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See detailEarly ontogenesis od sensitization to the behavioral effects of cocaine in rats.
Tirelli, Ezio ULg; Adam, Eric; Ferrara, Maurizio

in Behavioural Pharmacology (1994), 5

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See detailAn early origin of plastids within the cyanobacterial divergence is suggested by evolutionary trees based on complete 16S rRNA sequences
Nelissen, Bart; Van De Peer, Yves; Wilmotte, Annick ULg et al

in Molecular Biology and Evolution (1995), 12

It is generally accepted that the plastids arose from a cyanobacterial ancestor, but the exact phylogenetic relationships between cyanobacteria and plastids are still controversial. Most studies based on ... [more ▼]

It is generally accepted that the plastids arose from a cyanobacterial ancestor, but the exact phylogenetic relationships between cyanobacteria and plastids are still controversial. Most studies based on partial 16S rRNA sequences suggested a relatively late origin of plastids within the cyanobacterial divergence. In order to clarify the exact relationship and divergence order of cyanobacteria and plastids, we studied their phylogeny on the basis of nearly complete 16S rRNA gene sequences. The data set comprised 15 strains of cyanobacteria from different morphological groups, 1 prochlorophyte, and plastids belonging to 8 species of plants and 12 species of diverse algae. This set included three cyanobacterial sequences determined in this study. This is the most comprehensive set of complete cyanobacterial and plastidial 16S rRNA sequences used so far. Phylogenetic trees were constructed using neighbor joining and maximum parsimony, and the reliability of the tree topologies was tested by different methods. Our results suggest an early origin of plastids within the cyanobacterial divergence, preceded only by the divergence of two cyanobacterial genera, Gloeobacter and Pseudanabaena. [less ▲]

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See detailThe early Paleozoic carbon cycle
Godderis, Y.; François, Louis ULg; Veizer, J.

in Earth And Planetary Science Letters (2001), 190(3-4), 181-196

A review of O, C, Sr and S isotope trends for the entire Phanerozoic shows that the present-day values of isotope signals are similar to those at the Proterozoic termination. The sharp rise in Sr-87/Sr-86 ... [more ▼]

A review of O, C, Sr and S isotope trends for the entire Phanerozoic shows that the present-day values of isotope signals are similar to those at the Proterozoic termination. The sharp rise in Sr-87/Sr-86 since similar to 65 Ma has been attributed to an uplift and subsequent metamorphism and erosion associated with the Himalayas and Tibet. This orogenic evolution has been postulated to have influenced the global organic and inorganic carbon cycles and climate as well. A similar large-scale orogeny, the Pan-African event, also dominated the Neoproterozoic (Vendian) times, and the similarity of modern and Neoproterozoic isotope values for seawater may therefore have had a comparable tectonic cause. In this contribution, we present the results of a numerical model of the coupled C-alkalinity-S-Sr cycles suggesting that the early Paleozoic (from early Cambrian to late Devonian) evolution of Sr, O, C and S seawater isotope signals could have been the consequence of progressive oxidation of a large reduced carbon reservoir exhumed during the Pan-African orogeny. The delta O-18 measured in brachiopod shells is used as a forcing of the model, postulating that any change in the oxygen isotopic composition of seawater is the result of a disequilibrium in the organic carbon subcycle through the coupling of the oxygen isotopic and carbon cycles. The calculated delta C-13, Sr-87/Sr-86 and delta S-34 are in good agreement with the data, as is the reasonable calculated history for atmospheric pCO(2) and its relation to global climate. (C) 2001 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailEarly postmenopausal women have high prevalence of inadequate serum vitamin D levels. Results of a European study
Bruyère, Olivier ULg; Malaise, Olivier; Neuprez, Audrey ULg et al

in Osteoporosis International (2006, March), 17(Suppl.1), 85-86

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See detailEarly prediction of electric power system blackouts by temporal machine learning
Geurts, Pierre ULg; Wehenkel, Louis ULg

in Proceedings of ICML-AAAI 98 Workshop on "Predicting the future: AI approaches to time series analysis" (1998)

