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See detailDisorders of consciousness: Belgium Federal Project
Vanhaudenhuyse, Audrey ULg

Conference (2012)

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See detailDisorders of consciousness: coma, vegetative and minimally conscious states
Gosseries, Olivia ULg; Vanhaudenhuyse, Audrey ULg; Bruno, Marie-Aurélie ULg et al

in D. Cvetkovic & I. Cosic (Ed.) States of Consciousness: Experimental Insights into Meditation, Waking, Sleep and Dreams (2011)

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See detailDisorders of consciousness: further pathophysiological insights using motor cortex transcranial magnetic stimulation.
Lapitskaya, Natallia; Coleman, Martin R.; Nielsen, Joergen Feldbaek et al

in Progress in Brain Research (2009)

Transcranial magnetic stimulation (TMS) is a noninvasive means of investigating the function, plasticity, and excitability of the human brain. TMS induces a brief intracranial electrical current, which ... [more ▼]

Transcranial magnetic stimulation (TMS) is a noninvasive means of investigating the function, plasticity, and excitability of the human brain. TMS induces a brief intracranial electrical current, which produces action potentials in excitable cells. Stimulation applied over the motor cortex can be used to measure overall excitability of the corticospinal system, somatotopic representation of muscles, and subsequent plastic changes following injury. The facilitation and inhibition characteristics of the cerebral cortex can also be compared using the modulatory effect of a conditioning stimulus preceding a test stimulus. So called paired-pulse protocols have been used in humans and animals to assess GABA (gamma-amino-butyric acid)-ergic function and may have a future role directing therapeutic interventions. Indeed, repetitive magnetic stimulation, where intracranial currents are induced by repetitive stimulation higher than 1 Hz, has been shown to modulate brain responses to sensory and cognitive stimulation. Here, we summarize information gathered using TMS with patients in coma, vegetative state, and minimally conscious state. Although in the early stages of investigation, there is preliminary evidence that TMS represents a promising tool by which to elucidate the pathophysiological sequelae of impaired consciousness and potentially direct future therapeutic interventions. We will discuss the methodology of work conducted to date, as well as debate the general limitations and pitfalls of TMS studies in patients with altered states of consciousness. [less ▲]

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See detailDisorders of consciousness: Moving from passive to resting state and active paradigms
Bruno, Marie-Aurélie ULg; Soddu, Andrea ULg; Demertzi, Athina ULg et al

in Cognitive Neuroscience (2010), 1(1), 193203

Following coma, some patients will recover wakefulness without signs of consciousness (i.e., vegetative state) or may show nonreflexive movements but with no ability for functional communication (i.e ... [more ▼]

Following coma, some patients will recover wakefulness without signs of consciousness (i.e., vegetative state) or may show nonreflexive movements but with no ability for functional communication (i.e., minimally conscious state). Currently, there remains a high rate of misdiagnosis of the vegetative state. The increasing use of fMRI and EEG tools permits the clinical characterization of these patients to be improved. We first discuss “resting metabolism” and “passive activation” paradigms, used in neuroimaging and evoked potential studies, which merely identify neural activation reflecting “automatic” processing—that is, occurring without the patient’s willful intervention. Secondly, we present an alternative approach consisting of instructing subjects to imagine well-defined sensorymotor or cognitive-mental actions. This strategy reflects volitional neural activation and, hence, witnesses awareness. Finally, we present results on blood-oxgen-level-dependent “default mode network”/resting state studies that might be a promising tool in the diagnosis of these challenging patients. [less ▲]

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See detailDisorders of consciousness: What's in a name?
Gosseries, Olivia ULg; Bruno, Marie-Aurélie ULg; Chatelle, Camille ULg et al

in NeuroRehabilitation (2011), 28

Following a coma, some patients may “awaken” without voluntary interaction or communication with the environment. More than 40 years ago this condition was coined coma vigil or apallic syndrome and later ... [more ▼]

