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See detailEffect of pressure, temperature, fluorine doping, and rare earth elements on the phonon density of states of LFeAsO studied by nuclear inelastic scattering
Sergueev, I.; Hermann, Raphael ULg; Bessas, D. et al

in PHYSICAL REVIEW B (2013), 87(6), 064302-9

We have performed systematic studies of the lattice dynamics in LFeAsO (L = La, Ce, Pr, Nd, Sm) in the parent and in the similar to 10% F-doped compounds as a function of pressure and temperature. We have ... [more ▼]

We have performed systematic studies of the lattice dynamics in LFeAsO (L = La, Ce, Pr, Nd, Sm) in the parent and in the similar to 10% F-doped compounds as a function of pressure and temperature. We have found that the modifications in the partial Fe density of phonon states are mainly governed by the Fe-As bond length. The change of this bond length explains the change of the Fe density of phonon states above 25 meV. We further observe anomalies in the behavior of the phonon mode near 16 meV. In the parent phase, this mode softens anomalously upon cooling through the structural phase transition. Upon F doping, this mode hardens indicating a strong electron-phonon coupling. This suggests that the corresponding phonons play an important role in the competition between superconductivity and magnetism in these materials. DOI: 10.1103/PhysRevB.87.064302 [less ▲]

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See detailEffect of preventive antioxidant supplementation on lung function, airway inflammation and pulmonary 8-epi-PGF2 of calves exposed to ozone
Kirschvink, Nathalie; Fievez, Laurence ULg; Jacqmot, O. et al

in Proceedings: Réunion de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques (2001)

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See detailEffect of previous antidepressant therapy on the growth hormone response to apomorphine.
Pitchot, William ULg; Hansenne, Michel ULg; Gonzalez Moreno, A. et al

in Neuropsychobiology (1995), 32(1), 19-22

Several lines of evidence suggest a role for dopamine in the pathophysiology of depression. In 1988, we reported a blunted response of growth hormone (GH) to apomorphine, a dopaminergic agonist, in ... [more ▼]

Several lines of evidence suggest a role for dopamine in the pathophysiology of depression. In 1988, we reported a blunted response of growth hormone (GH) to apomorphine, a dopaminergic agonist, in endogenous depression. However, an antidepressant washout period is a major confounding factor in studies assessing the GH response to apomorphine. Indeed, whereas the influence of tricyclic antidepressants on the GH response to apomorphine is presently unknown, several reports have suggested that tricyclics may impair the GH response to clonidine for periods longer than 3 weeks following their discontinuation. In the present study, we hypothesized that a blunted GH response to apomorphine in depressed patients could be related to the recent administration of antidepressants. Therefore, the GH response to apomorphine (0.5 mg) was studied in 11 male DSM-III-R major depressive inpatients who had never received antidepressant therapy (group 1) compared to 11 normal controls and 11 major depressive inpatients drug free for at least 2 weeks (group 2). The three groups differed significantly in the GH peak response to apomorphine: mean (SD) 5.4 (4.0) ng/ml in group 1, 25.5 (10.7) in normal controls, and 5.5 (5.1) in group 2 (F = 15.5, df = 3, 30, p = 0.00001). While group 1 and normal controls (F = 21.8, p = 0.0002) as well as group 2 and controls (F = 5.6, p = 0.03) differed significantly, group 1 and group 2 did not (F = 0.18, p = 0.68). These results suggest that a washout period of 2 weeks could be sufficient in studies assessing the GH response to apomorphine. [less ▲]

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See detailEffect of processing conditions on phenolic compounds and antioxidant properties of date syrup
Abbès, F.; Kchaou, W.; Blecker, Christophe ULg et al

in Industrial Crops & Products (2013), 44

Commercial hydrolytic enzymes (pectinase and cellulase) were investigated for their influence on phenolics and antioxidant activities of date syrup. Content of total phenolics, flavonoids and carotenoids ... [more ▼]

