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See detailThe Effect of Clonidine Infusion on Distribution of Regional Cerebral Blood Flow in Volunteers
Bonhomme, Vincent ULg; Maquet, Pierre ULg; Phillips, Christophe ULg et al

in Anesthesia and Analgesia (2008), 106(3), 899-909

BACKGROUND: Through their action on the locus coeruleus, alpha2-adrenoceptor agonists induce rapidly reversible sedation while partially preserving cognitive brain functions. Our goal in this ... [more ▼]

BACKGROUND: Through their action on the locus coeruleus, alpha2-adrenoceptor agonists induce rapidly reversible sedation while partially preserving cognitive brain functions. Our goal in this observational study was to map brain regions whose activity is modified by clonidine infusion so as to better understand its loci of action, especially in relation to sedation. METHODS: Six ASA I-II right-handed volunteers were recruited. Electroencephalogram (EEG) was monitored continuously. After a baseline H2(15)O activation scan, clonidine infusion was started at a rate ranging from 6 to 10 microg x kg(-1) x h(-1). A sequence of 11 similar scans was then performed at 8 min intervals. Plasma clonidine concentration was measured. Using statistical parametric mapping, we sought linear correlations between normalized regional cerebral blood flow (rCBF), an indicator of regional brain activity, and plasma clonidine concentration or spindle EEG activity. RESULTS: Clonidine induced clinical sedation and EEG patterns (spindles) comparable to early stage nonrapid eye movement sleep. A significant negative linear correlation between clonidine concentration and rCBF or spindle activity was observed in the thalamus, prefrontal, orbital and parietal association cortex, posterior cingulate cortex, and precuneus. CONCLUSIONS: The EEG patterns and decreases in rCBF of specific brain regions observed during clonidine-induced sedation are similar to those of early stage nonrapid eye movement sleep. Patterns of deactivated brain regions are also comparable to those observed during general anesthesia or vegetative state, reinforcing the hypothesis that alterations in the activity of a common network occur during these modified conscious states. [less ▲]

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See detailEffect of Clonidine on Propofol and Remifentanil requirements using BIS score and the A-line ARX (AAI) index during laparoscopic gastric bypass in obese patients
Rosant, Séverine; Nkiko, Gédéon; Lauwick, Séverine ULg et al

in Acta Anaesthesiologica Belgica (2008, June 14), 59(3), 228

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See detailEffect of CO2 activation of carbon xerogels on the adsorption of methylene blue
Páez Martínez, Carlos ULg; Contreras, M. S.; Léonard, Angélique ULg et al

in Adsorption (2012), 18(3-4), 199-211

The effect of physical activation with CO2 of carbon xerogels, synthesized by pyrolysis of a resorcinolformaldehyde aqueous gel, on the adsorption capacities of Methylene Blue (MB) was studied. The ... [more ▼]

The effect of physical activation with CO2 of carbon xerogels, synthesized by pyrolysis of a resorcinolformaldehyde aqueous gel, on the adsorption capacities of Methylene Blue (MB) was studied. The activation with CO2 lead to carbon materials with micropore volumes ranging from 0.28 to 0.98 cm³/g -1 C. MB-adsorption isotherm studies showed that the increase of micropore volume and corresponding surface area led to: (i) a significant improvement in the capacity of MB-adsorption at monolayer coverage, from 212 to 714 mgg -1 C, and (ii) an increase of the binding energy related to Langmuir isotherm constant up to 45 times greater than those of commercial microporous activated carbons used as reference (NORIT R2030, CALGON BPL and CALGON NC35). It is proposed that the increase of the binding energy results from chemical cleaning of the O-groups onto carbon surface as a consequence of CO2-activation, increasing the π-π interaction between MB and graphene layers of the carbon xerogels. Finally, a series of batch kinetics were performed to investigate the effect of CO2-activation conditions on the mechanism of MB-adsorption. Experimental data were fitted using pseudo-first-order, pseudo-second-order and intraparticle diffusion kinetic models. From pseudo-second-order kinetic model, one observes an increase in the initial rate of MB-adsorption from 0.019 to 0.0565 min -1, by increasing the specific surface area from 630 to 2180 m²/g -1 C via CO2-activation. Depending on the activation degree of the carbons, two different mechanisms control the MB-adsorption rate: (i) at low activation degree, the intraparticle diffusion is the rate-limiting phenomenon, whereas (ii) at high activation degree, the reactions occurring at the solid/liquid interface are the rate-limiting steps. © 2012 Springer Science+Business Media, LLC. [less ▲]

