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See detailDiagnosis of active acromegaly : is it time to amend the consensus of opinions?
Beckers, Albert ULg; Daly, Adrian ULg; Petrossians, Patrick ULg et al

in International Novartis Workshop - somatostatin and its natural and synthetic analogues - Update from basic to clinical aspects - Abstract book (2005)

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See detailDiagnosis of bovine brucellosis by skin test: conditions for the test and evaluation of its performance.
Saegerman, Claude ULg; Vo, T. K.; De Waele, L. et al

in Veterinary Record : Journal of the British Veterinary Association (1999), 145(8), 214-8

Brucellergene OCB (Rhone-Merieux) was used as an allergen to define the intrinsic parameters of a skin test and to compare its properties with serology for the diagnosis of bovine brucellosis. The skin ... [more ▼]

Brucellergene OCB (Rhone-Merieux) was used as an allergen to define the intrinsic parameters of a skin test and to compare its properties with serology for the diagnosis of bovine brucellosis. The skin test was also evaluated for its capacity to solve problems associated with false positive reactions in serological tests. The optimal reading delay for the skin test was 72 hours. The brucellosis allergic reaction was two to three times less intense than the tuberculosis allergic reaction. An increase of 1.1 mm or more in the skin thickness was therefore considered to be an adequate cut-off. The specificity calculated for 1192 brucellosis-free animals (including animals from brucellosis-free herds in which false positive serological reactions had been reported) was 99-83 per cent (95 per cent confidence interval [CI] 99-40 to 99-98 per cent). The sensitivity determined from 27 experimentally infected heifers ranged from 93 per cent (95 per cent CI 76 to 100 per cent) to 78 per cent (95 per cent CI 58 to 91 per cent) when measured respectively one and six months after the infection. Allergic reactions could be detected in vaccinated animals up to four-and-a-half years after the vaccination. On the other hand, no sensitisation was recorded in naive animals after up to eight monthly injections of the allergen. The skin test gave valuable information, in combination with the serological tests, in both acute and chronic brucellosis. The skin test discriminated brucellosis clearly from false positive serological reactions due to infections with Yersinia enterocolitica O9. [less ▲]

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See detailDiagnosis of brucellosis in livestock and wildlife
Godfroid, J.; Nielsen, K.; Saegerman, Claude ULg

in Croation Medical Journal (2010), 51(4), 296-305

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See detailDiagnosis of brucellosis in livestock and wildlife.
Godfroid, Jacques; Nielsen, Klaus; Saegerman, Claude ULg

in Croatian Medical Journal (2010), 51(4), 296-305

AIM: To describe and discuss the merits of various direct and indirect methods applied in vitro (mainly on blood or milk) or in vivo (allergic test) for the diagnosis of brucellosis in animals. METHODS ... [more ▼]

AIM: To describe and discuss the merits of various direct and indirect methods applied in vitro (mainly on blood or milk) or in vivo (allergic test) for the diagnosis of brucellosis in animals. METHODS: The recent literature on brucellosis diagnostic tests was reviewed. These diagnostic tests are applied with different goals, such as national screening, confirmatory diagnosis, certification, and international trade. The validation of such diagnostic tests is still an issue, particularly in wildlife. The choice of the testing strategy depends on the prevailing brucellosis epidemiological situation and the goal of testing. RESULTS: Measuring the kinetics of antibody production after Brucella spp. infection is essential for analyzing serological results correctly and may help to predict abortion. Indirect ELISAs help to discriminate 1) between false positive serological reactions and true brucellosis and 2) between vaccination and infection. Biotyping of Brucella spp. provides valuable epidemiological information that allows tracing an infection back to the sources in instances where several biotypes of a given Brucella species are circulating. Polymerase chain reaction and new molecular methods are likely to be used as routine typing and fingerprinting methods in the coming years. CONCLUSION: The diagnosis of brucellosis in livestock and wildlife is complex and serological results need to be carefully analyzed. The B. abortus S19 and B. melitensis Rev. 1 vaccines are the cornerstones of control programs in cattle and small ruminants, respectively. There is no vaccine available for pigs or for wildlife. In the absence of a human brucellosis vaccine, prevention of human brucellosis depends on the control of the disease in animals. [less ▲]