This paper discusses the application of machine learning to the design of power system blackout prediction criteria, using a large database of random power system scenarios generated by Monte-Carlo ... [more ▼]

This paper discusses the application of machine learning to the design of power system blackout prediction criteria, using a large database of random power system scenarios generated by Monte-Carlo simulation. Each scenario is described by temporal variables and sequences of events describing the dynamics of the system as it might be observed from real-time measurements. The aime is to exploit the data base in order to derive as simple as possible rules which would allow to detect an incipient blackout early enough to prevent or mitigate it. We propose a novel "temporal tree induction" algorithm in order to exploit temporal attributes and reach a compromise between the degree of anticipation and selectivity of detection rules. Tests are carried out on a a data base related to voltage collapse of an existing large scale power system. [less ▲]

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See detailEarly prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen.
Beguin, Yves ULg; Loo, Martine; R'Zik, Samir ULg et al

in Blood (1993), 82(7), 2010-6

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known ... [more ▼]

Recombinant human erythropoietin (rHuEpo) has been shown to be effective in correcting the anemia of chronic renal failure, but the dose needed may be variable. The reason for this variation is not known, but several factors could be involved, such as iron deficiency, inflammation, aluminum intoxication, hyperparathyroidism, blood losses, or marrow dysfunction. Treatment with rHuEpo was given intravenously thrice weekly after hemodialysis to 64 consecutive unselected patients with the anemia of chronic renal failure. The starting dose was 50 U/kg/dose, which was increased to 75 and 100 U/kg/dose if no response was observed after 1 and 2 months of treatment. After a minimum follow-up of 6 months, response was evaluated as early (hematocrit [Hct] > or = 30% before 3 months) or late (Hct > or = 30% after 3 months) response, or failure (target Hct not attained). We examined the value of various laboratory parameters (baseline values and early changes) as predictors of response to rHuEpo. The best prediction by pretreatment parameters only was obtained with baseline serum transferrin receptor (TfR) (< or > or = 3,500 ng/mL) and fibrinogen (< or > or = 4 g/L): 100% response rate when both parameters were low, versus only 29% when they were both high, and versus 67% when one was low and the other high. When the 2-week TfR increment was greater than 20%, the response rate was 96%. When TfR increment was less than 20%, the response rate was 100% when baseline TfR and fibrinogen were low, 12% when fibrinogen was elevated, and 62% when fibrinogen was low but baseline TfR high. The predictive value of baseline TfR and fibrinogen and of the 2-week increment of TfR was confirmed by life table analysis and stepwise discriminant analysis. Major reasons for failure or late response were identified and included subclinical inflammation, iron deficiency, functional iron deficiency, marrow disorders, hemolysis, bleeding, and low Epo dose. We conclude that response to rHuEpo can be predicted early by pretreatment fibrinogen and TfR, together with early changes of TfR levels. These prognostic factors illustrate the importance of the early erythropoietic response, subclinical inflammation, and functional iron deficiency. Early recognition of a low probability of response in a given patient could help identify and correct specific causes of treatment failure to hasten clinical improvement and avoid prolonged ineffective use of an expensive medication. [less ▲]

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See detailEarly Prediction of Transient Voltage Sags caused by Rotor Swings
Weckesser, Tilman; Johannsson, Hjortur; Van Cutsem, Thierry ULg

in Proc. IEEE PES general meeting (in press)

The paper investigates various methods to predict voltage sags at load buses caused by large generator rotor swings and following a transient disturbance. Three different prediction methods are proposed ... [more ▼]

The paper investigates various methods to predict voltage sags at load buses caused by large generator rotor swings and following a transient disturbance. Three different prediction methods are proposed, which all use real-time measurements from PMUs. One of the methods uses a slightly extended version of the E-SIME method. The other two methods use measurements and process them by recursive least square estimation. It is shown that the prediction method employing E-SIME allows the earliest detection of a critical voltage sag with satisfactory accuracy. [less ▲]

