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See detailCTIP2 is a negative regulator of P-TEFb.
Cherrier, Thomas ULg; Le Douce, Valentin; Eilebrecht, Sebastian et al

in Proceedings of the National Academy of Sciences of the United States of America (2013), 110(31), 12655-60

The positive transcription elongation factor b (P-TEFb) is involved in physiological and pathological events including inflammation, cancer, AIDS, and cardiac hypertrophy. The balance between its active ... [more ▼]

The positive transcription elongation factor b (P-TEFb) is involved in physiological and pathological events including inflammation, cancer, AIDS, and cardiac hypertrophy. The balance between its active and inactive form is tightly controlled to ensure cellular integrity. We report that the transcriptional repressor CTIP2 is a major modulator of P-TEFb activity. CTIP2 copurifies and interacts with an inactive P-TEFb complex containing the 7SK snRNA and HEXIM1. CTIP2 associates directly with HEXIM1 and, via the loop 2 of the 7SK snRNA, with P-TEFb. In this nucleoprotein complex, CTIP2 significantly represses the Cdk9 kinase activity of P-TEFb. Accordingly, we show that CTIP2 inhibits large sets of P-TEFb- and 7SK snRNA-sensitive genes. In hearts of hypertrophic cardiomyopathic mice, CTIP2 controls P-TEFb-sensitive pathways involved in the establishment of this pathology. Overexpression of the beta-myosin heavy chain protein contributes to the pathological cardiac wall thickening. The inactive P-TEFb complex associates with CTIP2 at the MYH7 gene promoter to repress its activity. Taken together, our results strongly suggest that CTIP2 controls P-TEFb function in physiological and pathological conditions. [less ▲]

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See detailCu doping as a tool for understanding CMR
Vertruyen, Bénédicte ULg; Cloots, Rudi ULg; Rulmont, André ULg et al

in Key Engineering Materials [=KEM] (2002), 206-2

Doping at the Mn-site in CMR manganate-based perovskites has been shown to affect strongly the physical properties of those compounds. We study here the effect of copper substitution in the low doping ... [more ▼]

Doping at the Mn-site in CMR manganate-based perovskites has been shown to affect strongly the physical properties of those compounds. We study here the effect of copper substitution in the low doping range on the electrical transport properties of La0.7Ca0.3MnO3. It turns out that the transition temperature decrease observed in doped samples can be drastically reduced by addition of silicon dioxide SiO2. It is shown that copper is trapped in a secondary phase composed of La,Ca,Si,Cu and O. The resultant Mn-site vacancies appear to be less detrimental to the electronic conduction than the likely antiferromagnetic clusters induced by the copper ions in the Mn-O network. [less ▲]

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See detailCu/carbon xerogel catalysts for the selective catalytic reduction of NO by NH3 : effect of the pore texture
Cabiac, A.; Job, Nathalie ULg; Pirard, Jean-Paul ULg et al

in Journal of Chemistry for Sustainable Development (2006), 6

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See detailCuba in tijden van periodo especial
Vanden Berghe, Kristine ULg

in Romaneske (1996), 21(1), 40-44

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See detailCubage des arbres et des peuplements forestiers - Tables et équations
Dagnelie, Pierre; Rondeux, Jacques ULg; Palm, Rodolphe ULg

Book published by Presses agronomiques de Gembloux (2013)

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See detailCubage et estimation des bois
Poskin, Arthur ULg

Book published by (Anc.) Institut agricole de l'Etat à Gembloux (1913)

L'estimation sert de base au trafic des produits forestiers. Pour estimer ceux-ci, autrement dit pour en apprécier la valeur, il est nécessaire d'en connaître le volume, c'est-à-dire de les cuber...

