Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailEarly and transient reverse transcription during primary deltaretroviral infection of sheep.
Pomier, Carole; Alcaraz, Maria Teresa Sanchez; Debacq, Christophe et al

in Retrovirology (2008), 5

BACKGROUND: Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has ... [more ▼]

BACKGROUND: Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has only been investigated during the chronic phase of the infection when they mainly spread through the clonal expansion of their host cells, vary through a somatic mutation process without evidence for reverse transcriptase (RT)-associated substitution. Primary infection of a new organism necessary involves allogenic cell infection and thus reverse transcription. RESULTS: Here we demonstrate that the primary experimental bovine leukemia virus (BLV) infection of sheep displays an early and intense burst of horizontal replicative dissemination of the virus generating frequent RT-associated substitutions that account for 69% of the in vivo BLV genetic variability during the first 8 months of the infection. During this period, evidence has been found of a cell-to-cell passage of a mutated sequence and of a sequence having undergone both RT-associated and somatic mutations. The detection of RT-dependent proviral substitution was restricted to a narrow window encompassing the first 250 days following seroconversion. CONCLUSION: In contrast to lentiviruses, deltaretroviruses display two time-dependent mechanisms of genetic variation that parallel their two-step nature of replication in vivo. We propose that the early and transient RT-based horizontal replication helps the virus escape the first wave of host immune response whereas somatic-dependent genetic variability during persistent clonal expansion helps infected clones escape the persistent and intense immune pressure that characterizes the chronic phase of deltaretrovirus infection. [less ▲]

Detailed reference viewed: 37 (21 ULg)
Peer Reviewed
See detailEarly assessment of risk in patients with acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, A.; Smeets, J. P. et al

in European Heart Journal (1981), 2(3), 187-96

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailEarly asteroseismic results from Kepler: structural and core parameters of the hot B subdwarf KPD 1943+4058 as inferred from g-mode oscillations
Van Grootel, Valérie ULg; Charpinet, Stéphane; Fontaine, Gilles et al

in Astrophysical Journal Letters (2010), 718

We present a seismic analysis of the pulsating hot B subdwarf KPD 1943+4058 (KIC 005807616) on the basis of the long-period, gravity-mode pulsations recently uncovered by Kepler. This is the first time ... [more ▼]

We present a seismic analysis of the pulsating hot B subdwarf KPD 1943+4058 (KIC 005807616) on the basis of the long-period, gravity-mode pulsations recently uncovered by Kepler. This is the first time that g-mode seismology can be exploited quantitatively for stars on the extreme horizontal branch, all previous successful seismic analyses having been confined so far to short-period, p-mode pulsators. We demonstrate that current models of hot B subdwarfs can quite well explain the observed g-mode periods, while being consistent with independent constraints provided by spectroscopy. We identify the 18 pulsations retained in our analysis as low- degree (l = 1 and 2), intermediate-order (k = −9 through −58) g-modes. The periods (frequencies) are recovered, on average, at the 0.22% level, which is comparable to the best results obtained for p-mode pulsators. We infer the following structural and core parameters for KPD 1943+4058 (formal fitting uncertainties only): Teff = 28,050 ± 470 K, log g = 5.52 ± 0.03, M∗ = 0.496 ± 0.002 M⊙, log (Menv/M∗) = −2.55 ± 0.07, log (1 − Mcore/M∗) = −0.37 ± 0.01, and Xcore (C+O) = 0.261 ± 0.008. We additionally derive the age of the star since the zero-age extended horizontal branch 18.4 ± 1.0 Myr, the radius R = 0.203 ± 0.007 R⊙, the luminosity L = 22.9 ± 3.13 L⊙, the absolute magnitude MV = 4.21 ± 0.11, the reddening index E(B − V ) = 0.094 ± 0.017, and the distance d = 1180 ± 95 pc. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailEarly Bifrontal Brain Injury: Disturbances in Cognitive Function Development
Bonnier, Christine; Costet, Aurélie; Hmaimess, Ghassan et al

in Neurology Research International (2010)

We describe six psychomotor, language, and neuropsychological sequential developmental evaluations in a boy who sustained a severe bifrontal traumatic brain injury (TBI) at 19 months of age. Visuospatial ... [more ▼]

