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See detailDR-CALUX((R)) screening of food samples: evaluation of the quantitative approach to measure dioxin, furans and dioxin-like PCBs
Scippo, Marie-Louise ULg; Eppe, Gauthier ULg; De Pauw, Edwin ULg et al

in Talanta (2004), 63(5), 1193-1202

European legislation laid down maximum tolerable levels of dioxin in feed and food as well as analytical method requirements. In order to face with large monitoring programs, it was foreseen in the EU ... [more ▼]

European legislation laid down maximum tolerable levels of dioxin in feed and food as well as analytical method requirements. In order to face with large monitoring programs, it was foreseen in the EU strategy to integrate screening methods, using either a qualitative (screening) approach, or a quantitative approach. In this study, dioxin results obtained using the Dioxin Responsive Chemical-Activated LUciferase gene eXpression (DR-CALUX(R)) cell-based assay (quantitative approach), were compared with gas chromatography-high resolution mass spectrometry (GC-HRMS) analyses data. Instead of using World Health Organization-toxic equivalent factor (WHO-TEF), the comparison was based on the assessment of relative effective potencies (REPs) for each congener of the 17 toxic 2,3,7,8-polychlorodibenzo-p-dioxins/furans (PCDD/Fs) and 12 dioxin-like polychlorobiphenyls (DL-PCBs). According to published data, DR-CALUX(R)-REP evaluated here appear similar to WHO-TEF for PCDD/Fs while lower values were observed for DL-PCBs. We analyzed two "home made" contaminated fat samples, displaying both the same WHO-toxic equivalent quantities (WHO-TEQ) concentration (12 pg WHO-TEQ g(-1)). They were spiked with either a low or a high amount of DL-PCBs. In both cases, the DR-CALUX(R) measured concentration (picogram 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) eq. g(-1)) corresponded to the PCDD/Fs WHO-TEQ concentration only. A good agreement was nevertheless found between the DR-CALUX(R) measurements and the recalculated DR-CALUX(R)-TEQ contents (using DR-CALUX(R)-REP instead of WHO-TEF), demonstrating that the observed response was due, in both cases, to the addition of the responses of the standards added to the fat. By contrast, in real contaminated samples (feed or cod liver samples), DR-CALUX(R) measured concentrations were similar to WHO-TEQ GC-HRMS measured concentrations. But, depending on the PCDD/Fs and DL-PCBs congener content, the DR-CALUX(R) measured concentrations were either lower or higher than calculated DR-CALUX(R)-TEQ contents, demonstrating that possible co-extracted contaminants contributed to the CALUX response. Owing to these divergences, the quantitative determination of dioxin-like content in food and feed using CALUX as screening method is questionable, except for samples displaying constant congener patterns, in which cases, correction factors could be applied. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailDraagmoederschap en afstammingsbanden - een Belgisch ipr-perspectief
Wautelet, Patrick ULg

in Rutten, Susan; Saarloos, Kees (Eds.) Van afstamming tot nationaliteit. Opstellen aangeboden aan professor mr. G. R. de Groot ter gelegenheid van zijn 25-jarig ambtsjubileum als hoogleraar rechtsvergelijing en internationaal privaatrecht aan de Universiteit Maastricht (2013)

In this paper, I offer some considerations on the impact of cross-border surrogacy agreements from Belgian (private international law) perspective. The paper starts from a case decide in 2013 by a first ... [more ▼]

In this paper, I offer some considerations on the impact of cross-border surrogacy agreements from Belgian (private international law) perspective. The paper starts from a case decide in 2013 by a first instance court in Belgium to discuss the main difficulties arising out of cross-border surrogacy agreements. The paper offers a critical review of the way courts in Belgium have dealt with cross-border surrogacy cases. [less ▲]

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See detailA draft for a typology of urban observatories
Farah, Jihad ULg

Conference (2011, September)

Urban observatories represent today a global phenomenon. In the last decades, public actors, universities and civil society actors have established hundreds of urban observatories all around the world ... [more ▼]

Urban observatories represent today a global phenomenon. In the last decades, public actors, universities and civil society actors have established hundreds of urban observatories all around the world. Some of these observatories actively contribute to the analysis of urban dynamics and affect urban policy making. However, urban observatories are still understudied; the scientific literature on urban observatories is rare and culturally fragmented. This article seeks to contribute to the development of a body of knowledge on urban observatories, by proposing a typology of urban observatories that stress the potential impacts and contributions of four different archetypes on urban and territorial planning and management. [less ▲]

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See detailDraft Matrimonial Property Regulations : Some Observations on the Rules of Jurisdiction
Wautelet, Patrick ULg

Conference (2011, October 17)

In this presentation I offer some observations on selected rules of jurisdiction which have been included in the twin Draft EU Regulations on Matrimonial Assets (Proposals for Regulations on jurisdiction ... [more ▼]