Following a coma, some patients may “awaken” without voluntary interaction or communication with the environment. More than 40 years ago this condition was coined coma vigil or apallic syndrome and later became worldwide known as “persistent vegetative state”. About 10 years ago it became clear that some of these patients who failed to recover verbal or nonverbal communication did show some degree of consciousness – a condition called “minimally conscious state”. Some authors questioned the usefulness of differentiating unresponsive “vegetative” from minimally conscious patients but subsequent functional neuroimaging studies have since objectively demonstrated differences in residual cerebral processing and hence, we think, conscious awareness. These neuroimaging studies have also demonstrated that a small subset of unresponsive “vegetative” patients may show unambiguous signs of consciousness and command following inaccessible to bedside clinical examination. These findings, together with negative associations intrinsic to the term “vegetative state” as well as the diagnostic errors and their potential effect on the treatment and care for these patients gave rise to the recent proposal for an alternative neutral and more descriptive name: unresponsive wakefulness syndrome. We here give an overview of PET and (functional) MRI studies performed in these challenging patients and stress the need for a separate ICD9CM diagnosis code and MEDLINEMeSH entry for “minimally conscious state” as the lack of clear distinction between vegetative state/unresponsive wakefulness syndrome and minimally conscious state may encumber scientific studies in the field of disorders of consciousness. [less ▲]

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See detailDisorders of lambs thyroid by a glucosinolate metabolite: the 5-vinyl-l,3-oxazolidine-2-thione (5-VOT)
Mabon, N.; Mandiki, S.; Bister, J.-L. et al

Conference (2003)

The impact of 5-VOT on thyroid was studied in two lambs. They received ad libitum water, hay and concentrates without rapeseed from ten days of age till weaning (65 days of age). At 85 days of age, one of ... [more ▼]

The impact of 5-VOT on thyroid was studied in two lambs. They received ad libitum water, hay and concentrates without rapeseed from ten days of age till weaning (65 days of age). At 85 days of age, one of them was fed with the same diet but mixed with 100g/d of a rapeseed containing high level of progoitrin: 71.4µmol/g DM (variety Jet Neuf). Blood samples were taken fortnightly for the determination of TSH (Thyroid Stimulating Hormone), T3 (Tri-iodothyronin) and T4 (thyroxin) plasma concentrations. [less ▲]

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See detailDisorders of mitochondrial function
Debray, François-Guillaume ULg; Lambert, M.; Mitchell, G. A.

in Current Opinion in Pediatrics (2008), 20(4), 471-482

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See detailDisparités au sein du système éducatif en Communauté française de Belgique
Lafontaine, Dominique ULg

in Eduquer et former. Théories et pratiques (1995), 7

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See detailLes disparités et les dynamiques territoriales. Introduction méthodologique
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (1994), (30), 5-14

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory ... [more ▼]

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory; secondly, the choice of spatial analysis levels, temporal limits and indicators and finally research into explanations. These are always very complicated and pratical despite the contribution of the major regional development theories and the new inquiries of regional science in the field of perceptions, networks and actors' roll. [less ▲]

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See detailDisparities in dialysis treatment and outcomes for Dutch and Belgian children with immigrant parents.
Schoenmaker, Nikki J.; Tromp, Wilma F.; van der Lee, Johanna H. et al

in Pediatric nephrology (Berlin, Germany) (2012), 27(8), 1369-79

BACKGROUND: In Belgium and the Netherlands, up to 40% of the children on dialysis are children with immigrant parents of non-Western European origin (non-Western). Concerns exist regarding whether these ... [more ▼]

BACKGROUND: In Belgium and the Netherlands, up to 40% of the children on dialysis are children with immigrant parents of non-Western European origin (non-Western). Concerns exist regarding whether these non-Western patients receive the same quality of care as children with parents of Western European origin (Western). We compared initial dialysis, post-initial treatment, and outcomes between non-Western and Western patients on dialysis. METHODS: All children <19 years old on chronic dialysis in the Netherlands and Belgium between September 2007 and May 2011 were included in the study. Non-Western patients were defined as children of whom one or both parents were born in non-Western countries. RESULTS: Seventy-nine of the 179 included patients (44%) were non-Western children. Compared to Western patients, non-Western patients more often were treated with hemodialysis (HD) instead of peritoneal dialysis (PD) as first dialysis mode (52 vs. 37%, p = 0.046). Before renal transplantation, non-Western patients were on dialysis for a median (range) of 30 (5-99) months, vs. 15 (0-66) months in Western patients (p = 0.007). Renal osteodystrophy was diagnosed in 34% of non-Western vs. 18% of Western patients (p = 0.028). The incidence rate ratio [95% confidence interval] for acute peritonitis was 2.44 [1.43-4.17] (p = 0.032) for non-Western compared to Western patients. CONCLUSIONS: There are important disparities between children on chronic dialysis with parents from Western European origin and those from non-Western European origin in the choice of modality, duration, and outcomes of dialysis therapy. [less ▲]