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See detailEarly pregnancy detection in sheep. Secondary communication
Karen, Aly; Beckers, Jean-François ULg; Sulon, Joseph ULg et al

Poster (2005)

A szerzők a juhok vemhességének korai megállapítására összehasonlították a progeszteron- (P4) és a vemhességi fehérje (PAG) RIA-tesztek megbízhatóságát. A PAG-teszttel a nem vemhes állatok nagyobb ... [more ▼]

A szerzők a juhok vemhességének korai megállapítására összehasonlították a progeszteron- (P4) és a vemhességi fehérje (PAG) RIA-tesztek megbízhatóságát. A PAG-teszttel a nem vemhes állatok nagyobb biztonsággal voltak felismerhetők. Nagyszámú állaton (n=949 és 764) végzett rectalis ultrahangvizsgálattal a vemhességet pontosabban tudták megállapítani, ha az állatokat 12 óráig koplaltatták és vizsgálat közben a hasfalat a tőgy előtt felemelték. Az ultrahangvizsgálat és a PAG-teszt eredményeinek összehasonlításával megállapították, hogy az utóbbi megbízhatóbb eredményt ad. [less ▲]

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See detailEarly pregnancy diagnosis in sheep by progesterone and pregnancy-associated glycoprotein tests
Karen, A.; Beckers, Jean-François ULg; Sulon, Joseph ULg et al

in Theriogenology (2003), 59(9), 1941-1948

The aim of this study was to compare the accuracy of the progesterone (P4) and pregnancy associated glycoprotein (PAG) tests for determination of early pregnancy in sheep. Estrus was synchronized in 182 ... [more ▼]

The aim of this study was to compare the accuracy of the progesterone (P4) and pregnancy associated glycoprotein (PAG) tests for determination of early pregnancy in sheep. Estrus was synchronized in 182 Awassi x Merino ewes and blood samples were collected at Days 0 (day of the insemination), 18, 22, 29, 36, and 50 after artificial insemination (AI). Plasma P4 concentrations at Days 0 and 18 were determined by double antibody radioimmunoassay, while PAG concentrations at Days 22, 29, 36 and 50 were determined by a heterologous, double-antibody radioimmunoassay (RIA) using the bovine PAG 67 kDa subunit as tracer and standard and rabbit antiserum raised against a mixture of caprine 55 and 59 kDa PAG subunits as the first antibody. The discriminatory value for diagnosis of pregnancy by the P4 and the PAG-RIA tests was greater than or equal to1 ng/ml. Based on lambing data, the accuracy for diagnosing pregnant (sensitivity) and non-pregnant ewes (specificity) and predictivity of both tests were calculated. The sensitivity, specificity, positive and negative predictive values for P4 and PAG tests were 100, 95.4, 81.6, and 100% at Day 18 (P4) and 93.5, 100, 100 and 98.7% at Day 22 (PAG), respectively. For diagnosis of non-pregnant ewes the PAG test had significantly higher specificity than the P4 test (P < 0.05). It is concluded that ovine pregnancy can be reliably diagnosed at Day 22 after AI by using a heterologous radioimmunoassay of PAG. [less ▲]

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See detailEarly pregnancy diagnosis in sheep by progesterone and pregnancy-associated glycoprotein tests.
Karen, A.; Beckers, Jean-François ULg; Sulon, J. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(1), 8

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See detailEarly prognostic index and late exercise test comapred in survivors from acute myocardial infarction
Chapelle, Jean-Paul ULg; Smeets, J. P.; El Allaf, M. et al

Poster (1987, September 05)

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See detailEarly pronostic index and late exercise test compared in survivors from acute myocardial infarction
Chapelle, Jean-Paul ULg; Smeets, J. P.; El Allaf, M. et al

in European Heart Journal Supplements : Journal of the European Society of Cardiology (1987), 8(suppl.2), 11

