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See detailCytochemical labelling of chitin
Compère, Philippe ULiege

in Giraud-Guille, Maie-Madeleine (Ed.) Chitin in Life Sciences (1997)

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See detailCytochemistry of the tergite epicuticle of Glomeris marginata (Villers) (MYRIAPODA, DIPLOPODA): preliminary experimental results
Compère, Philippe ULiege; Defise, Stéphane; Goffinet, Gerhard ULiege

in Mémoires du Muséum d'Histoire naturelle (Paris) - Acta Myriapodologica (1996), 169

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See detailCytochrome P450 1A1 expression in cetacean skin biopsies from the Indian Ocean
Jauniaux, Thierry ULiege; Farnir, Frédéric ULiege; Fontaine, Michael et al

in Marine Pollution Bulletin (2011)

Detailed reference viewed: 54 (19 ULiège)
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See detailCytochrome P450-mediated cardiovascular drug interactions.
SCHEEN, André ULiege

in Expert opinion on drug metabolism & toxicology (2011), 7(9), 1065-82

Introduction: There are numerous drug-drug interactions (DDIs) related to cardiovascular medications and many of these are mediated via the cytochrome P450 (CYP) system. Some of these may lead to serious ... [more ▼]

Introduction: There are numerous drug-drug interactions (DDIs) related to cardiovascular medications and many of these are mediated via the cytochrome P450 (CYP) system. Some of these may lead to serious adverse events and it is, therefore, essential that clinicians are aware of the important interactions that occur. Areas covered: An extensive literature search was performed to analyze the CYP-mediated cardiovascular DDIs that lead to a loss of efficacy or potential toxicity. Cardiovascular drugs may be victims or act as perpetrators of DDIs. The paper analyzes CYP-mediated drug interactions concerning anticoagulants, antiplatelet agents, antiarrhythmics, beta-blockers, calcium antagonists, antihypertensive medications, lipid-lowering drugs and oral antidiabetic agents. Expert opinion: Cardiovascular DDIs involving the CYP system are numerous. Additionally, the spectrum of drugs prescribed is constantly changing, particularly with cardiovascular diseases and it is not necessarily the case that drugs that had shown safety earlier will always show safety. Clinicians are encouraged to develop their knowledge of CYP-mediated DDIs so that they can choose safe drug combination regimens, adjust drug dosages appropriately and conduct therapeutic drug monitoring for drugs with narrow therapeutic indices. [less ▲]

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See detailCYTODUCTION IN CHLAMYDOMONAS-REINHARDTII
Matagne, René-Fernand ULiege; Remacle, Claire ULiege; DINANT, M.

in Proceedings of the National Academy of Sciences of the United States of America (1991), 88(16), 7447-7450

After conjugation between Chlamydomonas gametes of opposite mating type, a transient dikaryon is formed. The two nuclei fuse within 4-6 hr after mating. The young diploid zygote differentiates into ... [more ▼]

After conjugation between Chlamydomonas gametes of opposite mating type, a transient dikaryon is formed. The two nuclei fuse within 4-6 hr after mating. The young diploid zygote differentiates into dormant zygospore competent to complete meiosis, or more rarely (2-10% of cases) it undergoes mitosis to produce a stable diploid progeny. We here bring genetical, biochemical, and cytological evidence that among the mitotic zygotes, a large proportion of them undergo cytokinesis without fusion of the nuclei - a process that has been termed "cytoduction." By using appropriate genetic markers, haploid cytoductants that possess the nuclear genotype of one parent and the chloroplast marker of the other parent can easily be isolated. Genetical analysis and hybridization experiments moreover show that many haploid cytoductants transmit the chloroplast DNA molecules of both parents and that, as in diploids, these DNA copies occasionally recombine. This process of cytoduction extends the life cycle of Chlamydomonas and provides new tools for its genetic analysis. [less ▲]

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See detailCytofluorometric analysis of prostate cancer specimens: Histological and clinical correlations
de Leval, Laurence ULiege; Waltregny, David ULiege; Greimers, Roland ULiege et al

in Acta Urologica Belgica (1994, January), 62

DNA histograms were oblained by flow cytometry for 39 human prostate carcinomas (27 total proslatectomy specimens, 5 biopsies and 7 transuretral resections). The study was performed on formalin-fixed and ... [more ▼]

