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See detailEffets fonctionnels respiratoires induits par l'inhalation de glycopyrrolate chez le cheval poussif en crise
Art, Tatiana ULg; de Moffarts, Brieuc; Van Erck, Emmanuelle et al

in Annales de Médecine Vétérinaire (2003), 147

Bronchoconstriction is one of the most constant clinical sign observed in heaves-affected horses in crisis. Cholinergic pathways are involved in the occurrence of this obstruction. Consequently ... [more ▼]

Bronchoconstriction is one of the most constant clinical sign observed in heaves-affected horses in crisis. Cholinergic pathways are involved in the occurrence of this obstruction. Consequently anticholinergic drugs are potentially able to improve the pulmonary function of horses in acute crisis. Among these, atropine and ipratropium bromide have been previously experimented and their beneficial effects reported. In the present work, glycopyrrolate, another synthetic anticholinergic molecule has been tested for bronchodilator efficiency in heaves-affected horses. An acute exacerbation of the illness was obtained by a natural challenge with hay and straw in 7 heaves-affected horses. The first day, the reversibility of the bronchospasm of these horses was controlled by intravenous administration of atropine. Then, pulmonary function tests including mechanics of breathing, ie measurement of pleural pressure changes and respiratory airflows, and arterial blond gases analysis, were performed before as well as 15 and 60 minutes alter inhalation of 1500 µg of glycopyrrolate (Robinul®). The crisis induced a dramatic increase of total pulmonary resistance and maximal pleural pressure changes as well as a decrease in dynamic lung compliance. These changes were significantly reversed 15 and 60 minutes after inhalation of glycopyrrolate. We did not observe any adverse effects similar to those classically observed with atropine. These results showed that glycopyrrolate is a very efficient bronchodilator that may be used by the practitioner to treat a heaves-affected horses in crisis [less ▲]

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See detailEffets fonctionnels respiratoires induits par l'inhalation de glycopyrrolate chez le cheval poussif en crise
Art, Tatiana ULg; De Moffarts, Brieuc; Van Erck, Emmanuelle et al

in Pratique Vétérinaire Equine (2003), 35(139), 23-29

An acute respiratory attack with bronchospasm is associated with excessive stimulation of the parasympathic nervous system. It may be reduced by administration of anticholinergic agents. Atropine and ... [more ▼]

An acute respiratory attack with bronchospasm is associated with excessive stimulation of the parasympathic nervous system. It may be reduced by administration of anticholinergic agents. Atropine and ipratropium bromide have been tested. This study is to evaluate the efficacy of the synthetic antimuscarinic compound glycopyrrolate as a bronchodilator in horses. Respiratory crisis was induced in seven allergic horses by exposure to natural allergens. Prior to the study, it was established that the attack could be stopped using intravenous atropine sulphate. Pulmonary function tests (ventilation and arterial blood gas analysis) were performed on the horses before and then after aerosol administration of 1500 µg of glycopyrrolate (Robinul®). The attack was characterised by an increase in total pulmonary resis¬tance and maximum pleural pressure variation and by decreased compliance. This study demonstrates that glycopyrrolate exhibits affects that are just as rapid and effective as intravenous atropine or aerosol administration of 1200 µg dry powder Ipratropium. In addi¬tion the treatment was well tolerated and no side-effects were observed in contrast to those seen with intravenous administration of atro¬pine. Therefore this drug has an important role to play among the therapeutics available to practitioners for acute respiratory attacks in horses [less ▲]

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See detailEffets fonctionnels respiratoires induits par l’inhalation du glycopyrrolate chez le cheval poussif en crise.
Art, Tatiana ULg; de Moffarts; Van Erck, Emmanuelle ULg et al

in Congrès de l'Association Vétérinaire Equine Française (AVEF) (2003)

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See detailEffets génomiques et non-génomiques de l'oestradiol lors de l'activation du comportement sexuel mâle
Seredynski, Aurore ULg

Doctoral thesis (2014)

Testosterone, via its estrogenic metabolites, is involved in the control of different behaviors such as social communication or reproduction. Estrogens act mainly at the genomic level via the activation ... [more ▼]

Testosterone, via its estrogenic metabolites, is involved in the control of different behaviors such as social communication or reproduction. Estrogens act mainly at the genomic level via the activation of nuclear receptors to regulate the transcription of target genes but also act at the non- genomic level via the activation of membrane receptors. The main question of my work was how these two types of actions of estrogens interact to control male sexual behavior. [less ▲]

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See detailEffets indésirables cutanés des antagonistes du TNFa
Nikkels, Arjen ULg; Choffray, Alexandre; Sabatiello, Murielle ULg

in Skin (2009), 12(6), 165-170

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See detailEffets indesirables cutanes des interferons
Paquet, Philippe ULg; Pierard-Franchimont, Claudine ULg; Arrese, J. E. et al

in Revue Médicale de Liège (2001), 56(10), 699-702

The alpha, beta and gamma recombinant interferons are indicated in a growing spectrum of therapeutic indications. Some unwanted side effects occur on the skin. The main clinical presentations include ... [more ▼]

The alpha, beta and gamma recombinant interferons are indicated in a growing spectrum of therapeutic indications. Some unwanted side effects occur on the skin. The main clinical presentations include vesiculo-bullous sometimes infiltrated dermatitis, vasculitis, necrosis, ulceration and alopecia. Exacerbation of dermatoses such as psoriasis is also possible. [less ▲]

