Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailDécouverte laparoscopique d'une leiomyomatose péritonéale disséminée: une étroite ressemblance avec la carcinose péritonéale métastatique
Heidebroek, A.; Gielen, J. L.; Kolh, Philippe ULg et al

in Annales de Chirurgie (1998), 52(3), 298-300

Detailed reference viewed: 38 (2 ULg)
Full Text
Peer Reviewed
See detailDécouverte récente de Nyctalus leisleri en Corse
Libois, Roland ULg

in Mammalia (1983), 47(3), 425-426

Detailed reference viewed: 4 (1 ULg)
Full Text
See detailLes découvertes épigraphiques des fouilles récentes de Mari. Etat des recherches en janvier 2009.
Colonna d'Istria, Laurent ULg; Cavigneaux, Antoine

in Studia Orontica دراسات العاص (2009), VI

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailDécouvertes récentes dans la chimie des alcaloïdes du Strychnos usambarensis GILG
Angenot, Luc ULg; Denoël, Albert

in Plantes médicinales et phytothérapie (1973), 7(4), 284-292

Six bis-indole alkaloids have been isolated from the rootbark of Strychnos usambarensis.Four alkaloids ( usambarensine and derivatives) are unsymmetrical bis-indole products, biogenetically derived from ... [more ▼]

Six bis-indole alkaloids have been isolated from the rootbark of Strychnos usambarensis.Four alkaloids ( usambarensine and derivatives) are unsymmetrical bis-indole products, biogenetically derived from two tryptaminic and one monoterpene units as some alkaloids of Apocynaceae (Ochrosia) and Rubiaceae ( Uncaria), two families very close to Loganiaceae from a chemotaxonomy point of view. Two other alkaloids (C-dihydrotoxiferine and C_Curarine) are symmetrical bis-indole quaternary products. These potent compounds were previously isolated from calabash-curare and some American Strychnos. Furthermore, we have isolated loganic acid and discussed the part that it could take in the biogenesis of various alkaloids. [less ▲]

Detailed reference viewed: 47 (1 ULg)
See detailDécouvrir la « lecture littéraire » avec des romans écrits pour la jeunesse
Delbrassine, Daniel ULg

Book published by Presses Universitaires de Namur (2007)

Le roman pour la jeunesse est un instrument utile au service de l'enseignement de la lecture littéraire: démonstration et illustration, à travers 5 séquences de cours fondées sur l'usage de romans ... [more ▼]

Le roman pour la jeunesse est un instrument utile au service de l'enseignement de la lecture littéraire: démonstration et illustration, à travers 5 séquences de cours fondées sur l'usage de romans contemporains adressés aux adolescents. [less ▲]

Detailed reference viewed: 52 (12 ULg)
See detailDécouvrir le ciel; Le guide de l'astronomie facile -- J. L. Halbwachs
Manfroid, Jean ULg

in Ciel et Terre (1987), 103

Not Available

Detailed reference viewed: 3 (0 ULg)
See detailDécouvrir, comprendre, préserver et diffuser la biodiversité des plantes cultivées.
Gillet, Joël; Gricourt, Olivier; Bindelle, Jérôme ULg

Article for general public (2005)

Detailed reference viewed: 7 (0 ULg)
Full Text
See detailDECPHOT: An Optimal Deconvolution-based Photometric Reduction Method
Gillon, Michaël ULg; Magain, Pierre ULg; Chantry, Virginie ULg et al

in Transiting Extrapolar Planets Workshop (2007, July 01)

A high accuracy photometric reduction method is needed to take full advantage of the potential of the transit method for the detection and characterization of exoplanets, especially in deep crowded fields ... [more ▼]

A high accuracy photometric reduction method is needed to take full advantage of the potential of the transit method for the detection and characterization of exoplanets, especially in deep crowded fields. In this context, we present DECPHOT, a new deconvolution-based photometry algorithm able to deal with a very high level of crowding and large variations of seeing. It also increases the resolution of astronomical images, an important advantage for the discrimination of false positives in transit photometry. [less ▲]

