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See detail. Do innervation of germinal centre and contacts between FDC and nerve fibers be keys to understand the susceptibility difference between bovines and humans to the BSE agent?
Defaweux, Valérie ULg; Dorban, G.; Antoine, Nadine ULg et al

Poster (2008, October)

Background: In regard to BSE and vCJD, the agent tropism for lymphoid tissues is completely different even if the infectious strain responsible and the way of inoculation are identical. During vCJD, the ... [more ▼]

Background: In regard to BSE and vCJD, the agent tropism for lymphoid tissues is completely different even if the infectious strain responsible and the way of inoculation are identical. During vCJD, the infectious agent crosses the digestive barrier and multiplies in lymphoid organs, before progressively reaching the brain. Indeed, in vCJD, it accumulates in the ileum, tonsils, spleen and appendix of infected individuals. In contrast, in cattle, the BSE agent has a low affinity for lymphoid tissues and mainly accumulates in the nervous system. During preclinical stages, infectivity, other than that in the peripheral nervous system or central nervous system, is confined in the distal ileum of orally infected cattle. So, it appears that, at least in the case of BSE and vCJD, host properties can influence the accumulation of the infectious agent in lymphoid organs. Objectives and methods: In this study, we analysed by confocale microscopy the mucosal innervation and the interface between nerve fibres and FDC in bovine and human tonsils using a panel of antibodies. Since differences in the innervation of lymphoid organs depending on species and on age have been reported, we analysed two categories of bovines (calves less than 12 months old and bovines older than 24 months) and two categories of humans (patients less than 5 years old and patients older than 25 years). Results: In both species, ways of innervation by-passing germinal centres could be postulated: nerve fibres are widely distributed in antigen/cell traffic area: the lamina propria, the interfollicular zone and the lymphoepithelial area. We pointed out that, only in tonsils of bovines older than 24 months, nerve fibres are observed to be in contact with FDC. In contrast, in human tonsils, no nerve fibres established contacts with FDC, whatever the age. Discussion: Innervation of germinal centres can be said to be an age-dependent dynamic process in bovines. The weak innervation of the secondary lymphoid organs could thus be a rate-limiting step to neuroinvasion in humans. This species difference could influence the way of neuroinvasion and thus, the susceptibility of bovines and humans to the BSE agent. [less ▲]

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See detailDo large companies ignore formal sustainability management controls? A exploration amongst corporate practices
Crutzen, Nathalie ULg; Schaltegger, Stefan

in Proceedings of the 2014 EMAN conference (2014, March)

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See detailDo leaching experiments affect the Sm-Nd signature of deep-sea sediments? The example of the northern North Atlantic
Innocent, Christophe; Fagel, Nathalie ULg; Stevenson, Ross

in Canadian Journal of Soil Science (1999), 79

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See detailDo lignin wastes arising from cellulosic ethanol biorefinery act as radical scavenging agents?
Vanderghem, Caroline ULg; Jacquet, Nicolas ULg; Richel, Aurore ULg

in Australian Journal of Chemistry (in press)

Lignin is a co-product from the biorefinery and paper industry. Its non-energetic valorization remains a field of extensive R&D developments. In this perspective, this study is undertaken to evaluate the ... [more ▼]

Lignin is a co-product from the biorefinery and paper industry. Its non-energetic valorization remains a field of extensive R&D developments. In this perspective, this study is undertaken to evaluate the radical scavenging ability of some herbaceous lignins. These lignins, extracted from Miscanthus (Miscanthus x giganteus) or Switchgrass (Panicum Virgatum L.), are selected as benchmarks for this study as a function of their chemical structure and average molecular weight. These technical lignins, side-products in the bioethanol production process, are found to display a moderate antioxidant activity as evaluated by the DPPH (1,1-diphenyl-2-picrylhydrazil) free radical scavenging test system. A correlation between the radical scavenging properties and the molecular features is proposed and discussed. Infrared spectroscopy is evaluated as a straightforward qualitative prediction tool for the radical scavenging capacity. [less ▲]

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See detailDo local Authorities Face the Dutch Way of Consuming the Ardennes ?
Schmitz, Serge ULg

in Cawley, Mary (Ed.) The sustainability of Rural Systems : Local and Global Challenges and Opportunities (2011, August)

One theoretical recommendation to develop sustainable rural tourism is to base its development on the local resources. This should embed the tourist activity to the local society, avoid an easy ... [more ▼]