Commercial hydrolytic enzymes (pectinase and cellulase) were investigated for their influence on phenolics and antioxidant activities of date syrup. Content of total phenolics, flavonoids and carotenoids contents were determined spectrophotometrically. Polyphenols composition was examined using HPLC. Seven phenolic compounds (catechin, vanillic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid and sinapic acid) were detected in all date syrup extracts. p-Coumaric acid was the major compound of all date syrup extracts, representing 49.223-63.397%. The antioxidant activity of date syrup was evaluated by various antioxidant assays, including total antioxidant, DPPH scavenging test, FRAP, hydrogen peroxide scavenging activity and metal chelating activity.Results showed that the date syrup prepared after extraction with pectinase and cellulase mixture gave the lowest phenolic and flavonoid contents. For same variety, date syrup prepared after extraction with pectinase and cellulase mixture gave the highest carotenoids amounts. The antioxidant activity, determined by several methods, was significantly affected by the extraction method as well as date varieties. In fact, the date syrup prepared after extraction with pectinase and cellulase mixture gave the lowest antioxidant activity. A good correlation between the antioxidant activity and total phenolic content and flavonoid was observed. The discovery of our research is very important to scientists as well as to the fruit-processing industry to produce juice and syrup with high antioxidant activity. © 2012 Elsevier B.V. [less ▲]

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See detailThe effect of processing on inflammatory markers in induced sputum.
Louis, Renaud ULg; Shute, J.; Goldring, K. et al

in European Respiratory Journal (1999), 13(3), 660-7

The effects of the mucolytic agent, dithioerythritol (DTE), and the temperature at which sputum processing is conducted on cellular and biochemical markers in induced sputum was assessed. Samples from ... [more ▼]

The effects of the mucolytic agent, dithioerythritol (DTE), and the temperature at which sputum processing is conducted on cellular and biochemical markers in induced sputum was assessed. Samples from healthy and atopic asthmatic subjects were treated with either DTE or phosphate-buffered saline (PBS) at 22 or 37 degrees C and compared for cell counts and concentrations of histamine, tryptase, eosinophil cationic protein (ECP), free interleukin (IL)-8, immunoglobulin (Ig)A, IL-8/IgA complexes and secretory component (SC). In addition, the influence of DTE on in vitro mediator release from blood eosinophils, basophils and bronchoalveolar lavage (BAL) mast cells was studied. Processing with DTE improved cytospin quality and increased the cell yield and measurable ECP, tryptase, IgA and SC, but reduced levels of histamine in PBS-treated samples and had no effect on IL-8. Cell counts or mediator levels were similar when sputum was processed at 22 or 37 degrees C, even though DTE induced blood basophils and BAL mast cells to release histamine at 37 degrees C. In spiking experiments, recovery of added ECP, tryptase, total IL-8 and histamine from sputum was similar in DTE- and PBS-processed sputum, but reduced for free IL-8 in PBS-treated samples. In conclusion, dithioerythritol improves cell and mediator recovery without causing cell activation when sputum processing is conducted at room temperature. The extent of recovery depends on the mediator studied. [less ▲]

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See detailEffect of prolactin on alpha and beta chloride cells in the gill epithelium of the saltwater adapted tilapia " Oreochromis niloticus"
Pisam, B.; Auperin, B.; Prunet, P. et al

in Anatomical Record (1993), 235

Tilapia (Oreochromis niloticus), 21 g average body weight, were divided into two groups. A group was maintained in fresh water, whereas another group was adapted for 2 weeks to 20% salt water. Among the ... [more ▼]

Tilapia (Oreochromis niloticus), 21 g average body weight, were divided into two groups. A group was maintained in fresh water, whereas another group was adapted for 2 weeks to 20% salt water. Among the latter, fishes were injected every 2 days for a week with tilapia prolactin (ti-PRL I). Gills were prepared for electron microscopy in order to determine the types and surface areas of chloride cells in each experimental condition. Two types of chloride cells, the alpha and beta cells were easily distinguished on the basis of their location and ultrastructural features in the gills of freshwater fishes, while only one type of cell, the saltwater alpha cells presumably derived from the transformation of the freshwater alpha cells, were encountered in saltwater adapted animals. After PRL injection of saltwater adapted fishes, small chloride cells, which displayed ultrastructural features similar to those of beta cells in freshwater tilapia, reappeared in interlamellar regions of the gills. In the same experimental conditions, the voluminous saltwater alpha cells showed a tendency to resume ultrastructural features more characteristic of the freshwater alpha cells from which they were derived. These observations tend to indicate that prolactin behaves as a "freshwater adapting hormone" and that beta cells are specifically involved in fish adaptation to freshwater living conditions. [less ▲]

