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See detailDramatic Irony in David Jones's The Tribune's Visitation
Pagnoulle, Christine ULg

in Maes-Jelinek, Hena; Michel-Michot, Paulette; Michel, Pierre (Eds.) Multiple Worlds Multiple Words, Essays in Honour of Irène Simon (1988)

This short piece of criticism brings out the various levels of perception at work in one of David Jones' 'Roman fragments', set on the night before the Crucifixion and focusing on an officer checking on ... [more ▼]

This short piece of criticism brings out the various levels of perception at work in one of David Jones' 'Roman fragments', set on the night before the Crucifixion and focusing on an officer checking on his section. [less ▲]

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See detailDRAMATIC OSTEONECROSIS OF THE JAW ASSOCIATED WITH ORAL BIPHOSPHONATES TREATMENT AFTER IMPLANT REMOVAL: A CASE REPORT
FERNANDEZ AYORA, Alberto ULg; HERION, Francine ULg; LAMBERT, France ULg et al

Poster (2013, October)

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with ... [more ▼]

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with intravenous bisphosphonates while the incidence associated with oral bisphosphonates is not significant. AIM This report documents a case of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after dental implant removal in an osteoporotic patient treated with alendronate and risedronate for 15 years. MATERIAL AND METHODS An 83-years-old patient with no significant systemic disease underwent implant removal in the first molar left hemimandible position in 2010 due to a peri-implantitis. The surgical procedure was uneventful thought preventive measures were no taken. In June 2011, the patient was referred to our department with a wide bone sequestration of the left mandibular body. A panoramic radiograph showed an increased bone marrow density with bone sequestration. Since then, the patient underwent several courses of antibiotics and conservative therapy, without relief of symptoms. RESULTS Since 2011, the patient has lost 13 teeth in the mandible and the osteonecrosis has disseminated to the entire jaw and the left mandible condyle. The patient has even lost the left hearing. Resective surgery under general anesthesia is not indicated due to the risk because of the age of the patient. CONCLUSION AND CLINICAL IMPLICATIONS Despite the low risk of BRONJ occurrence after implant surgery in oral N-BP users, the fate of dental implants in these patients remains uncertain. Therefore patients at risk must be given a full explanation of the potential risks of implant failure and BRONJ development. Osteonecrosis of the jaws in association with bisphosphonate therapy is a very serious condition with which all dentists should be familiar. Since the treatment of BRONJ is difficult, prevention is the main goal. When the osteonecrosis begins, it can be very painful to the patient, difficult to treat, and can lead to very deleterious sequelae. [less ▲]

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See detailDramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Ayora, A F; HERION, Francine ULg; ROMPEN, Eric ULg et al

in Journal of Clinical Periodontology (2015), 42

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these ... [more ▼]

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients. [less ▲]

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See detailDramatic reduction of postnatal growth restriction after optimizing nutrition in extremely preterm infants
SENTERRE, Thibault ULg; Rigo, J

in Intensive Care Medicine (2011), 37(S2), 397

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See detailDramatic reduction of postnatal growth restriction after optimizing nutrition in very low birth weight infants.
SENTERRE, Thibault ULg; Rigo, J

in Pediatric Research (2011), 70(S5), 71

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See detail“Dramatising the Verse or Versifying the Drama: Rita Dove’s The Darker Face of the Earth: A Verse Play.”
Bada, Valérie ULg

in Phillips, Kimberley L.; Pinson, Hermine D.; Lorenzo, Thomas (Eds.) et al Critical Voicings of Black Liberation. Resistance and Representations in the Americas (2003)

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See detailDrame et récit de l'événement : qu'arrive-t-il au lecteur ?
Servais, Christine ULg

in Brunner, Pascale; Elefante, Chiara; Stavroula, Katsiki (Eds.) et al Interpréter l'événement. Aspects linguistiques, discursifs et sociétaux (2014)

On analyse ici les manifestations discursives de la contradiction que constitue en soi, pour le discours médiatique, un événement, et ce en faisant porter l'interrogation sur le récepteur. Il s'agit de se ... [more ▼]

On analyse ici les manifestations discursives de la contradiction que constitue en soi, pour le discours médiatique, un événement, et ce en faisant porter l'interrogation sur le récepteur. Il s'agit de se demander comment le média relaie le choc que constitue l'événement en nouant ensemble deux affirmations : l'événement fait quelque chose au discours médiatique et celui-ci fait quelque chose au lecteur. Cette dimension performative du discours est soutenue par la déconstruction derridienne du signe linguistique et par la notion de "partage du sensible" de Jacques Rancière. [less ▲]

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See detailLe drame romantique
Dumortier, Jean-Louis ULg

Scientific conference (2007, March 01)

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See detailLes Draps de lit
Demoulin, Laurent ULg

E-print/Working paper (2013)

Les Draps de lit est une pièce de théâtre inédite de Jean-Philippe Toussaint, antérieure à La Salle de bain. Elle est ici éditée avec un apparat critique: variantes et notes critiques.

