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See detailThe contribution of processing fluency to preference : a comparison with familiarity-based recognition
Willems, Sylvie ULg; Van der Linden, Martial ULg; Bastin, Christine ULg

in European Journal of Cognitive Psychology (2007), 19(1), 119-140

There is a great deal of evidence supporting the idea that, when a stimulus is processed fluently, it is more likely to be judged as pleasant. However, this influence of fluency on preference judgement ... [more ▼]

There is a great deal of evidence supporting the idea that, when a stimulus is processed fluently, it is more likely to be judged as pleasant. However, this influence of fluency on preference judgement seems to depend on several experimental conditions. So we tried to better understand these conditions via a comparison with recognition and by manipulating some aspects of the procedure (test format) and material (similarity and figure-ground contrast of the stimuli). Two experiments showed that some conditions maximally induce the use of processing fluency in a preference judgement, as in a recognition task. We discuss the implications of these findings for the well-documented discrepancy-attribution hypothesis (Whittlesea [less ▲]

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See detailThe contribution of recollection and familiarity to recognition memory : A study of the effects of test format and aging
Bastin, Christine ULg; Van der Linden, Martial ULg

in Neuropsychology (2003), 17(1), 14-24

Whether the format of a recognition memory task influences the contribution of recollection and familiarity to performance is a matter of debate. The authors investigated this issue by comparing the ... [more ▼]

Whether the format of a recognition memory task influences the contribution of recollection and familiarity to performance is a matter of debate. The authors investigated this issue by comparing the performance of 64 young (mean age = 21.7 years; mean education = 14.5 years) and 62 older participants (mean age = 64.4 years; mean education = 14.2 years) on a yes–no and a forced-choice recognition task for unfamiliar faces using the remember– know–guess procedure. Familiarity contributed more to forced-choice than to yes–no performance. Moreover, older participants, who showed a decrease in recollection together with an increase in familiarity, performed better on the forced-choice task than on the yes–no task, whereas younger participants showed the opposite pattern. [less ▲]

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See detailThe contribution of recollection and familiarity to recognition memory performance in chronic pain patients
Grisart, Jacques; Van der Linden, Martial ULg; Bastin, Christine ULg

in Behaviour research and therapy (2007), 45

This study examines the selective impact of chronic pain on memory functioning in a recognition task. Thirty chronic pain patients and 30 healthy control subjects performed a yes–no word recognition test ... [more ▼]

This study examines the selective impact of chronic pain on memory functioning in a recognition task. Thirty chronic pain patients and 30 healthy control subjects performed a yes–no word recognition test. The contribution of recollection and familiarity to both groups’ performance was compared by means of the Remember/Know (R/K) procedure, which distinguishes recognition based on the recollection of the encoding episode (R responses) and recognition accompanied by a feeling of familiarity (K responses). Chronic pain patients showed a decrease in recollection together with an increase in familiarity: indeed, they reported less R and more K responses than control subjects. This pattern of performance was not related to the overall recognition ability. These findings are consistent with the hypothesis of the attentional cost of chronic pain, suggesting a selective impact of chronic pain on the most attention-demanding cognitive processes, such as recollection. This study emphasises the relevance of specific procedures distinguishing the underlying components of memory functioning rather than solely global indicators. [less ▲]

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See detailContribution of reticular nuclei in the pathophysiology of parkinsonian rigidity
Delwaide, Paul ULg; PEPIN, Jean-Louis ULg; MAERTENS DE NOORDHOUT, Alain ULg

in Narabayashi, H.; Nagatsu, T.; yanagisawa, N. (Eds.) et al Advances in Neurology - Vol 60 (1993)

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See detailContribution of Revised International Prognostic Scoring System Cytogenetics to Predict Outcome After Allogeneic Stem Cell Transplantation for Myelodysplastic Syndromes: A Study From the Socie 0 te0 FranO´ aise de Greffe de Moelle et The 0 rapies Cellulaires
Gauthier, Jordan; Damaj, Gandhi; Langlois, Carole et al

in Transplantation (in press)

Background. The prognosis of myelodysplastic syndromes (MDS) after allogeneic stem cell transplantation is critically determined by cytogenetic abnormalities, as previously defined by International ... [more ▼]