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See detailEffect of prolonged exercise on neutrophil myeloperoxidase secretion
Bury, Thierry ULg; PIRNAY, Freddy ULg

in International Journal of Sports Medicine (1995)

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See detailEffect of propofol and sevoflurane on coughing in smokers and non-smokers awakening from general anaesthesia at the end of a cervical spine surgery.
Hans, Pol ULg; Marechal, Hugues ULg; Bonhomme, Vincent ULg

in British Journal of Anaesthesia (2008), 101(5), 731-7

BACKGROUND: Coughing during emergence from general anaesthesia may be detrimental, particularly after cervical spine surgery. We compared the effect of propofol or sevoflurane anaesthesia on the incidence ... [more ▼]

BACKGROUND: Coughing during emergence from general anaesthesia may be detrimental, particularly after cervical spine surgery. We compared the effect of propofol or sevoflurane anaesthesia on the incidence and severity of coughing during recovery in patients undergoing cervical spine surgery via an anterior approach. As a secondary aim, we also evaluated the influences of smoking and estimated residual anaesthetic agent concentrations on coughing. METHODS: Thirty-four patients were enrolled in a randomized prospective, double-blind study to receive either propofol (PPF) or sevoflurane (SEVO) for maintenance of anaesthesia. The decision to perform tracheal extubation was based on specified criteria, including resumption of spontaneous respiration and consciousness. During emergence from anaesthesia and extubation, coughing was observed and graded at predefined times. RESULTS: The incidence of severe coughing was higher in the SEVO group than in the PPF group (59% and 6%, respectively), and also in smokers than in non-smokers (50% and 17%, respectively). The peak incidence of coughing was at tracheal extubation. The probability of coughing was influenced by the estimated residual concentration of anaesthetic agents at extubation, except for smokers in the SEVO group who were at the highest risk of coughing. CONCLUSIONS: The incidence of coughing after cervical spine surgery when tracheal extubation is performed according to clinical criteria is lower after propofol anaesthesia compared with sevoflurane anaesthesia. Smokers are at increased risk of coughing, independently of the type of anaesthesia maintenance. Higher residual concentrations of anaesthetic agents decrease the probability of coughing, except for smokers anaesthetized with sevoflurane. [less ▲]

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See detailEffect of Propofol on in Vitro Lipid Peroxidation Induced by Different Free Radical Generating Systems: A Comparison with Vitamin E
Hans, Pol ULg; Deby, Christiane ULg; Deby-Dupont, G. et al

in Journal of Neurosurgical Anesthesiology (1996), 8(2), 154-8

Propofol has been reported to have antioxidant properties and to inhibit lipid peroxidation. In this study, we examined the ability of propofol to inhibit lipid peroxidation induced by three free radical ... [more ▼]

Propofol has been reported to have antioxidant properties and to inhibit lipid peroxidation. In this study, we examined the ability of propofol to inhibit lipid peroxidation induced by three free radical systems (hydroxyl, ferryl, and oxo-ferryl radicals), and we compared the effect of propofol with that of vitamin E, an endogenous antioxidant. Lipid peroxidation was induced by exposing a linoleic acid emulsion to either water gamma radiation, a ferrous iron-ascorbate solution, or human hemoglobin, generating the hydroxyl, ferryl, and oxo-ferryl radicals, respectively. Each experiment was performed in triplicate with and without propofol or vitamin E at concentrations between 10(-5) and 10(-4) M. Lipid peroxidation was quantified by gas chromatography measurement of the pentane released (nmoles) from lipid decomposition. In each condition, a significant dose-response relationship was found between the release of pentane and the concentration of either propofol or vitamin E. The antioxidant activities of both agents were similar but significantly higher against the hydroxyl than the ferryl and oxo-ferryl radicals. The study suggests that propofol could be beneficial as an anesthetic or sedative drug in patients presenting pathologies associated with free radical reactions. [less ▲]

