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Computerized assessment of cognition in schizophrenia: promises and pitfalls of CANTAB. Levaux, Marie-Noëlle ; ; et al in European Psychiatry (2007), 22(2), 104-15 OBJECTIVE: Over the last decade, the Cambridge Neuropsychological Test Automated Battery (CANTAB), which comprises visuo-spatial tasks, has been utilized in cognitive studies of schizophrenia. A clear ... [more ▼] OBJECTIVE: Over the last decade, the Cambridge Neuropsychological Test Automated Battery (CANTAB), which comprises visuo-spatial tasks, has been utilized in cognitive studies of schizophrenia. A clear approach concerning the usage of CANTAB for the appraisal of neurocognitive dysfunction in schizophrenia is currently lacking. METHOD: In this paper, we have first reviewed the overall applications of CANTAB and then evaluated methodological strengths and weaknesses of CANTAB as a neurocognitive battery for schizophrenia. We carried out a systematic search and assessment of studies where CANTAB was utilized to measure cognitive function in schizophrenia. We have also attempted to quantify the available data and perform a meta-analysis, but this approach turned out to be still premature. RESULTS: CANTAB has enabled researchers to highlight significant deficits affecting broad cognitive domains in schizophrenia, such as working memory, decision-making, attention, executive functions and visual memory. So far, the most consistent deficit observed with CANTAB testing has been attentional set-shifting, suggestive of fronto-striatal dysfunctions. In addition, preliminary evidence points towards the potential use of CANTAB to identify cognitive predictors of psychosocial functioning, to describe the relationships between symptoms and cognition, and to measure the impact of pharmacological agents on cognitive functioning. CONCLUSION: CANTAB has been used successfully to highlight the range of visuo-spatial cognitive deficits in schizophrenia, producing similar results to those obtained with some traditional neuropsychological tests. Further studies validating the use of CANTAB following the standard set by Measurement And Treatment Research to Improve Cognition in Schizophrenia (MATRICS) are warranted. [less ▲] Detailed reference viewed: 74 (2 ULg)The Computerized Meeting Preparation Task: measuring multitasking to predict real world functioning of persons diagnosed with schizophrenia. Laloyaux, Julien ; Van der Linden, Martial ; Levaux, Marie-Noëlle et al Poster (2013, June) Detailed reference viewed: 65 (7 ULg)A computerized method adapted for pulmonary function testing in unsedated horses Lekeux, Pierre in Deegen, E.; Beadle, R. E. (Eds.) Lung Function and Respiratory Diseases in the Horse (1985) Detailed reference viewed: 8 (1 ULg)A computerized open learning environment to study intrapersonal variations in learning styles : DELIN Leclercq, Dieudonné ; in Estes, N. (Ed.) Proceedings of the 6th International Conference on Technology and Education (ICTE), Orlando, Florida, March 21-23, 1989 (1989, March) Several studies have been devoted to interpersonal differences in so-called "cognitive styles" (Kagan & Kogan), 1970; WItking & Goodenough, 1977; Pask, 1976, etc.). Pask himself has emphasised the notion ... [more ▼] Several studies have been devoted to interpersonal differences in so-called "cognitive styles" (Kagan & Kogan), 1970; WItking & Goodenough, 1977; Pask, 1976, etc.). Pask himself has emphasised the notion of versatility, i.e. the individual's capacity to switch from a strategy to an other, according to changes in conditions, constrains, etc.In order to respect both the interpersonal and intrapersonal variations in learning strategies, we have developed a software of the hypermedia type called DELIN (from the French DELINEARISE, that means non linear. [less ▲] Detailed reference viewed: 71 (6 ULg)Computerized tailored testing: Structured and calibred item banks for summative and formative evaluation Leclercq, Dieudonné in European Journal of Education (1980), 15(3), 251-260 Detailed reference viewed: 13 (3 ULg)Computerized three dimensional visualization of silver stained nucleolar organizer regions studied by high voltage electron microscopy ; ; et al in Biology of the Cell (1990), 69 Detailed reference viewed: 4 (0 ULg)Computerized video multitracking of several small translucent fishes (glass eels) at night with fluorescent elastomer tags Delcourt, Johann ; ; Ylieff, Marc