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See detailDiagnosis of small bowel malabsorption syndromes in adults
Belaiche, Jacques ULg; Louis, Edouard ULg

in Acta Gastro-Enterologica Belgica (2006), 69(1, Jan-Mar), 31-37

Patients with malabsorption represent a small proportion of presentations with chronic diarrhea. In spite of some progress, the last twenty years were not very innovating in malabsorption investigations ... [more ▼]

Patients with malabsorption represent a small proportion of presentations with chronic diarrhea. In spite of some progress, the last twenty years were not very innovating in malabsorption investigations. Supporting history may direct investigations toward either the small bowel or pancreas. Serological testing for celiac disease will determine most cases without invasive investigation, but individuals suspected to have small bowel malabsorption, despite negative celiac serology, should have endoscopic distal duodenal biopsies taken to exclude other rare forms of small bowel enteropathy. This strategy has largely supplanted many older tests of small bowel function. [less ▲]

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See detailDiagnosis of the sediment transport in the Belgian Coastal Zone
Mercier, Christophe ULg; Delhez, Eric ULg

in Estuarine Coastal & Shelf Science (2007), 74(4), 670-683

Estimating the age of particles in marine environment constitutes an invaluable tool to understand the interactions between complex flows and sediment dynamics, particularly in highly energetic coastal ... [more ▼]

Estimating the age of particles in marine environment constitutes an invaluable tool to understand the interactions between complex flows and sediment dynamics, particularly in highly energetic coastal areas such as the Belgian Coastal Zone (Southern Bight in the North Sea). To this end, the Constituent Age and Residence time Theory-CART-introduced by Delhez, E.J.M., Campin, J.-M., Hirst, A.C., Deleersnijder, E. [1999a. Toward a general theory of the age in ocean modelling. Ocean Modelling 1, 17-27] for passive water constituents is extended to describe the sediment dynamics. It is then used in combination with a three-dimensional coupled hydrodynamic-sediment transport model to investigate sediment processes in the Belgian Coastal Zone focusing on two complementary aspects of the sediment dynamics: the internal sediment motion and redistribution within the Belgian coast; and the horizontal transport. (C) 2007 Elsevier Ltd. All rights reserved. [less ▲]

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See detailDiagnosis of the transport of adsorbed material in the Scheldt estuary: A proof of concept
Delhez, Eric ULg; Wolk, Frank ULg

in Journal of Marine Systems (2013), 128

Many contaminants can attach to suspended particles. Their transport differs therefore from the transport of dissolved substances, especially in highly turbid environment like estuaries. In this paper, we ... [more ▼]

Many contaminants can attach to suspended particles. Their transport differs therefore from the transport of dissolved substances, especially in highly turbid environment like estuaries. In this paper, we show how the Constituent Age and Residence time Theory (CART — www.climate.be/CART) can be adapted to quantify in a rigorous manner the transport rate of contaminants that are present in both the dissolved and adsorbed phases. On the basis of numerical experiment using a 1D model of the Scheldt estuary, it is shown that the interaction with suspended particles significantly affects the transport of contaminants with partition coefficients larger than 1000 ml/g. The mean transit time from Ghent to Vlissingen of such contaminants can reach 160 days while it is only 60 days for water and dissolved constituents. This increase of the transit time is mainly due to the fact that adsorbed constituents spend long periods of time on the bottom. Surprisingly, the downstream transport of adsorbed constituents in the water column appears more effective than that of dissolved constituents. This transport affects however a small fraction of the adsorbed constituent and is therefore not sufficient to compensate for the long resting phase on the bottom of the bulk of the constituent. The concept and methodology introduced in this paper are easily applicable to most model studies and provide powerful and flexible tools for the detailed understanding of the transport of contaminants in estuaries. In particular, the concept of age and modified ages taking into account specifically the time spent in the water column or in the bottom provide new diagnostic tools to understand and quantify the dynamics of contaminants. [less ▲]

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See detailDiagnosis of TSH secreting pituitary adenomas : A changing scene
Beckers, Albert ULg

in The 85th Annual Meeting of the Endocrine Society - Abstract book (2003)

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See detailDiagnosis of vertical velocities with the QG Omega equation: a relocation method to obtain pseudo-synoptic data sets
Rixen, Michel; Beckers, Jean-Marie ULg; Allen, J. T.

in Deep-Sea Research Part I, Oceanographic Research Papers (2001), 48(6), 1347-1373

The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from ... [more ▼]

