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See detailThe effect of treadmill training on motor recovery after a spinal cord injury (SCI) in the adult rat.
Oliveira, C.; Multon, S.; Scholtes, Félix ULg et al

Conference (2001, May)

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See detailEffect of treatment with octreotide on the morphology of growth hormone secreting pituitary adenomas : study of 24 cases.
Beckers, Albert ULg; Kovacs, K.; Horvwarth, E. et al

in Endocrine Pathology (1991), 2(3), 123-131

Twenty-four acromegalic patients were treated with octreotide subcutaneously for periods of 3 to 6 weeks (group I, 12 cases) or 6 months (group II, 12 cases) before transsphenoidal surgery. Radiological ... [more ▼]

Twenty-four acromegalic patients were treated with octreotide subcutaneously for periods of 3 to 6 weeks (group I, 12 cases) or 6 months (group II, 12 cases) before transsphenoidal surgery. Radiological studies performed in 19 patients before and at the end of this treatment period revealed no changes in 8 cases. In 8 other cases, a slight reduction in tumorsize was observed, and in 3 cases an important shrinkage was documented. At surgery, the adenomatous tissue appeared softer than in nonpretreated patients, facilitating the operation. Pathological examination revealed widening of perivascular spaces with accumulation of fibrous tissue and more crinophagy than in nonpretreated patients but failed to reveal morphologically pronounced cell involution as observed in prolactin-producing adenomas treated with dopamine agonists. No significant difference in frequency or extent of cellular changes was noted between the two groups. These morphological findings seem to be more consistent with a functional inhibition of growth hormone release than with cellular alterations induced by octreotide. [less ▲]

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See detailEffect of trenbolone acetate and zeranol on LH and testosterones responses to LHRH in young double-muscled Belgian bulls
Renaville, Robert ULg; Fabry, Jules

in 2th World Congress on Genetics Applied to Livestock Production (1982)

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See detailEffect of trenbolone acetate associated with 17á-oestradiol on reproductive performances of young growing fattening bulls
Istasse, Louis ULg; Evrard, Pierre; Hanzen, Christian ULg et al

in Journal of Animal Physiology & Animal Nutrition (1988), 59

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See detailEffect of trenbolone acetate associated with 17ß-oestradiol on reproductive performances of young growing fattening bulls
Istasse, Louis ULg; Evrard, Pierre; Coignoul, Freddy ULg et al

in Journal of Animal Physiology & Animal Nutrition (1988), 59

Bulls were implanted with an ear pellet of trenbolone acetate and oestradiol in association. Some treated bulls produced a sperm without spermatozoa but there were no significant differences in ... [more ▼]

Bulls were implanted with an ear pellet of trenbolone acetate and oestradiol in association. Some treated bulls produced a sperm without spermatozoa but there were no significant differences in spermatozoa concentration and sperm quality between treated animals which produced a sperm with spermatozoa and control bulls. The scrotal circumference of the treated animals did not change over the experimental period while that of control bulls regularly increased. After a dynamic stimuation with luteinzing hormone releasing hormone, the luteinizing hormone concentrations did not change in the treated animals and the testosterone kinetic profiles were characterized by a low basal concentration and small peak heights. The microscopic evaluation of the testicles indicated a reduction in the percentage of seminiferous tubules with mature spermatozoa and a reduction in the number of Leydig cells in the islets. [less ▲]

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See detailThe effect of TRH on F waves recorded from antagonistic muscles in human subjects.
Delwaide, P. J.; Schoenen, Jean ULg

in Annals of Neurology (1985), 18(3), 366-7

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See detailEffect of tricyclic antidepressant drugs on the spontaneous activity of noradrenergic neurons
Scuvée-Moreau, Jacqueline ULg; Fischer, Paul; Dresse, Albert ULg

in Archives Internationales de Pharmacodynamie et de Thérapie (1978), 234(2), 344-345

