Emerging hyphenated analytical techniques for POPs

in Organohalogen Compounds (2008), 70

Emerging hyphenated and comprehensive multi-dimensional techniques for the measurement of persistant organic pollutants (POPs)

Conference (2007, October)

Emerging Hyphenated and Comprehensive Multi-Dimensional Techniques for the Measurement of POPs in Food.

Conference (2006, June)

Emerging International Standards : If a dream could come true

Conference (2009, May 27)

Emerging Patterns of Depoliticization and Engagement to Inform the Future of Science and Technology Studies: A Case Study in Nanotechnologies

Conference (2009)

In this paper, we address the issue of the future of a particular field of research in social science: Science and Technology Studies (STS). Although this is a very young research field, its history is ... [more ▼]

In this paper, we address the issue of the future of a particular field of research in social science: Science and Technology Studies (STS). Although this is a very young research field, its history is already diverse and its evolutions are fastly moving on. Its rapid expansion and its characteristic feature of crossing disciplinary boundaries are making it an interesting case to study, which takes a particular place in the overall history – and future – of social changes. As we shall indicate, STS have an increasing committment for the resolution of sociotechnical controversies. In this paper, we problematise this particular position by underlying the implicit politics of STS research and how they will shape the future of that particular field. Our approach is threefold. First, we give a brief overview of the history of the field and we point out the main evolutions since the developement of the Social Construction of Technology approach (SCOT) in the 1980s that long influenced the field. By doing so, we underline the epistemological critical tradition that gave the field some of its particularities that we address. We show how this tradition brought important insights of “political” nature within the development of the field. Second, our ambition is to highlight new patterns of evolution of the STS field, emphasizing the trends towards both a greater depoliticisation and a more engaged research. By “depoliticisation”, we intend to analyse the dynamics of institutionalisation of the field which adopts resources and tools to legitimate itself among the social scientific community. By “engaged” research, we will explore the evolutions of the STS field as inherently political. The field does have an implicit statement in favor of changing social order and an increasing willingness to actually influence that social change. In that respect, research projects in STS often have underlying politics, as we shall demonstrate. Third, we give a concrete example of these new patterns occuring, relying on the growing importance of nanotechnologies, both in the STS literature and research projects. We consider this case study to be intertwined with the development of STS as a field of research. In that sense, we stress that nanotechnologies happened to be a powerful tool for legitimation for the STS community. Therefore, we — as STS scholars — suggest instrumentalizing the interest we have in nanotechnologies in order to observe the evolutions of our field of research. Then, nanotechnologies will constitute an interesting ground to perform a test that will show depoliticisation and engagement as patterning the STS field. [less ▲]

The Emerging Role of Exercise Testing and Stress Echocardiography in Valvular Heart Disease

in Journal of the American College of Cardiology (2009), 54(24), 2251-60

Exercise testing has an established role in the evaluation of patients with valvular heart disease and can aid clinical decision making. Because symptoms may develop slowly and indolently in chronic valve ... [more ▼]

Exercise testing has an established role in the evaluation of patients with valvular heart disease and can aid clinical decision making. Because symptoms may develop slowly and indolently in chronic valve diseases and are often not recognized by patients and their physicians, the symptomatic, blood pressure, and electrocardiographic responses to exercise can help identify patients who would benefit from early valve repair or replacement. In addition, stress echocardiography has emerged as an important component of stress testing in patients with valvular heart disease, with relevant established and potential applications. Stress echocardiography has the advantages of its wide availability, low cost, and versatility for the assessment of disease severity. The versatile applications of stress echocardiography can be tailored to the individual patient with aortic or mitral valve disease, both before and after valve replacement or repair. Hence, exercise-induced changes in valve hemodynamics, ventricular function, and pulmonary artery pressure, together with exercise capacity and symptomatic responses to exercise, provide the clinician with diagnostic and prognostic information that can contribute to subsequent clinical decisions. Nevertheless, there is a lack of convincing evidence that the results of stress echocardiography lead to clinical decisions that result in better outcomes, and therefore large-scale prospective randomized studies focusing on patient outcomes are needed in the future. [less ▲]

Emerging Roles for Proteinases in Cancer

in Invasion & Metastasis (1997), 17(5), 221-39

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these ... [more ▼]

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these processes was initially thought to be the destruction of extracellular matrices. However, recent evidence suggests that they mainly affect tumor growth rather than invasion. Proteinases can indeed generate active matrix protein fragments, influence the release, the activation and the bioavailability of growth factors, and consequently modulate tumor cell growth, apoptosis and angiogenesis. Additionally, proteinases, their receptors and/or inhibitors can be directly involved in cell migration and in the processing or shedding of cell surface proteins. Further elucidation of the functions of proteinases is essential for the development of novel anticancer strategies. [less ▲]

Emerging Technologies for Automatic Target Recognition

Conference (1990, June)

Emerging therapies for ionizing radiation-associated skin field carcinogenesis.

in Expert Opinion on Pharmacotherapy (2009), 10(5), 813-21

BACKGROUND: Radiodermatitis in its acute and chronic presentations represents a set of specific adverse effects resulting from ionizing radiations. Skin-field cancerization is another condition associated ... [more ▼]

BACKGROUND: Radiodermatitis in its acute and chronic presentations represents a set of specific adverse effects resulting from ionizing radiations. Skin-field cancerization is another condition associated to or independent of clinically recognizable radiodermatitis. This condition leads to the risk of later occurrence of skin malignancies. METHOD: Review of the current and most pertinent peer-reviewed publications with the addition of personal perspectives. RESULT/CONCLUSION: The presence of field cancerization encompasses subclinical changes, precursors of malignant alterations, as well as single or multiple primary neoplasms and local neoplastic recurrences. These tumours commonly require repeated treatments over time and cause significant morbidity. In general, specific tumour-directed treatments using ablative or destructive techniques require regular follow-up and screening for disclosing any further neoplasm. Another strategy corresponding to field-directed treatment targets a larger area of irradiated skin to reduce the risk of developing second neoplasms and local recurrences. Imiquimod is an immune response modifier of the imidazoquinoline class. It is the archetype drug used to control skin-field carcinogenesis. Cryotherapy, topical 5-fluorouracil, diclofenac and conventional photodynamic therapy are supposed to bring effects differing by their indications, healing rates and remission rates. The possibility of inducting a radiation recall dermatitis by some of these therapeutic modalities has not been thoroughly evaluated, and at present cannot be ruled out with confidence. [less ▲]

Emesis in dogs: a review

in Journal of Small Animal Practice (2010), 51