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See detailDiagnosis of canine sino-nasal aspergillosis: is quantification of Aspergillus DNA a useful technique?
Peeters, Dominique ULg; Peters, I. R.; Helps et al

in Proceedings of the 24th VCRS meeting (2006)

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See detailDiagnosis of cyst infection in patients with autosomal dominant polycystic kidney disease: attributes and limitations of the current modalities.
JOURET, François ULg; Lhommel, Renaud; Devuyst, Olivier et al

in Nephrology Dialysis Transplantation (2012), 27(10), 3746-51

Cyst infection is a diagnostic challenge in patients with autosomal dominant polycystic kidney disease (ADPKD) because of the lack of specific manifestations and limitations of conventional imaging ... [more ▼]

Cyst infection is a diagnostic challenge in patients with autosomal dominant polycystic kidney disease (ADPKD) because of the lack of specific manifestations and limitations of conventional imaging procedures. Still, recent clinical observations and series have highlighted common criteria for this condition. Cyst infection is diagnosed if confirmed by cyst fluid analysis showing bacteria and neutrophils, and as a probable diagnosis if all four of the following criteria are concomitantly met: temperature of >38 degrees C for >3 days, loin or liver tenderness, C-reactive protein plasma level of >5 mg/dL and no evidence for intracystic bleeding on computed tomography (CT). In addition, the elevation of serum carbohydrate antigen 19-9 (CA19-9) has been proposed as a biomarker for hepatic cyst infection. Positron-emission tomography after intravenous injection of 18-fluorodeoxyglucose, combined with CT, proved superior to radiological imaging techniques for the identification and localization of kidney and liver pyocyst. This review summarizes the attributes and limitations of these recent clinical, biological and imaging advances in the diagnosis of cyst infection in patients with ADPKD. [less ▲]

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See detailThe diagnosis of enzootic bovine leukosis.
Mammerickx, Marc; Portetelle, Daniel ULg; Burny, Arsène

in Comparative Immunology, Microbiology and Infectious Diseases (1985), 8

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See detailDiagnosis of HIV-1 in African couples : comparison of serology and PCR
Vaira, Dolorès ULg; Sondag, Danièle ULg; François-Gérard, C. et al

in Cinquième conférence internationale sur le SIDA : le défi scientifique et social (1989)

OBJECTIVE: Search for the rate of HIV-1 contamination among seronegative sexual partners of seropositive individuals. METHODS: Classical serological methods (EIA, WB) and PCR. SERIES: 36 heterosexual ... [more ▼]

OBJECTIVE: Search for the rate of HIV-1 contamination among seronegative sexual partners of seropositive individuals. METHODS: Classical serological methods (EIA, WB) and PCR. SERIES: 36 heterosexual couples from central Africa, accounting for a total of 73 persons: 13/37 seropositive women, 23/36 seropositive men. All couples were serologically discordant, i.e. one partner was seropositive. CONCLUSIONS: In such a population, particularly at risk of HIV contamination, the rate of false negative serological diagnosis reached 70%. [less ▲]

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See detailDiagnosis of lower airways dysfunction
Art, Tatiana ULg; Lekeux, Pierre ULg; Amory, Hélène ULg

in Proceedings of the 6th Annual Scientific Meeting of the European College of Veterinary Surgeons (1997)

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See detailDiagnosis of myxomatosis by an indirect immunoperoxidase test
Marlier, Didier ULg; Boucraut-baralon, Corine; Vindevogel, Henri ULg

in Vlaams Diergeneeskundig Tijdschrift (1999), 68

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See detailDiagnosis of obstructive sleep apnoea and hypopnoea syndrome based on automatic analysis of mandibular movements
Senny, Frédéric ULg; Destiné, Jacques ULg; Ansay, Pierre et al

in Proceedings of the 1st WASM Congress (2005, October)

Our study showed the potential of a surrogate of the oesophageal pressure, the jaw motion, and a dedicated automatic analysis to diagnose the obstructive sleep apnoea and hypopnoea syndrome (OSAHS ... [more ▼]