Detailed reference viewed: 67 (18 ULg)
Full Text
Peer Reviewed
See detailDecrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice.
Louis, Edouard ULg; Franchimont, D.; Deprez, Manuel ULg et al

in International Archives of Allergy & Immunology (1996), 109(1), 21-6

The oral administration of non-steroidal anti-inflammatory drugs (NSAID) to animals induces a quick increase in intestinal permeability and secondary inflammatory lesions of the intestine. The mechanisms ... [more ▼]

The oral administration of non-steroidal anti-inflammatory drugs (NSAID) to animals induces a quick increase in intestinal permeability and secondary inflammatory lesions of the intestine. The mechanisms leading to the inflammatory lesions are hypothetical. The increased intestinal permeability could allow a greater mucosal and systemic penetration of fed antigens and bacterial products leading to an abnormal mucosal and systemic immune and inflammatory response toward these materials. We examined the effect of oral dosing with indomethacin on ovalbumin serum levels and the systemic immune response to ovalbumin in mice fed with ovalbumin. The ovalbumin serum level was higher in indomethacin-treated mice and the increase was proportional to the dose of indomethacin. It was associated with epithelial and subepithelial lesions. Moreover, the systemic humoral and, to a lesser extent, the cellular tolerance were partially abrogated in the treated mice. These findings suggest that the oral administration of indomethacin in mice induces an increased passage of fed antigen through the intestinal epithelium associated with a decrease in systemic tolerance to this antigen. The reason for this decrease remains unclear. Besides a disequilibrium between systemic and mucosal immune responses, a loss of integrity of the intestinal epithelial cells and a direct immunomodulating effect of indomethacin may also be involved. This decrease in systemic tolerance to luminal antigen could be involved in the development of NSAID enteropathy. [less ▲]

Detailed reference viewed: 37 (13 ULg)
Full Text
Peer Reviewed
See detailDecrease Of Elastic Moduli Of Dopc Bilayers Induced By A Macrolide Antibiotic, Azithromycin
Fa, N.; Lins, Laurence ULg; Courtoy, Pj. et al

in Biochimica et Biophysica Acta-Biomembranes (2007), 1768(7), 1830-8

The elastic properties of membrane bilayers are key parameters that control its deformation and can be affected by pharmacological agents. Our previous atomic force microscopy studies revealed that the ... [more ▼]

The elastic properties of membrane bilayers are key parameters that control its deformation and can be affected by pharmacological agents. Our previous atomic force microscopy studies revealed that the macrolide antibiotic, azithromycin, leads to erosion of DPPC domains in a fluid DOPC matrix [A. Berquand, M. P. Mingeot-Leclercq, Y. F. Dufrene, Real-time imaging of drug-membrane interactions by atomic force microscopy, Biochim. Biophys. Acta 1664 (2004) 198-205.]. Since this observation could be due to an effect on DOPC cohesion, we investigated the effect of azithromycin on elastic properties of DOPC giant unilamellar vesicles (GUVs). Microcinematographic and morphometric analyses revealed that azithromycin addition enhanced lipid membranes fluctuations, leading to eventual disruption of the largest GUVs. These effects were related to change of elastic moduli of DOPC, quantified by the micropipette aspiration technique. Azithromycin decreased both the bending modulus (k(c), from 23.1+/-3.5 to 10.6+/-4.5 k(B)T) and the apparent area compressibility modulus (K(app), from 176+/-35 to 113+/-25 mN/m). These data suggested that insertion of azithromycin into the DOPC bilayer reduced the requirement level of both the energy for thermal fluctuations and the stress to stretch the bilayer. Computer modeling of azithromycin interaction with DOPC bilayer, based on minimal energy, independently predicted that azithromycin (i) inserts at the interface of phospholipid bilayers, (ii) decreases the energy of interaction between DOPC molecules, and (iii) increases the mean surface occupied by each phospholipid molecule. We conclude that azithromycin inserts into the DOPC lipid bilayer, so as to decrease its cohesion and to facilitate the merging of DPPC into the DOPC fluid matrix, as observed by atomic force microscopy. These investigations, based on three complementary approaches, provide the first biophysical evidence for the ability of an amphiphilic antibiotic to alter lipid elastic moduli. This may be an important determinant for drug: lipid interactions and cellular pharmacology. [less ▲]