In this presentation I offer some observations on selected rules of jurisdiction which have been included in the twin Draft EU Regulations on Matrimonial Assets (Proposals for Regulations on jurisdiction, applicable law and the recognition and enforcement of decisions in matters of matrimonial property regimes and regarding the property consequences of registered partnerships). More specifically, the focus is on Article 5 of the Draft Regulations and on the rules relating to parallel proceedings (art. 9, 12 and 13). [less ▲]

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See detailDraft overview paper on trend analysis in groundwater summarizing the main results of TREND2 in relation to the new Groundwater Directive
Broers, H.P.; Visser, A.; Bierkens, M.F.P. et al

Report (2008)

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See detailThe Draft Regulations on Matrimonial Property : a Critical Appraisal
Wautelet, Patrick ULg

Conference (2011, September)

This short presentation gives an overview of the twin Draft Regulations proposed by the EU Commission in March 2011 to create a European wide private international law framework for matrimonial assets.

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See detailDrafting International Commercial Agreements - a Primer
Wautelet, Patrick ULg

Learning material (2011)

This presentation is used as a basis for a course on drafting international commercial agreements. It is complemented by two cases studies. The course is mainly addressed to non lawyers and is hence ... [more ▼]

This presentation is used as a basis for a course on drafting international commercial agreements. It is complemented by two cases studies. The course is mainly addressed to non lawyers and is hence rather practice than law oriented. The course is not linked to one jurisdiction or one type of contract in particular, but attempts to address general issues related to international commercial agreements. [less ▲]

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See detailDrag Minimisation Using Adaptive Aeroelastic Structures
Hodigere-Siddaramaiah, Vijaya; Cooper, Jonathan E; Vio, Gareth A. et al

in Proceedings of the 48th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference (2007, April)

This paper describes the latest developments in a research program investigating the development of “adaptive internal structures” to enable adaptive aeroelastic control of aerospace structures. Through ... [more ▼]

This paper describes the latest developments in a research program investigating the development of “adaptive internal structures” to enable adaptive aeroelastic control of aerospace structures. Through controlled changes of the second moment of area, orientation or position of the spars, it is possible to control the bending and torsional stiffness characteristics of aircraft wings or tail surfaces. The aeroelastic behaviour can then be controlled as desired. A number of different adaptive internal structure concepts (rotating, moving and split spars) are compared here using a simple rectangular wing structure in order to determine which are the most effective for achieving minimum drag at different points in a representative flight envelope. A genetic algorithm approach is employed to determine the optimal spar orientation for rotating spars concept. It is shown that it is feasible to adjust the structure and trim characteristics of such wing structures in order to achieve minimum drag at all conditions. [less ▲]

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See detailDrag reduction by dilute polymer additives
Terrapon, Vincent ULg

Scientific conference (2003, February)

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See detailThe dragonflies monitoring scheme in Southern Belgium: a tool to assist wetlands management.
Goffart, Philippe; Baguette; Dufrêne, Marc ULg

in Conserving and managing Wetlands for Invertebrates (1991)

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See detailDrains verticaux et matériel associé
Van der Stede, Véronique ULg

in Lebeau, Marc; Suleiman, Antoine (Eds.) Tell Beydar, Five Seasons of Excavations (1995-1999), A Preliminary Report (2003)

 Cet article décrit en détail les dispositifs de drainage équipant le complexe palatial et le temple A de Tell Beydar. Il y est également question des aménagements fixes qui y sont associés et qui ... [more ▼]

 Cet article décrit en détail les dispositifs de drainage équipant le complexe palatial et le temple A de Tell Beydar. Il y est également question des aménagements fixes qui y sont associés et qui doivent vraisemblablement être interprétés comme des toilettes à siège. [less ▲]

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See detailDramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis
Bebrone, Carine ULg; Anne, C.; De Vriendt, K. et al

in Journal of Biological Chemistry (2005), 280(31), 28195-28202

Among class B beta-lactamases, the subclass B2 CphA enzyme is characterized by a unique specificity profile. CphA efficiently hydrolyzes only carbapenems. In this work, we generated site-directed mutants ... [more ▼]

Among class B beta-lactamases, the subclass B2 CphA enzyme is characterized by a unique specificity profile. CphA efficiently hydrolyzes only carbapenems. In this work, we generated site-directed mutants that possess a strongly broadened activity spectrum when compared with the WT CphA. Strikingly, the N116H/N220G double mutant exhibits a substrate profile close to that observed for the broad spectrum subclass B1 enzymes. The double mutant is significantly activated by the binding of a second zinc ion under conditions where the WT enzyme is non-competitively inhibited by the same ion. [less ▲]