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See detailLa disparition d'une organisation internationale : l'Union de l'Euope occidentale (1954-2011)
Dumoulin, André ULg

in Annuaire français de relations internationales 2011 (2011)

Bras alluvionnaire du courant d'unification européenne (1948), bras armé intergouvernemental des intérêts européens de sécurité (1980), pilier européen de sécurité au profit de l'OTAN et de l'Union (1992 ... [more ▼]

Bras alluvionnaire du courant d'unification européenne (1948), bras armé intergouvernemental des intérêts européens de sécurité (1980), pilier européen de sécurité au profit de l'OTAN et de l'Union (1992), outil d'imprégnation otanienne (1995), organe résiduel en voie « d’amaigrissement forcé » (2000), l'Union occidentale, mais surtout l'Union de l'Europe occidentale, furent ainsi les enjeux de rivalités entre européistes et atlantistes, entre l'OTAN et l'Union, avant d'être « amaigrie » puis « condamnée » au profit de cette dernière. Ces affaiblissements successifs jusqu’à sa dénonciation ont fait de l'Union de l'Europe occidentale la seule organisation de sécurité et de défense qui fut vidée avec autant d'efficacité de sa substance par les capitales qui en étaient pourtant les premiers gardiens et les maîtres d'œuvre. [less ▲]

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See detailLa disparition de l'absorption
Kefer, Fabienne ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1995)

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See detailDispatcher-assisted telephone cardiopulmonary resuscitation using a French-language compression-only protocol in volunteers with or without prior life support training: A randomized trial.
Ghuysen, Alexandre ULg; Collas, D.; Stipulante, Samuel ULg et al

in Resuscitation (2011)

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to ... [more ▼]

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to evaluate a new French-language protocol in terms of its efficacy to help previously untrained volunteers in performing basic life support efforts of appropriate quality, and secondarily to investigate its potential utility in subjects with previous training. METHODS: Untrained volunteers were recruited among adults in a public movie centre and previously trained volunteers among undergraduate nursing students. Participants were randomly assigned to 'phone CPR' versus 'no phone CPR' by drawing sets of envelopes. Primary outcome measures were the results of the Cardiff evaluation test; the secondary measures were global scoring of a complete 5min period of CPR, in a manikin model of cardiac arrest. RESULTS: Out of 146 volunteers assessed for eligibility, 36 previously untrained candidates declined participation. 110 participants, distributed into four groups, completed the study: the previously untrained non-guided group (group A, n=30), the previously untrained guided group (group B, n=30), the previously trained non-guided group (group C, n=25) and the previously trained guided group (group D, n=25). Results of the Cardiff test and global evaluation of CPR performance revealed a significant improvement in group B as compared with group A, approaching the level of the group C. Previously trained guided bystanders had the best CPR scores, notably because of an improvement in the quality of airway management. CONCLUSION: When used by dispatchers, this new French-language algorithm offers the opportunity to help previously untrained bystanders initiate CPR. The same protocol may serve to guide volunteers with prior basic life support training to reach their best CPR performance. [less ▲]

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See detailDispense de permis d'urbanisme en Région wallonne (I)
Delnoy, Michel ULg

in Immobilier (1999), 21

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See detailDispense de permis d'urbanisme en Région wallonne (II)
Delnoy, Michel ULg

in Immobilier (1999), 22

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See detailDispense de permis d'urbanisme en Région wallonne (III)
Delnoy, Michel ULg

in Immobilier (1999), 23

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See detailDispense de permis d'urbanisme en Région wallonne (IV)
Delnoy, Michel ULg

in Immobilier (2000), 1

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See detailDispenses de permis d'urbanisme en Région wallonne
Delnoy, Michel ULg

in Immobilier (2001), 18

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