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See detailCoopératives et démocratie : un état des lieux de la question pour encourager la vitalité démocratique des coopératives
Rijpens, Julie ULg; Jonet, Christian; Mertens de Wilmars, Sybille ULg

in Van Gyes, Guy; De Spiegelaere, Stan (Eds.) L'entreprise de nous tous. Innover la participation des travailleurs en Belgique (2015)

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See detailCoopératives et démocratie participative
Mouchamps, Hugues ULg

Conference given outside the academic context (2013)

Detailed reference viewed: 31 (7 ULg)
See detailCooperativity between fibroblasts and melanoma cells during invasion
Siwek, Brigitte; Munaut, Carine ULg; De Pauw-Gillet, Marie-Claire ULg et al

Conference (1989)

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See detailCooperativity of peptidoglycan synthases active in bacterial cell elongation.
Banzhaf, Manuel; van den Berg van Saparoea, Bart; Terrak, Mohammed ULg et al

in Molecular Microbiology (2012), 85(1), 179-94

Growth of the bacterial cell wall peptidoglycan sacculus requires the co-ordinated activities of peptidoglycan synthases, hydrolases and cell morphogenesis proteins, but the details of these interactions ... [more ▼]

Growth of the bacterial cell wall peptidoglycan sacculus requires the co-ordinated activities of peptidoglycan synthases, hydrolases and cell morphogenesis proteins, but the details of these interactions are largely unknown. We now show that the Escherichia coli peptidoglycan glycosyltrasferase-transpeptidase PBP1A interacts with the cell elongation-specific transpeptidase PBP2 in vitro and in the cell. Cells lacking PBP1A are thinner and initiate cell division later in the cell cycle. PBP1A localizes mainly to the cylindrical wall of the cell, supporting its role in cell elongation. Our in vitro peptidoglycan synthesis assays provide novel insights into the cooperativity of peptidoglycan synthases with different activities. PBP2 stimulates the glycosyltransferase activity of PBP1A, and PBP1A and PBP2 cooperate to attach newly synthesized peptidoglycan to sacculi. PBP2 has peptidoglycan transpeptidase activity in the presence of active PBP1A. Our data also provide a possible explanation for the depletion of lipid II precursors in penicillin-treated cells. [less ▲]

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See detailCooperativity of the glucocorticoid receptor and the CACCC-box binding factor.
Schule, Roland; Muller, Marc ULg; Otsuka-Murakami, Hidetsuka et al

in Nature (1988), 332(6159), 87-90

Glucocorticoid receptor binding sites (GRE) are often tightly clustered with other transcription factor binding sequences. Examples of this occur upstream of the genes for chicken lysozyme and human ... [more ▼]

Glucocorticoid receptor binding sites (GRE) are often tightly clustered with other transcription factor binding sequences. Examples of this occur upstream of the genes for chicken lysozyme and human metallothionein IIA (ref. 3), in several retroviral LTRs and upstream of the rat tryptophan oxygenase (TO) gene. In the TO gene, sequences immediately upstream of a glucocorticoid receptor binding site are required for steroid induction and contain a CACCC-box identical to that found in the beta globin gene. Here we demonstrate specific binding to this TO-CACCC element and show that it will also act cooperatively with a MMTV glucocorticoid receptor binding site. The response to dexamethasone is independent of the order and relative orientation of these elements but does depend on their precise spacing. Optimal induction occurs at a periodicity of approximately 10 base pairs (bp) indicating a requirement for stereospecific alignment. Binding to the CACCC box, however, is not affected by its distance from the glucocorticoid receptor site. We conclude that the observed cooperativity is mediated by protein:protein interactions and does not depend on cooperative DNA binding. [less ▲]

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See detailCoordinate Enhancement of Gelatinase a Mrna and Activity Levels in Human Fibroblasts in Response to Breast-Adenocarcinoma Cells
Noël, Agnès ULg; Polette, M.; Lewalle, J. M. et al

in International Journal of Cancer = Journal International du Cancer (1994), 56(3), 331-6

Gelatinases/type-IV collagenases are metalloproteinases involved in some carcinoma invasion and metastatic processes. The exact cellular source of the 72-kDa gelatinase A is controversial. We have ... [more ▼]