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See detailEffect Of Propylene Glycol Supplementation Around Parturition On Milk Yield, Reproduction Performance And Some Hormonal And Metabolic Characteristics In Dairy Cows
Formigoni, A.; Cornil, Mc.; Prandi, A. et al

in Journal of Dairy Research (1996), 63(1),

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See detailEffect of Prostaglandins Pge2 and Pgf Alpha 2 on the Mean Plaque Size of Bovine Herpesvirus 1
Thiry, Etienne ULg; Mignon, Bernard ULg; Thalasso, F. et al

in Annales de Recherches Vétérinaires = Annals of Veterinary Research (1988), 19(4), 291-293

The effect of prostaglandins PGE2 and PGF alpha 2 on infectious bovine rhinotracheitis (IBR) virus (bovine herpesvirus 1; BHV-1) was studied by using the measurement of the mean size of plaques produced ... [more ▼]

The effect of prostaglandins PGE2 and PGF alpha 2 on infectious bovine rhinotracheitis (IBR) virus (bovine herpesvirus 1; BHV-1) was studied by using the measurement of the mean size of plaques produced in cell culture by IBR/Cu5 strain. Three concentrations (0.1, 1 and 10 micrograms/ml) of prostaglandins, PGE2 and PGF alpha 2 were used. Each prostaglandin provoked an increase in the mean plaque size when compared to control plaques, at the concentrations 1 and 10 micrograms/ml for PGE2 and 10 micrograms/ml for PGF alpha 2. [less ▲]

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See detailEffect of protective compounds on the survival, electrolyte leakage and lipid degradation of freeze-dried Weissella paramesenteroides LC11 during storage.
Yao, Amenan Anastasie ULg; Wathelet, Bernard ULg; Thonart, Philippe ULg

in Journal of Microbiology and Biotechnology (2009), 19(8), 810-817

The effect of cryoprotectants (maltodextrin+glycerol) and cryoprotectants+antioxidant [ascorbic acid and/or butylated hydroxytoluene (BHT)] mixtures on the survival, electrolyte leakage, and lipid ... [more ▼]

The effect of cryoprotectants (maltodextrin+glycerol) and cryoprotectants+antioxidant [ascorbic acid and/or butylated hydroxytoluene (BHT)] mixtures on the survival, electrolyte leakage, and lipid degradation of freeze-dried Weissella paramesenteroides LC11 during storage was investigated and compared with that of the control (cells without additives) over a 90-day storage period at 4 or 20 degrees in glass tubes with water activity (a(w)) of 0.23. The survival, electrolyte leakage, and lipid degradation were evaluated through colony counts, electrical conductivity, and thiobarbituric acid reactive substances (TBARS) content, respectively. The fatty acids composition was determined by gas chromatography, in both the total lipid extract and the polar lipid fraction, and compared with that of the control after the 90-day storage period. As the storage proceeded, increases in leakage value and TBARS content, as well as a decrease in viability, were observed. After 90 days of storage, the major fatty acids found in both the total lipid extract and the polar lipid fraction were palmitic (16:0), palmitoleic (16:1), stearic (18:0), oleic (18:1), linoleic (18:2), and linolenic (18:3) acids. The survival, leakage value, TBARS content and 18:2/16:0 or 18:3/16:0 ratio were the greatest for the protected strain held at 4 degrees . Cells with the cryoprotectants+BHT mixture showed the highest percentage of survival and 18:2/16:0 or 18:3/16:0 ratio in both lipid extracts, as well as the lowest leakage value and TBARS content after the 90-day storage period. Drying cells with the cryoprotectants+BHT mixture considerably slowed down polar lipid degradation and loss of membrane integrity, resulting in improved viability during storage. [less ▲]

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See detailEffect of protein-supplemented fasting on metabolic and hormonal responses to epinephrine infusion in obese subjects.
Scheen, André ULg; Cession-Fossion, A.; Scheen, Myriam ULg et al

in Hormone & Metabolic Research (1982), 14(5), 240-5

The present study aimed at investigating the effects of an epinephrine (EPI) intravenous infusion (10 micrograms/min for 30 min) in normal subjects and in obese patients before and after 13 days of ... [more ▼]

