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See detailEffect of bovine Azawak colostrum administration on plasma protein profile in red kid.
Abdou, Harouna ULg; Marichatou, Hamani; Beckers, Jean-François ULg et al

Poster (2012, October 11)

This study evaluated the impact of heterologous Azawak colostrum administration on plasma protein profile in red kids from Niger. Forty (40) newborn kids were affected to one of two treatments: control ... [more ▼]

This study evaluated the impact of heterologous Azawak colostrum administration on plasma protein profile in red kids from Niger. Forty (40) newborn kids were affected to one of two treatments: control group (access to water and the mother) and colostrum group (access to the mother, water and additional 50 ml of colostrum Azawak/animal the day of birth, then 25ml/animal/day from the 2nd to 15th day). Blood samples (10ml/animal) were obtained at the age of 10 and 30 days by jugular puncture into EDTA vacutainer tubes. The quantification of total protein was performed by the Biuret method. The agarose gel electrophoresis was used to determine serum levels of albumin, ɑ-globulin, β1-globulin, β2-globulin, γ-globulin and finally the albumin/globulin ratio. In general, the average concentrations of these proteins obtained at both ages reached higher values in colostrum than in control group. At day 10, the colostrum group tended to show (P <0.07) higher levels for ɑ-globulin and showed higher values (P <0.04) for β1-globulin. At day 30, total protein and β2-globulins were higher in colostrum group. The administration of heterologous colostrum in kid seems to have positive effects on some plasma parameters. It would be worth to discriminate the plasma proteins derived from bovine and maternal colostra. [less ▲]

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See detailEffect of bovine colostrum administration on plasma protein profile, growth, and survival in Red kid.
Abdou, Harouna ULg; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Small Ruminant Research (2013), 117

This study evaluated the effect of colostrum from Azawak cows on plasma protein profile, 24 growth, and survival in Red kids from Niger. Forty (40) newborn kids were allocated to one 25 of two treatment ... [more ▼]

This study evaluated the effect of colostrum from Azawak cows on plasma protein profile, 24 growth, and survival in Red kids from Niger. Forty (40) newborn kids were allocated to one 25 of two treatment-groups: control (free access to water and the mother) and colostrum (free 26 access to water and the mother, but with additional 50 mL of colostrum/animal/day of birth 27 and 25 mL/animal/day from the 2nd to 15th day of age). Blood samples were collected into 28 EDTA vacutainer tubes by jugular puncture at 10 and 30 days of age. Total protein was 29 quantified by the Biuret method. The agarose gel electrophoresis was used to determine the 30 serum levels of albumin, -globulin, β1-globulin, β2-globulin, γ-globulin and the 31 albumin/globulin ratio. The animals from the colostrum group showed higher body weight 32 and average daily gain when compared to the control group (P < 0.001). The average 33 concentration in protein at the both sampling times reached higher values in the colostrum 34 than in the control group. At D10, the colostrum group tended (P < 0.07) to show higher 35 levels of -globulin and had higher values (P < 0.05) for β1-globulin. At D30, total protein 36 and β2-globulins were higher in colostrum group. Colostrum from Azawak cows seems to 37 have positive effects on some plasma proteins levels and on growth rate in Red kids. [less ▲]

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See detailEffect of bovine colostrum intake on growth, reproductive parameters and survival in red kids
Harouna, Abdou; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Journal of Animal Physiology & Animal Nutrition (in press)

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition ... [more ▼]

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition, fertility, fecundity, prolificacy) and mortality rate among red kids. The study was conducted at the goat farm secondary centre of Maradi in Niger from September 2010 to September 2011. The control animals (n = 20) were left with their mother, while the treatment animals (n = 20) received in addition 50 ml/animal/day of bovine colostrum at birth and 15 ml/animal/day from d2 to d15. Weight was measured weekly from birth to d365. Mortalities were also recorded over the same period. For reproductive parameters, observations began at weaning (d197). Growth rate was higher (p < 0.001) in supplemented animal, and the treatment effects on ADG were observed up to 150 day after the end of supplementation. A similar long-lasting trend was also observed in relation to the mortality rate (25% for ColG vs. 55% for ConG; p = 0.05). The age at first kidding tended to be lower in the treated group (13.8 0.7 vs. 14.1 0.8 month; p < 0.1). In conclusion, mild bovine colostrum supplementation induces a long-lasting positive impact on growth rate and to a lower extent on reproduction parameters and survival rate. [less ▲]