Detailed reference viewed: 4 (1 ULg)
Peer Reviewed
See detailDecrease of frontal metabolism demonstrated by positron emission tomography in a population of healthy elderly volunteers.
Salmon, Eric ULg; Maquet, Pierre ULg; Sadzot, Bernard ULg et al

in Acta Neurologica Belgica (1991), 91(5), 288-95

Frontal metabolism measured with positron emission tomography is shown to be decreased relatively to that in other cortical or sub-cortical areas, in a population of healthy elderly compared to young ... [more ▼]

Frontal metabolism measured with positron emission tomography is shown to be decreased relatively to that in other cortical or sub-cortical areas, in a population of healthy elderly compared to young volunteers. Cortical atrophy or neuronal depopulation are unlikely to entirely explain this physiological phenomenon, and sub-cortico-cortical deactivation should play a role, analogous to that proposed in subcortical diseases. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailDecrease of Plasma Vitamin E (Alpha-Tocopherol) Levels in Patients with Abdominal Aortic Aneurysm
Sakalihasan, Natzi ULg; Pincemail, Joël ULg; Defraigne, Jean-Olivier ULg et al

in Annals of the New York Academy of Sciences (1996), 800

Detailed reference viewed: 40 (13 ULg)
Full Text
Peer Reviewed
See detailDecrease of serum concentrations of dioxins and PCBs in Belgium between 2000 and 2003
Fierens, Sébastien; Heilier, Jean-François; Eppe, Gauthier ULg et al

in Organohalogen Compounds (2005), 67

Detailed reference viewed: 7 (0 ULg)
Peer Reviewed
See detailDecrease of T-Lymphocyte Proliferation in Exercise-Induced Asthma
Bury, Thierry ULg; Corhay, Jean-Louis ULg; Louis, Renaud ULg et al

in Allergy (1994), 49(8), 605-10

The present study was designed to examine the effect of physical exercise on T-lymphocyte proliferation in patients with exercise-induced asthma (EIA). Indeed, a decrease in different immune functions is ... [more ▼]

The present study was designed to examine the effect of physical exercise on T-lymphocyte proliferation in patients with exercise-induced asthma (EIA). Indeed, a decrease in different immune functions is described in normal man after exercise. Thirty subjects (10 normal and 20 asthmatic subjects with or without EIA) underwent a submaximal exercise test on an electrically driven treadmill. Before and after this test, ventilatory variables were measured, and venous blood was taken to study plasma histamine (RIA) and spontaneous and phytohemagglutinin (PHA)-pulsed T-lymphocyte proliferation (mononuclear cells isolated on Ficoll-Hypaque; tritiated thymidine incorporation). Ten minutes after the end of the exercise, there was a significant FEV1 decrease only in asthmatic subjects with EIA (mean: 24 +/- 5%). In the same group, the mean plasma histamine level was 0.31 ng/ml-1 (+/- 0.06) before the challenge. It rose to 0.62 ng/ml-1 (+/- 0.14) 10 min after the end of the exercise (P < 0.05), and returned to normal limits 20 min after the test. In this group, there was also a significant decrease (by about 35%) of spontaneous and PHA-pulsed T-lymphocyte proliferation 2 and 4 h after the exercise. By contrast, exercise challenge had no effect on either plasma histamine level or T-lymphocyte proliferation in the normal group. Our results show a rapid and transient increase in plasma histamine in EIA. This was followed 2 and 4 h later by a significant decrease of T-lymphocyte proliferation. A possible relationship between these two phenomena is discussed. [less ▲]

