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See detailDarwin---an experimental astronomy mission to search for extrasolar planets
Cockell, Charles S; Herbst, Tom; Léger, Alain et al

in Experimental Astronomy (2009), 23

As a response to ESA call for mission concepts for its Cosmic Vision 2015--2025 plan, we propose a mission called Darwin. Its primary goal is the study of terrestrial extrasolar planets and the search for ... [more ▼]

As a response to ESA call for mission concepts for its Cosmic Vision 2015--2025 plan, we propose a mission called Darwin. Its primary goal is the study of terrestrial extrasolar planets and the search for life on them. In this paper, we describe different characteristics of the instrument. [less ▲]

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See detailDarwin-A Mission to Detect and Search for Life on Extrasolar Planets
Cockell, C. S.; Léger, A.; Fridlund, M. et al

in Astrobiology (2009), 9(1)

The discovery of extrasolar planets is one of the greatest achievements of modern astronomy. The detection of planets that vary widely in mass demonstrates that extrasolar planets of low mass exist. In ... [more ▼]

The discovery of extrasolar planets is one of the greatest achievements of modern astronomy. The detection of planets that vary widely in mass demonstrates that extrasolar planets of low mass exist. In this paper, we describe a mission, called Darwin, whose primary goal is the search for, and characterization of, terrestrial extrasolar planets and the search for life. Accomplishing the mission objectives will require collaborative science across disciplines, including astrophysics, planetary sciences, chemistry, and microbiology. Darwin is designed to detect rocky planets similar to Earth and perform spectroscopic analysis at mid-infrared wavelengths (6-20 mum), where an advantageous contrast ratio between star and planet occurs. The baseline mission is projected to last 5 years and consists of approximately 200 individual target stars. Among these, 25-50 planetary systems can be studied spectroscopically, which will include the search for gases such as CO[SUB]2[/SUB], H[SUB]2[/SUB]O, CH[SUB]4[/SUB], and O[SUB]3[/SUB]. Many of the key technologies required for the construction of Darwin have already been demonstrated, and the remainder are estimated to be mature in the near future. Darwin is a mission that will ignite intense interest in both the research community and the wider public. [less ▲]

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See detailThe Darwin-GENIE Experiment: An ESA-ESO Partnership
Gondoin, Ph; Absil, Olivier ULg; Erd, C. et al

in Sembach, K. R.; Blades, J. C.; Illingworth, G. D. (Eds.) et al Hubble's Science Legacy: Future Optical/Ultraviolet Astronomy from Space (2003)

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See detailDarwin-GENIE: a nulling instrument at the VLTI
Gondoin, Philippe A; Absil, Olivier ULg; den Hartog, Roland H et al

in Traub, Wesley (Ed.) New Frontiers in Stellar Interferometry (2004, October 01)

Darwin is one of the most challenging space projects ever considered by the European Space Agency (ESA). Its principal objectives are to detect Earth-like planets around nearby stars and to characterise ... [more ▼]

Darwin is one of the most challenging space projects ever considered by the European Space Agency (ESA). Its principal objectives are to detect Earth-like planets around nearby stars and to characterise their atmospheres. Darwin is conceived as a space "nulling interferometer" which makes use of on-axis destructive interferences to extinguish the stellar light while keeping the off-axis signal of the orbiting planet. Within the frame of the Darwin program, the European Space Agency (ESA) and the European Southern Observatory (ESO) intend to build a ground-based technology demonstrator called GENIE (Ground based European Nulling Interferometry Experiment). Such a ground-based demonstrator built around the Very Large Telescope Interferometer (VLTI) in Paranal will test some of the key technologies required for the Darwin Infrared Space Interferometer. It will demonstrate that nulling interferometry can be achieved in a broad mid-IR band as a precursor to the next phase of the Darwin program. The instrument will operate in the L' band around 3.8 mum, where the thermal emission from the telescopes and the atmosphere is reduced. GENIE will be able to operate in two different configurations, i.e. either as a single Bracewell nulling interferometer or as a double-Bracewell nulling interferometer with an internal modulation scheme. [less ▲]

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See detailDarwin: required performance (invited)
Absil, Olivier ULg

Scientific conference (2007, December 06)

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See detailLe darwinisme peut-il tout expliquer ?
Baurain, Denis ULg

Conference given outside the academic context (2005)

Vus d'Europe, les procès opposant les farouches défenseurs du darwinisme à leurs pugnaces détracteurs ont de quoi faire sourire. Certes, il n'y a pas qu'aux Etats-Unis que l'on puisse encore trouver des ... [more ▼]