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See detailEffect of CO2 concentration on suspended particle dynamics during a mesocosm bloom experiment (Peece II)
Engel, Anja; Bellerby, R.; Delille, Bruno ULg et al

Conference (2007, April)

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See detailEFFECT OF CO2 INJECTION IN THE COMBUSTION AIR ON THE PERFORMANCE OF A HOT WATER DOMESTIC FUEL OIL BOILER
Milovanovic, Nebojsa; Ngendakumana, Philippe ULg

Conference (2000, August)

In order to investigate the effect of CO2 addition in the combustion air of a yellow flame burner, tests have been performed during which different volume flow rates of CO2 have been injected. For all the ... [more ▼]

In order to investigate the effect of CO2 addition in the combustion air of a yellow flame burner, tests have been performed during which different volume flow rates of CO2 have been injected. For all the tests performed, the burner consumption and the oxygen mole fraction in the flue gas have been kept quite constant, say at about 240 kW and 1.8 % (on dry basis) respectively. For the interpretation of the flame radiation results, tests have also been performed with N2 injection. The results gathered (for CO2 and N2 addition up to 4.8 % and 7.4 % in volume respectively) show that the thermal efficiency and the CO emission of the boiler are not affected. For small amounts of CO2 or N2 volume flow rates, there is a slight decrease of the NOx emission and the flame radiation. If the quantity of the additive is increased above a critical value, the flame becomes unstable and one observes first a sudden increase of the NOx emission and the flame radiation and then a decrease. That sudden increase is explained by the change of the flame shape and geometry. [less ▲]

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See detailEffect of Cognitive Load on Working Memory Forgetting in Aging
Baumans, Christine ULg; Adam, Stéphane ULg; Seron, Xavier

in Experimental Psychology (2012), 22

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See detailThe Effect of Colic on Oxygen Extraction in Horses
Cambier, Carole ULg; Wierinckx, Maude ULg; Grulke, Sigrid ULg et al

in Veterinary Journal (2008), 175(1), 102-107

Blood oxygen transport and oxygen extraction were assessed in horses with colic. A gravity score (GS) ranging from 1 to 3 was attributed to each colic case with healthy horses used as controls. Jugular ... [more ▼]

Blood oxygen transport and oxygen extraction were assessed in horses with colic. A gravity score (GS) ranging from 1 to 3 was attributed to each colic case with healthy horses used as controls. Jugular venous and carotid arterial blood samples were collected and concentrations of 2,3-diphosphoglycerate, adenosine triphosphate, inorganic phosphate and chloride were determined. pH and partial pressures of carbon dioxide (PCO(2)), and oxygen (PO(2)) were also measured. Oxygen equilibrium curves (OEC) were constructed under standard conditions and oxygen extraction ratios calculated. Haemoglobin oxygen affinity measured under standard conditions (P50(std)) was unchanged in colic horses compared with healthy controls. Horses with the highest GS, i.e. 3 had lower blood pH values than healthy animals. Arterial and venous partial pressures of oxygen at 50% haemoglobin saturation (P50(a) and P50(v)) were significantly higher in horses suffering from colic (GS=3) than in healthy horses. The oxygen extraction ratio was also significantly increased in colic horses with a GS of 3. A rise in the oxygen extraction ratio detected in the most severely affected animals seemed to reflect the compensatory properties of the oxygen transport system where extraction of oxygen from the blood increases when systemic oxygen delivery decreases, as might be anticipated in horses with colic. [less ▲]

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See detailEffect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo controlled study
Bruyère, Olivier ULg; Zegels, Brigitte ULg; Leonori, Lorenzo et al

in Complementary Therapies in Medicine (2012), 20

Objective: Evaluation of the efficacy and safety of a food supplement made of collagen hydrolysate 1200 mg/day versus placebo during 6 months, in subjects with joint pain at the lower or upper limbs or at ... [more ▼]