Gelatinases/type-IV collagenases are metalloproteinases involved in some carcinoma invasion and metastatic processes. The exact cellular source of the 72-kDa gelatinase A is controversial. We have analyzed the expression of mRNA coding for gelatinase A in vivo by in situ hybridization on breast-cancer tissues. The mRNA for gelatinase A was present in fibroblasts. We have therefore evaluated the gelatinase-A activity in vitro, in co-cultures of different breast adenocarcinoma cell lines and human fibroblasts. In monoculture, none of the tumor cells tested produced detectable amounts of gelatinase A. The gelatinase-A activity was enhanced in cultures of fibroblasts maintained in the presence of MDA-MB 231 or SKBR3 cells, or their conditioned medium. This increased enzymatic activity was evidenced both in the culture medium and in the membrane fraction and was paralleled by enhancement of the steady-state levels of mRNA. These results are an in vitro demonstration of a regulation of fibroblasts gelatinase-A production by soluble factors secreted by breast-tumor cells. [less ▲]

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See detailCoordinate rotations
Heinesch, Bernard ULg

Conference (2006)

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See detailCoordinate transformation techniques for efficient model reduction in flexible multibody dynamics
Heirman, Gert H.K; Bruls, Olivier ULg; Sas, Paul et al

in Proceedings of ISMA 2008 (2008, September)

Computational efficiency is important for all numerical simulation tools. For real-time and faster-than-realtime applications, which rely on a strong interaction between simulation results and other ... [more ▼]

Computational efficiency is important for all numerical simulation tools. For real-time and faster-than-realtime applications, which rely on a strong interaction between simulation results and other subsystems, it is vital. This paper proposes a theoretical framework for coordinate transformations to recast the differential-algebraic system equations of a flexible mechanism into a simpler set of equations, which is cheaper to solve. Desirable properties of the coordinate transformation to minimize the computational burden of the simulation are discussed, as well as some assumptions that can be made for further simplification. A methodology to make practical use of coordinate transformation techniques to speed up simulation speed for real-time and faster- than-real-time applications is presented. [less ▲]

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See detailCoordinated and dissociated effects of testosterone on singing behavior and song control nuclei in canaries (Serinus canaria)
Sartor, Jennifer J.; Balthazart, Jacques ULg; Ball, Gregory F.

in Hormones & Behavior (2005), 47(4), 467-476

Temperate zone songbirds that breed seasonally exhibit pronounced differences in reproductive behaviors including song inside and outside the breeding season. Springlike long daylengths are associated ... [more ▼]

Temperate zone songbirds that breed seasonally exhibit pronounced differences in reproductive behaviors including song inside and outside the breeding season. Springlike long daylengths are associated with increases in plasma testosterone (T) concentrations, as well as with increases in singing and in the volume of several brain nuclei known to control this behavior. The mechanisms whereby T can induce changes in behavior and brain, and whether or not these effects are differentially regulated, have recently begun to be examined, as has the question of the relative contributions of T and its androgenic and estrogenic metabolites to the regulation of this seasonal behavioral and neural plasticity. In this experiment, we examined the effects of T, 5 alpha-dihydrotestosterone, or 17 beta-estradiol treatment on castrated male canaries housed on short days and compared neural and behavioral effects in these males to similarly-housed males given only blank implants. We observed that only T treatment was effective in eliciting significant increases in singing behavior after 11 days of hormone exposure. In addition, T alone was effective in increasing the volume of a key song production nucleus, HVC. However, at this time, none of the steroids had any effects on the volumes of two other song control nuclei, Area X of the medial striatum and the robust nucleus of the arcopallium (RA), that are efferent targets of HVC, known to be regulated by androgen in canaries and also to play a role in the control of adult song. T can thus enhance singing well before concomitant androgen-induced changes in the song control system are complete. (c) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailThe Coordinated Climate-Crop Modeling Project (C3MP)
Ruane, A.; McDermid, S.; Hudson, N. et al

Conference (2013, October)

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See detailThe Coordinated Climate-Crop Modeling Project
McDermid, S.; Ruane, A.; Hudson, N. et al

Conference (2013, November)

