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Peer Reviewed
See detailCoupling EIA and SEA of large urban infrastructures: the Liege-Guillemins case study
Cremasco, Veronica; Ruelle, Christine ULg; Teller, Jacques ULg

in Proc. of COST C8 final conference, Sustainable Urban Infrastructure, approaches – solutions – networking (2003)

Detailed reference viewed: 46 (5 ULg)
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See detailCoupling GIS with database for hydrogeological mapping.
Bouezmarni, Mohamed ULg

Conference (2003, May)

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See detailCoupling heat and chemical tracer experiments for estimating heat transfer parameters in shallow alluvial aquifers
Wildemeersch, Samuel ULg; Jamin, Pierre ULg; Orban, Philippe ULg et al

in Journal of Contaminant Hydrology (2014), 169

Geothermal energy systems, closed or open, are increasingly considered for heating and/or cooling buildings. The efficiency of such systems depends on the thermal properties of the subsurface. Therefore ... [more ▼]

Geothermal energy systems, closed or open, are increasingly considered for heating and/or cooling buildings. The efficiency of such systems depends on the thermal properties of the subsurface. Therefore, feasibility and impact studies performed prior to their installation should include a field characterization of thermal properties and a heat transfer model using parameter values measured in situ. However, there is a lack of in situ experiments and methodology for performing such a field characterization, especially for open systems. This study presents an in situ experiment designed for estimating heat transfer parameters in shallow alluvial aquifers with focus on the specific heat capacity. This experiment consists in simultaneously injecting hot water and a chemical tracer into the aquifer and monitoring the evolution of groundwater temperature and concentration in the recovery well (and possibly in other piezometers located down gradient). Temperature and concentrations are then used for estimating the specific heat capacity. The first method for estimating this parameter is based on a modeling in series of the chemical tracer and temperature breakthrough curves at the recovery well. The second method is based on an energy balance. The values of specific heat capacity estimated for both methods (2.30 and 2.54 MJ/m3/K) for the experimental site in the alluvial aquifer of the Meuse River (Belgium) are almost identical and consistent with values found in the literature. Temperature breakthrough curves in other piezometers are not required for estimating the specific heat capacity. However, they highlight that heat transfer in the alluvial aquifer of the Meuse River is complex and contrasted with different dominant process depending on the depth leading to significant vertical heat exchange between upper and lower part of the aquifer. Furthermore, these temperature breakthrough curves could be included in the calibration of a complex heat transfer model for estimating the entire set of heat transfer parameters and their spatial distribution by inverse modeling. [less ▲]

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See detailCoupling heat and salt tracer experiment for the estimation of heat transfer and solute transport parameters
Wildemeersch, Samuel ULg; Jamin, Pierre ULg; Orban, Philippe ULg et al

Conference (2013, April 22)

Geothermal energy is a promising source of energy in the context of sustainable development. Therefore, very low enthalpy geothermal systems (open or closed) are increasingly considered for heating or ... [more ▼]

Geothermal energy is a promising source of energy in the context of sustainable development. Therefore, very low enthalpy geothermal systems (open or closed) are increasingly considered for heating or cooling houses and offices using groundwater energy. However, prior to the development of such systems, a feasibility study and an impact study of the system on groundwater ressources are required. Thereliability of such studies is highly dependent on the quality of the estimation of heat transfer parameters. This highlights the necessity of estimating properly such parameters. The objective of this study is to combine the use of heat and salt tracers to estimate simultaneously heat transfer and solute transport parameters in an alluvial aquifer. Additionally, coupling heat and salt tracing experiments is particularly useful for comparing heat transfer and solute transport processes occurring in the subsurface. An experimental field site, located near Liege (Belgium), is equipped with 21 piezometers drilled in the alluvial deposits of the Meuse River. These alluvial deposits are composed of a loess layer (3 m) overlying a sand and gravel layer which constitutes the alluvial aquifer (7 m). The coupled tracing experiment consists in injecting simultaneously heated water and salt in a piezometer and monitoring the evolution of groundwater temperature and salt concentration in a series of control panels set perpendicularly to groundwater flow. This coupled tracing experiment is then simulated using a numerical model. The estimation of heat transfer and solute transport parameters is obtained by calibrating this numerical model using inversion tools. The present study proposes a methodology coupling heat and salt tracing experiment for estimating heat transfer parameters at the field scale. Furthermore, this coupled tracing experiment shows that the comportment of heat and solute in the subsurface presents key differences. [less ▲]

Detailed reference viewed: 57 (23 ULg)
Peer Reviewed
See detailCoupling long term database with SWAT and STICS models for testing modles and simulating nitrogen management scenarios
Deneufbourg, Mathieu ULg; Pugeaux, Nicolas; Huguet, Jean et al

Poster (2012, June 26)

Detailed reference viewed: 28 (4 ULg)
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See detailCoupling of cell migration with neurogenesis by proneural bHLH factors.
Ge, Weihong; He, Fei; Kim, Kevin J. et al

in Proceedings of the National Academy of Sciences of the United States of America (2006), 103(5), 1319-24

