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See detailEarly detection of university students in potential difficulty : a case study
Hoffait, Anne-Sophie ULg; Schyns, Michael ULg

Conference (2014, November)

Rate of success in the first year at University in Belgium is very low regarding other foreign universities. The University of Liege, as other Universities, has already taken different initiatives. But by ... [more ▼]

Rate of success in the first year at University in Belgium is very low regarding other foreign universities. The University of Liege, as other Universities, has already taken different initiatives. But by early identifying students who have a high probability to face difficulties if nothing is done, the Universities might develop adapted methods to attack the problem with more emphasis where it is more needed and when it is still possible. Thus we want to develop a decision tool able to identify these students to help them. For that, we consider three standard datamining methods: logistic regression, artificial neural networks and decision trees and focus on early detection, i.e. before starting at the University. Then, we suggest to adapt these three methods as well as the classification framework in order to increase the probability of correct identification of the students. In our approach, we do not restrict the classification to two extreme classes, e.g. failure or success, but we create subcategories for different levels of confidence: high risk of failure, risk of failure, expected success or high probability of success. The algorithms are modified accordingly and to give more weight to the class that really matters. Note that this approach remains valid for any other classification problems for which the focus is on some extreme classes; e.g. fraud detection, credit default... Finally, simulations are conducted to measure the performances of the three methods, with and without the suggested adaptation. We check if the factors of success/failure we can identify are similar to those reported in the literature. We also make a ``what-if sensitivity analysis''. The goal is to measure in more depth the impact of some factors and the impact of some solutions, e.g., a complementary training or a reorientation. [less ▲]

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See detailEarly development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location, number of flares, and smoking but not by NOD2/CARD15 genotype
Louis, Edouard ULg; Michel, V.; Hugot, J. P. et al

in Gut (2003), 52(4), 552-557

Background: Crohn's disease is a heterogeneous entity. Disease behaviour, characterised as structuring, penetrating, or non-stricturing non-penetrating, is a clinically important phenotype as it is ... [more ▼]

Background: Crohn's disease is a heterogeneous entity. Disease behaviour, characterised as structuring, penetrating, or non-stricturing non-penetrating, is a clinically important phenotype as it is associated with complications and need for surgery. It has recently been showed that the behaviour of Crohn's disease changes over the course of the disease. Aim: To assess the association between rapid development of a penetrating or stricturing pattern of Crohn's disease and demographic and clinical characteristics as well as NOD2/CARD15 genotype. Patients and methods: A total of 163 patients with a firm diagnosis of Crohn's disease and who had non-penetrating non-stricturing disease at diagnosis were studied. Various demographic and clinical characteristics as well as anitsaccharomyces cerevisiae antibody status and NOD2/CARD15 genotype were documented in these patients. These characteristics were compared in subgroups of patients according to evolution of disease behaviour five years after diagnosis. Results: Five years after diagnosis there were 110 (67.5%) patients with non-structuring non-penetrating disease, 18 (11%) with stricturing disease, and 35 (21.5%) with penetrating disease. In multivariate analysis, only disease location and number of flares per year were significantly discriminant between the three subgroups (p=0.0009 and 0.0001, respectively). Ileal location of the disease was associated with a stricturing pattern while a high number of flares was associated with a penetrating pattern. Active smoking was also associated with a penetrating pattern compared with a non-stricturing non-penetrating pattern only. Conclusions: Early development of stricturing or penetrating behaviour in Crohn's disease is influenced by disease location, clinical activity of the disease, and smoking habit, but not by NOD2/CARD15 genotype. [less ▲]

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See detailEarly development of the chondrocranium in Chrysichtys auratus (Pisces, Siluriformes, Claroteidae)
Vandewalle, Pierre ULg; Chikou, Antoine; Lalèyé, Philippe et al

in Journal of Fish Biology (1999), 55

The inception and development of the cartilaginous cephalis skeleton of Chrysichthys auratus is described from hatching to about 18 days post-hatching. At hatching, no skeletal structure is present. Not ... [more ▼]