Background. The prognosis of myelodysplastic syndromes (MDS) after allogeneic stem cell transplantation is critically determined by cytogenetic abnormalities, as previously defined by International Prognostic Scoring System (IPSS) cytogenetics. It has been shown that a new cytogenetic classification, included in the IPSS-R (cytogenetic-IPSS-R [C-IPSS-R]), can better predict the outcome of untreated MDS patients.Methods. In this study, we assessed the impact of the IPSS-R cytogenetic score (C-IPSS-R) on the outcome of 367 MDS patients transplanted from HLA-identical siblings or HLA allele-matched unrelated donors. Results. According to the C-IPSS-R, 178 patients (48%) fell in the good risk, 102 (28%) in the intermediate risk, 77 (21%) in the poor risk, and 10 (3%) in the very poor risk group. In multivariate analysis, after a median follow-up of 4 years, the poor and very poor-risk categories correlated with shorter overall survival (OS) (4-year OS, 32%; hazard ratio [HR], 1.59; P = 0.009 and OS, 10%; HR, 3.18; P = 0.002, respectively) and higher cumulative incidence of relapse (CIR) (CIR, 52%; HR, 1.82; P = 0.004 and CIR, 60%; HR, 2.44; P = 0.060, respectively). Conclusions. Overall, the C-IPSS-R changed the IPSS cytogenetic risk only in 8% of cases but identified a new risk group, the very poor C-IPSS-R category, with dismal outcome after allogeneic stem cell transplantation (10% 4-year OS, 60% 4-year CIR). Posttransplantation maintenance therapy should be investigated in prospective trials for patients with high-risk C-IPSS-R karyotypes. [less ▲]

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See detailContribution of Robotic Surgery to Gynecologic Oncology
GOFFIN, Frédéric ULg

Conference (2012, September 14)

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See detailContribution of SAR interferometry (from ERS1/2) in the study of aeolian transport processes : The cases of Niger, Mauritania and Morocco
Bodart, Catherine; Gassani, Jean; Salmon, Marc ULg et al

in Marini, Alberto; Talbi, Mohamed (Eds.) Desertification and risk analysis using high and medium resolution satellite data (2009)

In order to face desertification and sand encroachment of inter dunes depressions, as well as to protect soils in the area of Gouré (Southeast Niger) where it is possible to have food plantations, it is ... [more ▼]

In order to face desertification and sand encroachment of inter dunes depressions, as well as to protect soils in the area of Gouré (Southeast Niger) where it is possible to have food plantations, it is essential to localize the origin and drift of sands. This paper shows that radar satellite remote sensing and interferometry offers the opportunity to gather all the required information. Digital Elevation Models (DEM) generated by interferometry on ERS 1-2 SAR images (a tandem pair acquired on April 25 and 26 1996) helped to collect information on relief and provided an aeolian model, while giving some insight into the spatial distribution of sand formations. Interpreting the interferometric coherent image by means of a color composite allowed detecting and locating sand movements in the areas under study. This project mainly highlights the contribution of SAR interferometry in the study of sand movements by developing added-value products. Interpretations were validated using highresolution satellite data (SPOT 5, IKONOS, and QUICKBIRD) and field observations made during a campaign in Niger in March 2004. The same procedure was also applied in Mauritania using two tandem pairs (2–3 November 1995 and 7–8 December 1995) and in Southern Morocco (18–19 May 1996) in order to identify active dunes in these regions. These observations will be taken into account when analyzing ENVISAT-ASAR data. [less ▲]

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See detailContribution of Services of General Interest
Gathon, Henry-Jean ULg; Sluse, Myriam ULg; Anghinelli, Stefania et al

Report (2004)

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See detailThe contribution of short-term memory for serial order to early reading acquisition: Evidence from a longitudinal study
Martinez Perez, Trecy ULg; Majerus, Steve ULg; Poncelet, Martine ULg

in Journal of Experimental Child Psychology (2012), 111

Early reading acquisition skills have been linked to verbal short-term memory (STM) capacity. However, the nature of this relationship remains controversial, since verbal STM, like reading acquisition ... [more ▼]