After cell birth, almost all neurons in the mammalian central nervous system migrate. It is unclear whether and how cell migration is coupled with neurogenesis. Here we report that proneural basic helix ... [more ▼]

After cell birth, almost all neurons in the mammalian central nervous system migrate. It is unclear whether and how cell migration is coupled with neurogenesis. Here we report that proneural basic helix-loop-helix (bHLH) transcription factors not only initiate neuronal differentiation but also potentiate cell migration. Mechanistically, proneural bHLH factors regulate the expression of genes critically involved in migration, including down-regulation of RhoA small GTPase and up-regulation of doublecortin and p35, which, in turn, modulate the actin and microtubule cytoskeleton assembly and enable newly generated neurons to migrate. In addition, we report that several DNA-binding-deficient proneural genes that fail to initiate neuronal differentiation still activate migration, whereas a different mutation of a proneural gene that causes a failure in initiating cell migration still leads to robust neuronal differentiation. Collectively, these data suggest that transcription programs for neurogenesis and migration are regulated by bHLH factors through partially distinct mechanisms. [less ▲]

Detailed reference viewed: 236 (9 ULg)
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See detailCoupling of hydrogeological models with hydrogeophysical data to characterize seawater intrusion and shallow geothermal systems
Beaujean, Jean ULg; Kemna, Andreas; Engesgaard, Peter et al

Conference (2013, December 12)

While coastal aquifers are being stressed due to climate changes and excessive groundwater withdrawals require characterizing efficiently seawater intrusion (SWI) dynamics, production of geothermal energy ... [more ▼]

While coastal aquifers are being stressed due to climate changes and excessive groundwater withdrawals require characterizing efficiently seawater intrusion (SWI) dynamics, production of geothermal energy is increasingly being used to hinder global warming. To study these issues, we need both robust measuring technologies and reliable predictions based on numerical models. SWI models are currently calibrated using borehole observations. Similarly, geothermal models depend mainly on the temperature field at few locations. Electrical resistivity tomography (ERT) can be used to improve these models given its high sensitivity to TDS and temperature and its relatively high lateral resolution. Inherent geophysical limitations, such as the resolution loss, can affect the overall quality of the ERT images and also prevent the correct recovery of the desired hydrochemical property. We present an uncoupled and coupled hydrogeophysical inversion to calibrate SWI and thermohydrogeologic models using ERT. In the SWI models, we demonstrate with two synthetic benchmarks (homogeneous and heterogeneous coastal aquifers) the ability of cumulative sensitivity-filtered ERT images using surface-only data to recover the hydraulic conductivity. Filtering of ERT-derived data at depth, where resolution is poorer, and the model errors make the dispersivity more difficult to estimate. In the coupled approach, we showed that parameter estimation is significantly improved because regularization bias is replaced by forward modeling only. Our efforts are currently focusing on applying the uncoupled/coupled approaches on a real life case study using field data from the site of Almeria, SE Spain. In the thermohydrogeologic models, the most sensitive hydrologic parameters responsible for heat transport are estimated from surface ERT-derived temperatures and ERT resistance data. A real life geothermal experiment that took place on the Campus De Sterre of Ghent University, Belgium and a synthetic case are tested. They consist in a thermal injection and storage of water in a shallow sandy aquifer. The use of a physically-based constraint accounting for the difference in conductivity between the formation and the tap injected water and based on the hydrogeological model calibrated first on temperatures is necessary to improve the parameter estimation. Results suggest that time-lapse ERT data may be limited but useful information for estimating groundwater flow and transport parameters for both the convection and conduction phases. [less ▲]

Detailed reference viewed: 43 (6 ULg)
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See detailCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel Openers
Gillotin, F.; Chiap, Patrice ULg; Frederich, Michel ULg et al

in Drug Metabolism and Disposition : The Biological Fate of Chemicals (2010), 38(2), 232-240

SUR1-selective ATP-sensitive potassium channel openers (PCOs) have been shown to be of clinical value for the treatment of several metabolic disorders, including type I and type II diabetes, obesity and ... [more ▼]

SUR1-selective ATP-sensitive potassium channel openers (PCOs) have been shown to be of clinical value for the treatment of several metabolic disorders, including type I and type II diabetes, obesity and hyperinsulinemia. Taking into account these promising therapeutic benefits, different series of 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides structurally related to diazoxide were developed. In view of the lead optimisation process of the series, knowledge of ADMET parameters, and more particularly the metabolic fate of these compounds, is a fundamental requirement. For such a purpose, two selected promising compounds (BPDZ 73 and BPDZ 157) were incubated in the presence of phenobarbital-induced rat liver microsomes to produce expected mammal in vivo phase I metabolites. The resulting major metabolites were then analysed by both MS and NMR in order to completely elucidate their chemical structures. The two compounds were also further incubated in the presence of non-treated rats and human microsomes in order to compare the metabolic profiles. In the present study, the combined use of an exact mass LC-MS/MS platform and a LC-SPE-NMR system allowed the clarification of some unresolved structural assessments in the accurate chemical structure elucidation process of the selected PCOs drugs. These results greatly help the optimization of the lead compounds. [less ▲]

