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See detailDiagnosis primary aldosteronism is it neccesary?
Krzesinski, Jean-Marie ULg

Learning material (2007)

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See detailDiagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis.
DEBRAY, François-Guillaume ULg; Mitchell, Grant A; Allard, Pierre et al

in Clinical Chemistry (2007), 53(5), 916-21

BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its ... [more ▼]

BACKGROUND: Although the blood lactate-to-pyruvate (L:P) molar ratio is used to distinguish between pyruvate dehydrogenase deficiency (PDH-D) and other causes of congenital lactic acidosis (CLA), its diagnostic accuracy for differentiating between these 2 types of CLA has not been evaluated formally. METHODS: We conducted a retrospective study of all patients followed for mitochondrial diseases between 1985 and 2005 in a tertiary care pediatric hospital. RESULTS: At the recommended cut point of approximately 25, individual median L:P ratio demonstrated low sensitivity and specificity (77% and 91%, respectively) for differentiating between patients with enzymatically proven PDH-D (n = 11) and those with mitochondrial disease but normal pyruvate dehydrogenase (PDH) activity (non-PDH; n = 35). We observed a strong positive association between L:P ratio and blood lactate in non-PDH CLA, whereas this association was weak in PDH-D CLA. Consequently, patient classification based on median L:P ratio showed improved diagnostic accuracy at higher lactate concentrations: for lactate <2.5 mmol/L the area under the ROC curve was not statistically different from 0.5 (P = 0.3), whereas it was statistically different for lactate >2.5 mmol/L. In the 2.5 to 5.0 mmol/L lactate category, the sensitivity and specificity at an optimal cut point of 18.4 were 93% (95% CI, 77%-99%) and 71% (95% CI, 20%-96%), respectively; for lactate >5.0 mmol/L, with an optimal cut point of 25.8, sensitivity and specificity were 96% (95% CI, 77%-99%) and 100% (95% CI, 59%-100%), respectively. CONCLUSION: Usefulness of the L:P ratio for differentiating non-PDH and PDH-D types of CLA increases at higher lactate concentrations. [less ▲]

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See detailDiagnostic accuracy of computed tomography coronary angiography in routine practice
Davin, Laurent ULg; LANCELLOTTI, Patrizio ULg; Bruyere, P. J. et al

in Acta Cardiologica (2007), 62(4), 339-344

Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector ... [more ▼]

Objectives - The recent newer advances in computed tomography have dramatically changed our approach to imaging cardiac disease. This study sought to compare the diagnostic value of 16-multi-detector spiral computed tomography (MSCT) for detecting coronary artery stenosis. Methods - A total of 88 consecutive patients (52 men, mean age 68 +/- 8 years) with atypical chest pain, stable angina or suspicion of ischaemia at stress test were studied by MSCT and invasive coronary angiography (ICA). The MSCT images and multiplanar reconstructions were analysed regarding the presence of >= 50% coronary artery lesion. Results - All 88 scans obtained at a mean heart rate of 68 8 beats/min were interpretable. Sixteen coronary segments were evaluated in each patient. Of the 1320 segments examined, 148 (11 %) showed poor image quality. A total of 150 significant lesions were detected using ICA, and 80 of 150 (53%) were detected by MSCT Sensitivity, specificity, positive and negative predictive values were as follows: 53%, 97%, 68%, and 94%. Fifty-four patients had >= 50% coronary stenosis. The diagnosis was confirmed by MSCT in 42 patients and correctly ruled out in 30. By patient-based analysis, positive and negative predictive values were 91 % and 71 %. Conclusion - Although its specificity is high, the sensitivity of 16-slice MSCT for detecting 2: 50% coronary stenosis in non-selected patients submitted to ICA is rather low suggesting that for daily practice the diagnostic value of this technique should be improved. [less ▲]

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See detailDiagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment.
Schnakers, Caroline ULg; Vanhaudenhuyse, Audrey ULg; Giacino, Joseph et al

in BMC Neurology (2009), 9

BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies ... [more ▼]

BACKGROUND: Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies have investigated the accuracy of this grave clinical diagnosis. In this study, we compared consensus-based diagnoses of VS and MCS to those based on a well-established standardized neurobehavioral rating scale, the JFK Coma Recovery Scale-Revised (CRS-R). METHODS: We prospectively followed 103 patients (55 +/- 19 years) with mixed etiologies and compared the clinical consensus diagnosis provided by the physician on the basis of the medical staff's daily observations to diagnoses derived from CRS-R assessments performed by research staff. All patients were assigned a diagnosis of 'VS', 'MCS' or 'uncertain diagnosis.' RESULTS: Of the 44 patients diagnosed with VS based on the clinical consensus of the medical team, 18 (41%) were found to be in MCS following standardized assessment with the CRS-R. In the 41 patients with a consensus diagnosis of MCS, 4 (10%) had emerged from MCS, according to the CRS-R. We also found that the majority of patients assigned an uncertain diagnosis by clinical consensus (89%) were in MCS based on CRS-R findings. CONCLUSION: Despite the importance of diagnostic accuracy, the rate of misdiagnosis of VS has not substantially changed in the past 15 years. Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus. [less ▲]