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See detailDraw Belgium: Between Past, Present and Future
Grandjean, Geoffrey ULg; Reuchamps, Min ULg; Flaba, Elodie ULg

Article for general public (2009)

On 4th December 2008, 234 students in political and social sciences of the Université de Liège, Belgium, were invited to “Draw Belgium” on a blank sheet of paper. No other guidelines were given, so total ... [more ▼]

On 4th December 2008, 234 students in political and social sciences of the Université de Liège, Belgium, were invited to “Draw Belgium” on a blank sheet of paper. No other guidelines were given, so total freedom was left to the students. In addition to this request, the young citizens were asked to fill in a 19-question questionnaire about their federal perceptions and preferences as well as some political and socio-demographic indicators. The analysis of the results does contain interesting material for discussion about memory process and about attitudes towards European integration [less ▲]

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See detailDrawing-up of pesticide selectivity lists to beneficial arthropods for IPM programmes in potato.
Hautier, L.; Jansen, J. P.; Schiffers, Bruno ULg et al

in Communications in agricultural and applied biological sciences (2004), 69(3), 171-182

In order to promote IPM programmes in potato, the toxicity of 19 fungicides, 4 herbicides and 11 insecticides commonly used in this crop in Belgium was assessed on three beneficial arthropods. These ... [more ▼]

In order to promote IPM programmes in potato, the toxicity of 19 fungicides, 4 herbicides and 11 insecticides commonly used in this crop in Belgium was assessed on three beneficial arthropods. These species were representative of the most important aphid specific natural enemies encountered in potatoes: a parasitic wasp--Aphidius rhopalosiphi (De Stefani-Perez) (Hym., Aphidiidae), a ladybird--Adalia bipunctata (L.) (Col., Coccinellidae) and a hoverfly--Episyrphus balteatus (Dipt., Syrphidae). In a first time, pesticides were tested on glass plates on A. rhopalosiphi adults and A. bipunctata and E. balteatus larvae. For each insect, products inducing corrected mortality (Mc) lower than 30% were directly classified in a positive list for harmless products (green list). The other compounds were further tested on plants and listed in toxicity classes according to mortalities induced during this extended laboratory test: harmless (Mc < 30%), slightly harmful (30% < Mc < 60%), moderately harmful (60% < Mc < 80%) and harmful (Mc > 80). A chemical determination of pesticides residues was also performed for each experiment in order to determine the exposure of beneficial arthropods to pesticide residues and to validate the application of chemicals on tested substrates. On the basis of the results of acute toxicity tests, the period of each pesticide use according to normal agricultural practices and the abundance and importance of the three different groups of aphid natural enemies at different periods of the year, four pesticides lists were built up. Each list corresponded to a different period of pesticides application: Period I--from seedling to beginning of June (based on A. rhopalosiphi tests), Period II--beginning to end of June (based on A. rhopalosiphi tests), Period III beginning to end of July (based on E. balteatus and A. bipunctata tests) and Period IV--August to harvest (no exposure of beneficials). Results showed that herbicides were not toxic to the three species and can be used according to normal agricultural practices without restrictions. All fungicides can also be used without restrictions at recommended rates. Only the mixture Metalaxyl-M + Fluazinam was slightly harmful to A. bipunctata but had no effects on A. rhopalosiphi and E. balteatus. Results were more contrasted for insecticides and none of them was totally selective for all the 3 beneficial arthropods. Therefore, they can only be used with restrictions at periods II and III, according to the beneficial species that need to be protected. [less ▲]

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See detailDrawn in by the unpredictable: reward uncertainty broadens the spotlight of incentive salience attribution
Robinson, Mike J.F.; Fischer, Adam M.; Anselme, Patrick ULg et al

Poster (2012, May 19)

The motivational value assigned to cues (CSs) associated with reward (UCS) is known as incentive salience, and is determined through the synergy of previous learning of the CS-UCS association (the sum of ... [more ▼]

The motivational value assigned to cues (CSs) associated with reward (UCS) is known as incentive salience, and is determined through the synergy of previous learning of the CS-UCS association (the sum of experiences an individual has with that cue-reward combination) and the mesolimbic state of the individual at the time of cue re-encounter. Typically, the amount of incentive salience attributed to a cue is believed to increase with the relative reliability that the cue predicts reward, where cues that consistently predict reward become powerful motivational magnets, eliciting approach and even consummatory behaviors (similar to those produced by the reward itself). In contrast, cues that predict reward with a lesser degree of certainty should theoretically be less attractive, and accrue lower levels of incentive salience. However, in some cases, cues that predict reward with maximal levels of uncertainty, such as in gambling, may generate higher levels of incentive salience attribution and become very attractive. In order to examine the impact of uncertainty, we used a Pavlovian conditioned approach task (autoshaping), where a bright noisy lever cue precedes delivery of a sucrose reward pellet. We have previously shown that a cue that predicts a reward only half the time (probability = 50%), but where the value of that reward can vary (1, 2 or 3 sucrose pellets), attracts more incentive value than a cue that systematically (probability = 100%) predicts a single sucrose reward pellet. Here we examined whether the increased incentive value attributed to uncertain cues was equally distributed across cues that were proximal (5 cm) or distal (20 cm) to the site of reward (magazine). Our results confirm that incentive value is greater for uncertain cues, and show that it is equally distributed across proximal and distal cues. In contrast, when the CS cue predicts the UCS reward with absolute certainty, incentive value is preferentially given to proximal cues, with distal cues being almost ignored. This suggests that reward uncertainty not only attributes more incentive value to cues, but that it may also act by recruiting a broader range of cues. However, since the learnt predictive value of the cue is low, this increase in incentive salience may be generated through greater mesolimbic activity driven by anticipation and/or stress of an unpredictable reward. In conclusion, reward uncertainty may transform a broad array of cues into powerful motivational magnets, which in turn could help explain what makes gambling so attractive. [less ▲]