Early reading acquisition skills have been linked to verbal short-term memory (STM) capacity. However, the nature of this relationship remains controversial, since verbal STM, like reading acquisition, depends upon the complexity of underlying phonological processing skills. This longitudinal study addressed the relation between STM and reading decoding acquisition by distinguishing between STM for item and STM for order information, based on recent studies showing that STM for item information recruits underlying phonological representations, but not STM for order information. If there is a specific link between STM and reading decoding acquisition, STM for order information should be an independent predictor of reading decoding acquisition. Tasks maximizing STM for serial order or item information, measures of phonological abilities and reading tests were administered to children followed from kindergarten through 1st grade. We observed that order STM capacity but not item STM capacity predicted independent variance in reading decoding abilities one year later. These results highlight the specific role of STM for order in reading decoding acquisition, and argue for a causal role of order STM capacity in reading acquisition. Mechanisms relating STM for order information and reading acquisition will be discussed. [less ▲]

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See detailContribution of sleep to memory consolidation
Shaffii-Le Bourdiec, Anahita; Muto, Vincenzo ULg; Mascetti, Laura et al

in Future Neurology (2010), 5(2), 325-338

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See detailThe contribution of social rank and attachment theory to depression in a non clinical sample of adolescents
Puissant, Sylvia Pinna; Gauthier, Jean-Marie ULg; Van Oirbeek, R. KUL

in Spanish Journal of Psychology (The) (2011)

This study explores the relative contribution of the overall quality of attachment to the mother, to the father and to peers (Inventory of Parent and Peer Attachment scales), the style of attachment ... [more ▼]

This study explores the relative contribution of the overall quality of attachment to the mother, to the father and to peers (Inventory of Parent and Peer Attachment scales), the style of attachment towards peers (Attachment Questionnaire for Children scale), the social rank variables (submissive behavior and social comparison), and sex and age variables in predicting the depression score (Center of Epidemiological Studies Depression Scale) on a non-psychiatric sample of 13-18 year old adolescents (n = 225). Results of our integrated model (adjusted R-Square of .50) show that attachment variables (overall quality of attachment to the father and to the mother), social rank variables (social comparison and submissive behavior), age and sex are important in predicting depressive symptoms during adolescence. Moreover, the attachment to peers variables (quality of attachment to peers, secure and ambivalent style of attachment) and sex are mediated by the social rank variables (social comparison and submissive behavior). [less ▲]

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See detailContribution of Spray Droplet Pinning Fragmentation to Canopy Retention
Boukhalfa, Hassina dite Hafida ULg; Massinon, Mathieu ULg; Belhamra, Mohamed et al

in Crop Protection (2014), 56

Drop behaviour during impact affects retention. The increase of adhesion is usually seen as the objective when applying crop protection products, while bouncing and shattering are seen as detrimental to ... [more ▼]

Drop behaviour during impact affects retention. The increase of adhesion is usually seen as the objective when applying crop protection products, while bouncing and shattering are seen as detrimental to spray retention. However, observation of drop impacts on barley (Hordeum vulgare L.) using high speed shadowgraphy shows that bouncing and fragmentation can occur in Cassie-Baxter as well as in Wenzel wetting regimes. In this last regime, a part of the drop may remain stuck on the surface, contributing to retention. Using simultaneous measurements of drop impacts with high speed imaging and of retention with fluorophotometry for spray mixtures on excised barley leaves using a Teejet 11003 nozzle at 0.2 MPa, it is observed that about 50% of the drops that fragmented in the Wenzel state remain on the horizontal leaf. Depending on the spray mixture, these impact outcomes accounted for 28 to 46% of retention, the higher contribution being correlated with bigger VMD (Volume Median Diameter). This contribution is not negligible and should be considered when modelling spray retention processes. [less ▲]

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See detailContribution of supercritical CO2 to the preparation of aliphatic polyesters and materials thereof
Stassin, Fabrice; Jérôme, Robert ULg

in Macromolecular Symposia (2004), 217

This paper is a short review of the most recent achievments of CERM in the synthesis of poly (ε-caprolactone) (PCL) and polylactides (PLA) in supercritical carbon dioxide (sc CO2) In addition to the ... [more ▼]

This paper is a short review of the most recent achievments of CERM in the synthesis of poly (ε-caprolactone) (PCL) and polylactides (PLA) in supercritical carbon dioxide (sc CO2) In addition to the rrtacromolecular engineering of these aliphatic polyesters, nanocomposites and PCL microspheres have been prepared with the assistance of this supercritical fluid. [less ▲]

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See detailContribution of the carbohydrate moiety to conformational stability of the carboxypeptidase Y high pressure study.
Dumoulin, Mireille ULg; Ueno, H.; Hayashi, R. et al

in European Journal of Biochemistry (1999), 262(2), 475-83

The process of pressure-induced denaturation of carboxypeptidase Y and the role of the carbohydrate moiety in its response to pressure and low temperature were investigated by measuring in situ the ... [more ▼]

