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See detailDysthyroidies et dyslipidemies.
Deschampheleire, M.; Luyckx, Françoise ULg; Scheen, André ULg

in Revue Médicale de Liège (1999), 54(9), 746-50

While overt thyroid disturbances, characterized by symptoms and/or clinical signs with abnormal serum levels of thyroid hormones, are generally associated with perturbations in the lipid profile, the ... [more ▼]

While overt thyroid disturbances, characterized by symptoms and/or clinical signs with abnormal serum levels of thyroid hormones, are generally associated with perturbations in the lipid profile, the situation is less clear as far as subclinical thyroid disturbances, defined by isolated abnormalities of thyroid stimulating hormone (TSH) levels, are concerned. In severe hyperthyroidism, a decrease of total cholesterol, LDL cholesterol and apoprotein B concentrations is generally observed. These biological parameters are normalized when appropriate antithyroid treatment is given. In profound hypothyroidism, on the contrary, elevated levels of total and LDL cholesterol levels are observed, which decrease after hormonal replacement. In both cases, the changes in serum levels of HDL cholesterol, triglycerides and lipoprotein (a) are less systematic, both before and after treatment. Lipid abnormalities associated with subclinical thyroid disturbances remain controversial. However, two recent meta-analyses have shown higher LDL cholesterol levels in presence of subclinical hypothyroidism and a significant reduction of such lipid abnormality after administration of thyroxine. Furthermore, they demonstrated a higher prevalence of subclinical hypothyroidism in a population with hypercholesterolaemia when compared to a population with normal cholesterol levels. Finally, a significant reduction in both total and LDL cholesterol concentrations has been reported after administration of thyroxine in a small group of hypercholesterolaemic patients with basal TSH levels in the upper range of normal values. In view of the results of the literature, strategies are proposed to help the clinician in the management of patients with overt or subclinical thyroid disturbances, associated with dyslipidaemia. [less ▲]

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See detailDysthyroïdies iatrogènes
Maiga, Ibrahima ULg; VALDES SOCIN, Hernan Gonzalo ULg; DELWAIDE, Jean ULg et al

in Abstract book - Annales d'Endocrinologie : 31ème Congrès de la Société Française d'Endocrinologie, Lyon 5-8 novembre 2014 (2014, October)

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See detailDystocies équines: Données descriptives et approche de la gestion des soins intensifs
Deleuze, Stefan ULg; de la Rebière de Pouyade, Geoffroy ULg; Sandersen, Charlotte ULg et al

Conference (2011, December 02)

La fréquence de fourbures rencontrées après une dystocie semble faible par rapport à la littérature. L’ajout d’héparines fractionnées aux traitements habituels de la métrite du post-partum (ocytocine ... [more ▼]

La fréquence de fourbures rencontrées après une dystocie semble faible par rapport à la littérature. L’ajout d’héparines fractionnées aux traitements habituels de la métrite du post-partum (ocytocine, lavage utérins, antibiotiques et anti-inflammatoires) semble intéressant pour réduire le risque de fourbure. [less ▲]

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See detailDystonies cervicales
DELVAUX, Valérie ULg; GONCE, Michel ULg

Article for general public (2002)

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See detailDystopies de fin du monde. Une poétique littéraire du désastre
Stienon, Valérie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2012)

Le récit d’anticipation négatif développe une réflexion sur la cohésion d’une société à travers l’histoire d’une communauté humaine dont l’organisation collective et les bases sociales sont fragilisées ... [more ▼]

Le récit d’anticipation négatif développe une réflexion sur la cohésion d’une société à travers l’histoire d’une communauté humaine dont l’organisation collective et les bases sociales sont fragilisées, voire détruites. Ce genre littéraire ne s’apparente pas seulement au roman cataclysmique ou aux multiples scénarios de la guerre future. Il se rapproche aussi des ambitions de la politique-fiction et des procédés de l’anticipation scientifique. Entre 1830, date des premières anti-utopies constituées en récit, et 1950, moment de convergence de ces récits avec la science-fiction naissante, la production dystopique francophone s’avère riche, complexe et encore peu étudiée. D’Albert Robida à René Barjavel, nombreux sont pourtant les récits à (re-)considérer sous cet angle. [less ▲]

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See detailDΑΡΡΩΝ AND ΔΑΙΜΟΝ: A New Inscription from Mylasa
Carbon, Jan-Mathieu ULg

in Epigraphica Anatolica (2005)

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Peer Reviewed
See detail“E andè drétt u n s va invéll”: Percorsi di Raffaello Baldini
Benzoni, Pietro ULg

in Studi novecenteschi (2000), XXVII(59), 7-57

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See detailE lectron–phonon couplings at C60 interfaces: a case study by two- color, infrared–visible sum–frequency generation spectroscopy
Caudano, Yves; Silien, C.; Humbert, Christophe et al

in Journal of Electron Spectroscopy & Related Phenomena (2003), 129

We demonstrate the ability of doubly resonant sum–frequency generation (DR-SFG) to investigate electron–phonon couplings at C60 –metal interfaces. Due to its coupling to electronic transitions, the ... [more ▼]