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See detailCubeSat Activities at the University of Liège
Denis, Amandine ULg; Pisane, Jonathan ULg; Verly, Jacques ULg et al

Conference (2011)

Detailed reference viewed: 23 (6 ULg)
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See detailCubic Pisot Unit Combinatorial Games
Duchêne, Eric; Rigo, Michel ULg

in Monatshefte für Mathematik (2008), 155

Generalized Tribonacci morphisms are de ned on a three letters alphabet and generate the so-called generalized Tribonacci words. We present a family of combinatorial removal games on three piles of tokens ... [more ▼]

Generalized Tribonacci morphisms are de ned on a three letters alphabet and generate the so-called generalized Tribonacci words. We present a family of combinatorial removal games on three piles of tokens whose set of P-positions is coded exactly by these generalized Tribonacci words. To obtain this result, we study combinatorial properties of these words like gaps between consecutive identical letters or recursive de nitions of these words. Beta-numeration systems are then used to show that these games are tractable, i.e., deciding whether a position is a P-position can be checked in polynomial time. [less ▲]

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See detailCubically convergent iterations for invariant subspace computation
Absil, P.-A.; Sepulchre, Rodolphe ULg; Van Dooren, P. et al

in SIAM Journal on Matrix Analysis and Applications (2004), 26(1), 70-96

We propose a Newton-like iteration that evolves on the set of fixed dimensional subspaces of R-n and converges locally cubically to the invariant subspaces of a symmetric matrix. This iteration is ... [more ▼]

We propose a Newton-like iteration that evolves on the set of fixed dimensional subspaces of R-n and converges locally cubically to the invariant subspaces of a symmetric matrix. This iteration is compared in terms of numerical cost and global behavior with three other methods that display the same property of cubic convergence. Moreover, we consider heuristics that greatly improve the global behavior of the iterations. [less ▲]

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See detailCucumis melo L. subsp. agrestis (Naudin) Pangalo (Cucurbitaceae) : nécessité d'une clarification sur le statut de la sous-espèce
Achigan-Dako, A. G.; Baudoin, Jean-Pierre ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(4), 283-286

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See detailCues from introduced fish alter shelter use and feeding behaviour in adult alpine newts
Winandy, Laurane ULg; Denoël, Mathieu ULg

in Ethology (2013), 119(2), 121-129

Amphibians are particularly affected by alien fish introductions and are declining worldwide. However, the behavioural mechanisms behind the observed cases of coexistence and exclusion patterns between ... [more ▼]

Amphibians are particularly affected by alien fish introductions and are declining worldwide. However, the behavioural mechanisms behind the observed cases of coexistence and exclusion patterns between adult amphibians and fish are poorly understood. In the present study, we aimed at testing the hypothesis that adult newts display different feeding and space use behaviour in the presence of fish cues (i.e. access less food resources and use more shelters than when fish cues are absent). To achieve this we measured behavioural patterns in 100 adult Alpine newts (Mesotriton alpestris) in a replicated laboratory design (20 tanks × 7 replicates across time). Half of trials involved individuals in indirect (visual and olfactory) contact with goldfish (Carassius auratus), a non-predatory species for adult newts. In the presence of fish, significantly more newts hid under shelters than in their absence, but this difference decreased over time. A lower number of newts fed in comparison with controls. These results show that newts responded to fish presence even in the absence of direct contact, but the differences were small. Newts decreased vital activities such as exploration of open areas and feeding. They also adjusted shelter use over time, suggesting a process of habituation or a risk assessment in the absence of direct risk. These results reveal that exploring behavioural patterns can aid in understanding the causes of exclusion and coexistence patterns between fish and amphibians. [less ▲]

Detailed reference viewed: 189 (60 ULg)
See detailLa cuisine du Cosmos. Traité de (G)astronomie
Nazé, Yaël ULg

Book published by Réjouisciences (2012)

Detailed reference viewed: 35 (1 ULg)
See detailCuivre et biodiversité au Katanga : stratégies de conservation et de valorisation d’un patrimoine exceptionnel.
Meerts, P; Shimba, N; Shutcha, M N et al

in Colloque « La quête des ressources naturelles en Afrique centrale. Le cas du secteur minier en RDC. (2008)

Detailed reference viewed: 27 (6 ULg)