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See detailThe effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study.
Tskitishvili, Ekaterine ULg; Nakamura, Hitomi; Kinugasa-Taniguchi, Yukiko et al

in American Journal of Obstetrics and Gynecology (2010), 203(4), 3646-36412

OBJECTIVE: The level of tumor-associated receptor-binding cancer antigen that is expressed on SiSo cells (RCAS1) is decreased significantly in preeclamptic pregnancies. We hypothesized that RCAS1 protein ... [more ▼]

OBJECTIVE: The level of tumor-associated receptor-binding cancer antigen that is expressed on SiSo cells (RCAS1) is decreased significantly in preeclamptic pregnancies. We hypothesized that RCAS1 protein gene silencing might affect blood pressure and proteinuria in pregnant mice. STUDY DESIGN: On postcoital day 7.5, pregnant imprinting control region mice were subjected to the transfer of small interfering RNA (siRNA) against RCAS1 protein into the uterine cavity with the use of a hemagglutinating virus Japan envelope. Scramble siRNA was used as a negative control. Blood pressure and urine albumin/creatinine measurements were performed. The effect of the transferred siRNA was examined in uterine samples on postcoital day 8.5 with the use of Western blotting and immunohistochemistry analyses. RESULTS: In the RCAS1 siRNA group, blood pressure significantly raised on postcoital days 9.5, 10.5, 11.5, and 15.5, whereas urine albumin/creatinine ratio was significantly increased on postcoital day 9.5 CONCLUSION: Our results suggest the importance of RCAS1 protein in the pathophysiologic condition of preeclampsia. [less ▲]

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See detailThe effect of turbulent mixing on g-modes spectrum of MS stars
Montalban Iglesias, Josefa ULg; Miglio, Andrea ULg; Eggenberger, P. et al

in Astronomische Nachrichten (2008), 329

Understanding transport processes inside stars is one of the main goals of asteroseismology. Chemical turbulent mixing can affect the internal distribution of μ near the energy generating core, having an ... [more ▼]

Understanding transport processes inside stars is one of the main goals of asteroseismology. Chemical turbulent mixing can affect the internal distribution of μ near the energy generating core, having an effect on the evolutionary tracks similar to that of overshooting. This mixing leads to a smoother chemical composition profile near the edge of the convective core, which is reflected in the behavior of the buoyancy frequency and, therefore, in the frequencies of gravity modes. We describe the effects of convective overshooting and turbulent mixing on the frequencies of gravity modes in B-type main sequence stars. In particular, the cases of p-g mixed modes in β Cep stars and high-order modes in SPBs are considered. [less ▲]

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See detailEffect of type 2 antiserotonergic agent on altered cardiovascular function of hyperdynamic sepsis in newborn calves
Desmecht, Daniel ULg; Linden, Annick ULg; Amory, Hélène ULg et al

in Proceedings of the 13th Comparative Respiratory Society Meeting (1994)

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See detailEffect of uncertainty in surface mass balance–elevation feedback on projections of the future sea level contribution of the Greenland ice sheet
Edwards, T.; Fettweis, Xavier ULg; Gagliardini, O. et al

in Cryosphere (The) (2014), 8

We apply a new parameterisation of the Greenland ice sheet (GrIS) feedback between surface mass balance (SMB: the sum of surface accumulation and surface ablation) and surface elevation in the MAR ... [more ▼]

We apply a new parameterisation of the Greenland ice sheet (GrIS) feedback between surface mass balance (SMB: the sum of surface accumulation and surface ablation) and surface elevation in the MAR regional climate model (Edwards et al., 2014) to projections of future climate change using five ice sheet models (ISMs). The MAR (Modèle Atmosphérique Régional: Fettweis, 2007) climate projections are for 2000–2199, forced by the ECHAM5 and HadCM3 global climate models (GCMs) under the SRES A1B emissions scenario. The additional sea level contribution due to the SMB–elevation feedback averaged over five ISM projections for ECHAM5 and three for HadCM3 is 4.3% (best estimate; 95% credibility interval 1.8–6.9%) at 2100, and 9.6% (best estimate; 95% credibility interval 3.6–16.0%) at 2200. In all results the elevation feedback is significantly positive, amplifying the GrIS sea level contribution relative to the MAR projections in which the ice sheet topography is fixed: the lower bounds of our 95% credibility intervals (CIs) for sea level contributions are larger than the "no feedback" case for all ISMs and GCMs. Our method is novel in sea level projections because we propagate three types of modelling uncertainty – GCM and ISM structural uncertainties, and elevation feedback parameterisation uncertainty – along the causal chain, from SRES scenario to sea level, within a coherent experimental design and statistical framework. The relative contributions to uncertainty depend on the timescale of interest. At 2100, the GCM uncertainty is largest, but by 2200 both the ISM and parameterisation uncertainties are larger. We also perform a perturbed parameter ensemble with one ISM to estimate the shape of the projected sea level probability distribution; our results indicate that the probability density is slightly skewed towards higher sea level contributions. [less ▲]

