L’Étrenne des Lumières. Trente ans de prédictions dans l’Almanach de LiègeDroixhe, Daniel ![]() in Lüsebrink, H.-J.; Mix, Y.-G.; Mollier, J.-Y. (Eds.) et al Les lectures du peuple en Europe et dans les Amériques (XVIIe au XXe siècle) (2003) Detailed reference viewed: 47 (1 ULg) Ets-dependent regulation of target gene expression during megakaryopoiesisJackers, Pascale ; ; et alin Journal of Biological Chemistry (2004), 279(50), 52183-52190 Megakaryopoiesis is the process by which hematopoietic stem cells in the bone marrow differentiate into mature megakaryocytes. The expression of megakaryocytic genes during megakaryopoiesis is controlled ... [more ▼] Megakaryopoiesis is the process by which hematopoietic stem cells in the bone marrow differentiate into mature megakaryocytes. The expression of megakaryocytic genes during megakaryopoiesis is controlled by specific transcription factors. Fli-1 and GATA-1 transcription factors are required for development of megakaryocytes and promoter analysis has defined in vitro functional binding sites for these factors in several megakaryocytic genes, including GPIIb, GPIX, and C-MPL. Herein, we utilize chromatin immunoprecipitation to examine the presence of Ets-1, Fli-1, and GATA-1 on these promoters in vivo. Fli-1 and Ets-1 occupy the promoters of GPIIb, GPIX, and C-MPL genes in both Meg-01 and CMK11-5 cells. Whereas GPIIb is expressed in both Meg-01 and CMK11-5 cells, GPIX and C-MPL are only expressed in the more differentiated CMK11-5 cells. Thus, in vivo occupancy by an Ets factor is not sufficient to promote transcription of some megakaryocytic genes. GATA-1 and Fli-1 are both expressed in CMK11-5 cells and co-occupy the GPIX and C-MPL promoters. Transcription of all three megakaryocytic genes is correlated with the presence of acetylated histone H3 and phosphorylated RNA polymerase II on their promoters. We also show that exogenous expression of GATA-1 in Meg-01 cells leads to the expression of endogenous c-mpl and gpIX mRNA. Whereas GPIIb, GPIX, and C-MPL are direct target genes for Fli-1, both Fli-1 and GATA-1 are required for formation of an active transcriptional complex on the C-MPL and GPIX promoters in vivo. In contrast, GPIIb expression appears to be independent of GATA-1 in Meg-01 cells. [less ▲] Detailed reference viewed: 54 (35 ULg) Etude du processus constitutif de la parentification au sein de la famille dynamique : l’apport szondien.Haxhe, Stéphanie ![]() Scientific conference (2011, December 03) Detailed reference viewed: 9 (0 ULg) Etude historique et archéologique du château de Franchimont à TheuxHoffsummer, Patrick ![]() Master's dissertation (1980) Detailed reference viewed: 8 (0 ULg) L’étude ACCOMPLISH : remise en question des choix médicamenteux chez les patients hypertendus systoliques à haut risque cardio-vasculaireKrzesinski, Jean-Marie ; Scheen, André ![]() in Revue Médicale de Liège (2009), 64(2), 103-108 Arterial hypertension is an important cardiovascular risk factor. The benefit drawn from decreasing and normalizing the blood pressure level is indisputable. The ACCOMPLISH study performed in patients ... [more ▼] Arterial hypertension is an important cardiovascular risk factor. The benefit drawn from decreasing and normalizing the blood pressure level is indisputable. The ACCOMPLISH study performed in patients older than 65 with systolic hypertension and a high cardiovascular risk pointed out the interest of well choosing the antihypertensive combination to reduce this risk beyond the decrease of blood pressure. The association of benazepril (an angiotensin converting enzyme inhibitor or ACEI) and amlodipine (a calcium antagonist) has shown significant early cardiovascular protection in such patients as compared to the classic association including the same ACEI and hydrochlorothiazide, in spite of the same target blood pressure reached. This important finding does not contest the interest of a well controlled blood pressure in hypertension, but probably will modify our first antihypertensive combination choice in the future in patients with such cardiovascular profile. [less ▲] Detailed reference viewed: 215 (20 ULg) Etude analytique de la flore et de la végétation du Parc National de la Ruvubu, Burundi.; ; et al in International Journal of Biological and Chemical Sciences (2010), 4(4), 834-856 Detailed reference viewed: 9 (2 ULg) Etude analytique des trois trousses de cystatine C et impact sur les formules basées sur la cystatine pour l'estimation du DFG.Cavalier, Etienne ; ; et alin Néphrologie & Thérapeutique (2008, November), 4(6), 399-400 Detailed reference viewed: 42 (8 ULg) Etude approchée des roulements rigides à billes chargé radialement, dans le cas des grandes vitessesDebongnie, Jean-François ![]() Report (1992) The classical rolling bearing theory lies on the assumption that the rotational speed is low. The simplest correction for high speeds consists in adding only the centrifugal load. But even in this frame ... [more ▼] The classical rolling bearing theory lies on the assumption that the rotational speed is low. The simplest correction