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See detailA coordinated coastal ocean observing and modeling system for the West Florida Continental Shelf
Weisberg, R. H.; Barth, Alexander ULg; Alvera Azcarate, Aïda ULg et al

in Harmful Algae (2009), 8(4), 585-597

The evolution of harmful algal blooms, while dependent upon complex biological interactions, is equally dependent upon the ocean circulation since the circulation provides the basis for the biological ... [more ▼]

The evolution of harmful algal blooms, while dependent upon complex biological interactions, is equally dependent upon the ocean circulation since the circulation provides the basis for the biological interactions by uniting nutrients with light and distributing water properties. For the coastal ocean, the circulation and the resultant water properties, in turn, depend on interactions between both the continental shelf and the deep-ocean and the continental shelf and the estuaries since the deep-ocean and the estuaries are primary nutrient sources. Here we consider a coordinated program of observations and models for the West Florida Continental Shelf (WFS) intended to provide a supportive framework for K. brevis red-tide prediction as well as for other coastal ocean matters of societal concern. Predicated on lessons learned, the goal is to achieve a system complete enough to support data assimilative modeling and prediction. Examples of the observations and models are presented and application is made to aspects of the 2005 red-tide. From an observational perspective, no single set of measurements is adequate. Required are a broad mix of sensors and sensor delivery systems capable of describing the three-dimensional structure of the velocity and density fields. Similarly, models must be complete enough to include the relevant physical processes, and data assimilation provides the integrative framework for maximizing the joint utility of the observations and models. While we are still in the exploratory stages of development, the lessons learned and application examples may be useful to similar programs under development elsewhere. One scientific finding is that the key to understanding K. brevis red-tide on the WFS lies not at the surface, but at depth [less ▲]

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See detailCoordinated measurements of auroral processes at Saturn from the Cassini spacecraft and HST
Mitchell, D. G.; Kurth, William; Hospodarsky, G. B. et al

Conference (2008, December 01)

One of the primary Cassini mission objectives at Saturn is to characterize Saturn's aurora-its spatial morphology, associated particle energization, radio wave generation, and magnetospheric currents ... [more ▼]

One of the primary Cassini mission objectives at Saturn is to characterize Saturn's aurora-its spatial morphology, associated particle energization, radio wave generation, and magnetospheric currents, relationship with solar wind pressure and magnetic field, and its large scale mapping to the magnetosphere. By design, the Cassini orbital tour included high inclination and low periapsis orbits late in the prime mission specifically to address many of these topics. In this presentation, we will provide a snapshot of the current state of our investigation into the relationship between magnetospheric measurements of particles and fields, and the aurora. For in situ data, we will show measurements of upward traveling light ion conics (~30 keV to 200 keV), often accompanied by electron beams (<20 keV to ~1 MeV) and enhanced broadband noise (10 Hz to a few kHz), throughout the outer magnetosphere on field lines that nominally map from well into the polar cap (dipole L > 50) to well into the closed field region (dipole L < 10). Sometimes the particle phenomena and the broadband noise occur in pulses of roughly five-minute duration, separated by tens of minutes. At other times they are relatively steady over an hour or more. Magnetic signatures associated with some of the pulsed events are consistent with field aligned current structures. Correlative observations of solar wind (Cassini) and aurora (HST) have established a strong relationship between solar wind pressure and auroral activity (brightness) (Crary et al., Nature, 2005; Clarke et al., JGR, 2008). A similar correspondence between bright auroral arcs and ring current ion acceleration will be shown here. So while some auroral forms seem to be associated with the open/closed field boundary (i.e. in the cusp-Bunce et al., JGR, 2008), we also demonstrate that under some magnetospheric conditions for which protons and oxygen ions are accelerated once per Saturn magnetosphere rotation at a preferred local time between midnight and dawn, simultaneous auroral observations by the HST reveal a close correlation between these dynamical magnetospheric events and dawn-side transient auroral brightenings. Likewise, many of the recurrent energetic neutral atom enhancements coincide closely with bursts of Saturn kilometric radiation, again suggesting a linkage with high latitude auroral processes. Finally, we will show some intriguing results of auroral movie sequences from the Cassini UVIS instrument with corresponding ring current movies from the Magnetospheric Imaging Instrument Ion and Neutral Camera (MIMI/INCA). [less ▲]