Detailed reference viewed: 126 (42 ULg)
See detailCoupling of N Qubits to Any Dicke State via Projective Measurements
Thiel, C.; Maser, A.; Bastin, Thierry ULg et al

Conference (2008)

Detailed reference viewed: 8 (0 ULg)
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See detailCoupling of parallel river and groundwater models to simulate dynamic groundwater boundary conditions
Carabin, Guy; Dassargues, Alain ULg

in Bentley, L. R.; Sykes, J. F.; Brebbia, C. A. (Eds.) et al Proc. of Computational Methods in Water Resources 2000 (2000)

Detailed reference viewed: 18 (2 ULg)
Peer Reviewed
See detailThe coupling of quark and gluon condensates in hot and dense systems
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1994), 567

Detailed reference viewed: 7 (1 ULg)
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See detailCoupling of three lattice instabilities
Ghosez, Philippe ULg; Triscone, Jean-Marc

in Nature Materials (2011), 10

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See detailCoupling of α,ω-dichloropoly (methylphenylsilane) and living poly (styryllithium). Study of the coupling reaction
Demoustier-Champagne, Sophie; Canivet, I.; Devaux, Jacques et al

in Journal of Polymer Science. Part A, Polymer Chemistry (1997), 35(10), 1939-1948

Both di- and triblock copolymers consisting of polystyrene (PS) in conjunction with poly(methylphenylsilane) (PMPS) have been successfully prepared by coupling of ,-dichloro-PMPS with poly(styryllithium ... [more ▼]

Both di- and triblock copolymers consisting of polystyrene (PS) in conjunction with poly(methylphenylsilane) (PMPS) have been successfully prepared by coupling of ,-dichloro-PMPS with poly(styryllithium). The study of this reaction has shown a sudden limitation of the coupling yield, which however depends on the PS block length. Both the polymer concentration and the solvent have also an effect on the coupling reaction. Morphology of the PS-PMPS block copolymers has been observed by transmission electron microscopy. Very complex morphologies have been reported more likely as the result of the competition between the phase separation induced by PS and PMPS immiscibility and the tendency of PMPS to form ordered structures. [less ▲]

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See detailCoupling optimization and dynamic simulation for preventive-corrective control of voltage instability
Capitanescu, Florin ULg; Van Cutsem, Thierry ULg; Wehenkel, Louis ULg

in IEEE Transactions on Power Systems (2009), 24(2), 796-805

This paper proposes an approach coupling security constrained optimal power flow with time-domain simulation to determine an optimal combination of preventive and corrective controls ensuring a voltage ... [more ▼]

This paper proposes an approach coupling security constrained optimal power flow with time-domain simulation to determine an optimal combination of preventive and corrective controls ensuring a voltage stable transition of the system towards a feasible long-term equilibrium, if any of a set of postulated contingencies occurs. A security-constrained optimal power flow is used to adjust the respective contribution of preventive and corrective actions. Furthermore, information is extracted from (quasi steady-state) time-domain simulations to iteratively adjust the set of coupling constraints used by a corrective security constrained optimal power flow until its solution is found dynamically secure and viable. Numerical results are provided on a realistic 55-bus test system. [less ▲]

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See detailCoupling Optiview and Production Simulation
Caprace, Jean-David ULg; Aracil Fernandez, Francisco ULg; Hübler, Michael et al

in Proceeding of the 16th International Conference of Ship and Shipping Research (2009, November)

This paper presents new developments to link OptiView and a Discrete Event production Simulation (DES) software. The OptiView Software, is designed to maximize the number of ship blocks and ship sections ... [more ▼]

This paper presents new developments to link OptiView and a Discrete Event production Simulation (DES) software. The OptiView Software, is designed to maximize the number of ship blocks and ship sections produced in workshops during a certain time window. We decided to combine the strong points of both, the OptiView software and the DES simulation. Indeed, the production simulation is very effective for the modelling of the movement of the gantry crane while OptiView is very powerful for the allocation of blocks and optimization of the surface. This tool was developed to support planners to improve the space utilization and workshop productivity. The combination of both methods will deliver better results for lead time and cost. [less ▲]

Detailed reference viewed: 93 (13 ULg)
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See detailCoupling principal component analysis and Kalman filtering algorithms for on-line aircraft engine diagnostics
Borguet, Sébastien ULg; Léonard, Olivier ULg

in Control Engineering Practice (2009), 17(4), 494-502

Engine health monitoring has been an area of intensive research for more than three decades. Numerous methods have been developed with the goal of performing an accurate assessment of the engine condition ... [more ▼]

Engine health monitoring has been an area of intensive research for more than three decades. Numerous methods have been developed with the goal of performing an accurate assessment of the engine condition. It is generally accepted that a practical implementation of a monitoring tool will rely on a combination of several techniques. In this framework, the present contribution proposes an original approach for coupling two diagnostic tools in order to enhance the capability of an engine health monitoring system. One tool is based on a principal component analysis scheme and the other is based on a Kalman filter technique. The three methodologies are compared and the benefit of the combined tool is demonstrated on simulated fault cases which can be expected in a commercial turbofan layout. (C) 2008 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 47 (7 ULg)