Our study showed the potential of a surrogate of the oesophageal pressure, the jaw motion, and a dedicated automatic analysis to diagnose the obstructive sleep apnoea and hypopnoea syndrome (OSAHS). Twentyfour patients were recorded in hospital settings and the jaw motion of fifteen of them was also recorded at home with an ambulatory device. The apnoea and hypopnoea index (AHI) of the gold standard, AHI_PSG, and the two AHI from the automatic analysis of the jaw motion, AHI_H (hospital) and AHI_A (ambulatory), were compared : AHI_PSG Vs AHI_H showed good correlation (r = 0.97) and under-estimation (slope p = 0.76). AHI_A Vs AHI_H revealed good reliability with r = 0.98 and slope p = 0.99. Finally, AHI_PSG Vs AHI_A showed very good accuracy of the diagnosis with sensitivity of 90% and specificity of 100%. [less ▲]

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See detailDiagnosis of osteoporosis without prevalent fractures: are we missing our main target?
Richy, F.; Reginster, Jean-Yves ULg

in Osteoporosis Action (2006), 1

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See detailDiagnosis of parathyroid carcinoma: potential role of PTH laboratory assays
CAVALIER, Etienne ULg

Conference (2012, September 08)

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See detailDiagnosis of Pathogens responsible of pre-and post-harvest rice diseases in Madagascar
Razanakoto Mamiharisoa, Lea; De Clerck, Caroline ULg; Parisi, Olivier ULg et al

Poster (2013)

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See detailDiagnosis of pharyngeal disorders in dogs: a retrospective study of 67 cases
Billen, Frédéric ULg; Day, M. J.; Clercx, Cécile ULg

in Journal of Small Animal Practice (2006), 47(3), 122-129

OBJECTIVES: To assess the frequency distribution of pharyngeal disorders and to compare clinical signs in diseases of the different pharyngeal areas. To review the investigation methods. METHODS: Medical ... [more ▼]

OBJECTIVES: To assess the frequency distribution of pharyngeal disorders and to compare clinical signs in diseases of the different pharyngeal areas. To review the investigation methods. METHODS: Medical records of 67 dogs presenting with abnormalities of the pharyngeal area were retrospectively reviewed and classified according to the anatomic area involved, i.e. the nasopharyngeal, oropharyngeal and laryngopharyngeal areas. Clinical signs, endoscopic findings and results of additional sampling were reviewed. RESULTS: Nasopharyngeal disorders were most frequently encountered (49 per cent), with choanal masses being the most frequent diagnosis (24 of 33), followed by laryngopharyngeal disorders (37.5 per cent) and oropharyngeal disorders (10.5 per cent). A rare condition, stenosis of the intrapharyngeal opening, was classified separately (3 per cent). An overall good correlation between matched cytology and histopathology samples was found. In all categories of diseases, clinical signs related to both the upper respiratory and digestive tracts were reported. CLINICAL SIGNIFICANCE: Pharyngeal disorders are more frequently localised in the nasopharyngeal area and include essentially choanal masses. The use of a flexible endoscope for retrograde rhinoscopy is essential for adequate investigation of the proximal nasopharyngeal area. Clinical signs do not allow differentiation of the pharyngeal disorder within the different pharyngeal areas. [less ▲]

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See detailDiagnosis of primary thyrotrophin-secreting microadenoma by 1.5 T MR.
Stadnik, T.; Stevenaert, Achille ULg; Beckers, Albert ULg et al

in European Journal of Radiology (1992), 14(1), 18-21

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See detailDiagnosis of Process Faults in Chemical Systems Using a Local Partial Least Squares Approach
Kruger, Uwe; Dimitriadis, Grigorios ULg

in AIChE Journal (2008), 54(10), 2581-2596

This article discusses the application of partial least squares (PLS) for monitoring complex chemical systems. In relation to existing work, this article proposes the integration of the statistical local ... [more ▼]

