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See detailDaytime 50 Hz Magnetic Field Exposure and Plasma Melatonin and Urinary 6-Sulfatoxymelatonin Concentration Profiles in Humans
Crasson, Marion ULg; Beckers, Véronique; Pequeux, Christel ULg et al

in Journal of Pineal Research (2001), 31(3), 234-41

Concern about the health effects of extremely low frequency (ELF) magnetic fields (MF) has been raised by epidemiological studies indicating an association between certain cancers and living near power ... [more ▼]

Concern about the health effects of extremely low frequency (ELF) magnetic fields (MF) has been raised by epidemiological studies indicating an association between certain cancers and living near power lines or working in high electric field environments. Alterations in pineal function have been proposed as a mechanism through which power-frequency MFs may interact with living organisms. A double blind laboratory study was performed to evaluate daytime exposure effects of 100 microT root mean square (rms) 50 Hz MF. Three head exposure sessions of 30 min each were performed: sham, continuous, and intermittent (15 s on/off cycles) MFs were presented to each subject in early or late afternoon (13:30 or 16:30 hr). Twenty-one healthy male volunteers (20-27 yr old) participated in these 3-weekly experimental conditions. Blood samples were drawn for serum melatonin measurement, hourly at night (from 20:00 to 07:00 hr) under controlled environmental conditions. Urinary excretion of 6-sulfatoxymelatonin (aMT6s), the main melatonin metabolite, was measured for a 17 hr period, by means of urine samples taken at 19:00 hr (14:00-19:00 hr "afternoon period"), 23:00 hr (19:00-23:00 hr "evening period"), and 07:00 hr, day 2 (23:00-07:00 hr day 2 "night-time period"). There were no significant differences in either plasma melatonin or in aMT6s excretion profiles in the three experimental conditions. However, a tendency for a smaller increase of night-time urinary aMT6s after continuous MF exposure was found (P=0.08) particularly in men with the lower excretion rate of aMT6s ("Low Group") (P=0.07). We conclude that this study does not indicate that daytime acute MF exposure influences either melatonin secretion or aMT6s excretion. Inter-individual differences in pineal production of melatonin, however, have to be taken into account in further studies. [less ▲]

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See detailDaytime light exposure dynamically enhances brain responses.
Vandewalle, Gilles ULg; Balteau, Evelyne ULg; Phillips, Christophe ULg et al

in Current Biology (2006), 16(16), 1616-21

In humans, light enhances both alertness and performance during nighttime and daytime [1-4] and influences regional brain function [5]. These effects do not correspond to classical visual responses but ... [more ▼]

In humans, light enhances both alertness and performance during nighttime and daytime [1-4] and influences regional brain function [5]. These effects do not correspond to classical visual responses but involve a non-image forming (NIF) system, which elicits greater endocrine, physiological, neurophysiological, and behavioral responses to shorter light wavelengths than to wavelengths geared toward the visual system [6-11]. During daytime, the neural changes induced by light exposure, and their time courses, are largely unknown. With functional magnetic resonance imaging (fMRI), we characterized the neural correlates of the alerting effect of daytime light by assessing the responses to an auditory oddball task [12-15], before and after a short exposure to a bright white light. Light-induced improvement in subjective alertness was linearly related to responses in the posterior thalamus. In addition, light enhanced responses in a set of cortical areas supporting attentional oddball effects, and it prevented decreases of activity otherwise observed during continuous darkness. Responses to light were remarkably dynamic. They declined within minutes after the end of the light stimulus, following various region-specific time courses. These findings suggest that light can modulate activity of subcortical structures involved in alertness, thereby dynamically promoting cortical activity in networks involved in ongoing nonvisual cognitive processes. [less ▲]

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See detail"Daz man bild mit bilden us tribe". Visual and Textual Image Theory in Henry Suso’s Exemplar
Falque, Ingrid ULg

Scientific conference (2012, May 30)

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See detailDBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Close, Pierre ULg; East, Phil; Svejstrup, Barbara et al

in Nature (2012)

Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to ... [more ▼]

Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription, and is greatly affected by the rate of transcript elongation1–3. As the nascent pre-mRNA emerges from transcribing RNA polymerase II (RNAPII), it is assembled into a messenger ribonucleoprotein (mRNP) particle; this is the functional form of the nascent pre-mRNA and determines the fate of the mature transcript4. However, factors that connect the transcribing polymerase with the mRNP particle and help to integrate transcript elongation with mRNA splicing remain unclear. Here we characterize the human interactome of chromatin-associated mRNP particles. This led us to identify deleted in breast cancer 1 (DBC1) and ZNF326 (which we call ZNF-protein interacting with nuclear mRNPs and DBC1 (ZIRD)) as subunits of a novel protein complex—named DBIRD—that binds directly to RNAPII. DBIRD regulates alternative splicing of a large set of exons embedded in (A 1 T)-rich DNA, and is present at the affected exons. RNAinterference- mediated DBIRD depletion results in region-specific decreases in transcript elongation, particularly across areas encompassing affected exons. Together, these data indicate that the DBIRD complex acts at the interface between mRNP particles and RNAPII, integrating transcript elongation with the regulation of alternative splicing. [less ▲]

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See detailDC and AC Shielding Properties of Bulk High-Tc Superconducting Tubes
Fagnard, Jean-François ULg; Denis, Samuel; Lousberg, Grégory ULg et al

in IEEE Transactions on Applied Superconductivity (2009), 19(3), 2905-2908

We have studied numerically and experimentally the magnetic flux penetration in high-Tc superconducting tube subjected to a uniform magnetic field parallel to its long axis. This study is carried in view ... [more ▼]

We have studied numerically and experimentally the magnetic flux penetration in high-Tc superconducting tube subjected to a uniform magnetic field parallel to its long axis. This study is carried in view of designing low-frequency magnetic shields by exploiting the diamagnetic properties of high-Tc superconducting ceramics. We have measured the field attenuation for applied magnetic fields in the frequency range 5 mHz-0.1 Hz by Hall probe measurements and at audio frequencies using a sensing coil. A simple 1D analysis using the Kim critical state model was found to be able to reproduce the experimental data satisfactorily. We have also determined the phase shift between the internal and the applied field both experimentally and numerically. Finally, we have studied the sweep rate dependence of the magnetic shielding properties, using data recorded either at several constant sweep rates dB/dt or at several AC fields of various amplitudes and frequencies. Both methods agree with each other and lead to a n -value of the E ~ J n law equal to ~ 40 at 77 K. [less ▲]

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See detailDC magnetron sputtering deposition of titanium oxide nanoparticles : influence
Dreesen, Laurent ULg; Cecchet, Francesca; Lucas, Stéphane

Conference (2008, September)

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See detailDC Magnetron Sputtering Deposition of Titanium Oxide Nanoparticles: Influence of Temperature, Pressure and Deposition Time on the Deposited Layer Morphology, the Wetting and Optical Surface Properties
Dreesen, Laurent ULg; Cecchet, Francesca; Lucas, Stéphane

in Plasma Processes and Polymers (2009), 6

Titanium dioxide nanoparticles were prepared on glass substrates by reactive DC magnetron sputtering. As highlighted by the atomic force microscopy characterization, we were able to control the ... [more ▼]

Titanium dioxide nanoparticles were prepared on glass substrates by reactive DC magnetron sputtering. As highlighted by the atomic force microscopy characterization, we were able to control the nanoparticles' surface coverage and diameter by varying the deposition time and the total pressure, respectively. The titanium dioxide energy band gap, determined by using ultraviolet-visible, spectroscopy, depends on the total pressure but is quite independent of the deposition temperature. On the contrary, it is blue shifted when the pressure increases. Finally, the contact angles slightly decrease after ultraviolet illumination irrespective of the different deposition parameters, indicating an improvement of the hydrophilic properties of the adsorbed layer. After 21 h in dark, the contact angles are nearly identical to the ones before exposure to UV light: the samples do not keep their hydrophilic behaviour. [less ▲]

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See detailDCD in liver transplantation
Detry, Olivier ULg

Conference (2010, January 29)

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See detailDCD kidney transplantation from 2000 to 2009: a Belgian review
Darius, T.; Ledinh, H.; Monbaliu, D. et al

Conference (2011, March 24)

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See detailDCD liver transplantation: is donor age an issue?
DETRY, Olivier ULg; Le dinh, Hieu; DE ROOVER, Arnaud ULg et al

in Liver Transplantation (2011, July), 17(6S1), 112

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See detailDCD liver transplantation: is donor age an issue?
DETRY, Olivier ULg; le dinh, Hieu; Honoré, Pierre ULg et al

Conference (2011, March 24)