We demonstrate the ability of doubly resonant sum–frequency generation (DR-SFG) to investigate electron–phonon couplings at C60 –metal interfaces. Due to its coupling to electronic transitions, the totally symmetric Ag(2) vibration of C60 exhibits a huge enhancement of its nonlinear response for sum–frequency energies above the molecular electronic gap. We attribute this resonance to the coupling of the pentagonal pinch mode with the tiu lowest unoccupied molecular orbital (LUMO) of C60. [less ▲]

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Peer Reviewed
See detailÉ possibile selezionare dei bovini meno sensibili alle malattie respiratorie ?
Lekeux, Pierre ULg; Bureau, Fabrice ULg; Jacqmot, Olivier

in Proceedinds: 4° Congresso Nazionale Multisala SIVAR (2002)

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See detail(E)-2'-Deoxy-2'-(Fluoromethylene)cytidine potentiates radioresponse of two human solid tumor xenografts.
Sun, L-Q; Li, Y-X; Guillou, L et al

in Proceedings of the American Association for Cancer Research (1998)

Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC), a novel inhibitor of ribonucleotide reducÃase, were evaluated on nude mice bearing s.c. human C33-A cervix ... [more ▼]

Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC), a novel inhibitor of ribonucleotide reducÃase, were evaluated on nude mice bearing s.c. human C33-A cervix cancer and I -H7 MG glioblastoma xenografts. FMdC given once daily has a dosedependent antitumor effect. The maximum tolerated dose in the mice was reached with 10 daily i.p. administrations of 10 mg/kg over 12 days. In the case of radiotherapy (RT) alone (10 fractions over 12 days), the radiation dose required to produce local tumor control in 50% of the treated C33-A xenografts was 51.0 Gy. When combined with FMdC, the radiation dose required to produce local tumor control was reduced to 41.4 and 38.2 Gy, at respective doses of 5 and 10 mg/kg given i.p. l h before each irradiation. The corresponding enhancement ratios (ERs) were 1.2 and 1.3, respec tively. In U-87 MG xenografts, when 5-20 mg/kg FMdC combined with 30 or 40 Gy of RT, the combination treatment produced a significantly increased growth delay as compared with RT alone (P £0.002). The ERs of 5, 10, and 20 mg/kg FMdC at a dose of 30 Gy were 2.0, 1.4, and 1.8, respectively. At the 40-Gy level, ERs of 10 and 20 mg/kg FMdC were 1.4 and 1.7. When FMdC was combined with 50 Gy of RT, an increased long-term remission rate of 80-88.9% was observed, as compared with 25% for RT alone (P <0.05). FMdC produced moderate myelosuppression in the mice bearing cervix cancer, whereas leukocytosis occurred in the mice bearing glioblastoma at a low dose. Slightly increased skin toxicity (only with U-87 MG tumor) was observed, as compared with RT alone. In conclusion, FMdC is a potent cytotoxic agent and able to modify the radiation response of C33-A and U-87 MG xenografts. [less ▲]

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See detaile-Agora : a portal to support the use of e-learning at the University of Liege
Lecomte, Béatrice ULg

Scientific conference (2006)

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See detailE-b-farnesene synergizes the influence of an insecticide to improve control of cabbage aphids in China
Cui, L.L; Dong, J.; Francis, Frédéric ULg et al

in Crop Protection (2012)

Extensive use of pesticides to control insect pests can have negative effects on the environment, natural enemies and food safety. The aphid alarm pheromone, E-b-farnesene (Ebf), appears to hold strong ... [more ▼]

Extensive use of pesticides to control insect pests can have negative effects on the environment, natural enemies and food safety. The aphid alarm pheromone, E-b-farnesene (Ebf), appears to hold strong potential for controlling a wide variety of aphid pests. To understand the control potential of Ebf, we used field experiments in a factorial design to test its influence and that of the insecticide imidacloprid on populations of aphids Lipaphis erysimi (Kaltenbach) and Myzus persicae (Sulzer) on Chinese cabbage, Brassica rapa pekinensis (Brassicales: Brassicaceae). Our results showed imidacloprid treatment alone can significantly decrease aphid populations, and that combining insecticide with Ebf further reduced numbers of apterous aphids at distances of 5 m from pheromone emitters in two years of our experiments. Our results demonstrate that imidacloprid can be effective in reducing the abundance of aphids in Chinese cabbage fields, but the degree of control can be even stronger in the presence of Ebf. [less ▲]

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See detailE-books : what interest(s) in 2012 for life sciences' library users at the University of Liège, Belgium?
Vandenput, Sandrina ULg; Detroz, Pascal ULg; Brouwir, Christine ULg et al

in Journal of the European Association for Health Information and Libraries (2012), 8(4), 9-11

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Peer Reviewed
See detailE-cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells
Nawrocki-Raby, B.; Gilles, Christine ULg; Polette, M. et al

in American Journal of Pathology (2003), 163(2), 653-661

The disorganization of E-cadherin/catenin complexes and the overexpression of matrix metalloproteinases (MMPs) are frequently involved in the capacity of epithelial cells to acquire an invasive phenotype ... [more ▼]