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See detailCoordinated monitoring of the eccentric O-star binary Iota Orionis: optical spectroscopy and photometry
Marchenko, Sergey V; Rauw, Grégor ULg; Antokhina, Eleonora A et al

in Monthly Notices of the Royal Astronomical Society (2000), 317

With the objective of investigating the wind-wind collision phenomenon and supporting contemporaneous X-ray observations, we have organized a large-scale, coordinated optical monitoring campaign of the ... [more ▼]

With the objective of investigating the wind-wind collision phenomenon and supporting contemporaneous X-ray observations, we have organized a large-scale, coordinated optical monitoring campaign of the massive, highly eccentric O9III+B1III binary Iota Orionis. Successfully separating the spectra of the components, we refine the orbital elements and confirm the rapid apsidal motion in the system. We also see strong interaction between the components during periastron passage and detect phase-locked variability in the spectrum of the secondary star. However, we find no unambiguous signs of the bow shock crashing on the surface of the secondary, despite the predictions of hydrodynamic simulations. Combining all available photometric data, we find rapid, phase-locked variations and model them numerically, thus restricting the orbital inclination to 50°<~i<~70°. [less ▲]

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See detailCoordinated monitoring of the eccentric O-star binary Iota Orionis: the X-ray analysis
Pittard, Julian M; Stevens, Ian R; Corcoran, Michael F et al

in Monthly Notices of the Royal Astronomical Society (2000), 319

We analyse two ASCA observations of the highly eccentric O9 III+B1 III binary Iota Orionis obtained at periastron and apastron. Based on the assumption of a strong colliding-wind shock between the stellar ... [more ▼]

We analyse two ASCA observations of the highly eccentric O9 III+B1 III binary Iota Orionis obtained at periastron and apastron. Based on the assumption of a strong colliding-wind shock between the stellar components, we expected to see significant variation in the X-ray emission between these phases. The observations proved otherwise: the X-ray luminosities and spectral distributions were remarkably similar. The only noteworthy feature in the X-ray data was the hint of a proximity effect during periastron passage. Although this `flare' is of relatively low significance, it is supported by the notable proximity effects seen in the optical, and the phasing of the X-ray and optical events is in very good agreement. However, other interpretations are also possible. In view of the degradation of the SIS instrument and source contamination in the GIS data we discuss the accuracy of these results, and also analyse archival ROSAT observations. We investigate why we do not see a clear colliding-wind signature. A simple model shows that the wind attenuation to the expected position of the shock apex is negligible throughout the orbit, which poses the puzzling question of why the expected 1/D variation (i.e. a factor of 7.5) in the intrinsic luminosity is not seen in the data. Two scenarios are proposed: either the colliding-wind emission is unexpectedly weak such that intrinsic shocks in the winds dominate the emission, or, alternatively, the emission observed is colliding-wind emission but in a more complex form than we would naively expect. Complex hydrodynamical models are then analysed. Despite strongly phase-variable emission from the models, both are consistent with the observations. We find that if the mass-loss rates of the stars are low then intrinsic wind shocks could dominate the emission. However, when we assume higher mass-loss rates of the stars, we find that the observed emission could also be consistent with a purely colliding-wind origin. A summary of the strengths and weaknesses of each interpretation is presented. To distinguish between the different models X-ray observations with improved phase coverage will be necessary. [less ▲]

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See detailCoordinated motion design on Lie groups
Sarlette, Alain ULg; Bonnabel, Silvere; Sepulchre, Rodolphe ULg

in IEEE Transactions on Automatic Control (2010), 55(5), 1047-1058

The present paper proposes a unified geometric framework for coordinated motion on Lie groups. It first gives a general problem formulation and analyzes ensuing conditions for coordinated motion. Then, it ... [more ▼]