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See detailEarly reactions of light-induced protochlorophyllide and chlorophyllide transformations analyzed in vivo at room temperature with a diode array spectrofluorometer
Boddi, B.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (2003), 69(1), 31-39

The steps of protochlorophyllide (Pchlide) photoreduction and subsequent chlorophyllide (Chlide) transformations which occur in the seconds to minutes time-scale were studied using a diode array ... [more ▼]

The steps of protochlorophyllide (Pchlide) photoreduction and subsequent chlorophyllide (Chlide) transformations which occur in the seconds to minutes time-scale were studied using a diode array spectrofluorometer in dark-grown barley leaves. The intensity of the excitation light was varied between 3 and 2500 mumol m(-2) s(-1) and a series of fluorescence spectra were recorded at room temperature in the seconds and minutes time scales. In certain experiments, 77-K emission spectra were measured with the same equipment. The high quality of the spectra allowed us to run spectral resolution studies which proved the occurrence, at room temperature, of multiple Pchlide and Chlide forms found previously in 77-K spectra. The comparison of the 77-K and room-temperature spectra showed that the fluorescence yields of the nonphotoactive 633-nm Pchlide form and of the Chlide product emitting at 678 nm were temperature independent. The fluorescence intensity of aggregated NADPH-pigment-POR complexes (photoactive 656-nm Pchlide and 693-nm Chlide forms) were strongly increased at 77 K, while that of the NADP(+)-Chlide-POR (684-686-nm Chlide form) was much less affected by temperature. Information was obtained also about the dynamics of the transformation of pigment forms in the light at different photon densities. At low light intensities, the phototransformation of the 642-644-nm Pchlide form was faster than that of the 654-656-nm form. The relative amplitudes of Gaussian components related to different Chlide forms found after exposure to a constant amount of photons strongly depended on the light intensity used. Strong quenching of all Chlide components occurred upon prolonged exposure to high intensity light. These effects are discussed by considering the interconversion processes between different forms of the pigment-protein complexes, their relative fluorescence yields and energy migration processes. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailEarly release of myeloperoxydase and lactoferin after direct stenting in patient presented for unstable angina
Gach, Olivier ULg; Biemar, C.; Pierard, Luc ULg et al

in European Heart Journal (2004), 25(Suppl. S), 450-450

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See detailEarly release of neutrophil markers of activation after direct stenting in patients with unstable angina
Gach, Olivier ULg; Biemar, Christian; Nys, Monique ULg et al

in Coronary Artery Disease (2005), 16(1), 59-65

Objective To assess polymorphonuclear neutrophils activation after stenting in acute coronary syndromes studied by myeloperoxydase, lactoferrin and elastase release in this clinical setting. Methods ... [more ▼]

Objective To assess polymorphonuclear neutrophils activation after stenting in acute coronary syndromes studied by myeloperoxydase, lactoferrin and elastase release in this clinical setting. Methods Myeloperoxydase, lactoferrin, elastase, C-reactive protein and cytokines serum levels were assessed in 20 patients undergoing catheterization for unstable angina. Serial sampling starting before arteriography and continued up to 24 h was carried out in 15 patients undergoing direct stenting (group A) and in five patients assessed by coronary angiography only (group B). Results Myeloperoxydase, lactoferrin and elastase levels remained unchanged following catheterization, whereas a significant increase in myeloperoxydase (P=0.0009) and lactoferrin (P=0.004) was observed after stenting. No change in levels of tumour necrosis factor alpha, interleukin (IL)-8 and IL-12 was found in group B after catheterization at the different sampling times, although IL-8 and IL-12 levels increased transiently following stenting. IL-6 values increased in both groups. Baseline values of C-reactive protein were similar in each group. A progressive increase in C-reactive protein was noted in both groups and appeared to be larger following stenting (group A: P=0.0002; group B: P=0.01). Conclusions In patients with unstable angina, stenting is associated by immediate neutrophil activation followed by release of inflammatory cytokines (IL-6, IL-8, IL-12) and C-reactive protein elevation. This study points out a potential role of myeloperoxydase as a trigger for inflammatory reaction in patients with unstable coronary syndromes undergoing percutaneous coronary intervention. (C) 2005 Lippincott Williams WillZins. [less ▲]