Vus d'Europe, les procès opposant les farouches défenseurs du darwinisme à leurs pugnaces détracteurs ont de quoi faire sourire. Certes, il n'y a pas qu'aux Etats-Unis que l'on puisse encore trouver des Chrétiens fondamentalistes persuadés que Dieu a créé la Terre en six jours. En revanche, aucun gouvernement de nos contrées n'aurait l'idée saugrenue de faire interdire l'enseignement de la théorie de l'évolution dans nos écoles, ni même de l'autoriser à la condition expresse de la traiter sur le même pied que le créationnisme inspiré d'une lecture littérale de la Genèse. Cela dit, croire que le refus de l'évolution par "sélection naturelle des mutations favorables" se limite aux couches populaires de l'Amérique conservatrice serait inexact. En réalité, les plus acharnés des tenants du créationnisme pur et dur -- ou de son avatar à peine plus subtil, l'Intelligent Design -- sont généralement des intellectuels, voire dans certains cas des biologistes qui ont renoncé à toute carrière dans l'orthodoxie académique. Faut-il n'y voir qu'aveuglement religieux ? Sans doute, mais pas seulement... Originellement proposée en 1859, la théorie de l'évolution de Charles Darwin a profondément bouleversé la science et la société toute entière. Débarrassé de ses relents lamarckiens par August Weismann entre 1883 et 1888, le darwinisme, désormais qualifié de "néo-", s'est enrichi de la génétique de Gregor Mendel pour donner naissance en 1937, sous l'impulsion de Theodosius Dobzhansky, à la théorie synthétique de l'évolution. C'est dans cette incarnation "moderne" qu'il est devenu l'unique paradigme de la biologie contemporaine. Pourtant, loin des feux de la rampe, le couple infernal mutation/sélection ne satisfait pas tous les spécialistes. A quel point sa toute puissance peut-elle être mise en doute ? Dispose-t-on réellement de preuves de son efficacité, ou même tout simplement de son existence ? La diversité de la Vie sur Terre peut-elle s'expliquer par un principe aussi naïvement libéral ? C'est à ces questions et à quelques autres que nous tenterons de répondre au cours de cette conférence-débat, tout en tâchant de rester prudemment en dehors de toute considération métaphysique. Docteur en Sciences (Génétique Moléculaire Végétale), Denis BAURAIN est bioinformaticien à l'Université de Liège. Financées par le FNRS, ses recherches portent essentiellement sur l'histoire évolutive des premières cellules à noyau telle qu'on peut l'inférer à partir des séquences de gènes. [less ▲]

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See detailDas Leben der Anderen
Hamers, Jérémy ULg

Conference (2008, December 11)

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See detailDAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment
Cruyssen, B. V.; Van Looy, S.; Wyns, B. et al

in Arthritis Research & Therapy (2005), 7(5), 1063-1071

This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3 mg/kg ... [more ▼]

This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3 mg/kg+ methotrexate (MTX)) at weeks 0, 2, 6 and every 8 weeks thereafter. At week 22, 474 patients were still in follow-up, of whom 102 (21.5%), who were not optimally responding to treatment, received a dose increase from week 30 onward. We aimed to build a model to discriminate the decision to give a dose increase. This decision was based on the treating rheumatologist's clinical judgment and therefore can be considered as a clinical measure of insufficient response. Different single and composite measures at weeks 0, 6, 14 and 22, and their differences over time were taken into account for the model building. Ranking of the continuous variables based on areas under the curve of receiver-operating characteristic ( ROC) curve analysis, displayed the momentary DAS28 Disease Activity Score including a 28-joint count) as the most important discriminating variable. Subsequently, we proved that the response scores and the changes over time were less important than the momentary evaluations to discriminate the physician's decision. The final model we thus obtained was a model with only slightly better discriminative characteristics than the DAS28. Finally, we fitted a discriminant function using the single variables of the DAS28. This displayed similar scores and coefficients as the DAS28. In conclusion, we evaluated different variables and models to discriminate the treating rheumatologist's decision to increase the dose of infliximab (+MTX), which indicates an insufficient response to infliximab at 3 mg/kg in patients with RA. We proved that the momentary DAS28 score correlates best with this decision and demonstrated the robustness of the score and the coefficients of the DAS28 in a cohort of RA patients under infliximab therapy. [less ▲]

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See detailDashboard aimed at decision-makers and citizens in place managmenent, within SD principles
De Graef, Sarai; Dalimier, Isabelle; Ericx, Michel et al

Report (2009)

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See detailThe dashundergaps package
Merciadri, Luca ULg

Computer development (2009)

This is the manual of the dashundergaps package that I wrote. Briefly, this package aims at helping the LaTeX user at underlining a given set of words by either a line (using \underline{text}), dots ... [more ▼]

This is the manual of the dashundergaps package that I wrote. Briefly, this package aims at helping the LaTeX user at underlining a given set of words by either a line (using \underline{text}), dots (using \dotuline{text}) or even a dashed line (using \dashuline{text}). Various options were implemented for this. This can be used in conjunction with the phantomtext option, which allows the user to write a text with gaps, e.g. for a completion by students. These gaps can be completed with the real input using the teachernotes option. Please note that this is a really basic package. For more info on it, please look at the manual in the tarball. [less ▲]

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See detail« ... dass wir ihn nicht mehr sehen würden »: Absence et représentation d'un combattant armé (Farocki, Conradt, Sami)
Hamers, Jérémy ULg

Conference (2012, February 02)

La plupart des documentaires réalisés sur ou dans l’entourage de groupes terroristes d’extrême gauche allemand dans les années septante fondent leur approche sur une confusion délibérée entre militance et ... [more ▼]