DNA histograms were oblained by flow cytometry for 39 human prostate carcinomas (27 total proslatectomy specimens, 5 biopsies and 7 transuretral resections). The study was performed on formalin-fixed and paraffin-embedded. material. In this report, ploidy index did not seem to be a good marker of prognosis as no significant variation in ploidy was found neither among the different stages nor among the different Gleason categories. Proliferative index of the tumors seemed to be a more sensitive parameter; a significant relation was observed between proliferative index and stage of the tumor. The authors discuss these results under the light of previously reported observations. [less ▲]

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See detailCytogenetic Changes in Hepatocarcinomas from Rats Treated with Chronic Exposure to Diethylnitrosamine
Herens, Christian ULiege; Alvarez Gonzalez, Maria-Luz ULiege; Barbason, Hervé ULiege

in Cancer Genetics & Cytogenetics (1992), 60(1), 45-52

Cytogenetic analysis of rat hepatocarcinomas obtained after diethylnitrosamine (DEN) exposure showed a wide variety of numerical and structural chromosomal changes: 53 of 86 hepatocellular carcinomas ... [more ▼]

Cytogenetic analysis of rat hepatocarcinomas obtained after diethylnitrosamine (DEN) exposure showed a wide variety of numerical and structural chromosomal changes: 53 of 86 hepatocellular carcinomas showed at least one recurrent chromosomal aberration. Some of these recurrent changes occurred in several tumors. Chromosomes 1, 3, 11, and 12 were abnormal in more than 30% of the carcinomas; chromosomes 2, 4, 5, and 10 were abnormal in 10%. Moreover, chromosomes 1 and 10 were generally lost or deleted and chromosome 3, 4, and 11 were very often gained. The most frequent anomaly was loss of chromosome 1 which was observed in 35% of the tetraploid cell populations. The occurrence in several tumors of recurrent chromosomal rearrangements as well as various repeated aneuploidies strongly suggests that these anomalies are implicated in the process of rat hepatocarcinogenesis induced by DEN treatment. [less ▲]

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See detailCytogenetic Evaluation of the Stallion
Durkin, Keith ULiege; Raudsepp, Terje; Chowdhary, Bhanu P

in McKinnon, Angus O; Squires, Edward L; Vaala, Wendy E (Eds.) et al Equine Reproduction (2011)

A normal chromosome complement is essential for normal fertility. Chromosome aberrations – numerical or structural – may lead to a range of deformities and defects that can be physical and/or ... [more ▼]

A normal chromosome complement is essential for normal fertility. Chromosome aberrations – numerical or structural – may lead to a range of deformities and defects that can be physical and/or physiological. Irrespectively, aberrations result in complete loss of fertility or reduced fertility in stallions. They lead to the production of abnormal gametes that contribute to early embryonic deaths. Moreover, viable offspring from such gametes may carry the same chromosomal abnormality and have similar fertility problems. Economic losses incurred due to reduced stallion fertility or infertility is huge. Cytogenetic analysis is a simple and straightforward approach to ensure that the animals have a normal chromosome complement. To protect the economic interests of horse owners, breeders, prospective buyers, insurance companies, etc., the equine industry is strongly encouraged to mandate cytogenetic analysis of all breeding animals at an early age. The relatively inexpensive practice will also prevent the spread of chromosome aberrations as is expected from the progenies of the A P Valentine – a fairly successfully horse on the race track – and similar other carriers of abnormalities. [less ▲]

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See detailCytogenetic Studies of Rwandan Pediatric Patients Presenting with Global Developmental Delay, Intellectual Disability and/or Multiple Congenital Anomalies.
Uwineza, Annette; Hitayezu, Janvier; JAMAR, Mauricette ULiege et al

in Journal of tropical pediatrics (2016)

Global developmental delay (GDD) is defined as a significant delay in two or more developmental domains: gross or fine motor, speech/language, cognitive, social/personal and activities of daily living ... [more ▼]