The inception and development of the cartilaginous cephalis skeleton of Chrysichthys auratus is described from hatching to about 18 days post-hatching. At hatching, no skeletal structure is present. Not until day 3 do clearly delimited cranial primordia become apparent. As in many siluriforms, the neurocranium is platybasic from the start, the suspensorium constitutes, with Meckel’s cartilage and the hyoid bar, a single cartilaginous element, and the junction between the front and rear of the neurocranium is complete on day 4. By day 8 the quadratomandibular joint has formed and the tectum posterius has appeared. Cartilage reduction first affects the trabecular bars, then, markedly, the visceral arches. By day 18 the braincase floor has almost disappeared. [less ▲]

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See detailearly development of the condrocranium in Chrysichtys auratus (Siluriformes, Claroteidae)
Vandewalle, Pierre ULg; Chikou, Antoine; Lalèyé, Philippe et al

Poster (1998)

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See detailEarly development of the head skeleton in Brycon moorei (Pisces, Ostariophysi, Characidae)
Vandewalle, Pierre ULg; Germeau, G.; Besancenet, P. et al

in Journal of Fish Biology (2005), 66(4), 996-1024

At hatching (15 h post fertilization), Brycon moorei possesses no skeletal structure. Thereafter, development is very rapid. The first oral teeth appear no later than 3 It post-hatching, but they remain ... [more ▼]

At hatching (15 h post fertilization), Brycon moorei possesses no skeletal structure. Thereafter, development is very rapid. The first oral teeth appear no later than 3 It post-hatching, but they remain covered with epithelium until c. 45 h. At 7 h, the trabecular bars and part of the cartilaginous visceral arches are visible and at 15 It, the dentaries and premaxillaries are present. At 25 h, i.e. the onset of piscivory and cannibalism (the yolk sac is only fully resorbed after 36 h), the oral teeth are fully developed, the first pharyngeal teeth are formed, and some head movements already appear synchronized, but the mouth cavity is not completely isolated from the neurocranium by bony structures. Thereafter, no new buccal or pharyngeal bony structure is visible until 45 h, when the maxilla and opercula appear, along with a new type of cannibalistic behaviour. Cartilage resorptions also start at 45 It, but with no concomitant replacement by formation of calcified structures. Later, development gradually becomes similar to that of many previously studied teleosts. The developmental pattern of B. moorei is thus extremely rapid in comparison with other teleosts, i.e. it prioritizes feeding structures that permit the expression of piscivory at a very early age. The uniqueness of this pattern is discussed in relation to ecological constraints on early feeding and fast growth. (c) 2005 The Fisheries Society of the British Isles. [less ▲]

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See detailEarly developmental actions of endocrine disruptors on the hypothalamus, hippocampus, and cerebral cortex.
Parent, Anne-Simone ULg; Naveau, Elise; GERARD, Arlette ULg et al

in Journal of Toxicology and Environmental Health. Part B, Critical Reviews (2011), 14(5-7), 328-45

Sex steroids and thyroid hormones play a key role in the development of the central nervous system. The critical role of these hormonal systems may explain the sensitivity of the hypothalamus, the ... [more ▼]

Sex steroids and thyroid hormones play a key role in the development of the central nervous system. The critical role of these hormonal systems may explain the sensitivity of the hypothalamus, the cerebral cortex, and the hippocampus to endocrine-disrupting chemicals (EDC). This review examines the evidence for endocrine disruption of glial-neuronal functions in the hypothalamus, hippocampus, and cerebral cortex. Focus was placed on two well-studied EDC, the insecticide dichlorodiphenyltrichloroethane (DDT) and polychlorinated biphenyls (PCB). DDT is involved in neuroendocrine disruption of the reproductive axis, whereas polychlorinated biphenyls (PCB) interact with both the thyroid hormone- and sex steroid-dependent systems and disturb the neuroendocrine control of reproduction and development of hippocampus and cortex. These results highlight the impact of EDC on the developing nervous system and the need for more research in this area. [less ▲]