La plupart des documentaires réalisés sur ou dans l’entourage de groupes terroristes d’extrême gauche allemand dans les années septante fondent leur approche sur une confusion délibérée entre militance et contrinformation. Ces films relayent et adaptent une conception, critiquée dès 1969 par Harun Farocki (Nicht löschbares Feuer), d’un outil audiovisuel strictement fonctionnel tel que le défend Holger Meins notamment : « Car le travail cinématographique socialiste doit être partie du travail politique. Et le travail cinématographique socialiste ne peut être réalisé sans la praxis du travail politique » (Meins/Lukasik/Straschek, 1968). Outre le célèbre film collectif Deutschland im Herbst (Kluge/Schlöndorff/Reitz/Fassbinder e.a., 1977), deux documentaires notamment font exception à cette tendance générale : Es stirbt allerdings ein Jeder de Renate Sami (1975) et Über Holger Meins de Gerd Conradt et Hartmut Jahn (1975-1982 ; ici dans sa version inédite et inachevée de 1978). Se focalisant tous deux sur le sort d’une figure absente, l’étudiant en cinéma Holger Meins devenu terroriste (RAF), ces films tournent le dos à une conception fonctionnelle de la pratique cinématographique défendue d’abord par certains piliers de la première promotion de la DFFB dès 1966. Ils proposent de la sorte une nouvelle approche des rapports problématiques entre militance et création, qui ne dédouble plus l’esthétique médiatique contre laquelle les vidéos et films indépendants voulaient se dresser. [less ▲]

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See detail‘… dat dit alles waar is’. Over De nacht der Girondijnen
Spinoy, Erik ULg

in Nieuwzuid (2007), 7(27), 4-15

This article rereads the novella De nacht van de Girondijnen by the Jewish-Dutch writer and historian Jacques Presser. This text is often considered to be a failed work of literature. This article avers ... [more ▼]

This article rereads the novella De nacht van de Girondijnen by the Jewish-Dutch writer and historian Jacques Presser. This text is often considered to be a failed work of literature. This article avers that this so-called failure in fact bears witness to Presser's traumatizing experience of the Shoah. [less ▲]

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See detailData adjudication
Adams, R.; Rust, K.; Monseur, Christian ULg

in Adams, R.; Wu, M. (Eds.) PISA 2000 : technical report (2002)

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See detailData analysis for linkage studies
Lathrop, M.; Cartwright, P.; Wright, S. et al

in Schook, L. B.; Lewin; McLaren (Eds.) Gene Mapping: strategies, techniques and applications (1991)

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See detailData Analysis Manual : sas second edition
Monseur, Christian ULg; OECD

Book published by OECD (2009)

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See detailData assimilation as a tool for upscaling
Vandenbulcke, Luc ULg; Barth, Alexander ULg; Ben Bouallegue, Z. et al

Conference (2006, April)

In ocean and atmospheric sciences, grid nesting is a common procedure in order to achieve (very) high resolution model outputs in regions of particular interest, at an acceptable computational cost ... [more ▼]

In ocean and atmospheric sciences, grid nesting is a common procedure in order to achieve (very) high resolution model outputs in regions of particular interest, at an acceptable computational cost. Nesting of grids can be passive (one-way nesting) or active (two-way nesting, with feedback from the high resolution to the low resolution grid). The benefits of active nesting have been shown multiple times in the litterature (see e.g. [1]). The positive effect of the feedback is visible inside the nested grid, but also outside of it, as corrections are advected with the flow. It must be noted however that in many operationnal implementations, only passive nesting is used, usually because active nesting requires too much data exchange between models, which should then wait for each other during their run. Data assimilation techniques are also widespread in oceanic and atmospheric models. They are usually applied in order to merge observations in models, but also e.g. to merge different outputs from ensemble runs of a model, to merge outputs from different models, or to replace downscaling between nested grids (see [3]). In our work, we present an alternative to active nesting (for implementations currently using passive nesting). First, the low-resolution model is run, followed by the local model. Afterwards, the low-resolution model is run once more, assimilating outputs from the local model as pseudo-data. The benefits of this approach over simple passive nesting are shown using a twin experiment. The GHER model (see [2]) is configured with a 0.25 resolution of the Mediterranean Sea, and with a 0.05 resoluion of the North-Western part; a twin experiment is then set. The reference run uses full two-way nesting, another run uses one-way nesting, and in a third run the assimilation procedure described above is implemented.Conclusions from this experiment are that our "upscaling" has positive impacts on the forecasts, provided a fair amount of EOFs is used during (reduced-rank) assimilation cycles. Finally, the set-up of ongoing work to implement our upscaling procedure in a realistic, operationnal system (the MFS system) is presented. [less ▲]

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See detailData Assimilation in a Nested Model of the Gulf of Lions
Vandenbulcke, Luc ULg; Barth, Alexander ULg; Ben Bouallegue, Z. et al

Conference (2004)

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See detailData assimilation in nested-grid models
Vandenbulcke, Luc ULg; Barth, Alexander ULg; Ben Bouallegue, Z. et al

Conference (2004, May)

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