The process of pressure-induced denaturation of carboxypeptidase Y and the role of the carbohydrate moiety in its response to pressure and low temperature were investigated by measuring in situ the catalytic activity and, the intrinsic and 8-anilino-1-naphthalene sulfonic acid binding fluorescences. Pressure-induced denaturation of carboxypeptidase Y is a process involving at least three transitions. Low pressures (below 150 MPa) induced slight conformational changes characterized by a slight decrease in the center of the spectral mass of intrinsic fluorescence, whereas no changes in 8-anilino-1-naphthalene sulfonic acid binding fluorescence were observed and 80% of the catalytic activity remained. Higher pressure (150-500 MPa) induced further conformational changes, characterized by a large decrease in the center of the spectral mass of intrinsic fluorescence, a large increase in the 8-anilino-1-naphthalene sulfonic acid binding fluorescence and the loss of all catalytic activity. Thus, this intermediate exhibited characteristics of molten globule-like state. A further increase, in pressure (above 550 MPa) induced transition from this first molten globule-like state to a second molten globule-like state. This two-stage denaturation process can be explained by assuming the existence of two independent structural domains in the carboxypeptidase molecule. A similar three-transition process was found for unglycosylated carboxypeptidase Y, but, the first two transitions clearly occurred at lower pressures than those for glycosylated carboxypeptidase Y. These findings indicate that the carbohydrate moiety protects carboxypeptidase Y against pressure-induced denaturation. The origin of the protective effects is discussed based on the known crystallographic structure of CPY. [less ▲]

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See detailContribution of the carbohydrate moiety to conformational stability of the carboxypeptidase Y high pressure study.
Dumoulin, Mireille ULg; Ueno, H.; Hayashi, R. et al

in European Journal of Biochemistry (1999), 262(2), 475-83

The process of pressure-induced denaturation of carboxypeptidase Y and the role of the carbohydrate moiety in its response to pressure and low temperature were investigated by measuring in situ the ... [more ▼]

The process of pressure-induced denaturation of carboxypeptidase Y and the role of the carbohydrate moiety in its response to pressure and low temperature were investigated by measuring in situ the catalytic activity and, the intrinsic and 8-anilino-1-naphthalene sulfonic acid binding fluorescences. Pressure-induced denaturation of carboxypeptidase Y is a process involving at least three transitions. Low pressures (below 150 MPa) induced slight conformational changes characterized by a slight decrease in the center of the spectral mass of intrinsic fluorescence, whereas no changes in 8-anilino-1-naphthalene sulfonic acid binding fluorescence were observed and 80% of the catalytic activity remained. Higher pressure (150-500 MPa) induced further conformational changes, characterized by a large decrease in the center of the spectral mass of intrinsic fluorescence, a large increase in the 8-anilino-1-naphthalene sulfonic acid binding fluorescence and the loss of all catalytic activity. Thus, this intermediate exhibited characteristics of molten globule-like state. A further increase, in pressure (above 550 MPa) induced transition from this first molten globule-like state to a second molten globule-like state. This two-stage denaturation process can be explained by assuming the existence of two independent structural domains in the carboxypeptidase molecule. A similar three-transition process was found for unglycosylated carboxypeptidase Y, but, the first two transitions clearly occurred at lower pressures than those for glycosylated carboxypeptidase Y. These findings indicate that the carbohydrate moiety protects carboxypeptidase Y against pressure-induced denaturation. The origin of the protective effects is discussed based on the known crystallographic structure of CPY. [less ▲]

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See detailContribution Of The Hydrophobicity Gradient Of An Amphipathic Peptide To Its Mode Of Association With Lipids
Perez-Mendez, O.; Vanloo, B.; Decout, A. et al

in European Journal of Biochemistry (1998), 256(3), 570-9

A class of peptides that associate with lipids, known as oblique-orientated peptides, was recently described [Brasseur R., Pillot, T., Lins, L., Vandekerckhove, J. & Rosseneu, M. (1997) Trends Biochem ... [more ▼]

