Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailDevelopment of a Standard Reference Material for Metabolomics Research
Phinney, K; Ballihaut, G; Bedner, M et al

in Analytical Chemistry (2013), 85(24), 11732-11738

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support technology ... [more ▼]

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support technology development in metabolomics research. SRM 1950 Metabolites in Human Plasma is intended to have metabolite concentrations that are representative of those found in adult human plasma. The plasma used in the preparation of SRM 1950 was collected from both male and female donors, and donor ethnicity targets were selected based upon the ethnic makeup of the U.S. population. Metabolomics research is diverse in terms of both instrumentation and scientific goals. This SRM was designed to apply broadly to the field, not towards specific applications. Therefore, concentrations of approximately 100 analytes, including amino acids, fatty acids, trace elements, vitamins, hormones, selenoproteins, clinical markers, and perfluorinated compounds (PFCs), were determined. Value assignment measurements were performed by NIST and the Centers for Disease Control and Prevention (CDC). SRM 1950 is the first reference material developed specifically for metabolomics research. [less ▲]

Detailed reference viewed: 34 (2 ULg)
Full Text
See detailDevelopment of a statistical reduction method for the Palomar Fiber Nuller
Hanot, Charles ULg; Mennesson, Bertrand; Serabyn, Eugene et al

in Danchi, W. C.; Delplancke, F.; Rajagopal, J. K. (Eds.) Optical and Infrared Interferometry II (2010, July)

A unique statistical data analysis method has been developed for reducing nulling interferometry data. The idea is to make use of the statistical distributions of the fluctuating null depths and beam ... [more ▼]

A unique statistical data analysis method has been developed for reducing nulling interferometry data. The idea is to make use of the statistical distributions of the fluctuating null depths and beam intensities to retrieve the astrophysical null depth in the presence of fluctuations. The approach yields an accuracy much better than is possible with standard data reduction methods, because the accuracy of the null depth is not limited by the sizes of the phase and intensity errors but by the uncertainties on their statistical distributions. The result is an improvement in the instrumental null depth measurement limit of roughly an order of magnitude. We show in this paper that broadband null depths of 10[SUP]-4[/SUP] can be measured in the lab with our infrared Fiber Nuller without achromatic phase shifters. On sky results are also dramatically improved, with measured contrasts up to a couple of 10[SUP]-4[/SUP] with our instrument mounted on the Hale telescope at the Palomar Observatory. This statistical analysis is not specific to our instrument and may be applicable to other interferometers. [less ▲]

Detailed reference viewed: 29 (2 ULg)
See detailDevelopment of a strategy to study toxicodynamic of pollutants in spawning sea turtles
Dyc, Christelle ULg; Bouquegneau, Jean-Marie ULg; De Pauw-Gillet, Marie-Claire ULg et al

in Proceedings of the 29th Annual Symposium on Sea Turtle Biology and Conservation (2009)

Detailed reference viewed: 15 (2 ULg)
See detailDevelopment of a strategy to study toxicodynamic of pollutants in spawning sea turtles from French West Indies (Guadeloupe and Martinique)
Dyc, Christelle ULg; Debier, Cathy; Thomé, Jean-Pierre ULg et al

Conference (2008, November)

Sea turtles including the green turtle Chelonia mydas and the hawksbill turtle Eretmochelys imbricata are critically endangered species, facing different factors as marine pollution. There is a blatant ... [more ▼]

Sea turtles including the green turtle Chelonia mydas and the hawksbill turtle Eretmochelys imbricata are critically endangered species, facing different factors as marine pollution. There is a blatant lack of data dealing with toxicants such as metals and persistent organic pollutants (POPs) in sea turtles. We developed a strategy to apprehend levels, effects and transfer to offspring of several pollutants in sea turtles. Sampling of blood, subcutaneous tissue and eggs of 15 gravid C. mydas and E. imbricata was carried out between July and September 2008 in Martinique (Diamant’s beach) and Guadeloupe (Petite Terre and Marie-Galante). Blood was collected from the dorso-cervical sinus and subcutaneous tissue was sampled in shoulder of the spawning females using a 5 mm biopsy punch (Kai Europe GmbH, Germany). Total blood and serum were successfully taken for metal, POP and biomarker investigations. T-mercury was analyzed by DMA milestones while PCBs, DDT and chlordecone were analyzed by EDC Ni63 high performance gas chromatography HPLC. Samples of serum were analyzed for vitamins (A and E) by HPLC and for thyroid hormones (triiodothyronine and thyroxine) by radioimmunoassay. In parallel to this field study, a cell model using 3T3-L1 cell line was built up to test in vitro effects of PCBs and mercury as well as the relationship between in vitro exposure and fat mobilization. Preliminary results showed a dose-response relationship between increased Aroclor 1234 and 1252 concentrations (0.5 ppb, 1 ppb and 1.5 ppb) and adipocyte mortality (Nucleocounter). The strategy we propose here will bring further insights on levels and potential impact of pollutants on female sea turtles and their offspring. [less ▲]