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See detailEffets lumineux et météores dans l'atmosphère terrestre
Biémont, Emile ULg

Book published by Presses Universitaires de France (1997)

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See detailEffets métaboliques des contractions musculaires volontaires et évoquées électriquement. Etude comparative par spectroscopie au P31 en résonance magnétique nucléaire
Vanderthommen, Marc ULg; Gilles, Raymond ULg; Carlier, P. et al

in Simon, L.; Pélissier, J.; Hérisson, C. (Eds.) Actualités en rééducation fonctionelle et réadaptation (1993)

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See detailEffets métaboliques et hormonaux d'un spray nasal d'insuline chez le sujet normal
PAQUOT, Nicolas ULg; SCHEEN, André ULg; Lefèbvre, Pierre ULg

in Acta Clinica Belgica (1987, April), 42(5),

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See detailEffets microcirculatoires et cellulaires de l'endotoxine
D'Orio, Vincenzo ULg

in Réanimation (1990)

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See detailEffets néfastes du defaut d'observance hygiéno-diététique et médicamenteuse chez le patient diabétique
Paquot, Nicolas ULg

in Revue Médicale de Liège (2010), 65(5-6), 326-31

The treatment of diabetes mellitus is complex and involves lifestyle modification to optimize nutrition and physical activity as well as the addition of pharmacological therapy to provide needed ... [more ▼]

The treatment of diabetes mellitus is complex and involves lifestyle modification to optimize nutrition and physical activity as well as the addition of pharmacological therapy to provide needed physiological support for insulin deficiency or for insulin resistance. Adherence to medical recommendations has been found to be associated with improved glycaemic control through HbA1c reduction but also to result in improved outcomes and reduced costs of diabetes. Despite this potential benefit of pharmacological therapy, adherence to glucose-lowering treatments is poor, ranging from 36% to 85% adherence to oral medications. The most common factors affecting medication taking in diabetic patients include regimen complexity, dosing frequency greater than twice daily, cost, poor self-confidence, insufficient education about the use of the products, depression, and adverse effects or fear of them. Several barriers to medication taking have been suggested although well-controlled trials to confirm and resolve these barriers are limited yet. Further studies are needed to test specific interventions to improve medication taking in diabetes. [less ▲]

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See detailEffets perturbateurs endocriniens des pesticides organochlorés
Charlier, Corinne ULg; Plomteux, Guy ULg

in Acta Clinica Belgica. Supplementum (2002), (1), 2-7

Xenoestrogens such organochlorine pesticides are known to induce changes in reproductive development, function or behaviour in wildlife. Because these compounds are able to modify the estrogens metabolism ... [more ▼]

Xenoestrogens such organochlorine pesticides are known to induce changes in reproductive development, function or behaviour in wildlife. Because these compounds are able to modify the estrogens metabolism, or to compete with estradiol for binding to the estrogen receptor, it may be possible that these products affect the risk of developing impaired fertility, precocious puberty or some kinds of cancer in man. [less ▲]

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See detailEffets perturbateurs endocriniens des pesticides organochlorés
Charlier, Corinne ULg

in Acta Clinica Belgica (2001)

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See detailEffets physiologiques de différents types de stress chez le chien avant et après blocage de stress chez le chien avant et après blocage beta-adrénergique par le carzolol
Gabriel, Annick ULg; Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1989), 133

The purpose of this experiment was to study (1) some cardio-vascular and metabolic effects of two different stress and (2) the modifications of these stress responses induced by a preventive ... [more ▼]

The purpose of this experiment was to study (1) some cardio-vascular and metabolic effects of two different stress and (2) the modifications of these stress responses induced by a preventive administration of carazolol. Five healthy beagle dogs were used. Firstly, a pharmacological stress was induced by an intravenous (IV) administration of epinephrine tartrate (1 ug/kg). The (3 adrenergic blockade was realised by an administration of carazolol (10ug/kg, IV). The changes in heart rate (HR), haematocrit, glycemia and blood gases were studied (1) to assess the stress-induced adjustements, (2) to study the effect of a R-adrenergic blockade on quiet resting dogs and (3) to estimate the efficiency of this blockade on the stress responses. Secondly, the dogs performed a standardized treadmill exercise, in order to produce a physiological stress. The adjustements to exercise on the one hand and the changes in these adjustements induced by a preventive administration of carazolol (10 ug/kg, I.M.) on the other hand were measured by the recording of the HR before, during and after the exercise. Epinephrine tartrate induced significant changes of HR, haematocrit and glycemia. The Beta-blockade reduced significantly these changes (P < 0,01). The exercise-induced increase of HR was also significantly reduced by the (beta-blockade (P < 0,01). On the oher hand, this blockade has no effects on the resting measured parameters. This study suggests that Beta-blockade by the carazolol has no indesirable effects on resting dogs and that it prevents the cardio-vascular and metabolic effects of stress. [less ▲]

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See detailEffets potentiels du stress sur les performances de reproduction en élevage bovin
Hanzen, Christian ULg

in Annales de la Faculté de Médecine Vétérinaire de l'UNILU (2006), XVII(1), 26-31

Detailed reference viewed: 34 (8 ULg)