A class of peptides that associate with lipids, known as oblique-orientated peptides, was recently described [Brasseur R., Pillot, T., Lins, L., Vandekerckhove, J. & Rosseneu, M. (1997) Trends Biochem. Sci. 22, 167-171]. Due to an asymmetric distribution of hydrophobic residues along the axis of the alpha-helix, such peptides adopt an oblique orientation which can destabilise membranes or lipid cores. Variants of these oblique peptides, designed to have an homogeneous distribution of hydrophobic and hydrophilic residues along the helical axis, are classified as regular amphipathic peptides. These peptides are expected to lie parallel to the polar/apolar interface with their hydrophobic residues directed towards the apolar and their hydrophilic residues towards the polar phase. An hydrophobic, oblique-orientated peptide was identified at residues 56-68 in the sequence of the lecithin-cholesterol acyltransferase (LCAT), enzyme. This peptide is predicted to penetrate a lipid bilayer at an angle of 40 degrees through its more hydrophobic C-terminal end and thereby induce the destabilisation of a membrane or a lipid core. The LCAT-(56-68) wild-type peptide was synthesised together with the LCAT-(56-68, 0 degrees) variant, in which the hydrophobicity gradient was abolished through residue permutations. In two other variants, designed to keep their oblique orientation, the W61 residue was shifted either towards the more hydrophilic N-terminal at residue 57, or to position 68 at the hydrophobic C-terminal end of the peptide. Peptide-induced vesicle fusion was demonstrated by fluorescence measurements using pyrene-labeled vesicles and by monitoring of vesicle size by gel filtration. The interaction between peptides and lipids was monitored by measurement of the intrinsic tryptophan fluorescence emission of the peptides. Fluorescence polarisation measurements, using diphenyl hexatriene, were carried out to follow changes in the lipid fluidity. The LCAT-(56-68) wild-type peptide and the two oblique variants, induced fusion of unilamellar dimyristoylglycerophosphocholine vesicles. Tryptophan fluorescence emission measurements showed a 12-14 nm blue shift upon addition of the wild-type peptide and of the W61-->68 variant to lipids, whereas the fluorescence of the W61-->57 variant did not change significantly. This observation supports the insertion of the more hydrophobic C-terminal residues into the lipid phase, as predicted by the theoretical calculations. In contrast, the 0 degrees variant peptide had no fusogenic activity, and it associated with lipids to form small discoidal lipid/peptide complexes. The phospholipid transition temperature was decreased after addition of the wild-type, the W61-->68 and W61-->57 fusogenic peptides, whereas the opposite effect was observed with the 0 degrees variant. The behaviour of the wild-type and variant LCAT-(56-68) peptides stresses the contribution of the hydrophobicity gradient along the axis of an amphipathic peptide to the mode of association of this peptide with lipids. This parameter consequently influences the structural modifications occurring to lipids upon association with amphipathic peptides. [less ▲]

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See detailContribution Of The Hydrophobicity Gradient To The Secondary Structure And Activity Of Fusogenic Peptides
Decout, A.; Labeur, C.; Vanloo, B. et al

in Molecular Membrane Biology (1999), 16(3), 237-46

Fusogenic peptides belong to a class of helical amphipathic peptides characterized by a hydrophobicity gradient along the long helical axis. According to the prevailing theory regarding the mechanism of ... [more ▼]

Fusogenic peptides belong to a class of helical amphipathic peptides characterized by a hydrophobicity gradient along the long helical axis. According to the prevailing theory regarding the mechanism of action of fusogenic peptides, this hydrophobicity gradient causes the tilted insertion of the peptides in membranes, thus destabilizing the lipid core and, thereby, enhancing membrane fusion. To assess the role of the hydrophobicity gradient upon the fusogenic activity, two of these fusogenic peptides and several variants were synthesized. The LCAT-(57-70) peptide, which is part of the sequence of the lipolytic enzyme lecithin cholesterol acyltransferase, forms stable beta-sheets in lipids, while the apolipoprotein A-II (53-70) peptide remains predominantly helical in membranes. The variant peptides were designed through amino acid permutations, to be either parallel, perpendicular, or to retain an oblique orientation relative to the lipid-water interface. Peptide-induced vesicle fusion was monitored by lipid-mixing experiments, using fluorescent probes, the extent of peptide-lipid association, the conformation of lipid-associated peptides and their orientation in lipids, were studied by Fourier Transformed Infrared Spectroscopy. A comparison of the properties of the wild-type and variant peptides shows that the hydrophobicity gradient, which determines the orientation of helical peptides in lipids and their fusogenic activity, further influences the secondary structure and lipid binding capacity of these peptides. [less ▲]

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