment. The chronic HT treatment impaired feed intake and BW gain, but these negative effects were less pronounced when the chickens received dl-HMTBA. Exposure to HT was also associated with decreased (P < 0.001) plasma thyroid hormones and increased (P < 0.0001) plasma corticosterone levels. At 4 wk of age, and irrespective of the supplemental source, chickens subjected to HT were characterized by significantly lower plasma TBA-reactive substance levels. In contrast, at 6 wk of age, plasma TBA-reactive substance levels were significantly increased by HT, but this effect was observed only for the chickens receiving dl-M and not for those receiving dl-HMTBA. High temperatures induced a significant increase in hepatic total glutathione (GSH) and oxidized GSH levels, regardless of the supplemental source. However, the hepatic ratios of reduced GSH to total GSH and reduced GSH to oxidized GSH were highest in chickens supplemented with dl-HMTBA. In conclusion, dl-HMTBA supplementation partially prevented the growth-depressing effects of chronic heat exposure compared with dl-M supplementation. It can be inferred that dl-HMTBA is more efficient in alleviating HT-induced oxidative damage because of a more favorable reduced GSH-to-total GSH ratio. [less ▲]

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See detailEffects of different calcium formulations on calcium absorption in healthy volunteers
Reginster, Jean-Yves ULg; DEROISY, Rita ULg; Franchimont, P

in Advances in Therapy (1991), 8(2), 86-91

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See detailEffects of different levels of energy allowances and of hibernation on growth in hatchling Testudo hermanni boettgeri (Mojsisovic, 1889)
Diez, Marianne ULg; Vanstrazeele, Boris; Justet, Delphine et al

in Clauss, M.; Fidgett, A.; Hatt, J. M. (Eds.) et al Zoo Animal Nutrition IV (2009)

Cet article présente des données de croissance de Testudo nouveaux nés dont les apports alimentaires et l'hibernation ont été contrôlés.

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See detailEffects of different periods of feed restriction before compensatory growth on performance in Belgian Blue bulls
Hornick, Jean-Luc ULg; Clinquart, Antoine ULg; Van Eenaeme, Christian ULg et al

in EAAP (Ed.) Abstracts of the 47th meeting of the European Association for Animal Production (1996)

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See detailEffects of different spatial interpolators on the estimate of extreme precipitations
Ly, Sarann ULg; Beckers, Eléonore ULg; Charles, Catherine ULg et al

in Geophysical Research Abstracts (2011), 13

The design values of the areal precipitation are needed for engineer to manage vital elements of our infrastructure. The areal precipitation can be generated by different interpolation methods. The ... [more ▼]

The design values of the areal precipitation are needed for engineer to manage vital elements of our infrastructure. The areal precipitation can be generated by different interpolation methods. The problem involves choosing the interpolation method that we should use to estimate the extreme event. This work aimed at analyzing the effects of different interpolation methods on the estimate of extreme events of daily areal precipitations at catchment scale. The extreme rainfalls were estimated using areal daily rainfall interpolated by several interpolation methods (Thiessen polygon, Inverse Distance Weighting, Ordinary Kriging, Universal Kriging, Kriging with an External Drift and Ordinary Cokriging). We used thirty-years-long daily time series and different density of rain gages (from 4 to 70 rain gages). Our study is located in the Ourthe and Ambleve catchment area (2908 km²) in the southern part of Belgium). Spatial interpolation with the geostatistical and Inverse Distance Weighting algorithms outperformed considerably interpolation with the Thiessen polygon. Kriging with an External Drift and Ordinary Cokriging presented the highest Root Mean Square Error between the geostatistical and Inverse Distance Weighting methods. Ordinary Kriging and Inverse Distance Weighting were considered to be the best methods, as they provided smallest Root Mean Square Error for nearly all cases. However, it’s not really the case of extreme estimates for particular return period. The extreme daily rainfall, corresponding to return periods of 25, 50 and 100 years, were computed by fitting of a statistical model to the series of maximum annual precipitation. These estimates were conducted using HYFRAN which allows us to fit 16 different statistical models, in 2 or 3 parameters. The most known are the models of Gumbel, Gamma, Weibull, exponential, Pareto, lognormale, Pearson III and GEV. Our results showed that the behaviour of extreme daily areal rainfall in this area was best described via the Gumbel and lognormal distributions. Using 70 rain gages, little differences in extreme rainfall were observed between the interpolation methods. The estimates from these methods were in the area of 95% confidence intervals of the estimates using the Thiessen polygon. However, when the number of rain gages diminishes, the Universal Kriging and Kriging with External drift methods produced extreme estimates outside the area of 95% confidence intervals of the estimates using the Thiessen polygon with all available stations. The analysis described here provides a means to choose the interpolation method in view to calculate extreme events. It shows to engineers or hydrologists the need for a particular care when working in the regions of sparse data. [less ▲]