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See detailDRC1 expression on normal and pathological lymphoid cells.
Antoine, Nadine ULg; Heinen, Ernst ULg; Marcoty, C. et al

in Advances in Experimental Medicine and Biology (1993), 329

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See detailDre-miR-2188 Targets Nrp2a and Mediates Proper Intersegmental Vessel Development in Zebrafish Embryos.
Soares, Ana R.; Reverendo, Marisa; Pereira, Patricia M. et al

in PLoS ONE (2012), 7(6), 39417

BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed ... [more ▼]

BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed for miRNA target prediction however, experimental validation is still essential for the correct identification of miRNA targets. We have recently predicted that Neuropilin2a (Nrp2a), a vascular endothelial growth factor receptor which is essential for normal developmental angiogenesis in zebrafish, is a dre-miR-2188 target. METHODOLOGY: Here we show that dre-miR-2188 targets the 3'-untranslated region (3'UTR) of Nrp2a mRNA and is implicated in proper intersegmental vessel development in vivo. Over expression of miR-2188 in zebrafish embryos down regulates Nrp2a expression and results in intersegmental vessel disruption, while its silencing increases Nrp2a expression and intersegmental vessel sprouting. An in vivo GFP sensor assay based on a fusion between the GFP coding region and the Nrp2a 3'UTR confirms that miR-2188 binds to the 3'UTR of Nrp2a and inhibits protein translation. CONCLUSIONS: We demonstrate that miR-2188 targets Nrp2a and affects intersegmental vessel development in zebrafish embryos. [less ▲]

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See detailDREAM 2012: DEVELOPMENT OF LAPAROSCOPIC SURGERY AT THE UNIVERSITY HOSPITAL OF KINSHASA, DRC
Nsadi Fwene, Berthier ULg; Veyi, D; Kazadi, J et al

in Acta Chirurgica Belgica (2012, May), 112(3), 8240

Objectives: The technical nature of laparoscopy, and the required specific laparoscopic tools and medical skills, may render this approach difficult in developing countries. We hypothesized that ... [more ▼]

Objectives: The technical nature of laparoscopy, and the required specific laparoscopic tools and medical skills, may render this approach difficult in developing countries. We hypothesized that laparoscopy may be developed in the Cliniques Universitaires de Kinshasa (CUK), and may be cost-effective. The final aim of this program is to bring the benefits of laparoscopy to the DRC population, by allowance of adequate training on the UNIKIN personnel, including anaesthetists, surgeons and nurses, who in the future will have to locally form the DRC medical and nursery students. Methods: With the financial support from Wallonie-Bruxelles International (WBI), a complete CUK team, including a surgeon (2 years training in Belgium), an anaesthetist and nurses, were trained in Belgium and then afterwards in DRC. The laparoscopic equipment was sent to Kinshasa, and three theoretical and practical missions of Belgian teams were organised. Results: Over a 2 year period, 116 laparoscopic procedure were performed, including 32 appendectomies, 41 cholecystectomies, 11 hernia repairs, 9 laparoscopy explorations for peritoneal carcinoma assessment and biopsy, 8 procedures for catheter of dialysis peritoneal, 5 gynecologics procedures, and 10 other miscellaneous procedures. Conclusions: A joined approach, taking into account on one hand the training of the skills locally trained to adapt itself to some difficulties, on the other hand institutions of scientific support and a real program and local will of development of this new procedure are the wages of development, accessibility and durability of such news approach in developing countries. All University and non-University team willing to join such a project are welcome. [less ▲]

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See detailDREAM 2020: Development of laparoscopic surgery and endoscopy in the university hospital of Kinshasa, DRC
Nsadi, Berthier; Veyi, D.; Kazadi, J. et al

in Acta Gastro-Enterologica Belgica (2011, March), 74(1), 14

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See detailDreaming: a neuroimaging view
Dang Vu, Thien Thanh ULg; Desseilles, Martin ULg; Albouy, Geneviève ULg et al

in Schweizer Archiv Fur Neurologie und Psychiatrie (2005), 156

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See detailDreaming: A Neuropsychological View
Schwartz, Sophie; Dang Vu, Thien Thanh ULg; Ponz, Aurelie et al

in Schweizer Archiv für Neurologie und Psychiatrie = Archives Suisses de Neurologie et de Psychiatrie = Archivio Svizzero di Neurologia e Psichiatria (2005), 156(8), 426-439

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