Objective: Evaluation of the efficacy and safety of a food supplement made of collagen hydrolysate 1200 mg/day versus placebo during 6 months, in subjects with joint pain at the lower or upper limbs or at the lumbar spine. Design: Comparative double-blind randomized multicenter study in parallel groups. Setting: 200 patients of both genders of at least 50 years old with joint pain assessed as ≥30 mm on a visual analogical scale (VAS). Intervention: Collagen hydrolysate 1200 mg/day or placebo during 6 months. Main outcome measure: Comparison of the percentage of clinical responder between the active collagen hydrolysate group and the placebo group after 6 months of study. A responder subject was defined as a subject experiencing a clinically significant improvement (i.e. by 20% or more) in the most painful joint using the VAS score. All analyses were performed using an intent-totreat procedure. Results: At 6 months, the proportion of clinical responders to the treatment, according to VAS scores, was significantly higher in the collagen hydrolysate (CH) group 51.6%, compared to the placebo group 36.5% (p < 0.05). However, there was no significant difference between groups at 3 months (44.1% vs. 39.6%, p = 0.53). No significant difference in terms of security and tolerability was observed between the two groups. Conclusions: This study suggests that collagen hydrolysate 1200 mg/day could increase the number of clinical responders (i.e. improvement of at least 20% on the VAS) compared to placebo. More studies are needed to confirm the clinical interest of this food supplement. [less ▲]

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See detailEffect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo controlled study
Bruyère, Olivier ULg; Zegels, Brigitte ULg; LEONORI, Lorenzo ULg et al

in Osteoporosis International (2012, March), 23(Suppl. 2), 362-363

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See detailThe effect of collagenated space filling materials in sinus bone augmentation: a study in rabbits
LAMBERT, France ULg; Léonard, Angélique ULg; Drion, Pierre ULg et al

in Clinical Oral Implants Research (2013), 24(5),

Aim: The inclusion of biomaterial particles used for alveolar bone regeneration in a carrier or in binding agents such as collagen gel or fibers is of interest as a means to help with surgical handling ... [more ▼]

Aim: The inclusion of biomaterial particles used for alveolar bone regeneration in a carrier or in binding agents such as collagen gel or fibers is of interest as a means to help with surgical handling. However, the possible influence of collagen on bone tissue response to biomaterials is poorly studied. The objective of the present study was to investigate, in a sub-sinus bone augmentation model in rabbits, the effect of collagen at different stages of the osteogenesis process. Histologic, histomorphometric and volumetric analyses were performed. Materials and methods: Rabbits underwent a double sinus lift procedure using bovine hydroxyapatite (BHA), collagenated bovine hydroxyapatite (BHAColl), and prehydrated and collagenated porcine hydroxyapatite (PHAColl). Animals were sacrificed at 1 week, 5 weeks or 6 months. Samples were subjected to X-ray micro-tomography and histology. Qualitative analysis was performed on the non-decalcified sections and quantitative histomorphometric analyses were conducted using scanning electron microscopy (SEM). Volume variations of bone augmentations were calculated at different time points. Results: The three biomaterials allowed an optimal bone formation and were able to equally withstand sinusal reexpansion. A comparable percentage of new bone, as well as 3D volume stability, was found between the groups at each time point. However, the PHAColl resorption rate was significantly higher than the rates in other groups (P = 0.0003), with only 3.6% of the particles remaining at 6 months. At 1 week, both collagenated groups displayed the presence of inflammatory cells although BHA did not show any sign of inflammation. At 5 weeks and 6 months, the inflammatory process had disappeared completely in the BHAColl groups, whereas some inflammatory-like cells could still be observed around the remaining particles of PHAColl. Conclusions and clinical implications: Within the limitations of this study in rabbits, the findings showed the presence of inflammatory-like cells at the early stage of bone regeneration when collagenated xenogenic biomaterials were used compared to xenogenic granules alone. Nevertheless, similar bone formation occurred and comparable 3D volumes were found at 6 months in the different groups. [less ▲]

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See detailThe effect of common bovine respiratory diseases on tidal breathing flow-volume loops
Lekeux, Pierre ULg; Art, Tatiana ULg; Amory, Hélène ULg

in Veterinary Research Communications (1988), 12(6), 463-473

In order to better understand the bovine breathing pattern, tidal breathing flow-volume loops (TBFVL) were analyzed in 24 healthy cattle of different body weights (range: 37-660 kg) (Group A) and in 28 ... [more ▼]