et al Poster (2010, July) European eels (Anguilla Anguilla), an endangered species with high economic value, exhibit very unusual features in their multistage catadromous life cycle at different life stages. The reproduction of ... [more ▼] European eels (Anguilla Anguilla), an endangered species with high economic value, exhibit very unusual features in their multistage catadromous life cycle at different life stages. The reproduction of eel takes place in the Sargasso Sea. Leptocephalus larvae use ocean currents (mainly the Gulf Stream) to migrate to European coastal areas, and then metamorphose into glass eels probably as they reach the continental shelf. Glass eel then, enter estuaries to join the fresh waters network. Knowledge about glass eel biology and migration has mainly increased in the eighties, and it is now well established that the activity during the estuary migration depends mainly on tidal cycle, even if lunar and circadian rhythms and/or direct influence of light and tidal coefficient may interact. Different migratory tactics are suspected on the basis of recent laboratory experiments (Bolliet & Labonne, 2008; Bureau du Colombier et al., 2009), notably the existence of individuals swimming only with the current, others swimming with and against the current, and others presenting a weak degree of activity. The propensity to migrate and glass eels energy content would be linked and may result in different migratory behaviours possibly leading to estuarine settlement (Bureau du Colombier et al., 2007; 2009). Unfortunately, few are known about the glass eel swimming behaviours in estuaries, a crucial point to better understand their estuarine migration: such knowledge would help to characterize the migratory tactics and to better understand the link with energy status. The videotracking system [EthoVision Color-Pro 3.1 (Noldus Information Technology)] which allows to measure automatically the movements of individuals represents an interesting tool to progress in this questioning. Nowadays, video tracking to measure fish behaviours is relatively frequent, but is rather rare in the ecological studies. Moreover, tracking a transparent animal, under water current conditions is a real challenge, particularly at night. To detect the individuals, several eels are marked by a fluorescent VIE tag (Visible Implant Elastomer, Northwest Marine Technology Inc.). VIE do no affect growth, survival and behaviour of tagged glass eels. Initially developed to improve the identification of individual tags in mark-recapture studies of aquatic animals, VIE tags are used here for a new extreme application in ethometry: the study of behaviours of transparent animals in weaker luminosity and in the dark by automatic tracking technology. The individual identification is based on the fluorescent color (red, blue, yellow and green) emitted by the VIE tag injected in the muscle mass on the basis of dorsal fin. The detection of the four marks is excellent. It allows measuring the activity (notably path and speed) of each tagged individuals as a function of tidal and nycthemeral rhythms in the same chronotron (circular aquarium simulating the estuarine conditions) and spatial use at a wide time scale from second to week. Another advantage is the possibility of tracked animals to go out the analysed arena without error of identification when it appears again in the analysed zone. This multitracking method by fluorescent VIE tags could be applied to a large number of species (crustaceans, fish, holothurians, amphibians, …). References: Bolliet & Labonne, 2008 Journal of Experimental Marine Biology and Ecology 362, 125-130; Bureau du Colombier et al., 2007 Physiology & Behavior 92, 684-690 ; Bureau du Colombier et al., 2009 Journal of Fish Biology 74, 2002-2013. Acknowledgements: This work was financially supported by FNRS-FRS (National fund of Research, Belgium) (project n°2.4617.08, n°2.4569.06, n°2.4569.10F), by Hubert Curien Tournesol project and by an EGIDE Grant. We thank J-C. Aymes for its help in testing the video tracking software and system. We are also highly grateful to Jacques Rives for its help in settling and monitoring the experiments. [less ▲] Detailed reference viewed: 135 (8 ULg)Computers As Genomic Time Machines for Meeting our Ancestors Baurain, Denis Scientific conference (2013, April 18) Detailed reference viewed: 31 (4 ULg)Computers in Veterinary Medicine - The situation in Belgium