Detailed reference viewed: 25 (2 ULg)
Full Text
Peer Reviewed
See detailDecrease of the Carbon Tetrachloride (CCl4) Loading above Jungfraujoch, based on High Resolution Infrared Solar Spectra recorded between 1999 and 2011
Rinsland, C. P.; Mahieu, Emmanuel ULg; Demoulin, Philippe ULg et al

in Journal of Quantitative Spectroscopy & Radiative Transfer (2012), 113

The long-term trend of the atmospheric carbon tetrachloride (CCl4) burden has been retrieved from high spectral resolution infrared solar absorption spectra recorded between January 1999 and June 2011 ... [more ▼]

The long-term trend of the atmospheric carbon tetrachloride (CCl4) burden has been retrieved from high spectral resolution infrared solar absorption spectra recorded between January 1999 and June 2011. The observations were made with a Fourier transform spectrometer at the northern mid-latitude, high altitude Jungfraujoch station in Switzerland (46.5°N latitude, 8.0°E longitude, 3580 m altitude). Total columns were derived from spectrometric analysis of the strong CCl4 ν3 band at 794 cm-1, accounting for all interfering molecules (e.g., H2O, CO2, O3, and a dozen weakly absorbing gases). A significant improvement in the fitting residuals and in the retrieved CCl4 columns was obtained by taking into account line mixing in a strong interfering CO2 Q branch. This procedure had never been implemented in remote sensing CCl4 retrievals though its importance was noted in earlier studies. A fit to the CCl4 daily mean total column time series returns a statistically-significant long-term trend of (-1.49±0.08 x 1013 molec./cm2)/yr, 2-σ. This corresponds to an annual decrease of (-1.31±0.07) pptv for the mean free tropospheric volume mixing ratio. Furthermore, the total column data set reveals a weak seasonal cycle with a peak-to-peak amplitude of 4.5 %, with minimum and maximum values occurring in mid-February and mid-September, respectively. This small seasonal modulation is attributed primarily to the residual influence of tropopause height changes throughout the year. The negative trend of the CCl4 loading reflects the continued impact of the regulations implemented by the Montreal Protocol and its strengthening amendments and adjustments. Despite this statistically significant decrease, the CCl4 molecule currently remains an important contributor to the atmospheric chlorine budget, and thus deserves further monitoring, to ensure continued compliance with these strengthenings, globally. Our present findings are briefly discussed with respect to recent relevant CCl4 investigations at the ground and from space. [less ▲]

Detailed reference viewed: 56 (7 ULg)
Full Text
Peer Reviewed
See detailDecreased Corticosensitivity in Quiescent Crohn's Disease: An Ex Vivo Study Using Whole Blood Cell Cultures
Franchimont, Denis; Louis, Edouard ULg; Dupont, Pierre et al

in Digestive Diseases & Sciences (1999), 44(6), 1208-15

Corticosensitivity influences the degree and the duration of an inflammatory reaction by altering target cell responses to endogenous and/or exogenous glucocorticoids. Indeed, different clinical responses ... [more ▼]

Corticosensitivity influences the degree and the duration of an inflammatory reaction by altering target cell responses to endogenous and/or exogenous glucocorticoids. Indeed, different clinical responses to glucocorticoids have been observed among patients with Crohn's disease, suggesting different degrees of corticosensitivity in these subjects. The purpose of this study was to compare the corticosensitivity of patients with quiescent Crohn's disease to that of healthy subjects (HS). Nineteen patients with quiescent Crohn's disease and 14 HS were studied; all patients were steroid-free for at least six months; 7 of the 19 were corticosteroid-dependent (CSD) and treated with nonglucocorticoid immunosuppressants at the time of the study. Corticosensitivity was measured by the inhibition of LPS-induced cytokine secretion in whole blood cell cultures treated with increasing concentrations (10(-9) to 10(-6) M) of dexamethasone. Tumor-necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1 beta (IL-1 beta) were measured using specific immunoassays. Crohn's disease patients had a markedly decreased dexamethasone-mediated inhibition of TNF-alpha (P < 0.01), IL-6 (P < 0.001), and IL-1 beta (P < 0.01) compared to healthy subjects, with a shift of the dexamethasone dose-response curve to the right. No significant differences in the basal and LPS-stimulated secretion of the three cytokines were observed between CSD and non-CSD patients, and both subgroups of patients had similar degrees of dexamethasone-mediated cytokine inhibition. We conclude that patients with Crohn's disease have a significant decrease in the corticosensitivity of their leukocytes. This may be related to a specific genetic/constitutional background and/or could be acquired, due to inflammation-related endocrine and/or immune factors. [less ▲]