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See detailEffects of diffusion in β Cephei stars
Bourge, P*-O; Théado, S.; Thoul, Anne ULg

in Communications in Asteroseismology (2007), 150

We investigate the effects of the radiatively-driven diffusion of Fe, C, N and O in β Cephei stellar models.

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See detailThe effects of divided attention on the occurrence of false memories
Dehon, Hedwige ULg; Brédart, Serge ULg; Siffert, Jason

Poster (2002, April)

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See detailEffects of Dobutamine on Isovolumic and Ejection Phase Indices of Cardiac Contractility in Conscious Healthy Dogs
Mc Entee, Kathleen ULg; Amory, Hélène ULg; Pypendop, B. et al

in Research in Veterinary Science (1998), 64(1, Jan-Feb), 45-50

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was ... [more ▼]

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was recorded together with left ventricular pressure and volume which were measured using a conductance catheter with an integrated microtip pressure sensor. Eight indices of left ventricular systolic performance were derived from these records. Measurements were realised under basal conditions and during an incremental dobutamine challenge. The maximal rate of rise in ventricular pressure (max dP/dt), max dP/dt divided by the developed pressure and the mean systolic ejection rate were the most sensitive indices to detect dobutamine induced changes in contractility with maximal percentage changes of 122+/-11 per cent, 130+/-7 per cent and 102+/-24 per cent respectively. Ejection fraction increased significantly during dobutamine infusion (maximal percentage change of 43+/-9 per cent) whereas the pre-ejection period (PEP) and the left ventricular ejection time (LVET) decreased significantly (maximal percentage change of -41+/-2 per cent and -28+/-3 per cent respectively). All these six indices were significantly correlated with each other. Conversely, the ratio PEP/LVET and the LVET corrected for heart rate dependency showed a maximal percentage change of only -10+/-1 per cent and -16+/-7 per cent, respectively, during the dobutamine infusion and were not significantly correlated with the other contractility indices. This study demonstrated the feasibility of the conductance method to determine cardiac contractility in conscious healthy dogs submitted to a pharmacological stress testing and provides control values for eight indices of left ventricular contractility during dobutamine infusion at increasing dosages. [less ▲]

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See detailEffects of dobutamine on left ventriculoarterial coupling and mechanical efficiency in acutely ischemic pigs
Kolh, Philippe ULg; Lambermont, Bernard ULg; Ghuysen, Alexandre ULg et al

in Journal of Cardiovascular Pharmacology (2005), 45(2), 144-152

This study investigated the effects of dobutamine on left ventriculoarterial (VA) coupling and mechanical efficiency in acutely ischemic pigs. Experiments were performed in 12 pigs in which vascular ... [more ▼]