Detailed reference viewed: 58 (9 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a strategy to study toxicodynamic of pollutants in spawning sea turtles from the French West Indies
Dyc, Christelle ULg; Bouquegneau, Jean-Marie ULg; De Pauw-Gillet, Marie-Claire ULg et al

Poster (2008, October)

Sea turtles including the green turtle Chelonia mydas and the hawksbill turtle Eretmochelys imbricata are critically endangered species, facing different factors as marine pollution. There is a blatant ... [more ▼]

Sea turtles including the green turtle Chelonia mydas and the hawksbill turtle Eretmochelys imbricata are critically endangered species, facing different factors as marine pollution. There is a blatant lack of data dealing with toxicants such as metals and persistent organic pollutants (POPs) in sea turtles. We developed a strategy to apprehend levels, effects and transfer to offspring of several pollutants in sea turtles. Sampling of blood, subcutaneous tissue and eggs of 15 gravid C. mydas and E. imbricata was carried out between July and September 2008 in Martinique (Diamant’s beach) and Guadeloupe (Petite Terre and Marie-Galante). Blood was collected from the dorso-cervical sinus and subcutaneous tissue was sampled in shoulder of the spawning females using a 5 mm biopsy punch (Kai Europe GmbH, Germany). Total blood and serum were successfully taken for metal, POP and biomarker investigations. T-mercury was analyzed by DMA milestones while PCBs, DDT and chlordecone were analyzed by EDC Ni63 high performance gas chromatography HPLC. Samples of serum were analyzed for vitamins (A and E) by HPLC and for thyroid hormones (triiodothyronine and thyroxine) by radioimmunoassay. In parallel to this field study, a cell model using 3T3-L1 cell line was built up to test in vitro effects of PCBs and mercury as well as the relationship between in vitro exposure and fat mobilization. Preliminary results showed a dose-response relationship between increased Aroclor 1234 and 1252 concentrations (0.5 ppb, 1 ppb and 1.5 ppb) and adipocyte mortality (Nucleocounter). The strategy we propose here will bring further insights on levels and potential impact of pollutants on female sea turtles and their offspring. [less ▲]

Detailed reference viewed: 74 (11 ULg)
See detailDevelopment of a Substitute Mixture for Diesel Fuel
Reiter, A M; Wallek, T; Mair-Zelenka, P et al

Conference (2012)

Full Text
See detailDevelopment of a subwavelength grating vortex coronagraph of topological charge 4 (SGVC4)
Delacroix, Christian ULg; Absil, Olivier ULg; Carlomagno, Brunella ULg et al

in Ramsay, Suzanne; McLean, Ian; Takami, Hideki (Eds.) Ground-based and Airborne Instrumentation for Astronomy V (2014, July 08)

One possible solution to achieve high contrast direct imaging at a small inner working angle (IWA) is to use a vector vortex coronagraph (VVC), which provides a continuous helical phase ramp in the focal ... [more ▼]

One possible solution to achieve high contrast direct imaging at a small inner working angle (IWA) is to use a vector vortex coronagraph (VVC), which provides a continuous helical phase ramp in the focal plane of the telescope with a phase singularity in its center. Such an optical vortex is characterized by its topological charge, i.e., the number of times the phase accumulates 2pi radians along a closed path surrounding the singularity. Over the past few years, we have been developing a charge-2 VVC induced by rotationally symmetric subwavelength gratings (SGVC2), also known as the Annular Groove Phase Mask (AGPM). Since 2013, several SGVC2s (or AGPMs) were manufactured using synthetic diamond substrate, then validated on dedicated optical benches, and installed on 10-m class telescopes. Increasing the topological charge seems however mandatory for cancelling the light of bright stars which will be partially resolved by future Extremely Large Telescopes in the near-infrared. In this paper, we first detail our motivations for developing an SGVC4 (charge 4) dedicated to the near-infrared domain. The challenge lies in the design of the pattern which is unrealistic in the theoretically perfect case, due to state-of-the-art manufacturing limitations. Hence, we propose a new realistic design of SGVC4 with minimized discontinuities and optimized phase ramp, showing conclusive improvements over previous works in this field. A preliminary validation of our concept is given based on RCWA simulations, while full 3D finite-difference time-domain simulations (and eventually laboratory tests) will be required for a final validation. [less ▲]