The present study aimed at investigating the effects of an epinephrine (EPI) intravenous infusion (10 micrograms/min for 30 min) in normal subjects and in obese patients before and after 13 days of protein-supplemented fasting (PSF, 70 g protein/day). Blood glucose, plasma free fatty acids (FFA), lactate, insulin (IRI) and glucagon were determined before, during (15, 30 min) and after (+30 and +60 min) the EPI infusion. 1. When compared to lean control subjects, obese patients exhibited a less marked rise in blood glucose and a more important increase in plasma FFA, EPI infusion decreased IRI plasma levels in normals but not in the obese. Plasma glucagon was lower in the obese under basal conditions and their A cell reactivity to EPI was clearly reduced. 2. Comparison of the results obtained in obese patients before and after PSF revealed that EPI-induced blood glucose rise was not altered despite lower basal values after PSF. Plasma lactate response was impaired, probably because of the depletion in muscle glycogen. Reduction in basal plasma IRI was associated with a significantly higher FFA mobilization. Abnormally low basal EPI-stimulated glucagon concentrations persisted after PSF despite concomitant reductions in blood glucose and plasma IRI. [less ▲]

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See detailEffect of protein-supplemented fasting on the fuel-hormone response to prolonged exercise in obese subjects.
Scheen, André ULg; Luyckx, A. S.; Fossion, A. et al

in International Journal of Obesity & Related Metabolic Disorders (1983), 7(4), 327-37

This study aimed at investigating the influence of protein-supplemented fasting (PSF) on the tolerance and the fuel-hormone response to endurance exercise in the severely obese subject. For this purpose ... [more ▼]

This study aimed at investigating the influence of protein-supplemented fasting (PSF) on the tolerance and the fuel-hormone response to endurance exercise in the severely obese subject. For this purpose, eight obese men (27 +/- 2 yr, 182 +/- 7 per cent of ideal body weight) exercised on a horizontal treadmill (4 km/h) during 3 h before and after 13 d of PSF (Alburone, 70 g protein/day). Because of the 8.9 +/- 0.7 kg weight loss and the corresponding lower energy cost, exercise oxygen consumption decreased from 1.6 +/- 0.1 (before PSF) to 1.4 +/- 0.1 l/min (after PSF). In contrast, mean exercise heart rate was identical (119 +/- 5/min) in both conditions, resulting in a lower oxygen pulse after PSF. The mean respiratory quotient measured during exercise was lower after PSF (0.72 +/- 0.01 vs 0.75 +/- 0.01 2 P less than 0.05), thus demonstrating a higher fat utilization. This was supported by a higher exercise-induced plasma free fatty acid (FFA) mobilization after PSF (delta plasma FFA: + 675 +/- 101 vs + 376 +/- 121 mumol/l, 2 P less than 0.05). This metabolic adaptation mainly results from two mechanisms: a significantly lower plasma IRI at rest and during exercise after PSF (5.7 +/- 0.8 vs 11.4 +/- 1.4 microunits/ml, 2 P less than 0.001); and a lower basal blood glucose (4.2 +/- 0.2 vs 4.6 +/- 0.1 mmol/l) and an earlier decrease of glucose (30th vs 90th min) during exercise after PSF, suggesting a relative depletion of the carbohydrates stores. The lipolytic hormones (glucagon, epinephrine, norepinephrine, cortisol, growth hormone) did not significantly increase during exercise after PSF when compared to exercise before PSF; thus, their role in the enhanced FFA mobilization appears less important. Only two of our eight subjects were unable to achieve the third hour of exercise after PSF; however, no major clinical events or electrocardiographical disturbances were observed in any of the eight subjects. In conclusion, moderate exercise can be tolerated at least for 2 h during PSF when appropriate fluid, mineral and vitamin therapy is given. Under these conditions it induces a preferential utilization of fat-derived substrates and selectively augments fat mobilization which favors weight loss. For these reasons, moderate exercise can be recommended under strict medical supervision as part of all weight reduction therapy. [less ▲]