One theoretical recommendation to develop sustainable rural tourism is to base its development on the local resources. This should embed the tourist activity to the local society, avoid an easy delocalisation, and help to brand the destination. The Belgian Ardennes is a close recreation spot to Dutch people. The paper examines the local resources that attract Dutch tourists and the way how regional and local authorities deal with this tourist development. Based on key actors’ interviews and on in depth analysis of the promotional material produced both by authorities and commercial companies, the paper underlines seven ways to sell and to consume the Ardennes. Due to the lack of entrepreneurship by locals and because the Dutch tourism enterprises know better the Dutch tourists, these enterprises hold a large share of the tourist activities in the Ardennes. These Dutch investments change the destination as well as the local identity. While at the beginning, the Dutch companies developed a tourism based on nature and rural landscape, they diversified their activities up to offland tourism and the “disneyfication” of the places. If this Belgian case study follows more or less the well known “life cycle tourist destination”, the originality of the paper is to stress the difficulties and the opportunities of authorities to regulate tourism development and to maintain the quality of local resources. [less ▲]

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See detailDo males and females gammarids defend themselves differently during chemical stress ?
Gismondi, Eric ULg; Cossu-Leguille, Carole; Beisel, Jean-Nicolas

in Aquatic Toxicology (2013), 140-141

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See detailDo monitoring and counselling boost the job finding rates of the long-term unemployed ?
Fonder, Muriel; Lejeune, Bernard ULg

Conference (2008, June 13)

In July 2004, the Belgian government launched a new monitoring and counselling program targeted at the long-term unemployed. In this new program, people over 13 months unemployment are warned that their ... [more ▼]

In July 2004, the Belgian government launched a new monitoring and counselling program targeted at the long-term unemployed. In this new program, people over 13 months unemployment are warned that their job-search efforts will be monitored 8 months later. At the same time, they are invited to participate actively in the support (job search, training) programs provided for by the Regional Employment Agencies, whose supply was expanded. This reform has been implemented gradually : it focused the unemployed under 30 years in 2004, then the 30-40 year-old unemployed in 2005, and finally the 40-50 year-old unemployed in 2006. This paper aims at evaluate the effect, in terms of transition from unemployment to employment and/or training, of this new program for the 30-40 years old in Wallonia. Using the fact that the reform was implemented gradually, the effect of the program is estimated by difference-in-differences, based on (single exit and two exits) discrete duration models. The results suggest that the program has had a very large relative effect, although limited in absolute terms, regarding transition to training for almost all the treated unemployed. They also show that the program has had a substantial relative effect, although limited in absolute terms as well, with regard to transition to employment for the majority of the treated unemployed. [less ▲]

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See detailDo Mutual Fund Investors Still Trust Standard Risk-Adjusted Performance Measures?
Bodson, Laurent ULg; Cave, Arnaud; Sougné, Danielle ULg

E-print/Working paper (2012)

We study the relationship between the risk-adjusted performance of mutual funds and their money flows (i.e. their subscriptions and redemptions). Testing the most traditional risk-adjusted performance ... [more ▼]

We study the relationship between the risk-adjusted performance of mutual funds and their money flows (i.e. their subscriptions and redemptions). Testing the most traditional risk-adjusted performance measures, we identify the ones which best explain the flows of equity, bond or mixed funds. The risk-adjusted performance measures which attract the most the attention from investors are the Information ratios (mono- and multi-factor), the M-squared and the Sharpe ratios (traditional Sharpe ratios and Sharpe MVaR). We may conclude that fund managers who want to maximize their AuM (and, if applicable, increase their AuM based fees) must mainly focus their efforts on improving these standard performance measures. Furthermore, we also demonstrate that the performance-flow relationship is concave then convex. Indeed, amongst the funds with a negative performance, those achieving the worst results are affected by disproportionately high net outflows whereas, on the opposite side of the spectrum, the most successful funds experience much higher capital inflows. [less ▲]

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See detailDo Mutual Fund Investors Still Trust Standard Risk-Adjusted Performance Measures?
Sougné, Danielle ULg; Bodson, Laurent ULg; Cave, Arnaud

E-print/Working paper (2012)

We study the relationship between the past performance of mutual funds and their capital flows (i.e. their subscriptions and redemptions). Testing the most traditional risk-adjusted performance measures ... [more ▼]

We study the relationship between the past performance of mutual funds and their capital flows (i.e. their subscriptions and redemptions). Testing the most traditional risk-adjusted performance measures, we identify the ones which best explain the flows of US equity mutual funds. [less ▲]

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See detailDo Mutual Fund Investors Still Trust Standard Risk-Adjusted Performance Measures?
Sougné, Danielle ULg; Bodson, Laurent ULg; Cave, Arnaud

Conference (2012, August)

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See detailDo new methods of investigation allow faster assessment of drugs efficacy in osteoarthritis?
Abadie, Eric ULg; Avouac, B.; Bouvenot, G. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 2

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See detailDo patient with osteoporotic hip fracture recover their initial health-related quality of life?
Ethgen, Olivier ULg; Tancredi, Annalisa ULg; Jacques, J. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 66