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See detailEffect of bovine colostrum on the serum insulin-like growth factor-I (IGF-I), the IGF binding proteins-2 and -3 and the thyroid hormones in weaning piglets
Boudry, Christelle ULg; Dehoux, Jean-Paul; Colinet, Frédéric ULg et al

in Archiv Tierzucht (2010), 53(6), 675-688

This study examined the effect of a bovine colostrum supplementation on growth performance, feed intake and the hormonal response of piglets at weaning. Ninety-six newly-weaned piglets were assigned for ... [more ▼]

This study examined the effect of a bovine colostrum supplementation on growth performance, feed intake and the hormonal response of piglets at weaning. Ninety-six newly-weaned piglets were assigned for four weeks to one of the two treatments: Control (diet with bovine milk whey) and Colostrum (diet with bovine colostrum whey) treatments. The supplements were incorporated in a commercial diet at 20 g/kg during the first 2 weeks after weaning and lowered to 10 g/kg for the next 2 weeks. Body weight and feed intake were measured weekly. Blood samples were taken weekly for determination of circulating IGF-I, its binding proteins and the thyroid hormones (T3 and T4). During the first week of the trial, the Colostrum-fed piglets presented improved growth performance, feed intake and feed efficiency and a higher concentration in circulating IGF-I (+ 15 %) compared to the Control piglets. In both treatments, the circulating thyroid hormones were reduced by weaning and the levels measured at weaning were recovered earlier by the Colostrum-fed piglets compared to the Control group (P < 0.05). It is concluded that hormonal response observed after the bovine colostrum supplementation is, at least in part, consequent of the positive action of bovine colostrum on the feed intake. [less ▲]

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See detailEffect Of Bovine Colostrum Supplementation On Cytokine mRNA Expression In Weaned Piglets
Boudry, Christelle ULg; Buldgen, André; Portetelle, Daniel ULg et al

in Livestock Science (2007), 108(1-3), 295-298

The aim of this study was to evaluate the influence of a bovine colostrum supplementation on the immune Th1/Th2 response in weaned piglets. After weaning at 21 days, 21 piglets were fed daily ad libitum ... [more ▼]

The aim of this study was to evaluate the influence of a bovine colostrum supplementation on the immune Th1/Th2 response in weaned piglets. After weaning at 21 days, 21 piglets were fed daily ad libitum with a starter diet supplemented for 3 weeks with 0, 1 or 5 g of bovine colostrum. Growth performances were measured weekly. Spleen and gut-associated lymphoid tissues (GALT) (ileal Peyer’s patch (iPP), jejunum wall (JW) and mesenteric lymph nodes (MLN)) biopsies were collected on each piglet after the 3 weeks treatment and analyzed for their cytokine mRNA expression (IL-2, IL-4, IL-10, IL-12 and IFN) by RT-PCR. Growth performances were not affected by bovine colostrum (P > 0.05). In the colostrum groups, the iPP cells showed higher IL-4, IL-10 and IL-12 cytokine levels (P < 0,05), associated with a decrease of IFN-γ (P < 0,01) and no effect on IL-2 production (P > 0,05). IL-10, IL-2 and IL-12 productions increased (P < 0,05) in MLN, with no effect on IFN-γ and IL-4 levels (P > 0,05). The IL-12 production was also increased (P < 0,01) in JW cells with no modification for the other cytokine. No modification of cytokine production was observed in the spleen (P > 0,05). These results suggest an immunomodulatory effect of bovine colostrum on the GALT which answered by producing, at different levels, both Th1 pro-inflammatory cytokines - IL-2, IFN-γ and IL-12 - and Th2 anti-inflammatory cytokines - IL-4 and IL-10. This bipolarity of the Th1/Th2 response protects the weaned piglets from both allergic (food) as well as infectious (pathogens) diseases. [less ▲]

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See detailEffect Of Bovine Colostrum Supplementation On Cytokine mRNA Expression In Weaned Piglets
Boudry, Christelle ULg; Buldgen, André; Portetelle, Daniel ULg et al

in 10th International symposium on digestive physiology in pigs (2006, May)

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See detailEffect of bovine colostrums of 1st, 2nd and 3rd milking on growth performance and the immune system of newly-weaned piglets after an E. coli LPS challenge
Gauthier, Vincent ULg; Boudry, Christelle ULg; Buldgen, André

in Book of the Abstracts of the 60th Annual Meeting of the European Association for Animal Production (2009, August)

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See detailEffect of breed on Doppler echocardiographic measurements in equids
Al Haidar, A; Sandersen, Charlotte ULg; Van Erck, Emmanuelle et al

in Proceedings of the 3rd Annual Congress of the European College of Equine Internal Medicine (ECEIM) (2009)