Leroy, Pascal in UEVP's Electronic Data Processing, München, 1983 (1983) Detailed reference viewed: 6 (0 ULg)Computing accurately the induced land subsidence affecting the main sinking cities located at major river mouths Dassargues, Alain in Advances in Hydro-Science and Engineering - Volume 1 -ICHE Washington (1993) Detailed reference viewed: 18 (5 ULg)COMPUTING ANTICIPATORY SYSTEMS, CASYS'09 - Ninth International Conference, Liège, Belgium, 3-8 August 2009 Dubois, Daniel Book published by American Institute of Physics (2010) Detailed reference viewed: 45 (2 ULg)Computing bounds for kernel-based policy evaluation in reinforcement learning Fonteneau, Raphaël ; ; Wehenkel, Louis et al Report (2010) This technical report proposes an approach for computing bounds on the finite-time return of a policy using kernel-based approximators from a sample of trajectories in a continuous state space and ... [more ▼] This technical report proposes an approach for computing bounds on the finite-time return of a policy using kernel-based approximators from a sample of trajectories in a continuous state space and deterministic framework. [less ▲] Detailed reference viewed: 18 (3 ULg)Computing bounds on the geometrical quality of 2D curvilinear finite elements Johnen, Amaury ; ; et al Conference (2013, April 25) The development of high-order computational methods for solving partial differen- tial equations on unstructured grids has been underway for many years. Such meth- ods critically depend on the ... [more ▼] The development of high-order computational methods for solving partial differen- tial equations on unstructured grids has been underway for many years. Such meth- ods critically depend on the availability of high-quality curvilinear meshes, as one badly-shaped element can degrade the solution in the whole domain (J. Shewchuk, “What Is a Good Linear Finite Element? Interpolation, Conditioning, Anisotropy, and Quality Measures”, Preprint, 2002). The usual way of generating curved meshes is to first generate a straight sided mesh and to curve mesh entities that are classified on the boundaries of the domain. The latter operation introduces a “shape-distortion” that should be controlled if we suppose that the straight sided mesh is composed of well-shaped elements. Quality measures allow to quantify to which point an element is well-shaped. They also provide tools to improve the quality of meshes through optimization opera- tions. Many quality measures has been proposed for quadratic triangular finite element. Recently, X. Roca et al. (“Defining Quality Measures for High-Order Planar Triangles and Curved Mesh Generation”, Proceedings of the 20th Interna- tional Meshing Roundtable, 2011) proposed a technique that allows extending any Jacobian based quality measure for linear elements to high-order iso-parametric planar triangles of any interpolation degree. In this work we propose an efficient method to provide accurate bounds on the mag- nitude of the shape distortion of any triangular and quadrangular curved element. The shape distortion is measured with respect to an ideal element, which can e.g. be an equilateral triangle or the element from the original straight-sided mesh. The key feature of the method is that we can adaptively expand functions based on the Jacobian matrix and its determinant in terms of Be ́zier functions. Be ́zier functions have both properties of boundedness and positivity, which allow sharp computation of minimum or maximum of the interpolated functions. [less ▲] Detailed reference viewed: 80 (20 ULg)Computing Convex Hulls by Automata Iteration Cantin, François ; ; Wolper, Pierre in International Journal of Foundations of Computer Science (2009), 20(4), 647-667 This paper considers the problem of computing the real convex hull of a finite set of n-dimensional integer vectors. The starting point is a finite-automaton representation of the initial set of vectors ... [more ▼] This paper considers the problem of computing the real convex hull of a finite set of n-dimensional integer vectors. The starting point is a finite-automaton representation of the initial set of vectors. The proposed method consists in computing a sequence of automata representing approximations of the convex hull and using extrapolation techniques to compute the limit of this sequence. The convex hull can then be directly computed from this limit in the form of an automaton-based representation of the corresponding set