The present paper proposes a unified geometric framework for coordinated motion on Lie groups. It first gives a general problem formulation and analyzes ensuing conditions for coordinated motion. Then, it introduces a precise method to design control laws in fully actuated and underactuated settings with simple integrator dynamics. It thereby shows that coordination can be studied in a systematic way once the Lie group geometry of the configuration space is well characterized. Applying the proposed general methodology to particular examples allows to retrieve control laws that have been proposed in the literature on intuitive grounds. A link with Brockett's double bracket flows is also made. The concepts are illustrated on SO(3) , SE(2) and SE(3). [less ▲]

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See detailCoordinated primary frequency control among non-synchronous systems connected by a multi-terminal high-voltage direct current grid
Dai, Jing; Phulpin, Yannick; Sarlette, Alain et al

in IET Generation, Transmission & Distribution (2012), 6(2), 99-108

The authors consider a power system composed of several non-synchronous AC areas connected by a multiterminal high-voltage direct current (HVDC) grid. In this context, the authors propose a distributed ... [more ▼]

The authors consider a power system composed of several non-synchronous AC areas connected by a multiterminal high-voltage direct current (HVDC) grid. In this context, the authors propose a distributed control scheme that modifies the power injections from the different AC areas into the DC grid so as to make the system collectively react to load imbalances. This collective reaction allows each individual AC area to downscale its primary reserves. The scheme is inspired by algorithms for the consensus problem extensively studied by the control theory community. It modifies the power injections based on frequency deviations of the AC areas so as to make them stay close to each other. A stability analysis of the closed-loop system is reported as well as simulation results on a benchmark power system with five AC areas. These results show that with proper tuning, the control scheme makes the frequency deviations converge rapidly to a common value following a load imbalance in an area. [less ▲]

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See detailCoordinated regulation of procollagens I and III and their post-translational enzymes by dissipation of mechanical tension in human dermal fibroblasts.
Lambert, Charles ULg; Colige, Alain ULg; Lapiere, C. M. et al

in European Journal of Cell Biology (2001), 80(7), 479-85

Mechanical tension governs fibroblast proliferation and survival and the homeostasis of the extracellular matrix to adapt its resistance to the mechanical requirements of the organs. To consolidate this ... [more ▼]

Mechanical tension governs fibroblast proliferation and survival and the homeostasis of the extracellular matrix to adapt its resistance to the mechanical requirements of the organs. To consolidate this view, we analysed the effect of tension release on the expression of molecules involved in the architecture and stabilisation of the collagen fibres, namely the procollagens type I and III, the amino- and carboxy-procollagen peptidases (N-pCP and C-pCP) and lysyl oxidase. Cells were cultured in conditions of high mechanical stress in monolayer on a collagen coat and under reduced tension by disruption of the cytoskeleton upon treatment with cytochalasin D in monolayer on a collagen coat or by integrin-mediated stress relaxation in a freely retracting collagen gel. The mRNAs were measured by quantitative RT-PCR monitored by simultaneous reverse-transcription and amplification of an original internal standard. Tension relaxation resulted in a decreased expression of the procollagens type I and III, of the two expressed forms of C-pCP, of the two forms of N-pCP and of lysyl oxidase. Type III collagen, known to control diameter of the fibres, was less down-regulated than type I collagen. Interestingly, the expression of the two alternatively spliced forms of the N-pCP was dissimilarly regulated. These data suggest that mechanical tension may modulate the stiffness of the extracellular matrix by controlling not only the level of expression of its fibrillar constituents but also that of the enzymes participating in their extracellular processing and mechanical stabilisation. [less ▲]

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See detailCOORDINATED VOLTAGE CONTROL OF DISTRIBUTION NETWORKS HOSTING DISPERSED GENERATION
Van Cutsem, Thierry ULg; Valverde, Gustavo ULg

in Proc. 22nd International conference on Electricity Distribution (2013, June)

This paper presents a centralized control scheme to regulate distribution network voltages in the presence of dispersed generation. The algorithm resorts to model predictive control to smoothly bring ... [more ▼]

This paper presents a centralized control scheme to regulate distribution network voltages in the presence of dispersed generation. The algorithm resorts to model predictive control to smoothly bring unsatisfactory voltages inside the desired range of values. Using a sensitivity model, the controller calculates optimal power output changes of distributed generators to correct the network voltages, giving priority to reactive over active power. Simulations results are presented on a 32-bus test system and three variants of the optimization problem are compared. [less ▲]

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