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See detailEarly response of lymphocyte proteins after gamma-radiation
Turtoi, Andrei ULg; Srivastava, Alok; Sharan, Rajesh et al

in Journal of Radioanalytical & Nuclear Chemistry (2007), 274(2), 435-39

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See detailEarly retention in kindergarten: risk factors and pathways in primary education
Lafontaine, Dominique ULg; Chenu, Florent ULg; Dupont, Virginie

Conference (2013, August 31)

In French-speaking Belgium, about 4% of the children are retained in kindergarten. What are the pupils’ characteristics and the school context variables predictive of the retention in kindergarten? What ... [more ▼]

In French-speaking Belgium, about 4% of the children are retained in kindergarten. What are the pupils’ characteristics and the school context variables predictive of the retention in kindergarten? What are the pathways in primary education of “retained” pupils compared to their peers who started 1st grade “on time”? How can this early retention be explained? A broad database with entire cohorts has been used for studying the risk factors and the pupils’ school careers in primary education. Moreover, teachers’ beliefs about retention, learning and teaching have been investigated through a questionnaire administered to a representative sample of preschool and 1st grade teachers. The multilevel regression analyses show that the following variables are significantly predictive of retention in kindergarten: month of birth, gender, socioeconomic status, country of birth and at the school level, mean school social intake. Investigation about teachers’ belief shows that the vast majority of teachers are convinced that retention in kindergarten is beneficial for later achievement and not detrimental at a psychological level. Preschool and 1st grade teachers share some mutual expectations about the level of prerequisites for entering 1st grade. Even if they are no formal instructions or benchmarks, kids who are not “ready” should not enter 1st grade, but rather stay one more year in kindergarten. Those results can be related to the “culture” of the education system in Belgium, a non-comprehensive one: pupils with learning difficulties are kept apart from their age group or peers through grade retention, early tracking and special education. [less ▲]

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See detailEarly retention in kindergarten: risk factors and school career in French-speaking Belgium primary education
Lafontaine, Dominique ULg; Chenu, Florent ULg; Dupont, Virginie ULg

Conference (2013, August 31)

In French-speaking Belgium, about 4% of the children are retained in kindergarten. What are the pupils’ characteristics and the school context variables predictive of the retention in kindergarten? What ... [more ▼]

In French-speaking Belgium, about 4% of the children are retained in kindergarten. What are the pupils’ characteristics and the school context variables predictive of the retention in kindergarten? What are the pathways in primary education of “retained” pupils compared to their peers who started 1st grade “on time”? How can this early retention be explained? A broad database with entire cohorts has been used for studying the risk factors and the pupils’ school careers in primary education. Moreover, teachers’ beliefs about retention, learning and teaching have been investigated through a questionnaire administered to a representative sample of preschool and 1st grade teachers. The multilevel regression analyses show that the following variables are significantly predictive of retention in kindergarten: month of birth, gender, socioeconomic status, country of birth and at the school level, mean school social intake. Investigation about teachers’ belief shows that the vast majority of teachers are convinced that retention in kindergarten is beneficial for later achievement and not detrimental at a psychological level. Preschool and 1st grade teachers share some mutual expectations about the level of prerequisites for entering 1st grade. Even if they are no formal instructions or benchmarks, kids who are not “ready” should not enter 1st grade, but rather stay one more year in kindergarten. Those results can be related to the “culture” of the education system in Belgium, a non-comprehensive one: pupils with learning difficulties are kept apart from their age group or peers through grade retention, early tracking and special education. [less ▲]

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See detailEarly retirement in Europe: A call for action
Jousten, Alain ULg

in CESIFO Forum (2001), 4

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