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See detailEffect of proteose-peptone addition on some physico-chemical characteristics of recombined dairy creams
Vanderghem, Caroline ULg; Danthine, Sabine ULg; Blecker, Christophe ULg et al

in International Dairy Journal (2007), 17(8), 889-895

The effect of the addition of the total proteose-peptone (TPP) fraction on some physico-chemical properties of recombined cream was studied. Oil-in-water emulsions, 30% or 20% (w/w) fat, were prepared ... [more ▼]

The effect of the addition of the total proteose-peptone (TPP) fraction on some physico-chemical properties of recombined cream was studied. Oil-in-water emulsions, 30% or 20% (w/w) fat, were prepared using only the dairy components buttermilk, milkfat and TPP. The effect of different concentrations of TPP on droplet size, creaming stability, flow behaviour, viscosity and whippability of recombined creams was tested. Of the different creams, those containing 2% (w/w) or more TPP were more viscous, showed different flow behaviour, and had improved stability and whippability compared with the other creams. The modifications in physico-chemical properties appeared to be driven by changes in particle size distribution caused by droplet aggregation. The percentage of fat also influenced the properties of the final product. It may therefore be possible to obtain desirable modifications in recombined cream using only dairy ingredients. (C) 2006 Elsevier Ltd. All rights reserved. [less ▲]

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See detailThe effect of race training on biochemical bone markers in young thoroughbreds
Carstanjen, B; Lepage, OM; Sulon, J et al

in Proceedings of the 13th annual scientific meeting of the ECVS (2003)

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See detailEffect of raingage density, position and interpolation on rainfall-discharge modelling
Ly, Sarann ULg; Sohier, Catherine ULg; Charles, Catherine ULg et al

in Geophysical Research Abstracts (2012), 14(EGU2012), 2592

Precipitation traditionally observed using raingages or weather stations, is one of the main parameters that has direct impact on runoff production. This pPrecipitation data requires a preliminary spatial ... [more ▼]

Precipitation traditionally observed using raingages or weather stations, is one of the main parameters that has direct impact on runoff production. This pPrecipitation data requires a preliminary spatial interpolation prior to hydrological modeling. The accuracy of modelling result is determined bydepends on the accuracy of the interpolated spatial rainfall which differs according to different interpolation methods. The accuracy of the interpolated spatial rainfall is usually determined by cross-validation method. The objective of this study is to assess the different interpolation methods of daily rainfall at the watershed scale through hydrological modelling and to explore the best methods that provides a good long term simulation. Four versions of geostatistics: Ordinary Kriging (ORK), Universal Kriging (UNK), Kriging with External Dridft (KED) and Ordinary Cokriging (OCK) and two types of deterministic methods: Thiessen polygon (THI) and Inverse Distance Weighting (IDW) are used to produce 30-year daily rainfall inputs for a distributed physically-based hydrological model (EPIC-GRID). This work is conducted in the Ourthe and Ambleve nested catchments, located in the Ardennes hilly landscape in the Walloon region, Belgium. The total catchment area is 2908 km², lies between 67 and 693 m in elevation. The multivariate geostatistics (KED and OCK) are also used by incorporating elevation as external data to improve the rainfall prediction. This work also aims at analysing the effect of different raingage densities and position used for interpolation, on the stream flow modelled to get insight in terms of the capability and limitation of the geostatistical methods. The number of raingage varies from 70, 60, 50, 40, 30, 20, 8 to 4 stations located in and surrounding the catchment area. In the latter case, we try to use different positions: around the catchment and only a part of the catchment. The result shows that the simple method like THI fails to capture the rainfall and to produce good flow simulation when using 4 raingages. The KED and UNK are comparable to other methods for a raingage case that in which stations are located around the catchment area, especially in the high elevation catchment but the worst methods for other raingage position cases where the rainfall stations are located only at a part and mostly outside of the catchment area. However, three methods (IDW, ORK and OCK) can overcome this problem since they are more robust and can provide good performance of simulation in all raingage densities. When using 70, 60, 50, 40, 30, 20, 8 raingages in the catchment area (2908 km²), no substantial differences in model performance are observed. [less ▲]

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See detailEffect of raloxifene and alendronate on bone mineral density and bone turnover markers in postmenopausal women with osteoporosis
Johnell, O; Lu, Y; Seeman, E et al

in Osteoporosis International (2000), 11(S2), 184

Detailed reference viewed: 5 (3 ULg)