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See detailCrosstalk Modeling of Wnt, BMP and ERK Pathways during osteochondrogenic differentiation
Geris, Liesbet ULg; Vandeput, Maarten; Roberts, Scott et al

in proceedings of the International Symposium on Biomechanics and Biology of Bone Regeneration “From Functional Assessment To Guided Tissue Formation (2009, November)

The in vitro engineering of tissues may be achieved by mimicking in vivo tissue development. Although multiple skeletal tissue engineering applications already exist, the underlying mechanisms at protein ... [more ▼]

The in vitro engineering of tissues may be achieved by mimicking in vivo tissue development. Although multiple skeletal tissue engineering applications already exist, the underlying mechanisms at protein level are often poorly understood. Growth factors and protein pathways precisely navigate mesenchymal stem cells trough the correct cascades. A detailed understanding of these cascades will enable us to develop efficient and robust production methods, which are required for large scale tissue engineering applications. Multiple studies hypothesize that the Wnt/β-catenin pathway acts as a switching mechanism to determine the differential fate of esenchymal cells in osteoblasts or chondrocytes during skeletogenesis. The concentration of β-catenin is a key factor in this mechanism. Wnt upregulates the productionof β-catenin which in turn upregulates Runx2 and downregulates Sox9. High concentrations of Runx2 relative to Sox9 lead to osteoblasts, while the opposite situation leads to chondrocytes. Crosstalks of the Wnt pathway with other pathways such as that of BMP and ERK expand the amount of factors that can influence β-catenin, turning the linear signaling cascade into a complex network with multiple starting conditions. A mathematical model was derived from literature describing the pathways of BMP, Wnt and ERK as well as various crosstalks between these pathways that were suggested in literature. CellDesigner™ was used to formulate, solve and visualize the Ordinary Differential Equations describing the temporal evolution of the various model constituents. Multiple starting conditions (various concentrations of BMP, Wnt and ERK) were examined to clarify the crosstalk effect. Modeling various crosstalks proposed in literature resulted in a mutual inhibitory effect between Wnt and BMP signaling, an effect independently described in literature. Experiments are ongoing to corroborate the model predictions. [less ▲]

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See detailThe CROSTVOC project – an integrated approach to study the effect of stress on BVOC exchange between agricultural crops and grassland ecosystems and the atmosphere
Amelynck, Crist; Heinesch, Bernard ULg; Aubinet, Marc ULg et al

in Geophysical Research Abstracts (2015, April), 17

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions ... [more ▼]

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions and by increases in frequency and intensity of biotic or abiotic stress episodes. Indeed, several studies indicate changes in the emission patterns of constitutive BVOCs and emission of stress-induced BVOCs following heat, drought and oxidative stress, amongst others. Relating changes in BVOC emissions to the occurrence of one or multiple stressors in natural environmental conditions is not straightforward and only few field studies have dealt with it, especially for agricultural crop and grassland ecosystems. The CROSTVOC project aims to contribute in filling this knowledge gap in three ways. Firstly, it aims at performing long-term BVOC emission field measurements from maize (Zea mays L.) and wheat (Triticum aestivum L.), two important crop species on the global scale, and from grassland. This should lead to a better characterization of (mainly oxygenated) BVOC emissions from these understudied ecosystems, allowing a better representation of those emissions in air quality and atmospheric chemistry and transport models. BVOC fluxes are obtained by the Disjunct Eddy Covariance by mass scanning (DEC-MS) technique, using a hs-PTR-MS instrument for BVOC analysis. Secondly, the eddy covariance BVOC flux measurements (especially at the grassland site) will be accompanied by ozone flux, chlorophyll fluorescence, photosynthesis and soil moisture measurements, amongst others, to allow linking alterations in BVOC emissions to stress episodes. Simultaneously, automated dynamic enclosures will be deployed in order to detect specific abiotic and biotic stress markers by PTR-MS and identify them unambiguously by GC-MS. Thirdly, the field measurements will be accompanied by laboratory BVOC flux measurements in an environmental chamber in order to better disentangle the responses of the BVOC emissions to driving factors that co-occur in field conditions and to determine the influence of single abiotic stressors on BVOC emissions. Next to a general presentation, some preliminary results of the project will be shown. [less ▲]