Detailed reference viewed: 27 (2 ULg)
Peer Reviewed
See detailDecreased Expression of Galectin-3 in Basal Cell Carcinoma of the Skin
Castronovo, Vincenzo ULg; Liu, F. T.; van den Brule, F. A.

in International Journal of Oncology (1999), 15(1), 67-70

Galectins are beta-galactoside-binding lectins that play multiple roles during tumor progression. Previous work conducted in our laboratory has demonstrated decreased galectin-3 expression in carcinomas ... [more ▼]

Galectins are beta-galactoside-binding lectins that play multiple roles during tumor progression. Previous work conducted in our laboratory has demonstrated decreased galectin-3 expression in carcinomas from colon, breast, ovary and endometrium, compared to the corresponding normal tissues. In this study, we examined the pattern of galectin-3 expression by immunohistochemistry in a group of 10 basal cell carcinomas of the skin. In the surrounding normal skin, galectin-3 immunostaining was found predominantly in the middle epidermis (spine layer) and eccrine sweat glands. Compared to the normal epidermal cells, basal carcinoma cells observed in all 10 samples examined presented with significantly decreased galectin-3 immunostaining. These data further demonstrates that galectin-3 is down-regulated in a variety of human cancers, including basal cell carcinoma. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailDecreased expression of galectin-3 is associated with progression of human breast cancer.
Castronovo, Vincenzo ULg; van den Brule, Frédéric; Jackers, Pascale ULg et al

in Journal of Pathology (The) (1996), 179(1), 43-48

Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in several biological events including binding to the basement membrane glycoprotein laminin. Although the exact role of ... [more ▼]

Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in several biological events including binding to the basement membrane glycoprotein laminin. Although the exact role of galectin-3 during the interactions between cells and laminin is not yet known, it has recently been observed that its expression is down-regulated at both the protein and the mRNA level in colon cancer tissues in correlation with progression of the disease. This study investigated the possibility that breast cancer cells might also exhibit decreased galectin-3 expression in association with their aggressiveness. The expression of galectin-3 was examined by immunoperoxidase staining, using a polyclonal antibody raised against recombinant galectin-3, in a collection of 98 human breast lesions including 12 fibroadenomas, 15 fibrocystic disease lesions, 22 in situ carcinomas, and 49 infiltrating ductal carcinomas, 19 of which had positive axillary lymph nodes. Normal breast tissue adjacent to the lesions was present in 59 biopsies. Normal breast tissue expressed high levels (3+) of galectin-3. High expression (2+ to 3+) was also found in most benign lesions examined. The expression of galectin-3 was significantly decreased in in situ carcinoma and this down-regulation was more pronounced in invasive ductal carcinoma, particularly when associated with infiltration of axillary lymph nodes. These data constitute the first observation that galectin-3 is down-regulated in breast cancer and suggest the decreased expression of this galactoside-binding lectin is associated with the acquisition of the invasive and metastatic phenotype. [less ▲]

Detailed reference viewed: 45 (27 ULg)
Full Text
Peer Reviewed
See detailDecreased local control following radiation therapy alone in early larynx cancer with anterior commisure extension
Ozsahin; Bron; COUCKE, Philippe ULg et al

in Radiotherapy & Oncology (2002), 64(supp 1), 243-244

Detailed reference viewed: 4 (0 ULg)