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See detailEffect of valsartan on the incidence of diabetes and cardiovascular events.
McMurray, John J; Holman, Rury R; Haffner, Steven M et al

in New England Journal of Medicine [=NEJM] (2010), 362(16), 1477-90

BACKGROUND: It is not known whether drugs that block the renin-angiotensin system reduce the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance. METHODS: In this double ... [more ▼]

BACKGROUND: It is not known whether drugs that block the renin-angiotensin system reduce the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance. METHODS: In this double-blind, randomized clinical trial with a 2-by-2 factorial design, we assigned 9306 patients with impaired glucose tolerance and established cardiovascular disease or cardiovascular risk factors to receive valsartan (up to 160 mg daily) or placebo (and nateglinide or placebo) in addition to lifestyle modification. We then followed the patients for a median of 5.0 years for the development of diabetes (6.5 years for vital status). We studied the effects of valsartan on the occurrence of three coprimary outcomes: the development of diabetes; an extended composite outcome of death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, hospitalization for heart failure, arterial revascularization, or hospitalization for unstable angina; and a core composite outcome that excluded unstable angina and revascularization. RESULTS: The cumulative incidence of diabetes was 33.1% in the valsartan group, as compared with 36.8% in the placebo group (hazard ratio in the valsartan group, 0.86; 95% confidence interval [CI], 0.80 to 0.92; P<0.001). Valsartan, as compared with placebo, did not significantly reduce the incidence of either the extended cardiovascular outcome (14.5% vs. 14.8%; hazard ratio, 0.96; 95% CI, 0.86 to 1.07; P=0.43) or the core cardiovascular outcome (8.1% vs. 8.1%; hazard ratio, 0.99; 95% CI, 0.86 to 1.14; P=0.85). CONCLUSIONS: Among patients with impaired glucose tolerance and cardiovascular disease or risk factors, the use of valsartan for 5 years, along with lifestyle modification, led to a relative reduction of 14% in the incidence of diabetes but did not reduce the rate of cardiovascular events. (ClinicalTrials.gov number, NCT00097786.) [less ▲]

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See detailEffect Of Variety And Harvest Date On Pectin Extracted From Chicory Roots (Cichorium Intybus L.)
Robert, Christelle; Happi Emaga, Thomas; Wathelet, Bernard ULg et al

in Food Chemistry (2008), 108(3),

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See detailEffect of Various 6-Dehydro-Corticosteroids, 9, 11-Dehydro-Doca and 9 Alpha-Fluoro-Doca on the Fluxes of Sodium and Potassium
Genard, P.; Palem-Vliers, M.; Christiaens, J. M. et al

in Archives Internationales de Physiologie et de Biochimie (1989), 97(2), 175-183

The introduction of a double bond at carbons 6 and 7 (6-dehydro-derivatives) of deoxycorticosterone acetate (DOCA), cortisol-21-acetate, 9 alpha-fluorocortisol-21-acetate (9 alpha-F-C-ac) and aldosterone ... [more ▼]