This study investigated the effects of dobutamine on left ventriculoarterial (VA) coupling and mechanical efficiency in acutely ischemic pigs. Experiments were performed in 12 pigs in which vascular properties, including peripheral resistance (R-2), compliance (C), and arterial elastance (E-a), were estimated with a windkessel model, and left ventricular (LV) function by the slope (E-es) of the end-systolic pressure-volume relationship (ESPVR) and stroke work (SW). VA coupling was defined as E-es/E-a, and mechanical efficiency as SW/pressure-volume area (PVA). In all animals, the left anterior descending coronary artery was ligated after basal measures. The animals were then randomly divided into 2 groups: group CTRL (n = 6) was followed for 180 minutes without other intervention, whereas group DOBU (n = 6) was infused with dobutamine (5 mug(.)kg(-1.)min(-1)) starting after T60 measures. Coronary occlusion induced a rightward shift of ESPVR and a decrease in E-es from 3.67 +/- 0.33 to 1.92 +/- 0.20 mm Hg(.)mL(-1), while E-a changed from 3.33 +/- 0.56 to 4.65 +/- 0.29 mm Hg(.)mL(-1), R-2 from 1.72 +/- 0.30 to 2.38 +/- 0.16 mm Hg(.)s(.)mL(-1), and C from 0.78 +/- 0.16 to 0.46 +/- 0.08 mL(.)mm Hg-1. This altered VA coupling from 1.22 +/- 0.11 to 0.44 +/- 0.07. SW decreased from 4056 +/- 223 to 2372 +/- 122 mm Hg(.)mL, and PVA and SW/PVA decreased from 5575 +/- 514 to 4830 +/- 3.17 mm Hg(.)mL, and from 0.76 +/- 0.04 to 0.49 +/- 0.03, respectively. In group DOBU, dobutamine restored E-es and the position of ESPVR to baseline values, while E-a decreased to 3.39 +/- 0.34 mm Hg(.)mL(-1) because of an R-2 decrease to 1.60 +/- 0.24 mm Hg(.)s(.)mL(-1). VA coupling was restored. SW and PVA increased to 3833 +/- 180 mm Hg(.)mL and to 7498 +/- 442 mm Hg(.)mL, respectively, while SW/PVA was unchanged. In ischemic pigs, dobutamine restored VA coupling through an increase in LV contractility and decrease in arterial elastance as a result of peripheral vasodilatation. However, myocardial oxygen consumption was increased, and mechanical efficiency impaired. [less ▲]

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See detailEffects of dolomite lime and clearcut on nitrate leaching from acid forest soils
Carnol, Monique ULg

Conference (1999, May)

Forest liming has received increased attention since the 1980s, when unusual needle yellowing and fall were observed in large parts of Europe and North America. This ‘new forest decline’ has been ... [more ▼]

Forest liming has received increased attention since the 1980s, when unusual needle yellowing and fall were observed in large parts of Europe and North America. This ‘new forest decline’ has been attributed to several causes acting individually or in synergy, amongst which were 'acid rain', nitrogen saturation and nutritional imbalances. Liming at moderate doses was suggested as a counteracting measure against soil acidification and to remove nutritional deficiencies. Another major forest management operation is whole tree harvesting. Both liming and clearcut may however affect the water quality leaving the treated areas. In particular, nitrate leaching is of major concern, as nitrate leaching may be linked to soil acidification, associated cation and/or aluminium release, and nitrate contamination of surface and groundwater. In this paper, I summarise main results of studies performed in the Belgian Ardennes. In this area, the acid brown soils are naturally poor in magnesium and the observed forest dieback symptoms were supposed to be the consequence of increased pollution exacerbating magnesium deficiency. Liming was suggested for prevention and correction. However, possible side effects, in particular on soil solution and stream water chemistry needed to be evaluated. Another major concern was the effects of clearcut operations on the streamwater quality in this area important for drinking water collection. The effects of dolomite lime were investigated at the watershed, plot and laboratory level. Paired watersheds of approximately 80 ha were mainly covered with Picea abies. One watershed of each pair was limed with 3 T/ha of fine ground dolomite and 200 kg/ha K2SO4. Runoff chemistry was analysed for major cations and anions and time series intervention analysis was used to detect statistically significant changes in stream water chemistry. Results showed increased magnesium concentrations immediately after liming, but a major part of the lime was retained by the soil system, and consequences on water chemistry were minor. However, in the plot study, where 5 T ha-1 of a dolomite lime suspension were applied to adjacent Quercus petraea and Picea abies stands, soil solution nitrate concentrations were significantly increased through liming in the Quercus plots. Increased net nitrification in the Quercus stand was confirmed by potential net nitrification measurements in the laboratory. The effects of tree harvesting on streamwater ion concentrations were investigated by clear felling 22 ha (9650 m3 wood) of a 81 ha watershed. This area represented one third of the forested area, the remaining area being covered equally with young plantations and 70-100 year old Picea abies. First data indicate increased potassium, iron, lead and organic carbon concentrations, but no major change in streamwater nitrate concentrations. Results will be discussed in relation to literature data and known controlling factors of the nitrification process. This analysis reveals that the speed, extent and duration of a perturbation in nitrate leaching after liming or felling vary at different sites. Risks assessment for nitrate leaching is therefore difficult and prediction of nitrate leaching in response to a perturbation remains an important challenge for further studies. In particular, basic controls of the nitrification process and relation nitrification/immobilisation need further investigation. [less ▲]

