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See detailDefence Mechanisms and Coping Strategies among Caregivers in Palliative Care Units
Timmermann, Marie ULg; Naziri, Despina ULg; Etienne, Anne-Marie ULg

in Journal of Palliative Care (2009), 25(3), 181-190

This article focuses on the relationship between defence mechanisms, coping strategies, palliative attitude, and the well-being of caregivers in palliative care units, who are confronted with death ... [more ▼]

This article focuses on the relationship between defence mechanisms, coping strategies, palliative attitude, and the well-being of caregivers in palliative care units, who are confronted with death, suffering, and pain. They use many different defence mechanisms; however, studies linking their coping strategies and defence mechanisms are rare. This study uses a quantitative and qualitative design and is based on 18 caregivers (nurses) in 2 palliative care units in Belgium. Defence mechanisms are tested through a semi-structured interview, TAT, and DSQ-60. Coping strategies are evaluated through a semistructured interview, COPE, and WCQ. To maximize our global approach, coping strategies and defence mechanisms are associated with measures of wellbeing and palliative attitude. We determined that defence mechanisms and coping strategies should not be seen as obstacles to professional practices. Palliative caregivers are more likely to adopt “mature” and “mental inhibition and compromise formation” defence mechanisms, as well as “emotion-focused” and “problem-focused” coping strategies. Defence mechanisms are more unconscious and constitute appropriate answers in extreme emotional situations. Coping strategies allow for more conscious processes of adaptation to the environment of palliative care units. This study shows positive relationships between different defence mechanisms and coping strategies, palliative attitudes, and caregivers’ well-being. Institutions should improve the conditions for group exchange and for caregivers’ individual introspection so that caregivers develop adapted capacities to cope with anxiety. [less ▲]

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See detailDefence responses induced in tobacco cells by Bacillus lipopeptides acting as elicitors of systemic resistance in plants
Henry, G.; Jourdan, E.; Thonart, Philippe ULg et al

in Journal of Plant Pathology [=JPP] (2008), 90

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See detailDéfense anti-missile et dissuasion nucléaire : un jeu contradictoire, exclusif ou complémentaire ?
Dumoulin, André ULg

in revue de Défense nationale (2011), (2),

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See detailLa défense chimique chez les insectes
Laurent, Pascal ULg

Article for general public (2002)

Dans la nature, la survie d’une population animale est étroitement liée aux possibilités qu’elle a de se nourrir, de se reproduire et de se défendre vis-à-vis des prédateurs. Chez les insectes, cette ... [more ▼]

Dans la nature, la survie d’une population animale est étroitement liée aux possibilités qu’elle a de se nourrir, de se reproduire et de se défendre vis-à-vis des prédateurs. Chez les insectes, cette dernière nécessité est à l’origine de l’apparition, au cours de l’évolution, de mécanismes de défense plus ou moins sophistiqués chez de nombreuses espèces. Cet article discute des différents mécanismes de défense chez les insectes et présente plus particulièrement les défenses chimiques chez les chrysomèles, les coccinelles et les fourmis. [less ▲]

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See detailLa défense des libertés à l’épreuve des extrémismes politiques et religieux !
Jamin, Jérôme ULg

Article for general public (2008)

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See detailDéfense et illustration de l'analyse des discours universitaires
Defays, Jean-Marc ULg

in Defays, Jean-Marc; Englebert, Annick; Pollet, Marie-Christine (Eds.) et al Principes et typologie des discours universitaires (2009)

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See detailDefense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes
Paape, Max; Mehrzad, Jalil; Zhao, Xin et al

in Journal of Mammary Gland Biology and Neoplasia (2002), 7(2), 109-121

The primary phagocytic cells of the bovine mammary gland, polymorphonuclear neutrophil leukocytes (PMN), and macrophages, comprise the first line of defense against invading pathogens. In the normal ... [more ▼]

