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See detailThe core 2 beta-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins.
Markine-Goriaynoff, Nicolas; Gillet, Laurent ULg; Karlsen, Odd A et al

in Journal of General Virology (The) (2004), 85(Pt 2), 355-67

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only virus gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucine type (C2GnT-M). Recently ... [more ▼]

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only virus gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucine type (C2GnT-M). Recently, our phylogenetic study revealed that the Bo17 gene has been acquired from an ancestor of the African buffalo around 1.5 million years ago. Despite this recent origin, the Bo17 sequence has spread to fixation in the virus population possibly by natural selection. Supporting the latter hypothesis, it has been shown by our group for the V. test strain that Bo17 is expressed during BoHV-4 replication in vitro, and that Bo17 expression product (pBo17) has all three enzymic activities exhibited by cellular C2GnT-M, i.e. core 2, core 4 and I branching activities. In the present study, firstly it was investigated whether encoding a functional C2GnT-M is a general property of BoHV-4 strains. Analysis of nine representative strains of the BoHV-4 species revealed that all of them express the Bo17 gene and the associated core 2 branching activity during virus replication in vitro. Secondly, in order to investigate the roles of Bo17, its kinetic class of expression was analysed and a deleted recombinant strain was produced. These experiments revealed that Bo17 is expressed as an early gene which is not essential for virus replication in vitro. However, comparison of the structural proteins, produced by the wild-type, the revertant and the deleted viruses, by 2D gels demonstrated that pBo17 contributes to the post-translational modifications of structural proteins. Possible roles of Bo17 in vivo are discussed. [less ▲]

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See detailThe core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo
Markine-Goriaynoff, N.; Georgin, J. P.; Goltz, M. et al

in Journal of Virology (2003), 77(3), 1784-1792

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To ... [more ▼]

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the Bo17 gene, we analyzed its distribution among BoHV-4 strains and determined the sequences of Bo17 from nine representative strains and of the C2GnT-M gene from six species of ruminants expected to encompass the group within which the gene acquisition occurred. Of 34 strains of BoHV-4, isolated from four different continents, all were found to contain the Bo17 gene. Phylogenetic analyses indicated that Bo17 was acquired from a recent ancestor of the African buffalo, implying that cattle subsequently acquired BoHV-4 by cross-species transmission. The rate of synonymous nucleotide substitution in Bo17 was estimated at 5 x 10(-8) to 6 x 10(-8) substitutions/site/year, consistent with previous estimates made under the assumption that herpesviruses have cospeciated with their hosts. The Bo17 gene acquisition was dated to around 1.5 million years ago. Bo17 sequences from BoHV-4 strains from African buffalo and from cattle formed two separate clades, estimated to have split about 700,000 years ago. Analysis of the ratio of nonsynonymous to synonymous nucleotide substitutions revealed a burst of amino acid replacements subsequent to the transfer of the cellular gene to the viral genome, followed by a return to a strong constraint on nonsynonymous changes during the divergence of contemporary BoHV-4 strains. The Bo17 gene represents the most recent of the known herpesvirus gene acquisitions and provides the best opportunity for learning more about this important process of viral evolution. [less ▲]

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See detailCore Level Excitation in molecular Clusters.
Rühl, E.; Schmale, C.; Baumgärtel, H. et al

Book published by Berliner Elektronen Speicherring für Synchrotron Strahlung m.b.H (1991)

The photoionization of CO at the C-Kedge and that of its dimer are measured. The photodissociation of the cluster ion is investigated by PEPICO and PIPICO techniques.

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See detailCore Level Excitation of Atomic and Molecular Clusters.
Rühl, E.; Schmale, C.; Jochims, H. W. et al

in Beswick, A. (Ed.) Synchrotron Radiation and Dynamic Phenomena. (1992)

Core level excitation of weakly bonded atomic and molecular species is reported. Excitations into unoccupied orbitals with valence and Rydberg character as well as into the corresponding K- and L-continua ... [more ▼]

Core level excitation of weakly bonded atomic and molecular species is reported. Excitations into unoccupied orbitals with valence and Rydberg character as well as into the corresponding K- and L-continua are compared with the isolated and condensed species. Core level excitation of clusters is also accompagned with extensive fragmentation of singly and doubly charged clusters. Coincidence techniques such as photoelectron-photoion-coincidences (PEPICO) and photoion-photoion-coincidence (PIPICO) are used to study the photochemical fragmentation pathways of core excited clusters. Kinetic energy releases related to charge separation of cluster dications (Coulomb explosion) are derived from PIPICO spectra. The fragmentation energetics is discussed in relation to cluster dication threshold energies. [less ▲]