In order to better understand the bovine breathing pattern, tidal breathing flow-volume loops (TBFVL) were analyzed in 24 healthy cattle of different body weights (range: 37-660 kg) (Group A) and in 28 cattle suffering from the common respiratory diseases: verminous bronchitis (Group B); shipping fever (Group C); acute respiratory distress syndrome (Group D); respiratory syncytial virus pneumonia (Group E); organophosphate poisoning (Group F); and necrotic laryngitis (Group G). Respiratory airflow and tidal volume were measured with a breathing mask-Fleisch pneumotachograph assembly. TBFVL were traced from these values using a computerized method. All the loop indices proposed by Amis and Kurpershoek (1986a) were calculated from 5 representative breathing cycles for each of the 52 animals. The TBFVL shapes and indices were relatively constant in most healthy cattle and were not correlated with the body size. When compared to normal values, animals with moderate respiratory syndromes (Groups B and C) had a more flattened shape to their TBFVL. On the other hand, in most cattle with severe respiratory pathologies (Groups D, F and G expiration tended to be biphasic with the peak expiratory flow (PEF) occurring significantly later than in healthy animals. Both PEF and peak inspiratory flow were increased in all the pathological conditions. The TBFVL indices were more frequently and more severely changed during expiration than during inspiration. [less ▲]

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See detailThe effect of communication skills training on residents' physiological arousal in a breaking bad news simulated task
Meunier, Julie; Merckaert, Isabelle; Libert, Yves et al

in Patient Education & Counseling (2013), 93(1), 40-47

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See detailEffect of concentration temperature on some bioactive compounds and antioxidant proprieties of date syrup
Abbès, Fatma; Besbes, Souhail; Bchir, Brahim ULg et al

in Food Science & Technology International (2013), 19

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See detailThe effect of concrete substrate quality towards evaluation of repair system using impact-echo method
Garbacz, Andrzej; Piotrowski, Tomasz; Kwasniewski, L. et al

in Szczesniak, W. E.; A. Zbiciak, A. (Eds.) Theoretical foundations of civil engineering (2009, September)

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See detailEffect of concrete substrate texture on the adhesion properties of PCC repair mortar
Courard, Luc ULg; Garbacz, A.; Schwall, D. et al

in Barroso de Aguiar, J.; Jalali, S.; Camoes, A. (Eds.) et al Polymers in Concrete (2006, April)

The study of adhesion of repair materials on concrete structures implies a good knowledge of the influence of concrete surface characteristics. A large research project has been realized with regards to ... [more ▼]

The study of adhesion of repair materials on concrete structures implies a good knowledge of the influence of concrete surface characteristics. A large research project has been realized with regards to the influence of concrete substrate strength and preparation technique efficiency. Three types of concretes and four types of surface preparation have been combined in order to obtain twelve different concrete slabs. They have been characterized according different destructive and non destructive techniques: Schmidt hammer, compressive strength, superficial cohesion (pull-off tests), Impact Echo measurements and cracking quantification (microscopical observations). Finally, a polymer cement concrete mortar has been applied and adhesion has been evaluated by means of pull-off and laboratory tensile tests. The relationships between parameters describing surface quality (roughness, cracking), adhesion strength and stress wave propagation have been analysed. [less ▲]

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See detailEffect of concrete surface treatment on adhesion in repair systems
Garbacz, A.; Gorka, M.; Courard, Luc ULg

in Magazine of Concrete Research (2005), 57(1), 49-60

Existing concrete surfaces need to be roughened to a profile necessary to achieve mechanical interlocking with any repair material. In this study, different surface treatments (e.g. grinding, sandblasting ... [more ▼]

Existing concrete surfaces need to be roughened to a profile necessary to achieve mechanical interlocking with any repair material. In this study, different surface treatments (e.g. grinding, sandblasting, shotblasting, hand- and mechanical milling) were performed and the quality of the preparation established on the basis of three main parameters: surface geometry, superficial concrete microcracking and adhesion. Surface geometry was characterised on the basis of the measurement of surface profile-profilometry-and the analysis of statistical and amplitude parameters calculated from the waviness (lower frequencies) and the roughness (higher frequencies) profiles of the surface. Investigations were also performed to assess the quality of the superficial zone of concrete and cracks were systematically observed in relation to surface treatment where both scanning electron microscopy and light microscopy were used for analysis. Finally, a repair mortar with or without bond coat, was applied to the concrete substrates in order to measure adhesion. Relationships clearly show the effect of roughness on adhesion in the case where no bond coat was used and also the influence of the power of the surface treatment on the waviness shape of the profile and the presence of microcracks in the near-surface layer related to failure type. [less ▲]

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See detailThe effect of continuous galvanizing thermal cycle on the microstructure and mechanical properties of two multiphase TRIP-assisted steels
Mertens, Anne ULg; Bellhouse, Erika M.; Fourmentin, Richard et al

Scientific conference (2005, June 28)

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