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See detailDCDS - Distant Collaborative Design Studio. An Initial Experimentation in Distant Collaborative Design Studio in Architecture.
Elsen, Catherine ULg; Juchmes, Roland ULg; Kubicki, Sylvain et al

in Muylle, Marc (Ed.) Architecture "in computero", Integrating Methods and Techniques. Proceedings of the 26th eCAADe Conference on Education and Research in Computer Aided Architectural Design in Europe. (2008)

This paper introduces new supporting tools in the field of distant collaborative design, namely DCDS and CRTI-weB. These prototypes respectively support: the early stages of design, through the support of ... [more ▼]

This paper introduces new supporting tools in the field of distant collaborative design, namely DCDS and CRTI-weB. These prototypes respectively support: the early stages of design, through the support of the crucial initial step of free-hand sketches shared in real-time, and the asynchronous collaborative activities. The main goal of this paper is to propose the use of these innovative tools as an efficient and realistic way of managing long distance collaboration, to effectively serve the designers’ needs. This proposition is analyzed and questioned through a real-size experiment featuring 30 architecture and architectural-engineering students, working together in real-time in different locations (Belgium and France). This experiment and the necessary survey open up interesting fields of investigation, such as the relevance of the proposed devices in supporting distant collaborative design in architecture and the benefit this represents for students to merge the IT aspects and the design studio. The methodology and the replicability are analyzed to increase the level and quality of formation of our students and, finally, a critique of the tools confirms a benefit for the developing teams. [less ▲]

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See detailDD-carboxypeptidase-transpeptidase and killing site of β-lactam antibiotics in Streptomyces strains R39, R61, and K11
Dusart, Jean; Marquet, Alberto; Ghuysen, Jean-Marie ULg et al

in Antimicrobial Agents and Chemotherapy (1973), 3(2), 181-187

Additional evidence is given that in Streptomyces strains R39, R61, and K11 the same enzyme performs dd-carboxypeptidase and transpeptidase activities and that this enzyme is the killing site of beta ... [more ▼]

Additional evidence is given that in Streptomyces strains R39, R61, and K11 the same enzyme performs dd-carboxypeptidase and transpeptidase activities and that this enzyme is the killing site of beta-lactam antibiotics. With strain R61, it was found that the exocellular enzyme has a sensitivity towards some antibiotics different from that of the membrane-bound enzyme. Under the growth conditions used in the present investigations, beta-lactamase activity was not involved in susceptibility to beta-lactam antibiotics. [less ▲]

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See detailThe DD-carboxypeptidase-transpeptidase system in Escherichia coli mutant strain
Pollock, J. J.; Nguyen-Distèche, Martine ULg; Ghuysen, Jean-Marie ULg et al

in Annals of the New York Academy of Sciences (1974), 235

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See detailDD-carboxypeptidases and Mechanism of Action of Penicillin
Ghuysen, Jean-Marie ULg; Leyh-Bouille, Mélina; Nakel, M. et al

in Muñoz, E.; García-Ferrandiz, F.; Vazquez, D. (Eds.) Molecular mechanisms of antibiotic action on protein biosynthesis and membranes. Proceedings of a symposium held at the University of Granada (Spain) June 1st-4th (1971)

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See detailDD-carboxypeptidases/Transpeptidases and Penicillin Action
Perkins, Harold R; Ghuysen, Jean-Marie ULg; Nieto, Manuel et al

in 1st International Congress for Bacteriology, Jerusalem, 2-7 September, 1973. Abstracts. Vol I. Symposia (1973)

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See detailDe l'hagiographie. De ses sources, de ses méthodes et de son histoire. A propos de publications récentes
George, Philippe ULg

in Revue Belge de Philologie et d'Histoire (1998), LXXVI

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See detailDe "l'incapacité littéraire des Belges". Complexe national et contrefaçon
Droixhe, Daniel ULg; Ledain, O.

in Bertrand, Jean-Pierre; Biron, M.; Denis, Benoît (Eds.) et al Histoire de la littérature belge (1830-2000) (2003)

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See detailDe "La question" à la "sensure". L'imprimé en France face à la guerre d'Algérie
Sindaco, Sarah ULg

in Matière & l'Esprit (La) (2013)

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See detailDe "La Salle de bain" à "Fuir"
Demoulin, Laurent ULg

in Indications. La Revue des romans (2005), 62e série(5), 13-24

Description du parcours romanesque de Jean-Philippe Toussaint, centré sur son originalité et sur ses diverses évolutions stylistiques et narratologiques.

Detailed reference viewed: 65 (3 ULg)