Global developmental delay (GDD) is defined as a significant delay in two or more developmental domains: gross or fine motor, speech/language, cognitive, social/personal and activities of daily living. Many of these children will go on to be diagnosed with intellectual disability (ID), which is most commonly defined as having an IQ <75 in addition to impairment in adaptive functioning. Cytogenetic studies have been performed in 664 Rwandan pediatric patients presenting GDD/ID and/or multiple congenital abnormalities (MCA). Karyotype analysis was performed in all patients and revealed 260 chromosomal abnormalities. The most frequent chromosomal abnormality was Down syndrome and then Edward syndrome and Patau syndrome. Other identified chromosomal abnormalities included 47,XX,+del(9)(q11), 46,XY,del(13)(q34) and 46,XX,der(22)t(10;22)(p10;p10)mat. In conclusion, our results highlight the high frequency of cytogenetically detectable abnormalities in this series, with implications for the burden on the healthcare. This study demonstrates the importance of cytogenetic analysis in patients with GDD/ID and MCA. [less ▲]

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See detailCytogenetic study of bovine oocytes matured in vitro
Ectors, Fabien ULiege; Koulischer, Lucien ULiege; Jamar, M. et al

in Theriogenology (1995), 44(3), 445-450

Described in the present paper is a cytogenetic study of bovine oocytes matured in vitro. The cumulus-oocyte complexes (COC), punctured from ovaries recovered in a local slaughterhouse, were classified ... [more ▼]

Described in the present paper is a cytogenetic study of bovine oocytes matured in vitro. The cumulus-oocyte complexes (COC), punctured from ovaries recovered in a local slaughterhouse, were classified into 3 groups according to follicular diameter 1 to 4mm, 5 to 8mm and 9 to 13 mm. Metaphases available for observation were classified as metaphase I, haploid and diploid metaphase II. High levels of haploid metaphases II (90.6, 86.9 and 94.4 %) among the 3 groups of follicular sizes indicated successful meiotic resumption during in vitro maturation and suggested that cytoplasmic maturation may be responsible for low developmental rate after IVM, IVF and in vitro development (IVD). [less ▲]

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See detailCytogenetics of a new trispecies hybrid In cotton: [(Gossypium Hirsutum L. X G-Thurberi Tod.)(2) X G-Longicalyx Hutch. & Lee]
Konan, On.; D'Hont, A.; Baudoin, Jean-Pierre ULiege et al

in Plant Breeding (2007), 126(2), 176-181

Detailed reference viewed: 45 (6 ULiège)
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See detailCytogenomic analyses for fertility and sex determination defects in the horse.
Durkin, Keith ULiege; Raudsepp, T; Chowdhary, B.P.

in Proceedings of the 33rd Annual Meeting of the Texas Genetics Society (2006, April)

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See detailCytokine and anti-cytokine strategies in inflammatory reaction modulation
Delannoy, I.; Lekeux, Pierre ULiege; Miossec, P.

in Veterinary Research (1993), 24

Evidence of the importance of a cytokine cascade in the induction and control of the inflammatory reaction is increasing. Although cytokines are required in the inflammatory process in response to ... [more ▼]

Evidence of the importance of a cytokine cascade in the induction and control of the inflammatory reaction is increasing. Although cytokines are required in the inflammatory process in response to infection or injury, their overproduction, particularly that of interleukin-1 (IL-1) and tumor necrosis factor (TNF), can lead to local/systemic pathology. Selective inhibition of the synthesis or of the action of specific cytokines may be of therapeutic benefit. Various strategies for blocking IL-1 and TNF activities have been presented. While selective inhibition of cytokine synthesis is still in the early experimental phase, specific blockade of soluble cytokine action following synthesis and release from cells is undergoing preliminary clinical trials in humans. Animal data suggest that antimonoclonal therapy such as monoclonal antibodies to TNF, IL-1 receptor antagonists or soluble receptors to TNF and IL-1 can be effective in the modulation of the inflammatory reaction. Modulation of the cytokine network in some diseases might also include the use of anti-inflammatory cytokines. Nonetheless, the possibilities of side effects due to impaired host-defense mechanisms with the IL-1 or TNF blockade must also be taken into consideration. [less ▲]

Detailed reference viewed: 43 (0 ULiège)
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See detailCytokine and chemokine expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinosinusitis.
Peeters, Dominique ULiege; Peters, I. R.; Helps, C. et al

in Proceedings of the 16th Annual Congress of the ECVIM-CA (2006)

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See detailCytokine and transcription factor expression by Aspergillus fumigatus-stimulated peripheral blood mononuclear cells in dogs with sino-nasal aspergillosis
Vanherberghen, Morgane; Bureau, Fabrice ULiege; Peters, I.R. et al

in Veterinary Immunology and Immunopathology (2013), 154(3-4), 111-20

Detailed reference viewed: 28 (9 ULiège)