Detailed reference viewed: 23 (5 ULg)
Peer Reviewed
See detailDevelopment of a sustained release bolus for lambs
Evrard, Brigitte ULg; Dechesne, Jean-Paul; Fagetton, Xavier et al

Conference (1990, March)

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailDevelopment of a sustained release bolus for sheep : "in vitro" and "in vivo" results
Evrard, Brigitte ULg; Dechesne, Jean-Paul; Fagetton, Xavier et al

in Proceedings of 19th International Symposium on controlled release of Bioactive Materials (1992)

Detailed reference viewed: 5 (2 ULg)
See detailDevelopment of a technique to measure 17β-estradiol in discrete brain regions in zebra finch
Charlier, Thierry ULg; Po, Kelvin WL; Shah, Amit H et al

Poster (2008)

Detailed reference viewed: 10 (1 ULg)
See detailDevelopment of a test battery for assessing cognitive functions of elderly patients with Down syndrome
Georges, Michel ULg; Thewis, B.; Van der Linden, Martial ULg et al

in Revue de Neuropsychologie (2001), 11(4), 549-579

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess ... [more ▼]

Post-mortem studies of Down syndrome (DS) individuals older than 35 years show that almost 100% of them develop the neuropathological symptoms of Alzheimer disease (AD). A test battery designed to assess several domains of cognition was administered to a group of 12 DS individuals older than 35 years. It proved sensitive to individual differences and thus appears to be appropriate for the observation of cognitive change linked to age. Statistical analyses do not reveal cognitive changes in the DS subjects after one year time. However qualitative analyses of individual profiles suggest a cognitive decline in one subject. Additionally, in a PET-scan examination, three subjects present a mild decrease in cerebral glucose metabolism similar to that usually observed in AD. An AD diagnostic though remains uncertain at this stage. [less ▲]

Detailed reference viewed: 134 (9 ULg)
Full Text
Peer Reviewed
See detailDevelopment of a test to assess the Banana Bunchy Top Virus transmissibility through direct analysis of its aphid vector Pentalonia nigronervosa
De Clerck, Caroline ULg; Francis, Frédéric ULg; Lepoivre, Philippe ULg et al

in Communications in Agricultural and Applied Biological Sciences (2013), 78(1), 49-54

Detailed reference viewed: 93 (27 ULg)
See detailDevelopment of a thorax CT-scan based finite element model for thoracic injury assessment
Nsiampa, Nestor; D'Otreppe, Vinciane ULg; Robbe, Cyril ULg et al

Conference (2011, November 14)

Detailed reference viewed: 48 (7 ULg)
Peer Reviewed
See detailDevelopment of a translation stage for in situ non-invasive analysis and high resolution imaging
Strivay, David ULg; Clar, Mathieu ULg; Rakkaa, Saïd ULg et al

Poster (2016, March)

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems ... [more ▼]

Non-invasive imaging techniques and analytical instrumentation for cultural heritage object studies have undergone a tremendous development over the last years. Many new miniature and/or handheld systems have been developed and optimized. Nonetheless, these instruments are usually used with a tripod or a manual position system. This is very time consuming when performing point analysis or 2D scanning of a surface. The Centre Européen d’Archéométrie (CEA) has build a translation system made of pluggable rails of 1 m long with a maximum length and height of 3 m. Three motors embedded in the system allow the platform to be moved along these axis, toward and backward from the sample. The rails hold a displacement system, providing a continuous movement. Any position can be reached with a reproducibility of 0.1 mm. The displacements are controlled by an Ethernet connection through a laptop computer running a multiplatform homemade software written in JAVA. This software allows a complete control over the positioning using a simple, unique, and concise interface. Automatic scanning can be performed over a large surface of 3 meters on 3 meters. The Ethernet wires provide also the power for the different motors and, if necessary the detection head. The platform has been originally designed for a XRF detection head (with its full power alimentation) but now can accommodate many different systems like IR reflectography, digital camera, hyperspectral camera, Raman probes, etc. The positioning system can be modified to combine the acquisition software of the imaging or analytical techniques and the positioning software. [less ▲]

Detailed reference viewed: 37 (5 ULg)