We describe six psychomotor, language, and neuropsychological sequential developmental evaluations in a boy who sustained a severe bifrontal traumatic brain injury (TBI) at 19 months of age. Visuospatial, drawing, and writing skills failed to develop normally. Gradually increasing difficulties were noted in language leading to reading and spontaneous speech difficulties. The last two evaluations showed executive deficits in inhibition, flexibility, and working memory. Those executive abnormalities seemed to be involved in the other impairments. In conclusion, early frontal brain injury disorganizes the development of cognitive functions, and interactions exist between executive function and other cognitive functions during development. [less ▲]

Detailed reference viewed: 66 (6 ULg)
Peer Reviewed
See detailEarly bifrontal brain injury: sequential neuropsychological developmental features
Bonnier, Christine; Potelle, Dominique; Buelens, M et al

in Revista de neurologia (2006)

Detailed reference viewed: 2 (1 ULg)
Full Text
Peer Reviewed
See detailEarly boost and slow consolidation in motor skill learning
Hotermans, C.; Peigneux, Philippe ULg; Maertens De Noordhout, Alain ULg et al

in Learning & Memory (Cold Spring Harbor, N.Y.) (2006), 13(5, Sep-Oct), 580-583

Motorskill learning is a dynamic process that continues covertly after training has ended and eventually leads to delayed increments in performance. Current theories Suggest that this off-line improvement ... [more ▼]

Motorskill learning is a dynamic process that continues covertly after training has ended and eventually leads to delayed increments in performance. Current theories Suggest that this off-line improvement takes time and appears only after several hours. Here we show an early transient and short-lived boost in performance, emerging as early as 5-30 min after training but no longer observed 4 h later. This early boost is predictive of the performance achieved 48 h later, Suggesting its functional relevance for memory processes. [less ▲]

Detailed reference viewed: 12 (3 ULg)
Peer Reviewed
See detailEarly Bronze Age Houses in Upper Mesopotamia: An Evidence of Dwellings or Private Enterprises?
Mas, Juliette ULg

in Workshop Household and Household Economies in 3rd Millennium B.C. Syro-Mesopotamia Proceedings (in press)

This paper deals with the research I carried out on domestic architecture and private economy during Early Bronze Age in Upper-Mesopotamia. Archaeological records, as well as textual evidence, has been ... [more ▼]

This paper deals with the research I carried out on domestic architecture and private economy during Early Bronze Age in Upper-Mesopotamia. Archaeological records, as well as textual evidence, has been used to try to define private households activities and their relationships with official institutions. Households were the main source of production, distribution and consumption during the Early Bronze Age. As it seems that these private economic entities produced goods and crafts in their own houses, analyzing domestic architecture could be a way to approach Mesopotamian economic activities. In Northern Mesopotamia the economic system was already strongly articulated; beyond palatial organizations it was also largely based on private group activities, often structured by kinship. [less ▲]

Detailed reference viewed: 31 (3 ULg)
Peer Reviewed
See detailEarly changes in myocardial carbohydrate oxidative metabolism during E. Coli endotoxin infusion in dog
D'Orio, Vincenzo ULg; EL ALLAF, D; VAIRA, S et al

in Archives Internationales de Physiologie et de Biochimie (1985), 93

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailEarly clinical experience with subcutaneous naratriptan in the acute treatment of migraine: a dose-ranging study.
Dahlof, C.; Hogenhuis, L.; Olesen, J. et al

in European Journal of Neurology (1998), 5(5), 469-477

Naratriptan is a novel, potent agonist at the 5HT1B/1D receptor. A total of 335 migraine patients were treated in this randomized, double-blind, placebo-controlled, dose-ranging, in-clinic study, to ... [more ▼]