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See detailCore properties of α Centauri A using asteroseismology
de Meulenaer, P.; Carrier, F.; Miglio, A. et al

in Astronomy and Astrophysics (2010), 523

Context. A set of long and nearly continuous observations of α Centauri A should allow us to derive an accurate set of asteroseismic constraints to compare to models, and make inferences on the internal ... [more ▼]

Context. A set of long and nearly continuous observations of α Centauri A should allow us to derive an accurate set of asteroseismic constraints to compare to models, and make inferences on the internal structure of our closest stellar neighbour. <BR /> Aims: We intend to improve the knowledge of the interior of α Centauri A by determining the nature of its core. <BR /> Methods: We combined the radial velocity time series obtained in May 2001 with three spectrographs in Chile and Australia: CORALIE, UVES, and UCLES. The resulting combined time series has a length of 12.45 days and contains over 10 000 data points and allows to greatly reduce the daily alias peaks in the power spectral window. <BR /> Results: We detected 44 frequencies that are in good overall agreement with previous studies, and found that 14 of these show possible rotational splittings. New values for the large (Δν) and small separations (δν[SUB]02[/SUB], δν[SUB]13[/SUB]) have been derived. <BR /> Conclusions: A comparison with stellar models indicates that the asteroseismic constraints determined in this study (namely r[SUB]10[/SUB] and δν[SUB]13[/SUB]) allows us to set an upper limit to the amount of convective-core overshooting needed to model stars of mass and metallicity similar to those of α Cen A. [less ▲]

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See detailCore velocity dispersion and mass-to-light ratio of the old Magellanic globular cluster NGC 1835
Dubath, P.; Meylan, G.; Mayor, M. et al

in Astronomy and Astrophysics (1990), 239

Abstract image available at: http://adsabs.harvard.edu/abs/1990A&A...239..142D

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See detailCore Velocity Dispersion of the LMC Globular Cluster NGC 1835
Meylan, G.; Dubath, P.; Mayor, M. et al

in Bulletin of the American Astronomical Society (1989, January 01)

Not Available

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See detailCore-polarization effects and radiative lifetime measurements in Pr III
Biémont, Emile ULg; Garnir, Henri-Pierre ULg; Palmeri, P. et al

in Physical Review. A (2001), 64

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See detailCore-polarization effects in Cu II
Biémont, Emile ULg; Pinnington, E. H.; Quinet, Pascal ULg et al

in Physica Scripta (2000), 61

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See detailCore-polarization effects in doubly ionized cerium (Ce III) for transitions of astrophysical interest
Biémont, Emile ULg; Quinet, Pascal ULg; Ryabchikova, T. A.

in Monthly Notices of the Royal Astronomical Society (2002), 336(4), 1155-1160

The importance of core-polarization effects on oscillator strength determination in Ce III is emphasized. The inclusion of these effects in relativistic Hartree-Fock (HFR) calculations leads to ... [more ▼]

The importance of core-polarization effects on oscillator strength determination in Ce III is emphasized. The inclusion of these effects in relativistic Hartree-Fock (HFR) calculations leads to theoretical lifetime values for some 4f6p levels of this ion in close agreement with recent time-resolved laser-induced fluorescence measurements. These new atomic data, the most accurate to date, have allowed the refinement of the stellar abundance determination of cerium in the chemically peculiar star HD 192913, but have not altered in a drastic way the conclusions derived in recent analyses regarding the overabundance of this element. [less ▲]

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See detailCore-polarization effects in the Cadmium Isoelectronic Sequence
Biémont, Emile ULg; Froese Fischer, C.; Godefroid, M. R. et al

in Physical Review. A (2000), 62

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See detailCore-shell AgSiO2-Protoporphyrin IX nanoparticle: Effect of the Ag core on reactive oxygen species generation
Lismont, Marjorie ULg; Pàez Martinez, Carlos ULg; Dreesen, Laurent ULg

in SPIE proceeding - Colloidal Nanoparticles for Biomedical Applications X (2015, February)

Photodynamic therapy (PDT) for cancer is based on the use of a light sensitive molecule to produce, under specific irradiation, toxic reactive oxygen species (ROS). A way to improve the therapy efficiency ... [more ▼]