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See detailDo patients with osteoporotic hip fracture recover their initial health-related quality of life?
Ethgen, Olivier ULg; Tancredi, Annalisa ULg; Jacques, Jessica ULg et al

in Osteoporosis International (2004, May), 15(Suppl.1), 50

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See detailDo Personality Traits Modulate the Effect of Emotional Visual Stimuli on Auditory Information Processing?
Mardaga, Solange; Hansenne, Michel ULg

in Journal of Individual Differences (2009), 30(1), 28-34

Several lines of evidence attest robust relationships between personality dimensions and emotions, including cognitive aspect of emotion. More particularly, many studies reported strong relationships ... [more ▼]

Several lines of evidence attest robust relationships between personality dimensions and emotions, including cognitive aspect of emotion. More particularly, many studies reported strong relationships between extraversion, the behavioral activation system (BAS), and the cognitive processing of positive information, on the one hand, and between neuroticism, the behavioral inhibition system (BIS), and the processing of negative information, on the other hand. Recently, DePascalis, Awari, Matteucci, and Mazzocco (2005) reported that personality traits modulated the effect of the emotional visual stimuli on the mismatch negativity (MMN). The aim of the present study was to replicate these data and extend them to other personality dimensions. Auditory MMN was recorded in normal subjects simultaneously to the presentation of emotional pictures selected as neutral, positive, or negative from the International Affective Picture System, and presented in randomized order. The results support the recent finding that personality (namely, BIS and harm avoidance) modulates the influence of emotional (negative) context on auditory information processing. The present findings suggest that the modulation by personality of change detection in the unattended environment as a function of context valence is limited to unpleasant context. [less ▲]

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See detailDo Photobiont Switch and Cephalodia Emancipation Act as Evolutionary Drivers in the Lichen Symbiosis? A Case Study in the Pannariaceae (Peltigerales)
Magain, Nicolas ULg; Sérusiaux, Emmanuël ULg

in PLoS ONE (2014), 9(2), 89876

Lichen symbioses in the Pannariaceae associate an ascomycete and either cyanobacteria alone (usually Nostoc; bipartite thalli) or green algae and cyanobacteria (cyanobacteria being located in dedicated ... [more ▼]

Lichen symbioses in the Pannariaceae associate an ascomycete and either cyanobacteria alone (usually Nostoc; bipartite thalli) or green algae and cyanobacteria (cyanobacteria being located in dedicated structures called cephalodia; tripartite thalli) as photosynthetic partners (photobionts). In bipartite thalli, cyanobacteria can either be restricted to a well-delimited layer within the thallus (‘pannarioid’ thalli) or spread over the thallus that becomes gelatinous when wet (‘collematoid’ thalli). We studied the collematoid genera Kroswia and Physma and an undescribed tripartite species along with representatives of the pannarioid genera Fuscopannaria, Pannaria and Parmeliella. Molecular inferences from 4 loci for the fungus and 1 locus for the photobiont and statistical analyses within a phylogenetic framework support the following: (a) several switches from pannarioid to collematoid thalli occured and are correlated with photobiont switches; the collematoid genus Kroswia is nested within the pannarioid genus Fuscopannaria and the collematoid genus Physma is sister to the pannarioid Parmeliella mariana group; (b) Nostoc associated with collematoid thalli in the Pannariaceae are related to that of the Collemataceae (which contains only collematoid thalli), and never associated with pannarioid thalli; Nostoc associated with pannarioid thalli also associate in other families with similar morphology; (c) ancestors of several lineages in the Pannariaceae developed tripartite thalli, bipartite thalli probably resulting from cephalodia emancipation from tripartite thalli which eventually evolved and diverged, as suggested by the same Nostoc present in the collematoid genus Physma and in the cephalodia of a closely related tripartite species; Photobiont switches and cephalodia emancipation followed by divergence are thus suspected to act as evolutionary drivers in the family Pannariaceae. [less ▲]

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See detailDo pictures of faces, and which ones, capture attention in the inattentional blindness paradigm?
Devue, Christel ULg; Laloyaux, Cédric ULg; Feyers, Dorothée ULg et al

in Perception (2009), 38(4), 552568

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning ... [more ▼]

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning of these stimuli rather than to their familiarity (Mack and Rock 1998). IB has mostly been investigated with schematic stimuli in previous work. In the present study, the generalisability of this finding was tested using photographic stimuli. In support to the view that faces constitute a special category of stimuli, it was found that pictures of faces resisted more to IB than pictures of common objects (Experiment 1) or than pictures of inverted faces (Experiment 2). In a third experiment, the influence of face familiarity and identity (ie the participant’s own face, a friend’s face and an unknown face) on IB rates was evaluated. Unexpectedly, no differential resistance to blindness across these three kinds of faces was found. In conclusion, picture of faces attracted attention more than pictures of objects or inverted faces in the IB paradigm. However, this effect was not dependent on face familiarity or identity. [less ▲]

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