Naratriptan is a novel, potent agonist at the 5HT1B/1D receptor. A total of 335 migraine patients were treated in this randomized, double-blind, placebo-controlled, dose-ranging, in-clinic study, to evaluate the efficacy, safety and tolerability of five doses of subcutaneous (sc) naratriptan (0.5, 1, 2.5, 5 or 10 mg) in comparison with sc sumatriptan (6 mg) and placebo in the acute treatment of a moderate/severe migraine attack. Headache relief [reduction of headache severity from moderate or severe (grade 2/3) to mild or none (grade 1/0)] at 1 and 2 h after each dose, was reported by a statistically significantly higher proportion of patients for all doses of sc naratriptan and sc sumatriptan (6 mg) than for placebo. The percentages of patients with headache relief at 2 h post-dose were: naratriptan (0.5 mg) 65%, (1 mg) 75%, (2.5 mg) 83%, (5 mg) 94% and (10 mg) 91%; sumatriptan (6 mg) 89%; placebo 41%, (P < 0.005). The earliest report of a statistically significant difference compared with placebo for the times assessed was with sc naratriptan (10 mg) at 10 min post-dose (P = 0.023). The percentages of patients reporting adverse events were dose-related; sc naratriptan (0.5 mg) 33%, (1 mg) 29%, (2.5 mg) 43%, (5 mg) 59% and (10 mg) 71%; sc sumatriptan 53%; placebo 22%. There were no clinically significant changes in electrocardiogram (ECG), vital signs or laboratory parameters. Systemic exposure increased proportionally to the dose, the absorption of sc naratriptan was rapid (tmax = 10 min) and the half-life was 5 h. In conclusion, sc naratriptan was an effective and well-tolerated acute treatment for migraine. Copyright 1998 Lippincott Williams & Wilkins [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
See detailEarly colonization of Posidonia oceanica (L.) Delile by epiphytes: Comparison between natural and artificial seagrass leaves
Pete, Dorothée ULg; Gobert, Sylvie ULg; Lepoint, Gilles ULg et al

in Pergent-Martini, Christine; El Asmi, Souha; Le Ravallec, Célia (Eds.) Proceedings of the third Mediterranean symposium on marine vegetation (2007, March)

Posidonia oceanica is an important marine Magnoliophyta of the Mediterranean coastal zone that can form dense meadows. The leaves of this seagrass are colonized by a lot of organisms, from bacteria to ... [more ▼]

Posidonia oceanica is an important marine Magnoliophyta of the Mediterranean coastal zone that can form dense meadows. The leaves of this seagrass are colonized by a lot of organisms, from bacteria to polychaetes and algae. However, the early stages of colonization are not well known. A preliminary is proposed to examine the nine first days of colonization by epiphytes on natural leaves and on Artificial Seagrass Units (ASUs). Aims of this work were to understand which species are the first to set up, to compare colonization on both leaves and to determine the interest of ASUs in ecological studies. It was shown that the setting up of epiphytes on the bases of both leaves is rapid (first algae on the second day) but the number of organisms increases quicker on ASUs than on natural leaves and on the smooth faces than the rough ones. Shannon-Wiener diversity and evenness were higher for the P. oceanica leaves and the use of Bray-Curtis similarity index showed that colonisation is not similar (between 20 and 30 % similarity) on both leaves for the same day. It can be explained by the lower colonization rate of natural leaves. This lower rate is probably due to a less developed biofilm on natural leaves than on ASUs, to a difficult access to the bases of P. oceanica leaves for epiphytes and microoganisms, and the production of phenol compounds by the plant. Even if ASUs used here do not seem to be similar to natural leaves in early stages of colonization, they could be used in ecological studies thanks to their rapid covering by epiphytes. [less ▲]

Detailed reference viewed: 120 (16 ULg)
Full Text
Peer Reviewed
See detailEarly contribution of phonological awareness and later influence of phonological memory throughout reading acquisition
Nithart, C.; Demont, E.; Majerus, Steve ULg et al

in Journal of Research in Reading (2011), 34

Detailed reference viewed: 65 (11 ULg)
See detailAn Early Cretaceous ichthyosaur from SE France: implications on the evolution of post-Liassic Ichthyosauria
Fischer, Valentin ULg; Clément, Arnaud; Guiomar, Myette et al

Conference (2010, June)

A complete ichthyosaur rostrum with 124 associated teeth was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a late ... [more ▼]

A complete ichthyosaur rostrum with 124 associated teeth was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a late Valanginian age (Neocomites peregrinus Zone, Olcostephanus nicklesi Subzone) for this fossil, which consequently represents the first diagnostic ichthyosaur ever reported from Valanginian strata. Despite its incompleteness, this specimen is perfectly consistent with Aegirosaurus leptospondylus WAGNER 1853 and is therefore referred to this rare taxon. This specimen thus greatly increases the temporal and geographic biozones of this taxon, which was previously restricted to the Tithonian (Upper Jurassic) lithographic limestones of Bavaria (southern Germany). Moreover, it indicates that Late Jurassic ichthyosaurs actually crossed the Jurassic-Cretaceous boundary with a much lighter diversity drop than previously supposed. Finally, tooth morphology and wear pattern suggest that Aegirosaurus belonged to the “Pierce II/ Generalist” feeding guild sensu Massare (1987; 1997), which was hitherto not represented in post-Liassic ichthyosaurs. [less ▲]