for high speeds consists in adding only the centrifugal load. But even in this frame, the problem is by far complicated. However, in the case of a radial load, it is possible to develop an approximated formulation which easily leads to realistic results. This elementary theory may be used as a basis of comparison for more evolved theories, which may be useful. [less ▲] Detailed reference viewed: 44 (4 ULg) Etude archéologique et dendrochornologique de la maison du Pléban à DinantHoffsummer, Patrick ; in Archaeologia mediaevalis (1992), 15 The "Maison du Pléban" in Dinant is a timber framed house with old parts of the end of the 15th century, modified and enlarged during the 16th and 18th centuries. Detailed reference viewed: 10 (0 ULg) Etude archéologique et dendrochronologique des charpentes de l'église de la Sainte-Vierge à Chaussée-Notre-Dame (Soignies); Hoffsummer, Patrick ; Maggi, Christophe et alin Bulletin de la Commission royale des Monuments, Sites et Fouilles (2011), 23 Thanks to archaeological observations on roofs of this church during the restauration and also with the help of dendrochronology, new data were obtained on the evolution of this interesting gothic church ... [more ▼] Thanks to archaeological observations on roofs of this church during the restauration and also with the help of dendrochronology, new data were obtained on the evolution of this interesting gothic church of the region Hainaut in Belgium [less ▲] Detailed reference viewed: 28 (7 ULg) Etude archéologique et historique du château de Franchimont à TheuxHoffsummer, Patrick ![]() Book published by Université de Liège (1982) Detailed reference viewed: 30 (1 ULg) Etude astérosismologique du système KPD 1930+2752Van Grootel, Valérie ![]() Master of advanced studies dissertation (2005) Detailed reference viewed: 9 (0 ULg)![]() Etude au microscope électronique à balayage de cellules normales ou cancéreuses fixées et déshydratées par différentes méthodesHeinen, Ernst ; in Bulletin de l'Académie Royale de Médecine de Belgique (1974), 161 Detailed reference viewed: 18 (1 ULg)![]() Etude au microscope electronique a balayage du palais secondaire en formation chez le rat.; Heinen, Ernst ![]() in Bulletin de l'Association des Anatomistes (1977), 61(172), 61-70 Normal fetuses 14 to 17 days old were obtained from female Wistar rats. The palates have been studied, after dissection, by scanning electron microscopy. Palatal closure is achieved, in the median and ... [more ▼] Normal fetuses 14 to 17 days old were obtained from female Wistar rats. The palates have been studied, after dissection, by scanning electron microscopy. Palatal closure is achieved, in the median and posterior region, by the elevation of the lateral palatine processus from a ventro-medial to a horizontal position; immediately after the horizontalization, they adhere to each other. Rostrally naso-palatine canal closure takes place later; it results from an epithelial and mesenchymal outgrowth under the nasal septum. The mutual adhesivity of the free edges of the lateral processes is noticeable. The pattern of the fusion surface has been considered, elements such as exfoliated cells, filopodes and microvilli are present. Their contribution to the adherence phenomenon is discussed. [less ▲] Detailed reference viewed: 18 (2 ULg)![]() Etude au microscope electronique a balayage et a transmission de l'epithelium amniotique chez la ratte en fin de gestation.; Heinen, Ernst ; Papart, Luc ![]() in Bulletin de l'Association des Anatomistes (1977), 61(172), 81-91 The pattern of the amniotic epithelium during the eight last days of pregnancy is described with the aid of scanning and transmission microscopy. A flattening of the cells appears near the term. Their ... [more ▼] The pattern of the amniotic epithelium during the eight last days of pregnancy is described with the aid of scanning and transmission microscopy. A flattening of the cells appears near the term. Their area becomes progressively greater increasing their contact surface with the amniotic fluid. Simultaneaously, their microvilli become more numerous. During the 20th, the 21st and the 22nd days of pregnancy, we observed cytoplasmic processes emanating from the base of the cell interrupting the basal membrane and entering the underlying connective substance. No evidence of cell degeneration was seen. [less ▲] Detailed reference viewed: 40 (4 ULg) Etude Belge HelpED :Effet de la revalidation érectile par iPDE 5 sur l’évolution psychosociale de l’homme pour dysfonction érectileAndrianne, Robert ; ; et alin Belgian Journal of sexual health (2011) Detailed reference viewed: 25 (5 ULg) Etude bibliographique concernant les phases de type martensite et Widmanstatten dans les alliages de Titane (Ti6Al4V)Paydas, Hakan ; Lecomte-Beckers, Jacqueline ![]() Report (2011) Detailed reference viewed: 20 (5 ULg) Etude biochimique et immunocytochimique des protéines argyrophiles des organisateurs nucléolaires (protéines-AgNORs).; Thiry, Marc ; Poster (1995) Detailed reference viewed: 1 (0 ULg) |
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