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See detailEffects of domperidone on QTc interval in infants
Vieira, MC; Miyague, NI; Van Steen, Kristel ULg et al

in Acta Paediatrica (2012), 101(5), 494-496

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See detailEffects of Dopamine Agonists on Appetitive and Consummatory Male Sexual Behavior in Japanese Quail
Castagna, C.; Ball, G. F.; Balthazart, Jacques ULg

in Pharmacology, Biochemistry & Behavior (1997), 58(2), 403-14

The effects of pharmacological manipulations of dopaminergic transmission on appetitive and consummatory aspects of male sexual behavior were investigated in castrated male Japanese quail treated with ... [more ▼]

The effects of pharmacological manipulations of dopaminergic transmission on appetitive and consummatory aspects of male sexual behavior were investigated in castrated male Japanese quail treated with exogenous testosterone. Appetitive male sexual behavior was assessed by measuring a learned social proximity response and consummatory behavior was assessed by measuring copulatory behavior per se. The nonselective dopamine receptor agonist, apomorphine, inhibited in a dose-dependent manner both components of male sexual behavior. Two indirect dopamine agonists were also tested. Nomifensine, a dopamine re-uptake inhibitor, decreased appetitive sexual behavior but increased the frequency of mount attempts, a measure of consummatory sexual behavior. Amfonelic acid, a compound that enhances dopaminergic tone by a complex mechanism, increased aspects of both appetitive and consummatory behaviors. These data suggest that, in quail, as in rodents, increases in dopaminergic tone facilitate both appetitive and consummatory aspects of male sexual behavior. Apomorphine may be inhibitory in quail because it acts primarily on D2-like receptors, unlike in rats, where it stimulates sexual behavior and acts primarily on D1-like receptors at low doses but interacts with D2-like receptors at higher doses. This is supported by the observation that stereotyped pecking, a behavior stimulated selectively in quail by D2 agonists, was increased by apomorphine but not by the two indirect agonists. The observed partial dissociation between the effects of these dopaminergic agonists on appetitive and consummatory sexual behaviors suggests that these two components of male sexual behavior may be controlled by the action of dopamine through different neuronal systems. [less ▲]

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See detailEffects of E. Coli endotoxin on pulmonary resistance in intact dogs
D'Orio, Vincenzo ULg; HALLEUX, J; RODRIGEZ, LM et al

in Critical Care Medicine (1986), 14

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See detailThe Effects of Early Retirement on Youth Unemployment: The Case of Belgium
Jousten, Alain ULg

Conference (2008)

The paper studies the effect of the pension system on the unemployment of the young

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See detailThe effects of early retirement on youth unemployment: the case of Belgium
Jousten, Alain ULg; Lefebvre, Mathieu ULg; Pestieau, Pierre ULg et al

in Gruber, Jonathan; Wise, David (Eds.) Social Security Programs and Retirement around the World: The Relationship to Youth Employment (2010)

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See detailEffects of eccentric versus concentric training on mouse muscle phenotype
Hody, Stéphanie ULg; Lacrosse, Zoé ULg; Leprince, Pierre ULg et al

in Abstract Book of 10th Meeting of Belgian Society for Neuroscience (2013, May)

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