The primary phagocytic cells of the bovine mammary gland, polymorphonuclear neutrophil leukocytes (PMN), and macrophages, comprise the first line of defense against invading pathogens. In the normal healthy mammary gland, macrophages predominate and act as sentinels to invading mastitis-causing pathogens. Once invaders are detected, macrophages, and possibly mammary epithelial cells, release chemoattractants that direct migration of PMN into the area. In the mammary gland, protection is only effective if rapid influx of PMN from the circulation and subsequent phagocytosis and killing of bacteria occur. The second line of defense against infection consists of a network of memory cells and immunoglobulins that interact with the first line of defense. To minimize mammary tissue damage caused by bacterial toxins and oxidative products released by PMN, elimination of invading bacteria must proceed quickly. Therefore, the inflammatory response needs to be regulated. Hormones, metabolites, and acute phase proteins act to influence the outcome of mastitis, especially around parturition. The number of circulating PMN in cows during early lactation is highly heritable and closely related to susceptibility to clinical mastitis at this time. Advances in molecular biology are making available the tools, techniques, and products to study and modulate host-pathogen interactions. For example, the cloning and expression of proteins such as recombinant bovine soluble (rbos) CD (cluster of differentiation) 14 antigens, may provide ways of minimizing damaging effects of endotoxin during acute coliform mastitis. Soluble CD14 binds and neutralizes lipopolysacharide (LPS) and causes local recruitment of PMN after binding of CD14-LPS complexes to mammary epithelial cells. Development of transgenic animals that express rbosCD14 in their milk could prevent infection by Gram-negative pathogens. [less ▲]

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See detailDéfense végétale, biotechnologies et développement de bio-insecticides
Francis, Frédéric ULg; Blecker, Christophe ULg; Deroanne, Claude et al

in Abstract book (2006)

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See detailDefensis induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo
Hubert, Pascale ULg; Herman, Ludivine ULg; Maillard, Catherine ULg et al

in FASEB Journal (2007), 21(11), 2765-75

In addition to their direct antimicrobial activity, defensins might also influence adaptive immunity by attracting immature dendritic cells (DC). As these cells have been shown to be deficient in uterine ... [more ▼]

In addition to their direct antimicrobial activity, defensins might also influence adaptive immunity by attracting immature dendritic cells (DC). As these cells have been shown to be deficient in uterine cervix carcinogenesis, we evaluated the ability of -defensin (HNP-2, human neutrophil defensin 2) and ß-defensin (HßD2, human beta defensin 2) to stimulate their migration in human papillomavirus (HPV)-associated (pre)cancers. We first observed, using RT-PCR and immunohistology, that HßD2 is absent in HPV-transformed keratinocytes and that it is weakly expressed in cervical (pre)neoplastic lesions in comparison with normal keratinocytes. We next demonstrated that defensins exert a chemotactic activity for DC in a Boyden Chamber assay and stimulate their infiltration in an in vitro-formed (pre)neoplastic epithelium (organotypic culture of HPV-transformed keratinocytes). To evaluate the ability of defensins also to recruit DC in vivo, we developed a model of immunodeficient mice grafted with organotypic cultures of HPV+ keratinocytes, which form an epithelium similar to a high-grade neoplastic lesion, with tumoral invasion and neovascularization. Intravenously injected human DC were able to infiltrate grafts of HPV+ keratinocytes after administration of HNP-2 in the transplantation chamber. Taken together, these results suggest that defensins could reverse a frequent immune alteration observed in cancer development. [less ▲]

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See detailDeffand, Marie de Vichy-Chamrond, marquise du
Tilkin, Françoise ULg

in Voir barré (1996), 12-13

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See detailLe défi de la diversité linguistique des apprenants pour l’apprentissage de la lecture et de l’écriture
Lucchini, Silvia ULg; Flamini, F.; Campolini, L.

in Langues Modernes (2001), (1), 34-41

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See detailLE DÉFI DU CONTRÔLE LOCAL DANS LE CANCER PULMONAIRE NON A PETITES CELLULES, LOCALEMENT AVANCE, NON OPERABLE
BARTHELEMY, Nicole ULg; LENNERTS, Evelyne ULg; MEYNS, Mia ULg et al

in Revue Médicale de Liège (2014), 69(Supp 1), 75-80

Le cancer broncho-pulmonaire non à petites cellules (CBNPC) est fréquent. Pour près d’un patient sur cinq, au moment du diagnostic, la maladie est déjà localement avancée et inopérable. A ce stade, le ... [more ▼]

Le cancer broncho-pulmonaire non à petites cellules (CBNPC) est fréquent. Pour près d’un patient sur cinq, au moment du diagnostic, la maladie est déjà localement avancée et inopérable. A ce stade, le pronostic de cette affection est mauvais, caractérisé, entre autres, par un taux élevé de réci - dive locale, malgré la chimiothérapie et la radiothérapie. Le but de cette revue est de décrire l’hétérogénéité de ce groupe de patients, de clarifier les modalités de traitement combinant la chimiothérapie et la radiothérapie et de préciser l’intérêt des techniques modernes de radiothérapie pour améliorer le contrôle local [less ▲]

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