This article discusses the application of partial least squares (PLS) for monitoring complex chemical systems. In relation to existing work, this article proposes the integration of the statistical local approach into the PLS framework to monitor changes in the underlying model rather than analyzing the recorded input/output data directly. As discussed in the literature, monitoring changes in model parameters addresses the problems of nonstationary behavior and presents an analogy to model-based approaches. The benefits of the proposed technique are that (i) a detailed mechanistic plant model is not required, (ii) nonstationary process behavior does not produce false alarms, (iii) parameter changes can be non-Gaussian, (iv) Gaussian monitoring statistics can be established to simplify the monitoring task, and (v) fault magnitude and signatures can be estimated. This is demonstrated by a simulation example and the analysis of recorded data from two chemical processes. [less ▲]

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See detailDiagnosis of psoroptic sheep scab with an improved enzyme-linked immunosorbent assay.
Ochs, H.; Lonneux, J.; Losson, Bertrand ULg et al

in Veterinary Parasitology (2001), 96(3), 233-42

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of specific antibodies against crude Psoroptes antigen. The diagnostic sensitivity was 93.7% in 191 sheep with clinical signs ... [more ▼]

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of specific antibodies against crude Psoroptes antigen. The diagnostic sensitivity was 93.7% in 191 sheep with clinical signs associated with mange. These animals originated from 29 flocks in which psoroptic mites were detected. All of 59 sheep infested with Psoroptes ovis were seropositive. Additionally, in 49% of 70 clinically unaffected sheep originating from P. ovis-infested flocks, specific antibodies could be detected, suggesting that asymptomatic infestations can be diagnosed by serology. The specificity of the ELISA was 96.5% as determined with 254 sheep originating from 44 flocks without clinical mange. Cross-reactivity in a low range was detected with selected sera of sheep with clinical chorioptic or forage mite infestations. Four sheep seroconverted 2 weeks after experimental P. ovis infestation, i.e. 2 weeks before clinical signs became obvious. After successful doramectin treatment of 14 sheep with naturally acquired P. ovis infestation, the ELISA values declined slowly but remained positive in seven cases beyond 17 weeks. [less ▲]

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See detailDiagnosis of small bowel malabsorption syndromes in adults
Belaiche, Jacques ULg; Louis, Edouard ULg

in Acta Gastro-Enterologica Belgica (2006), 69(1, Jan-Mar), 31-37

Patients with malabsorption represent a small proportion of presentations with chronic diarrhea. In spite of some progress, the last twenty years were not very innovating in malabsorption investigations ... [more ▼]

Patients with malabsorption represent a small proportion of presentations with chronic diarrhea. In spite of some progress, the last twenty years were not very innovating in malabsorption investigations. Supporting history may direct investigations toward either the small bowel or pancreas. Serological testing for celiac disease will determine most cases without invasive investigation, but individuals suspected to have small bowel malabsorption, despite negative celiac serology, should have endoscopic distal duodenal biopsies taken to exclude other rare forms of small bowel enteropathy. This strategy has largely supplanted many older tests of small bowel function. [less ▲]

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See detailDiagnosis of the sediment transport in the Belgian Coastal Zone
Mercier, Christophe ULg; Delhez, Eric ULg

in Estuarine Coastal & Shelf Science (2007), 74(4), 670-683

Estimating the age of particles in marine environment constitutes an invaluable tool to understand the interactions between complex flows and sediment dynamics, particularly in highly energetic coastal ... [more ▼]

Estimating the age of particles in marine environment constitutes an invaluable tool to understand the interactions between complex flows and sediment dynamics, particularly in highly energetic coastal areas such as the Belgian Coastal Zone (Southern Bight in the North Sea). To this end, the Constituent Age and Residence time Theory-CART-introduced by Delhez, E.J.M., Campin, J.-M., Hirst, A.C., Deleersnijder, E. [1999a. Toward a general theory of the age in ocean modelling. Ocean Modelling 1, 17-27] for passive water constituents is extended to describe the sediment dynamics. It is then used in combination with a three-dimensional coupled hydrodynamic-sediment transport model to investigate sediment processes in the Belgian Coastal Zone focusing on two complementary aspects of the sediment dynamics: the internal sediment motion and redistribution within the Belgian coast; and the horizontal transport. (C) 2007 Elsevier Ltd. All rights reserved. [less ▲]

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