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See detailCrowdsourced Monitoring, Citizen Empowerment and Data Credibility: The case of Observations.be
Farah, Jihad ULg

in Murgante, Beniamino; Sanjay, Misra; Rocha, Anna Maria (Eds.) et al Computational Science and its applications - ICCSA 2014 (2014)

Crowdsourcing is today a revolutionary phenomenon changing pro- foundly our ways of communicating and producing. This article is interested in two issues that are crucial to its development and impacts ... [more ▼]

Crowdsourcing is today a revolutionary phenomenon changing pro- foundly our ways of communicating and producing. This article is interested in two issues that are crucial to its development and impacts. On one hand, it in- vestigates the forms and limits of crowdsourcing-related citizen empowerment. It is less concerned by the now recognized fact that crowdsourcing is empower- ing, but rather focuses on the ways it does so and the architecture of the rela- tions between citizens, scientists and institutions in this new context. On the other, it discusses the question of credibility of data produced through crowd- sourcing. This question represents, in fact, the Achilles’ heel that destabilizes the rise of citizen power in the face of experts and institutions. In its discussion of these two issues, the article relies on a particularly interesting case study: the online platform of participatory monitoring of biodiversity in Belgium Observa- tions.be. The creation of databases is an occasion here for reflexivity, learning and mobilisation. It is also an occasion for the liberation of the lay citizen, as an individual, from the straightjackets delimiting the institutional, scientific and associative spaces where he remains a subject, a collaborator or a member – al- ways in a subordinate position. He becomes a peer producer, partner and discussant. More important, learning and action networks that develop in the platform cut transversally through the three spheres. We find unexpected and new cooperations between citizen, scientists and civil servants. Likewise, ac- tions developed through the platform, mainly reporting, counting campaigns and early alert systems attest new modes of action that transgress the functional and ontological division of the three spheres. [less ▲]

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See detailcrown rot disease of bananas
Lassois, Ludivine ULg; de Lapeyre de Bellaire

in Bautista-Banos, Silvia (Ed.) Postharvest Decay, control strategies (2014)

Detailed reference viewed: 66 (40 ULg)
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See detailCrown rot of banana: Preharvest factors involved in postharvest disease development and integrated control methods
Lassois, Ludivine ULg; Jijakli, Haissam ULg; Chillet, M. et al

in Plant Disease (2010), 94(6), 648-658

Detailed reference viewed: 79 (21 ULg)
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See detailCroyances de la population générale au sujet des manipulations vertébrales
Demoulin, Christophe ULg; Baeri, D.; TOUSSAINT, Geoffrey ULg et al

in Revue du Rhumatisme (2015, December), 82S

Detailed reference viewed: 44 (3 ULg)
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See detailLes croyances délétères des patients lombalgiques : revue narrative de la littérature
Demoulin, Christophe ULg; Roussel, Nathalie; Marty, Marc et al

in Revue Médicale de Liège (2016), 71(1), 40-46

Detailed reference viewed: 239 (20 ULg)
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See detailLes croyances des enseignants concernant le redoublement évoluent-elles au cours de leur formation initiale ?
Crahay, Marcel ULg; Ory, Patrick; Boraita, Fanny ULg

in Annales Scientifiques de la Faculté de Psychologie et Sciences de l'Education de l'Université "Ovidius" (2012)

Detailed reference viewed: 48 (4 ULg)
Peer Reviewed
See detailCroyances métacognitives et hallucinations
Laroi, Frank ULg

Conference (2010, November 18)

Detailed reference viewed: 20 (3 ULg)
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See detailLes croyances partagées et la question du lien social
Melice, Anne ULg

Conference given outside the academic context (2013)

Detailed reference viewed: 113 (15 ULg)
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See detailCroyances, pratiques et utilisations des tortues marines en médecine traditionnelle sur la côte ouest africaine: Bénin et Sénégal
Dossa, Justine; Diez, Marianne ULg; Hornick, Jean-Luc ULg et al

in Chéloniens : Biologie, écologie, Elevage, Conservation (2009), 14

Detailed reference viewed: 98 (25 ULg)
See detailLe CRP et ses opérateurs : les usages de la confiance
Remy, Céline ULg

Scientific conference (2013, December 12)

Detailed reference viewed: 12 (0 ULg)