The disorganization of E-cadherin/catenin complexes and the overexpression of matrix metalloproteinases (MMPs) are frequently involved in the capacity of epithelial cells to acquire an invasive phenotype. The functional link between F-cadherin and MMPs was studied by transfecting invasive bronchial BZR tumor cells with human E-cadherin cDNA. Using different in vitro (cell dispersion, modified Boyden chamber) and in vivo assays (human airway epithelial xenograft), we showed that E-cadherin-positive clones displayed a decrease of invasive abilities. As shown by immunoprecipitation, the re-expressed E-cadherin was able to sequestrate one part of free cytoplasmic beta-catenin in BZR cells. The decrease of beta-catenin transcriptional activity in E-cadherin-transfected clones was demonstrated using the TOP-FLASH reporter construct. Finally, we observed a decrease of MMP-1, MMP-3, MMP-9, and MT1-MMP, both at the mRNA and at the protein levels, in E-cadherin-positive clones whereas no changes in MMP-2, TIMP-1, or TIMP-2 were observed when compared with control clones. Moreover, zymography analysis revealed a loss of MMP-2 activation ability in E-cadherin-positive clones treated with the concanavalin A lectin. These data demonstrate a direct role of E-cadherin/catenin complex organization in the regulation of MMPs and suggest an implication of this regulation in the expression of an invasive phenotype by bronchial tumor cells. [less ▲]

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See detailThe E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression
Bonnomet, A.; Polette, M.; Strumane, K. et al

in Oncogene (2008), 27(26), 3692-9

In this study, we examined the role of the E-cadherin-repressed gene human Nanos1 (hNanos1) in tumor invasion process. First, our in vivo study revealed that hNanos1 mRNAs were overexpressed in invasive ... [more ▼]

In this study, we examined the role of the E-cadherin-repressed gene human Nanos1 (hNanos1) in tumor invasion process. First, our in vivo study revealed that hNanos1 mRNAs were overexpressed in invasive lung carcinomas. Moreover, hNanos1 was co-localized with MT1-MMP (membrane type 1-matrix metalloproteinase) in E-cadherin-negative invasive lung tumor clusters. Using an inducible Tet-on system, we showed that induction of hNanos1 expression in DLD1 cells increased their migratory and invasive abilities in a three-dimensional migration and in a modified Boyden chamber assay. Accordingly, we demonstrated that hNanos1 upregulated MT1-MMP expression at the mRNA and protein levels. Inversely, using an RNA interference strategy to inhibit hNanos1 expression in invasive Hs578T, BT549 and BZR cancer cells, we observed a downregulation of MT1-MMP mRNA and protein and concomitantly a decrease of the invasive capacities of tumor cells in a modified Boyden chamber assay. Taken together, our results demonstrate that hNanos1, by regulating MT1-MMP expression, plays an important role in the acquisition of invasive properties by epithelial tumor cells. [less ▲]

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See detailL'e-commerce (commerce électronique): les bonnes pratiques pour réussir
Jacob, Damien ULg

Book published by Edipro (2012)

Ce livre s’adresse plus particulièrement aux commerçants «indépendants», débutants ou confirmés. Il concerne autant ceux qui envisagent de lancer une nouvelle activité commerciale en ligne que ceux qui ... [more ▼]

Ce livre s’adresse plus particulièrement aux commerçants «indépendants», débutants ou confirmés. Il concerne autant ceux qui envisagent de lancer une nouvelle activité commerciale en ligne que ceux qui souhaiteraient positionner leur business actuel également en ligne. Il fait le point sur le "commerce connecté" et sur les bonnes pratiques de mise en place d’une stratégie en la matière. Si la volonté affichée est d’inciter à entreprendre une activité commerciale en ligne, il serait trompeur de faire croire qu’il s’agit d’un eldorado. Cet ouvrage se veut donc réaliste en livrant l’état de l’art, avec des recommandations concrètes pour maximaliser les chances de réussite et éviter les écueils les plus fréquemment observés. [less ▲]

Detailed reference viewed: 231 (27 ULg)
See detaile-demos, the e-courses showcases at ULg
Lecomte, Béatrice ULg

Scientific conference (2008)

The e-demos interface was designed to serve the purpose of showcasing online courses and activities designed by the Ulg's academic personnel. e-demos allows you to browse its interface using instructional ... [more ▼]

The e-demos interface was designed to serve the purpose of showcasing online courses and activities designed by the Ulg's academic personnel. e-demos allows you to browse its interface using instructional or administrative criteria. Each e-demo contains: - a guided tour, - teachers interviews, - a detailed showcase : learning events, assessment, tutoring,… "e-demos" is one of our ways to help our community to share their experience and expertise and not to let "newcomers" alone. It gives visitor explanation of the choice that were made in terms of instructional design. [less ▲]

Detailed reference viewed: 21 (5 ULg)