Photodynamic therapy (PDT) for cancer is based on the use of a light sensitive molecule to produce, under specific irradiation, toxic reactive oxygen species (ROS). A way to improve the therapy efficiency is to increase the amount of produced ROS near cancer cells. This aim can be achieved by using a metal enhanced process arising when an optically active molecule is located near a metallic nanoparticle (NP). Here, the coupling effect between silver (Ag) NPs and protoporphyrin IX (PpIX) molecules, a clinically approved photosensitizer, is studied compared first, to PpIX fluorescence yield and second, to ROS production efficiency. By applying a modified Stöber process, PpIX was encapsulated into a silica (SiO2) shell, surrounding a 60 nm sized Ag core. We showed that, compared to SiO2-PpIX NPs, Ag coated SiO2-PpIX NPs dramatically decreased PpIX fluorescence together with singlet oxygen production efficiency. However, after incubation time in the dark, the amount of superoxide anions generated by the Ag doped sample was higher than the control sample one. [less ▲]

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See detailCore-shell InP-CdS nanowires: fabrication and study
Zanolli, Zeila ULg; Wacaser, Brent A; Pistol, Mats-Erik et al

in Journal of Physics : Condensed Matter (2007), 19(29),

InP nanowires are fabricated by organo-metallic vapour phase epitaxy and studied via photoluminescence measurements performed on single nanowires, finding evidence of state filling with increasing ... [more ▼]

InP nanowires are fabricated by organo-metallic vapour phase epitaxy and studied via photoluminescence measurements performed on single nanowires, finding evidence of state filling with increasing excitation power density. To increase flexibility in fabrication technology we developed a wet chemical procedure to grow a CdS shell on these wires. In these InP–CdS wires the luminescence efficiency was decreased with respect to the bare wires. The CdS capping procedure needs further investigations to improve the emission properties of nanowires, in order to become technically useful. We suggest as possible improvements of this technique to increase the bath temperature and/or illuminate the sample with UV radiation during the capping procedure. [less ▲]

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See detailCore-Shell-Corona Micelles by PS-b-P2VP-b-PEO Copolymers: Focus on the Water-Induced Micellization Process
Willet, Nicolas ULg; Gohy, Jean-François; Auvray, Loïc et al

in Langmuir (2008), 24(7), 3009-3015

It is now well established that amphiphilic PS-b-P2VP-b-PEO linear triblock copolymers can form multilayered assemblies, thus core-shell-corona (CSC) micelles, in water. Micellization is triggered by ... [more ▼]

It is now well established that amphiphilic PS-b-P2VP-b-PEO linear triblock copolymers can form multilayered assemblies, thus core-shell-corona (CSC) micelles, in water. Micellization is triggered by addition of a small amount of water into a dilute solution of the PS-b-P2VP-b-PEO copolymer in a non-selective organic solvent. However, the phenomena that take place at the very beginning of this process are poorly documented. How these copolymer chains are perturbed by addition of water was investigated in this work by light and neutron scattering techniques and transmission electron microscopy. It was accordingly possible to determine the critical water concentration (CWC), the compactness of the nano-objects in solution, their number of aggregation, and their hydrodynamic diameter at each step of the micellization process. [less ▲]

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See detailCore-Shell-Corona micelles with a responsive shell
Willet, Nicolas ULg; Gohy, Jean-François; Jérôme, Robert ULg

Conference (2002, April 12)

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See detailCore-shell-corona micelles with a responsive shell
Gohy, Jean-François; Willet, Nicolas ULg; Varshney, Sunil et al

in Angewandte Chemie (International ed. in English) (2001), 40(17), 3214-3216

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See detailCore-shell-corona micelles: focus on the pH-responsive shell
Willet, Nicolas ULg; Gohy, Jean-François; Jérôme, Robert ULg

Conference (2005, October)

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See detailCoréférence et stratégie des fonctions parallèles dans le cas des pronoms anaphoriques ambigus
Rondal, Jean-Adolphe ULg; Leyen, N.; Brédart, Serge ULg et al

in Current Psychology of Cognition [=CPC] = Cahiers de Psychologie Cognitive [=CPC] (1984), 4

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See detailCorneille, bâtard de Bourgogne (ca 1426-1452)
Marchandisse, Alain ULg

in Bousmar, Éric; Marchandisse, Alain; Masson, Christophe (Eds.) et al La bâtardise et l'exercice du pouvoir en Europe du XIIIe au début du XVIe siècle (2015)

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