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See detailAn Early Devonian flora, including Cooksonia from the Paraná Basin (Brazil)
Gerrienne, Philippe ULg; Bergamaschi, S.; Pereira, E. et al

in Review of Palaeobotany and Palynology (2001), 116

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See detailThe Early Devonian plants from the Ancenis Basin (Armorican Massif, France): one century later...
Strullu-Derrien, Marie-Christine; Gerrienne, Philippe ULg

Conference (2008)

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See detailEarly diagnosis of myocardial infarction by measuring the tissue isoform of CK-MB in serum
Chapelle, Jean-Paul ULg

in Annales de Biologie Clinique (1993), 51

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See detailEarly diagnosis of myocardial infarction using a new automated immunoassay for serum myoglobin
Chapelle, Jean-Paul ULg; El Allaf, Dia ULg

in European Heart Journal Supplements : Journal of the European Society of Cardiology (1993), 14(Abs. suppl.), 32

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See detailEarly Earth, extremophiles and Exobiology
Javaux, Emmanuelle ULg

Conference (2005)

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See detailEarly effect of hyaluronic acid intra-articular injections on serum and urine biomarkers in patients with knee osteoarthritis: An open-label observational prospective study.
Conrozier, T.; Balblanc, J. C.; Richette, P. et al

in Journal of Orthopaedic Research (2011)

The aim of the study was to investigate the effect of hyaluronic acid (HA) intra articular injections (IA) on osteoarthritis (OA) biomarkers in patients with knee OA. Prospective open label study. Fifty ... [more ▼]

The aim of the study was to investigate the effect of hyaluronic acid (HA) intra articular injections (IA) on osteoarthritis (OA) biomarkers in patients with knee OA. Prospective open label study. Fifty-one patients with unilateral symptomatic K-OA received IA injections of 2mL of HA on days (D) 1, 7, 14 and were followed 3 months. At D-15 patients were examined and X-rays performed, to exclude patients with bilateral K-OA, or those with more than three symptomatic OA joints. From 15 days (D-15) before the first injection to D90 concomitant therapies were unchanged. Walking pain (WP) on VAS was obtained at each visit. Urine (U) and serum (S) samples were obtained at D-15, D1, D30, and D90. S-C2C, S-Cartilage oligomeric matrix protein, S-HA, S-CS 846 epitope, S-type II collagen propeptide, and U-type II collagen C telopeptide (U-CTX II/creatinin) were assayed. Predictive factors of response were analyzed using logistic regression. Correlations between variables were obtained using Spearman test. Forty-five patients were analyzed. Between D-15 and D1 there was no difference for any biomarkers At D1, WP (SD) was correlated with U-CTX II/creat (p = 0.006). Between D1 and D90: U-CTX II/creat decreased significantly. After adjustment for confounding variables there was a significant correlation between clinical response and U-CTX II/creat variation. U-CTX II and S-HA at baseline were independently predictive of clinical response. This study showed that 90 days after HA IA injections, U-CTX II levels significantly decrease compared to baseline, suggesting a slowdown of type II collagen degradation. (c) 2011 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res. [less ▲]

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See detailEarly effect of strontium ranelate on clinical vertebral fractures in women with postmenopausal osteoporosis
Meunier, P. J.; Marquis, P.; Lemmel, E. M. et al

in BONE (2003), 32(S7), 222

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See detailThe early eukaryote fossil record
Javaux, Emmanuelle ULg

in Jékely, Gáspár (Ed.) Evolution of the Eukaryotic Endomembrane System and Cytoskeleton (2006)

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See detailEarly eukaryotes in Paleoproterozoic and Mesoproterozoic oceans
Javaux, Emmanuelle ULg; Marshall, C.; Xiao, S. et al

Poster (2004)

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See detailEarly eukaryotic diversification
Javaux, Emmanuelle ULg; knoll, A. H.; Walter, M.

Conference (2002)

Detailed reference viewed: 12 (0 ULg)