Detailed reference viewed: 134 (4 ULg)
Peer Reviewed
See detailEarly decision support for net zero energy buildings design using building performance simulation
Attia, Shady ULg; Gratia, Elisabeth; De Herde, Andre et al

in Clean Technology for Smart Cities and Buildings (2013, September)

This paper aims to investigate the use of building performance simulation tools as a method of informing the design decision of NZEBs. The aim of this study is to evaluate the effect of a simulation-based ... [more ▼]

This paper aims to investigate the use of building performance simulation tools as a method of informing the design decision of NZEBs. The aim of this study is to evaluate the effect of a simulation-based decision aid, ZEBO, on informed decision-making using sensitivity analysis. The objective is to assess the effect of ZEBO and other BPS tools on three specific outcomes: (i) knowledge and satisfaction when using simulation for NZEB design; (ii) users’ decision-making attitudes and patterns, and (iii) performance robustness based on an energy analysis. The paper utilizes three design case studies comprising a framework to test the use of BPS tools. Two types of data were collected, mainly preference and performance data. The preference data were used to collect information from participants using self-reported metrics. The performance data were used to collect information on the energy performance of the final design. The energy evaluations were compared with the results of a quantitative assessment of the overall design performance. Finally the results were compared and presented. The paper provides results that shed light on the effectiveness of sensitivity analysis as an approach for informing the design decisions of NZEBs. [less ▲]

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailEarly design simulation tools for net zero energy buildings: a comparison of ten tools
Attia, Shady ULg; De Herde, André

in Conference Proceedings of 12th International Building Performance Simulation Association, 2011 (2011, November)

Given the challenges to design Net Zero Energy Buildings (NZEBs), the use of Building Performance Simulation (BPS) tools during early design phases has been indispensable. In this context, we compare ten ... [more ▼]

Given the challenges to design Net Zero Energy Buildings (NZEBs), the use of Building Performance Simulation (BPS) tools during early design phases has been indispensable. In this context, we compare ten early design BPS tools. The aim is to define the potential of using and integrating the tools by architect during the design of NZEBs. The examined tools include HEED, e-Quest, ENERGY-10, Vasari, Solar Shoebox, Open Studio Plug-in, IES-VE- Ware, DesignBuilder, ECOTECT and BEopt. The comparison is based on two different criteria sets. The results describe tools limitations and major requirements to meet the NZEBs objective implications. [less ▲]

Detailed reference viewed: 42 (2 ULg)
Full Text
See detailEarly detection of alien plants in xeric Natura 2000 sites in Southern Belgium
Monty, Arnaud ULg; Frisson, Gwenn; Mahy, Grégory ULg

Poster (2012)

The Natura 2000 network consists of sites designated by the member States of the European Union, under the Habitats and Birds Directives. Setting up that network is one of the biggest challenge in nature ... [more ▼]

The Natura 2000 network consists of sites designated by the member States of the European Union, under the Habitats and Birds Directives. Setting up that network is one of the biggest challenge in nature conservation in Europe, since habitats and species for which Natura 2000 sites are designated must be maintained in a “favorable conservation status”. Little is known so far, however, about how Natura 2000 sites are invaded by exotics species. Xeric habitats of high biological value included in the Natura 2000 network are among the most species-rich in Southern Belgium. They include calcareous grasslands, sandy meadows, dry heathlands, boxwood stands, siliceous rocks and calcareous rocks. We randomly sampled 15% of sites in each of these six categories (with a minimum of five sites per category) , with a total of 86 sites out of 470 existing sites. In each site, we recorded the presence/absence of 63 alien plants know to develop in xeric habitats (species list based on Verloove (2006) and expert’s personnal observations.), and estimated species cover. 25 naturalized alien plant species were observed in xeric habitats of the Natura 2000 network in Southern Belgium. Generally, alien species populations were still limited. [less ▲]

Detailed reference viewed: 11 (1 ULg)