of real vectors. The technique is quite general and has been implemented. [less ▲] Detailed reference viewed: 78 (23 ULg)Computing Convex Hulls by Automata Iteration Cantin, François ; ; Wolper, Pierre in Lecture Notes in Computer Science (2008, July), 5148 This paper considers the problem of computing the real convex hull of a finite set of n-dimensional integer vectors. The starting point is a finite-automaton representation of the initial set of vectors ... [more ▼] This paper considers the problem of computing the real convex hull of a finite set of n-dimensional integer vectors. The starting point is a finite-automaton representation of the initial set of vectors. The proposed method consists in computing a sequence of automata representing approximations of the convex hull and using extrapolation techniques to compute the limit of this sequence. The convex hull can then be directly computed from this limit in the form of an automatonbased representation of the corresponding set of real vectors. The technique is quite general and has been implemented. Also, our result fits in a wider scheme whose objective is to improve the techniques for converting automata-based representation of constraints to formulas. [less ▲] Detailed reference viewed: 96 (37 ULg)Computing k-binomial equivalence and avoiding binomial repetitions Rigo, Michel Conference (2015, October 28) In this talk, I will first recall basic results on binomial coefficients of words, then review the connections and differences with Parikh matrices. As a generalization of abelian equivalence, two words u ... [more ▼] In this talk, I will first recall basic results on binomial coefficients of words, then review the connections and differences with Parikh matrices. As a generalization of abelian equivalence, two words u and v are k-binomially equivalent if every word of length at most k appears as a subword of u exactly as many times as it appears as a subword of v. So a k-binomial square is a word uv where u and v are k-binomially equivalent. We will discuss avoidance of squares and cubes in infinite words (this is a joint word with M. Rao). Finally, I will consider the question of deciding whether or not two finite words are k-binomially equivalent. This problem has recently been shown to be decidable in polynomial time by Freydenberger, Gawrychowski et al. [less ▲] Detailed reference viewed: 47 (8 ULg)Computing near-optimal policies from trajectories by solving a sequence of standard supervised learning problems Ernst, Damien Speech/Talk (2006) Detailed reference viewed: 12 (3 ULg)Computing system signatures through reliability functions ; Mathonet, Pierre in Statistics & Probability Letters (2013), 83(3), 710-717 It is known that the Barlow-Proschan index of a system with i.i.d. component lifetimes coincides with the Shapley value, a concept introduced earlier in cooperative game theory. Due to a result by Owen ... [more ▼] It is known that the Barlow-Proschan index of a system with i.i.d. component lifetimes coincides with the Shapley value, a concept introduced earlier in cooperative game theory. Due to a result by Owen, this index can be computed efficiently by integrating the first derivatives of the reliability function of the system along the main diagonal of the unit hypercube. The Samaniego signature of such a system is another important index that can be computed for instance by Boland's formula, which requires the knowledge of every value of the associated structure function. We show how the signature can be computed more efficiently from the diagonal section of the reliability function via derivatives. We then apply our method to the computation of signatures for systems partitioned into disjoint modules with known signatures. [less ▲] Detailed reference viewed: 29 (2 ULg)Computing the derivatives of the mean and amplitude of physiological variables with respect to the parameters of a mathematical model Pironet, Antoine ; Dauby, Pierre ; et al Conference (2013, September 06) Detailed reference viewed: 32 (6 ULg)Computing the Field of nth Order Accelerations in Rigid Motion by Direct Measurements ; Martinusi, Vladimir in Bulletin of the Polytechnic Institute of Jasi. Section Mathematics, Theoretical Mechanics, Physics = Buletinul Institutului Politehnic din Iaşi. Secţia Matematica, Mecanica Teoretica, Fizica (2006), LII (LVI)(6), Detailed reference viewed: 14 (1 ULg) |
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