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See detailEffect of breed, age and sex on selenium content of dromedary
Sahraoui, Naima; Boudjenah, Saliha; Dotreppe, Olivier ULg et al

in Sahraoui Journal of Camelid Science (2013), 6

The dromedary camel is able to produce meat and milk in arid conditions and its production is appreciated by the autochthon population. The aim of this study was to determine the selenium concentration in ... [more ▼]

The dromedary camel is able to produce meat and milk in arid conditions and its production is appreciated by the autochthon population. The aim of this study was to determine the selenium concentration in 61 Longissimus dorsi muscle samples representing three Algerian camel breeds (Tergui, Sahraoui or Naili breeds), the age of the selected camels ranged between 8 months and 13 years old. The muscle samples were collected from the slaughterhouse of Ouargla (South East Algeria) representing 41 males and 20 female. The average content of selenium was 0.216 mg.kg-1of wet tissue, which is higher than values currently reported in most ruminants. The level of Se was not influenced by age and sex. However, Tergui breed contained significantly higher selenium than other breeds, which may be due to diet composition intake. In conclusion, the meat from camels in Algeria is a good source of selenium, assessing its nutritional interest for human. [less ▲]

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See detailEffect of breed, sex, age and body weight on Echocardiographic Measurements in the Equine Species
Al Haidar, Ali; Farnir, Frédéric ULg; Deleuze, Stefan ULg et al

in Research in Veterinary Science (2013), In press

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age ... [more ▼]

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age and body weight (BW) on echocardiographic measurements in the equine species. Echocardiography was performed on 212 ponies or horses of various breeds, aged from 1 day to 37 years old (mean ± SD: 7.8 ± 5.8 years), BW 38-890 kg (mean ± SD: 421 ± 133 Kg), and free of cardiac disease. Fifty of those animals aged from 2 months to 35 years old (mean ± SD: 11.6 ± 6.4 years old); BW 77-662 kg (mean ± SD: 436 ± 135 kg) were also examined using the pulsed-wave Doppler mode. Standard two-dimensional and M-mode echocardiography were performed on all animals. Standard pulsed-wave Doppler examination of each cardiac valve was performed on the 50 first examined animals. Data were analysed using a general linear model including the effect of sex, age, breed and BW after logarithmic transformation of the data. Therefore, the same analysis was performed separately on animals aged  2 years-old and on older animals. All dimensional echocardiographic measurements were significantly affected by BW and most of them were significantly affected by breed, but not by sex. Only the aortic and the pulmonary artery internal diameter were significantly affected by age. None of the Doppler measurements were significantly affected by the tested variables. In conclusion, in the equine species, dimensional echocardiographic reference values should be established using regression equations as a function of BW, which could increase the diagnostic value of this leading technique in equine cardiology. Breed could also have an effect on those measurements. [less ▲]

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See detailEffect of bronchoalveolar lavage on lung function in healthy cats assessed by plethysmography
Kirschvink, N.; Vincke, G.; Marville, M. et al

in 20th Veterinary Comparative Respiratory Society - Boston, Massachussetts - USA - Octobre 2002 (2002, October)

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See detailEffect of butorphanol tartrate on shock-related discomfort during internal atrial defibrillation.
Timmermans, Carl; Rodriguez, L M; Ayers, G M et al

in Circulation (1999), 99(14), 1837-42

BACKGROUND: In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of ... [more ▼]

BACKGROUND: In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of this new treatment mode. METHODS AND RESULTS: In a double-blind, placebo-controlled manner, the effect of intranasal butorphanol, an opioid, was evaluated in 47 patients with the use of a step-up internal atrial defibrillation protocol (stage I). On request, additional butorphanol was administered and the step-up protocol continued (stage II). Thereafter, if necessary, patients were intravenously sedated (stage III). After each shock, the McGill Pain Questionnaire was used to obtain a sensory (S), affective (A), evaluative (E), and total (T) pain rating index (PRI) and a visual analogue scale analyzing pain (VAS-P) and fear (VAS-F). For every patient, the slope of each pain or fear parameter against the shock number was calculated and individual slopes were averaged for the placebo and butorphanol group. All patients were cardioverted at a mean threshold of 4.4+/-3.3 J. Comparing both patient groups for stage II, the mean slopes for PRI-T (P=0.0099), PRI-S (P=0.019), and PRI-E (P=0.015) became significantly lower in the butorphanol group than in the placebo group. Comparing patients who received the same shock intensity ending stage I and going to stage II, in those patients randomized to placebo the mean VAS-P (P=0.023), PRI-T (P=0. 029), PRI-S (P=0.030), and PRI-E (P=0.023) became significantly lower after butorphanol administration. CONCLUSIONS: During a step-up internal atrial defibrillation protocol, intranasal butorphanol decreased or stabilized the value of several pain variables and did not affect fear. Of the 3 qualitative components of pain, only the affective component was not influenced by butorphanol. The PRI evaluated pain more accurately than the VAS. [less ▲]