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See detailDiagnostic agronomique et agro-environnemental des successions culturales en Wallonie (Belgique).
Leteinturier, Béatrice; Tychon, Bernard ULg; Oger, Robert ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 27-38

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l ... [more ▼]

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l'échelle des régions agricoles qui composent le territoire de la Wallonie (Belgique). L'étude vise à dresser un diagnostic des performances qualitatives des successions culturales, à travers l'analyse individuelle de plusieurs de leurs composantes explicatives telles la qualité des précédents culturaux sur les cultures suivantes, le temps de retour moyen des cultures, le nombre de cultures apparaissant au cours de la succession et enfin la durée des périodes interculturales. Ces quatre composantes sont analysées à l'échelle parcellaire, les résultats étant agrégés au niveau régional. L'étude porte à la fois sur une analyse spatiale basée sur une période de 7 années, ainsi que sur une analyse temporelle visant à observer une éventuelle évolution, région par région, au cours de deux périodes successives de même durée. L'état des lieux ainsi dressé révèle des différences spatiales en termes de pratiques liées aux successions culturales, par contre, une quasi-stabilité dans le temps des paramètres analysés découle des résultats obtenus. Par ailleurs, si ces résultats contribuent à enrichir un état des lieux de l'agriculture en Wallonie, ils peuvent en outre servir de valeurs de référence pour un suivi global de l'évolution des pratiques agricoles régionales. [less ▲]

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See detailDiagnostic and therapeutic management of carcinoma of unknown primary: radio-imaging investigations.
Jerusalem, Guy ULg; Rorive, Andrée ULg; Ancion, G. et al

in Annals of Oncology (2006), 17 Suppl 10

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See detailDiagnostic antenatal des affections du stystème nerveux central: résultats préliminaires d'une série multicentrique européenne de 350 cas
Evrard, philippe; Misson, Jean-Paul ULg; belpaire, marie-claude

in Journal Français d'Echographie [=JFE] (1984), 2(4), 123-123

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See detailDiagnostic antenatal des affections du stystème nerveux central: résultats préliminaires d'une série multicentrique européenne de 350 cas
Evrard, Philippe; Misson, Jean-Paul ULg; Belpaire, M-Cl

in Journal français d'échographie (1984), 2(4), 123-123

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See detailDiagnostic assessment procedures
de Landsheere, Gilbert ULg

in Walberg, Herbert J.; Haertel, Geneva D. (Eds.) The international encyclopedia of educational evaluation (1990)

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See detailDiagnostic biologique de l'infarctus du myocarde
Chapelle, Jean-Paul ULg

Conference (1994, May 26)

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See detailDiagnostic challenge of desmoplastic melanoma.
Quatresooz, Pascale ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Trends in Cancer Research (2007), 3

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See detailDiagnostic challenges of cystic fibrosis in patients of African origin.
Mutesa, Leon; Bours, Vincent ULg

in Journal of Tropical Pediatrics (2009), 55(5), 281-6

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See detailDiagnostic Characteristics and Therapeutic Responses in Acromegaly : The Liège Acromegaly Survey
Tikhomirova, M.; Petrossians, Patrick ULg; Daly, Adrian ULg et al

in 50th Meeting of the German Endocrine Society and 23rd Meeting of Dutch Endocrine Society : Essen, Germany, 1-4 March 2006 (2006, March)

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See detailLe diagnostic clinique et les examens complémentaires en pneumologie chez le chien et le chat
Clercx, Cécile ULg

in Nouveau praticien vétérinaire, Hors série : diagnostic et examens complémentaires (2004)

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See detailDiagnostic communautaire
Gosset, Christiane ULg

in Actes des Rencontres européennes : Approche communautaire de la santé et inégalités sociales (2001)

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See detailDiagnostic criteria for renovascular hypertension
Krzesinski, Jean-Marie ULg

in Acta Chirurgica Belgica (2002), 102(3), 159-166

Renovascular hypertension is a clinical situation characterized by high blood pressure in the presence of renal ischemia mainly related to atherosclerotic or fibromuscular dysplasic narrowing of the renal ... [more ▼]

Renovascular hypertension is a clinical situation characterized by high blood pressure in the presence of renal ischemia mainly related to atherosclerotic or fibromuscular dysplasic narrowing of the renal artery (ies). This diagnosis is often "a posteriori" validated, because the discovery of a significant renal artery stenosis is not obligatory responsible of the blood pressure elevation. This article proposes a diagnostic strategy for exploring patient with this suspected secondary cause of hypertension before proposing an invasive approach (intra-arterial angiography) possibly followed by a revascularization. However, the methods for exploring such population are mainly based on patient characteristics and local expertise and habits. These must thus be individualized. First, clinical symptoms or signs frequently associated with hypertension and renal artery stenosis must be searched. If present, a non invasive and functional exploration of the renal arteries is to be proposed (Captopril radioisotope renography, colour duplex sonography) followed by magnetic resonance angiography or spiral computer tomography angiography if the clinical suspicion index is moderate or high. If this is very high, an intra-arterial arteriography could immediately be performed if not too dangerous. On the opposite site, if the clinical index is low, it is recommended to follow clinically and to treat risk factors. [less ▲]

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See detailDiagnostic d'infarctus du myocarde au stade aigu: aspects biochimiques
Chapelle, Jean-Paul ULg

Conference (1996, November 28)

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