The quantification of vertical motion and vertical fluxes is essential in our ability to predict and tolerate climate change. However, diagnostic estimations might be affected by the errors arising from the necessary compromise between spatio-temporal resolution and cost of hydrographic surveys. Observations of a numerical ocean model have been made in order to test the accuracy of different sampling strategies and their possible a-posteriori corrections. A simple first-order correction method, computing a pseudo-synoptic data set from a non-synoptic data set and involving a geostrophic relocation of the stations is shown to correct significantly the synopticity error in hydrographic data, derived QG vertical motion and vertical temperature fluxes. Sensitivity analyses also show that the lack of synopticity is more critical than other factors, including the sampling resolution, the level of no-motion and the analysis. (C) 2001 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailDiagnosis primary aldosteronism is it neccesary?
Krzesinski, Jean-Marie ULg

Learning material (2007)

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See detailDiagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis.
DEBRAY, François-Guillaume ULg; Mitchell, Grant A; Allard, Pierre et al

in Clinical Chemistry (2007), 53(5), 916-21

BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its ... [more ▼]

BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its diagnostic accuracy for differentiating between these 2 types of CLA has not been evaluated formally. METHODS: We conducted a retrospective study of all patients followed for mitochondrial diseases between 1985 and 2005 in a tertiary care pediatric hospital. RESULTS: At the recommended cut point of approximately 25, individual median L:P ratio demonstrated low sensitivity and specificity (77% and 91%, respectively) for differentiating between patients with enzymatically proven PDH-D (n = 11) and those with mitochondrial disease but normal pyruvate dehydrogenase (PDH) activity (non-PDH; n = 35). We observed a strong positive association between L:P ratio and blood lactate in non-PDH CLA, whereas this association was weak in PDH-D CLA. Consequently, patient classification based on median L:P ratio showed improved diagnostic accuracy at higher lactate concentrations: for lactate <2.5 mmol/L the area under the ROC curve was not statistically different from 0.5 (P = 0.3), whereas it was statistically different for lactate >2.5 mmol/L. In the 2.5 to 5.0 mmol/L lactate category, the sensitivity and specificity at an optimal cut point of 18.4 were 93% (95% CI, 77%-99%) and 71% (95% CI, 20%-96%), respectively; for lactate >5.0 mmol/L, with an optimal cut point of 25.8, sensitivity and specificity were 96% (95% CI, 77%-99%) and 100% (95% CI, 59%-100%), respectively. CONCLUSION: Usefulness of the L:P ratio for differentiating non-PDH and PDH-D types of CLA increases at higher lactate concentrations. [less ▲]

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See detailDiagnostic accuracy of computed tomography coronary angiography in routine practice
Davin, Laurent ULg; LANCELLOTTI, Patrizio ULg; Bruyere, P. J. et al

in Acta Cardiologica (2007), 62(4), 339-344

Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector ... [more ▼]

Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector spiral computed tomography (MSCT) for detecting coronary artery stenosis. Methods - A total of 88 consecutive patients (52 men, mean age 68 +/- 8 years) with atypical chest pain, stable angina or suspicion of ischaemia at stress test were studied by MSCT and invasive coronary angiography (ICA). The MSCT images and multiplanar reconstructions were analysed regarding the presence of >= 50% coronary artery lesion. Results - All 88 scans obtained at a mean heart rate of 68 8 beats/min were interpretable. Sixteen coronary segments were evaluated in each patient. Of the 1320 segments examined, 148 (11 %) showed poor image quality. A total of 150 significant lesions were detected using ICA, and 80 of 150 (53%) were detected by MSCT Sensitivity, specificity, positive and negative predictive values were as follows: 53%, 97%, 68%, and 94%. Fifty-four patients had >= 50% coronary stenosis. The diagnosis was confirmed by MSCT in 42 patients and correctly ruled out in 30. By patient-based analysis, positive and negative predictive values were 91 % and 71 %. Conclusion - Although its specificity is high, the sensitivity of 16-slice MSCT for detecting 2: 50% coronary stenosis in non-selected patients submitted to ICA is rather low suggesting that for daily practice the diagnostic value of this technique should be improved. [less ▲]

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See detailDiagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment.
Schnakers, Caroline ULg; Vanhaudenhuyse, Audrey ULg; Giacino, Joseph et al

in BMC Neurology (2009), 9

BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies ... [more ▼]

BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies have investigated the accuracy of this grave clinical diagnosis. In this study, we compared consensus-based diagnoses of VS and MCS to those based on a well-established standardized neurobehavioral rating scale, the JFK Coma Recovery Scale-Revised (CRS-R). METHODS: We prospectively followed 103 patients (55 +/- 19 years) with mixed etiologies and compared the clinical consensus diagnosis provided by the physician on the basis of the medical staff's daily observations to diagnoses derived from CRS-R assessments performed by research staff. All patients were assigned a diagnosis of 'VS', 'MCS' or 'uncertain diagnosis.' RESULTS: Of the 44 patients diagnosed with VS based on the clinical consensus of the medical team, 18 (41%) were found to be in MCS following standardized assessment with the CRS-R. In the 41 patients with a consensus diagnosis of MCS, 4 (10%) had emerged from MCS, according to the CRS-R. We also found that the majority of patients assigned an uncertain diagnosis by clinical consensus (89%) were in MCS based on CRS-R findings. CONCLUSION: Despite the importance of diagnostic accuracy, the rate of misdiagnosis of VS has not substantially changed in the past 15 years. Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus. [less ▲]

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See detailDiagnostic agronomique et agro-environnemental des successions culturales en Wallonie (Belgique).
Leteinturier, Béatrice; Tychon, Bernard ULg; Oger, Robert ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 27-38

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l ... [more ▼]

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l'échelle des régions agricoles qui composent le territoire de la Wallonie (Belgique). L'étude vise à dresser un diagnostic des performances qualitatives des successions culturales, à travers l'analyse individuelle de plusieurs de leurs composantes explicatives telles la qualité des précédents culturaux sur les cultures suivantes, le temps de retour moyen des cultures, le nombre de cultures apparaissant au cours de la succession et enfin la durée des périodes interculturales. Ces quatre composantes sont analysées à l'échelle parcellaire, les résultats étant agrégés au niveau régional. L'étude porte à la fois sur une analyse spatiale basée sur une période de 7 années, ainsi que sur une analyse temporelle visant à observer une éventuelle évolution, région par région, au cours de deux périodes successives de même durée. L'état des lieux ainsi dressé révèle des différences spatiales en termes de pratiques liées aux successions culturales, par contre, une quasi-stabilité dans le temps des paramètres analysés découle des résultats obtenus. Par ailleurs, si ces résultats contribuent à enrichir un état des lieux de l'agriculture en Wallonie, ils peuvent en outre servir de valeurs de référence pour un suivi global de l'évolution des pratiques agricoles régionales. [less ▲]

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See detailDiagnostic and therapeutic management of carcinoma of unknown primary: radio-imaging investigations.
Jerusalem, Guy ULg; Rorive, Andrée ULg; Ancion, G. et al

in Annals of Oncology (2006), 17 Suppl 10

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See detailDiagnostic antenatal des affections du stystème nerveux central: résultats préliminaires d'une série multicentrique européenne de 350 cas
Evrard, philippe; Misson, Jean-Paul ULg; belpaire, marie-claude

in Journal Français d'Echographie [=JFE] (1984), 2(4), 123-123

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See detailDiagnostic antenatal des affections du stystème nerveux central: résultats préliminaires d'une série multicentrique européenne de 350 cas
Evrard, Philippe; Misson, Jean-Paul ULg; Belpaire, M-Cl

in Journal français d'échographie (1984), 2(4), 123-123

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See detailDiagnostic assessment procedures
de Landsheere, Gilbert ULg

in Walberg, Herbert J.; Haertel, Geneva D. (Eds.) The international encyclopedia of educational evaluation (1990)

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See detailDiagnostic biologique de l'infarctus du myocarde
Chapelle, Jean-Paul ULg

Conference (1994, May 26)

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See detailDiagnostic challenge of desmoplastic melanoma.
Quatresooz, Pascale ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Trends in Cancer Research (2007), 3

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See detailDiagnostic challenges of cystic fibrosis in patients of African origin.
Mutesa, Leon; Bours, Vincent ULg

in Journal of Tropical Pediatrics (2009), 55(5), 281-6

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See detailDiagnostic Characteristics and Therapeutic Responses in Acromegaly : The Liège Acromegaly Survey
Tikhomirova, M.; Petrossians, Patrick ULg; Daly, Adrian ULg et al

in 50th Meeting of the German Endocrine Society and 23rd Meeting of Dutch Endocrine Society : Essen, Germany, 1-4 March 2006 (2006, March)

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