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See detailEffect of Calcitonin on Bone Mass and Fracture Rates
Reginster, Jean-Yves ULg

in American Journal of Medicine (1991), 91(5B), 19-22

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See detailEffect of candesartan cilexetil and angiotensin-converting enzyme inhibitor therapy on treatment adherence in hypertension
Krzesinski, Jean-Marie ULg; Lins, R.; Vandenhoven, G. et al

in Journal of Hypertension (2001), 19

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See detailEffect of carbohydrate composition in barley and oat cultivars on microbial ecophysiology and the proliferation of Salmonella enterica in an in vitro model of the porcine gastrointestinal tract
Pieper, Robert; Bindelle, Jérôme ULg; Rossnagel, Brian et al

in Applied and Environmental Microbiology (2009), 75(22), 7000-7016

The influence of the carbohydrate (CHO) composition of cereal cultivars on microbial ecophysiology was studied using an in vitro model of the porcine gastrointestinal tract. Ten hull-less barley cultivars ... [more ▼]

The influence of the carbohydrate (CHO) composition of cereal cultivars on microbial ecophysiology was studied using an in vitro model of the porcine gastrointestinal tract. Ten hull-less barley cultivars, six barley cultivars with hulls, six oat cultivars, and six oat groats that differed in beta-glucan, nonstarch polysaccharide (NSP), and starch contents and starch type were hydrolyzed enzymatically and incubated for 72 h with pig feces. Fermentation kinetics were modeled, and microbial compositions and short-chain fatty acid (SCFA) profiles were analyzed using terminal restriction fragment length polymorphism and gas chromatography. Cluster analysis and canonical ordination revealed different effects on fermentation and microbial ecology depending on the type of CHO and cultivar. First, in cultivars of barley with hulls and oats, the cellulose and insoluble NSP contents (i) increased Ruminococcus flavefaciens-like and Clostridium xylanolyticum-like phylotypes, (ii) increased acetate production, and (iii) decreased fermentation activity. Second, in hull-less barley cultivars the beta-glucan, amylose, amylopectin, crude protein, and soluble NSP contents determined the microbial community composition and activity as follows: (i) the amylose contents of the hull-less barley varieties increased the butyrate production and the abundance of Clostridium butyricum-like phylotypes, (ii) the beta-glucan content determined the total amounts of SCFA, and (iii) the amylopectin and starch contents affected the abundance of Clostridium ramosum-like phylotypes, members of Clostridium cluster XIVa, and Bacteroides-like bacteria. Finally, the effect of CHO on proliferation of Salmonella enterica in the model was determined. Salmonella cell counts were not affected, but the relative proportion of Salmonella decreased with hull-less barley cultivars and increased with oat cultivars as revealed by quantitative PCR. Our results shed light on the complex interactions of cereal CHO with intestinal bacterial ecophysiology and the possible impact on host health. [less ▲]

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See detailEffect of carbon doping on the structure of amorphous GeTe phase change material
Ghezzi, G. E.; Raty, Jean-Yves ULg; Maitrejean, S. et al

in Applied Physics Letters (2011), 99(15), 1519063-15190631519063

Carbon-doped GeTe is a promising material for use in phase change memories since the addition of C increases the stability of the amorphous phase. By combining x-ray total scattering experiments and ab ... [more ▼]

Carbon-doped GeTe is a promising material for use in phase change memories since the addition of C increases the stability of the amorphous phase. By combining x-ray total scattering experiments and ab initio molecular dynamics, we show that carbon deeply modifies the structure of the amorphous phase through long carbon chains and tetrahedral and triangular units centered on carbon. A clear signature of these units is the appearance of an additional interatomic distance, around 3.3 Aring in the measured pair distribution function. Besides, the first Ge-Ge and Ge-Te distances are almost not affected by doping. [less ▲]

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See detailEffect of cardiac resynchronization therapy on functional mitral regurgitation in heart failure.
Lancellotti, Patrizio ULg; MELON, Pierre ULg; SakalihasanN, Natzi ULg et al

in American Journal of Cardiology (2004), 94(11), 1462-5

Cardiac resynchronization therapy (CRT) reduces functional mitral regurgitation (MR) at rest. This study assessed exercise-induced changes in MR in patients with heart failure who were helped by CRT. The ... [more ▼]