The introduction of a double bond at carbons 6 and 7 (6-dehydro-derivatives) of deoxycorticosterone acetate (DOCA), cortisol-21-acetate, 9 alpha-fluorocortisol-21-acetate (9 alpha-F-C-ac) and aldosterone-21-acetate substantially reduces affinity for Type II receptors but not for Type I receptors. Such a modification changes the effect of these steroids on urinary excretion of Na+ and K+. 6-Dehydro-derivatives will thus bind preferentially to receptor Type I inducing the retention of sodium and compete with mineralocorticoids for such receptors. The increase in both natriuresis and kaliuresis when corticosteroids and their 6-dehydro-derivatives are administered together may be interpreted as evidence for a Type II receptor mediation of those ion fluxes. The ionic changes are not mediated by the (Na+ + K+)-ATPase system. The fluoration at 9 and the dehydrogenation at C9C11 of DOCA result in a strong increase of binding to Type I receptor and of sodium retention. [less ▲]

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See detailEffect of various level of imbalance between energy ans nitrogen supplies on nitrogen metabolism in growing double-muscled Belgian Blue bulls.
Valkeners, Damien; Beckers, Yves ULg; Thewis, André ULg

in Proceeding of the British Society of Animal Science - Annual meeting (2004, April)

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See detailEffect Of Various Levels Of Imbalance Between Energy And Nitrogen Release In The Rumen On Microbial Protein Synthesis And Nitrogen Metabolism In Growing Double-Muscled Belgian Blue Bulls Fed A Corn Silage-Based Diet
Valkeners, Damien; Thewis, André ULg; Amant, Stéphanie et al

in Journal of Animal Science (2006), 84(4), 877-885

Seven double-muscled Belgian Blue bulls (initial BW: 341 ± 21 kg) with cannulas in the rumen and proximal duodenum were used in an incomplete replicated Latin square. The study examined the effect of ... [more ▼]

Seven double-muscled Belgian Blue bulls (initial BW: 341 ± 21 kg) with cannulas in the rumen and proximal duodenum were used in an incomplete replicated Latin square. The study examined the effect of imbalance between energy and N in the rumen on microbial protein synthesis and N metabolism by giving the same diet according to 3 different feeding patterns. The feed ingredients of the diet were separated into 2 groups supplying the same amount of fermentable OM(FOM) but characterized by different levels of ruminally degradable N (RDN). The first group primarily provided energy for the ruminal microbes (12.5 g of RDN/kg of FOM), whereas the second provided greater N (33.3 g of RDN/kg of FOM). These 2 groups were fed to the bulls in different combinations with the aim of creating 3 levels of imbalance (0, 20, and 40 g/ kg of DM) between energy andN supplies in the rumen. Imbalance was measured by the variation of the degradable protein balance (OEB value in the Dutch system) of the diet between the 2 meals each a day. Diurnal variations in ruminal NH3-N concentrations and plasma urea concentrations were greatly influenced by the feeding patterns of the diet. Introduction of imbalance affected neither microbial N flow at the duodenum (P = 0.97) nor efficiency of growth (P = 0.54). The feeding patterns of the diet had no negative impact on NDF degradation in the rumen (P = 0.33). Nitrogen retention was not affected by imbalance (P = 0.74) and reached 49.7, 52.0, and 51.3 g/d, respectively for 0, 20, and 40 g of OEB/kg of DM imbalance. It seems that introduction of an imbalance between energy and N supplies for the ruminal microbes by altering the feeding pattern of the same diet does not negatively influence the microbial activity in the rumen norNretention of the animal. Nitrogen recycling in the rumen plays a major role in regulating the amount of ruminally available N and allows a continuous synchronization of N and energyyielding substrates for the microorganisms in the rumen. Therefore, imbalance between dietary energy and N created over a 24-h interval was not detrimental to rumen microbial growth for the animal as long as the level of imbalance did not exceed 40 g of OEB/kg of DM. Thus, these feeding patterns of the diet can be used under practical feeding conditions with minimal impact on the performance of ruminant animals for meat production. [less ▲]

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See detailEffect of various levels of imbalance between energy and nitrogen supplies in the rumen on nitrogen metabolism in growing double-muscled Belgian Blue bulls fed maize silage based diet.
Valkeners, Damien; Beckers, Yves ULg; Amant, Stéphanie et al

in Proceedings of the British Society of Animal Science annual conference2005, York, UK. 4th-6th April, 2005 (2005, April)

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