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See detailDramatic improvement of severe dilated cardiomyopathy in an acromegalic patient after treatment with octreotide and trans-sphenoidal surgery.
Legrand, Victor ULg; Beckers, Albert ULg; Pham, V. T. et al

in European Heart Journal (1994), 15(9), 1286-9

Severe congestive heart failure developed in an acromegalic patient, and was successfully treated with octreotide followed by trans-sphenoidal surgery. Clinical, hormonal echocardiographic and ... [more ▼]

Severe congestive heart failure developed in an acromegalic patient, and was successfully treated with octreotide followed by trans-sphenoidal surgery. Clinical, hormonal echocardiographic and haemodynamic findings as well as histological heart examination before and after treatment revealed that over-production of growth hormone may induce the myocardial cell degeneration responsible for mechanical heart dysfunction. In addition, this unique example demonstrates the reversibility of myocardial damage following octreotide and trans-sphenoidal surgery, leading to significant improvement in cardiac function with minimal diastolic dysfunction and moderate interstitial fibrosis. [less ▲]

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See detailDramatic Irony in David Jones's The Tribune's Visitation
Pagnoulle, Christine ULg

in Maes-Jelinek, Hena; Michel-Michot, Paulette; Michel, Pierre (Eds.) Multiple Worlds Multiple Words, Essays in Honour of Irène Simon (1988)

This short piece of criticism brings out the various levels of perception at work in one of David Jones' 'Roman fragments', set on the night before the Crucifixion and focusing on an officer checking on ... [more ▼]

This short piece of criticism brings out the various levels of perception at work in one of David Jones' 'Roman fragments', set on the night before the Crucifixion and focusing on an officer checking on his section. [less ▲]

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See detailDRAMATIC OSTEONECROSIS OF THE JAW ASSOCIATED WITH ORAL BIPHOSPHONATES TREATMENT AFTER IMPLANT REMOVAL: A CASE REPORT
FERNANDEZ AYORA, Alberto ULg; HERION, Francine ULg; LAMBERT, France ULg et al

Poster (2013, October)

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with ... [more ▼]

BACKGROUND Osteoporosis affects millions of elderly patients. Bisphosphonates represent first-line therapy. Osteonecrosis of the jaws in patients treated with bisphosphonates is mostly associated with intravenous bisphosphonates while the incidence associated with oral bisphosphonates is not significant. AIM This report documents a case of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after dental implant removal in an osteoporotic patient treated with alendronate and risedronate for 15 years. MATERIAL AND METHODS An 83-years-old patient with no significant systemic disease underwent implant removal in the first molar left hemimandible position in 2010 due to a peri-implantitis. The surgical procedure was uneventful thought preventive measures were no taken. In June 2011, the patient was referred to our department with a wide bone sequestration of the left mandibular body. A panoramic radiograph showed an increased bone marrow density with bone sequestration. Since then, the patient underwent several courses of antibiotics and conservative therapy, without relief of symptoms. RESULTS Since 2011, the patient has lost 13 teeth in the mandible and the osteonecrosis has disseminated to the entire jaw and the left mandible condyle. The patient has even lost the left hearing. Resective surgery under general anesthesia is not indicated due to the risk because of the age of the patient. CONCLUSION AND CLINICAL IMPLICATIONS Despite the low risk of BRONJ occurrence after implant surgery in oral N-BP users, the fate of dental implants in these patients remains uncertain. Therefore patients at risk must be given a full explanation of the potential risks of implant failure and BRONJ development. Osteonecrosis of the jaws in association with bisphosphonate therapy is a very serious condition with which all dentists should be familiar. Since the treatment of BRONJ is difficult, prevention is the main goal. When the osteonecrosis begins, it can be very painful to the patient, difficult to treat, and can lead to very deleterious sequelae. [less ▲]

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See detailDramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Ayora, A F; HERION, Francine ULg; ROMPEN, Eric ULg et al

in Journal of Clinical Periodontology (2015), 42

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these ... [more ▼]

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients. [less ▲]

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See detailDramatic reduction of postnatal growth restriction after optimizing nutrition in extremely preterm infants
SENTERRE, Thibault ULg; Rigo, J

in Intensive Care Medicine (2011), 37(S2), 397

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See detailDramatic reduction of postnatal growth restriction after optimizing nutrition in very low birth weight infants.
SENTERRE, Thibault ULg; Rigo, J

in Pediatric Research (2011), 70(S5), 71

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See detail“Dramatising the Verse or Versifying the Drama: Rita Dove’s The Darker Face of the Earth: A Verse Play.”
Bada, Valérie ULg

in Phillips, Kimberley L.; Pinson, Hermine D.; Lorenzo, Thomas (Eds.) et al Critical Voicings of Black Liberation. Resistance and Representations in the Americas (2003)

Detailed reference viewed: 8 (1 ULg)