Cardiac resynchronization therapy (CRT) reduces functional mitral regurgitation (MR) at rest. This study assessed exercise-induced changes in MR in patients with heart failure who were helped by CRT. The determinants of these exercise-induced changes in MR were analyzed in asynchronous and resynchronized left ventricles. [less ▲]

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See detailEffect of carprofen treatment following experimentally induced Escherichia coli mastitis in primiparous cows.
Vangroenweghe, F.; Duchateau, L.; Boutet, Philippe ULg et al

in Journal of Dairy Science (2005), 88(7), 2361-2376

Acute Escherichia coli mastitis is one of the major sources of economic loss in the dairy industry due to reduced milk production, treatment costs, discarded milk, and occasional fatal disease ... [more ▼]

Acute Escherichia coli mastitis is one of the major sources of economic loss in the dairy industry due to reduced milk production, treatment costs, discarded milk, and occasional fatal disease. Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used as adjunctive therapy to antibiotics. The objective of the current study was to evaluate the effect of carprofen treatment following infusion of Escherichia coli into the mammary glands of primiparous cows during the periparturient period. Severity of mastitis was scored based on the average milk production in the uninfected quarters on d +2 postinoculation and a clinical severity score. Carprofen was administered intravenously at 9 h postchallenge, when clinical signs of mastitis appeared. In previous work, efficacy of NSAIDs was mainly evaluated using clinical symptoms. In the present study, the effect of carprofen on innate immune response was also assessed by quantification of inflammatory mediators. All primiparous cows reacted as moderate responders throughout the experimental period. Primiparous cows were intramammarily inoculated with 1 x 10(4) cfu of E. coli P4:O32 in 2 left quarters. Analysis of blood and milk parameters, including IL-8, complement component C5a, lipopolysaccharide-binding protein (LBP), soluble CD14, prostaglandin E2, and thromboxane B2 was performed from d 0 to d +6 relative to intramammary inoculation. Rectal temperature in carprofen-treated animals was lower than in control animals at 3 and 6 h posttreatment. Treatment also restored the decreased reticulorumen motility that occurs during E. coli mastitis to preinfection levels faster than in control animals. Carprofen treatment resulted in an earlier normalization of the clinical severity score. Eicosanoid (prostaglandin E2 and thromboxane B2) production in milk tended to be inhibited by carprofen. No significant differences in the kinetic patterns of somatic cell count, IL-8, complement component C5a, LBP, and soluble CD14 were observed. In conclusion, carprofen treatment improved general clinical condition by effective antipyrexia and restoration of reticulorumen motility but did not significantly inhibit eicosanoid production. Carprofen treatment did not result in a significant decrease of chemotactic inflammatory mediators, IL-8 and C5a, and early innate immune molecules, sCD14 and LBP. Therefore, major modulatory effects from NSAID administration were not observed in this mastitis model, although a larger study might confirm some apparent trends obtained in the present results. [less ▲]

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See detailEffect of catechins and citrus flavonoids on invasion in vitro.
Bracke, M.; Vyncke, B.; Opdenakker, G. et al

in Clinical & Experimental Metastasis (1991), 9(1), 13-25

Catechins, a group of flavonoid molecules, inhibit invasion of mouse MO4 cells into embryonic chick heart fragments in vitro. The anti-invasive effects can be ranked as follows: (+)-catechin greater than ... [more ▼]

Catechins, a group of flavonoid molecules, inhibit invasion of mouse MO4 cells into embryonic chick heart fragments in vitro. The anti-invasive effects can be ranked as follows: (+)-catechin greater than (-)-epicatechin greater than 3-O-methyl-(+)-catechin greater than 3-O-palmitoyl-(+)-catechin. Most of the catechins are unstable in cell culture media, and their spontaneous rearrangement products tend to bind to extracellular matrix (ECM). Due to these interactions proteases such as tissue-type plasminogen activator (t-PA) are linked to the ECM glycoprotein laminin. This leads to a partial inactivation of the enzyme. Within the group of catechins we found a positive correlation between anti-invasive activity and linking of t-PA to laminin. Citrus flavonoids are also anti-invasive in vitro (tangeretin greater than nobiletin greater than hesperidin = naringin). However, these stable molecules show poor affinity for ECM, and do not link enzymes to laminin. These data suggest that catechins and citrus flavonoids inhibit invasion in vitro by different mechanisms. [less ▲]

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