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Peer Reviewed
See detailDelivering bad news to customers: The role of employee emotional and technical competences
Delcourt, Cécile ULg; Van Riel, Allard ULg; van Birgelen, Marcel et al

Conference (2011, July)

Detailed reference viewed: 27 (6 ULg)
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See detailDelivery Guarantees In Predictable Disruption Tolerant Networks
François, Jean-Marc; Leduc, Guy ULg

in Lecture Notes in Computer Science (2007, May), 4479

This article studies disruption tolerant networks (DTNs) where each node knows the probabilistic distribution of contacts with other nodes. It proposes a framework that allows one to formalize the ... [more ▼]

This article studies disruption tolerant networks (DTNs) where each node knows the probabilistic distribution of contacts with other nodes. It proposes a framework that allows one to formalize the behaviour of such a network. It generalizes extreme cases that have been studied before where either (a) nodes only know their contact frequency with each other or (b) they have a perfect knowledge of who meets who and when. This paper then gives an example of how this framework can be used; it shows how one can find a packet forwarding algorithm optimized to meet the delay/bandwidth consumption trade-off: packets are duplicated so as to (statistically) guarantee a given delay or delivery probability, but not too much so as to reduce the bandwidth, energy, and memory consumption. [less ▲]

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See detailDelivery of granulocyte-macrophage colony-stimulating factor in bioadhesive hydrogel stimulates migration of dendritic cells in models human papillomavirus-associated (pre)neoplastic epithelial lesions
Hubert, Pascale ULg; Evrard, Brigitte ULg; Maillard, Catherine ULg et al

in Antimicrobial Agents and Chemotherapy (2004), 48(11), 4342-4348

Because of the central role of dendritic cells and/or Langerhans cells(DC/LC) in the induction of cellular immune responses, pharmacological agents that modulate the recruitment of these cells might have ... [more ▼]

Because of the central role of dendritic cells and/or Langerhans cells(DC/LC) in the induction of cellular immune responses, pharmacological agents that modulate the recruitment of these cells might have a clinical interest. The present study was designed to evaluate the capacity of several pharmaceutical formulations to topically deliver granulocyte-macrophage colony-stimulating factor (GM-CSF) on human papillomavirus (HPV)-associated genital (pre)neoplastic lesions. The formulations were evaluated for their bioactivity and for their potential to recruit DC in organotypic cultures of HPV-transformed keratinocytes. We found that a bioadhesive polycarbophil gel (Noveon) at pH 5.5 is able to maintain the bioactivity of GM-CSF at 4 or 37°C for at least 7 days, whereas a decreased activity of GM-CSF was observed when the molecule is included in other polymer gels. GM-CSF incorporated in the polycarbophil gel was also a potent factor in enhancing the colonization of DC into organotypic cultures of HPV-transformed keratinocytes since the infiltration of DC in the in vitro-formed (pre)neoplastic epithelium was very low under basal conditions and dramatically increased in the presence of GM-CSF gel. We next demonstrated that GM-CSF incorporated in polycarbophil gel induces the recruitment of human DC in a human (pre)neoplastic epithelium grafted into NOD/SCID mice. The efficacy of GM-CSF in this formulation was equivalent to that observed with liquid GM-CSF. These results suggest that GM-CSF incorporated in polycarbophil gel could play an important role in the recruitment of DC/LC in mucosal surfaces and be useful as a new immunotherapeutic approach for genital HPV-associated (pre)neoplastic lesions. [less ▲]

Detailed reference viewed: 32 (4 ULg)
See detailDelivery of single polymer chains on a target substrate by AFM mechanochemistry
Cuenot, Stéphane; Jérôme, Christine ULg; Gabriel, Sabine ULg et al

Poster (2004, May 27)

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See detailDélivrable 15 - Rapport d'avancement Convention A
Dollé, Fabien ULg; Jamin, Pierre ULg; Gesels, Julie ULg et al

Report (2009)

Detailed reference viewed: 3 (3 ULg)
See detailDélivrable 16 - Rapport intermédiaire global présentant les travaux réalisés et les résultats acquis à la date du 5 février 2010
Pereira, Benoît; Schneider, Arnaud; Titeux, Hugues et al

Report (2010)

Detailed reference viewed: 31 (8 ULg)