Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
See detailContributions à l’amélioration des systèmes d’évaluations génétiques
Vanderick, Sylvie ULg; Gengler, Nicolas ULg

Conference given outside the academic context (2014)

Detailed reference viewed: 14 (6 ULg)
Full Text
See detailContributions à l'anatomie et à l'histologie des Echinides
Fredericq, Léon ULg

in Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences (1876), LXXXIII

Detailed reference viewed: 7 (1 ULg)
See detailContributions à l’Etude de la Relation Evolutive entre deux Herpèsvirus d’Artiodactyles Africains : l’Herpèsvirus Bovin 4 et l’Herpèsvirus Alcélaphin
Dewals, Benjamin G ULg

Doctoral thesis (2006)

Alcelaphine herpesvirus 1 (AlHV 1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (MCF) when cross species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV 1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (MCF) when cross species transmitted to a variety of susceptible species of the Artiodactyla order. There is no available vaccine against AlHV-1. Several studies suggested that the African buffalo (Syncerus caffer) rather than cattle should be considered as the natural host species of bovine herpesvirus 4 (BoHV 4), an apathogenic gammaherpesvirus that is antigenically related to AlHV 1. Rossiter and co-workers (1989) suggested that an evolutionary relationship exists between AlHV 1 and BoHV 4. This hypothesis proposes that the serological antigenic relationship existing between BoHV 4 and AlHV 1 could confer to BoHV 4 infected buffaloes a protective immune response against lethal AlHV 1 infection. In this work, our goal was to generate information and tools that are required to test this hypothesis in the future. Our results are presented as three original studies: (i) Cloning of the alcelaphine herpesvirus 1 genome as an infectious and pathogenic bacterial artificial chromosome Journal of General Virology (2005), in press Dewals B., Boudry C., Gillet L, Markine-Goriaynoff N., de Leval L., Haig D.M. & Vanderplasschen A. Alcelaphine herpesvirus 1 (AlHV 1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (MCF) when cross species transmitted to a variety of susceptible species of the Artiodactyla order. The study of MCF pathogenesis has been impeded by an inability to produce recombinant viruses, due mainly to the fact that AlHV 1 becomes attenuated during passage in culture. In this study, we have overcome these difficulties by cloning the entire AlHV 1 genome as a stable, infectious and pathogenic bacterial artificial chromosome (BAC). A modified loxP flanked BAC cassette was inserted in one of the two large non-coding regions of the AlHV 1 genome. This insertion allowed the production of an AlHV 1 BAC clone stably maintained in bacteria and able to regenerate virions when transfected into permissive cells. The loxP-flanked BAC cassette was excised from the genome of reconstituted virions by growing them in permissive cells stably expressing Cre recombinase. Importantly, BAC derived AlHV 1 virions replicated comparably to the virulent (low passage) AlHV 1 parental strain and induced MCF in rabbits that was indistinguishable from that of the virulent parental strain. The availability of the AlHV 1 BAC is an important advance for the study of MCF that will allow the identification of viral genes involved in MCF pathogenesis as well as the production of attenuated recombinant candidate vaccines. (ii) Antibodies against bovine herpesvirus 4 are highly prevalent in wild African buffaloes throughout eastern and southern Africa Veterinary Microbiology, 2005, 110, 209-220 Dewals B., Gillet L., Gerdes T., Taracha E.L.N., Thiry E. & Vanderplasschen A. Bovine herpesvirus 4 (BoHV 4) has been isolated from cattle throughout the world. Interestingly, a survey of wild African buffaloes mainly from the Maasai Mara Game Reserve in Kenya revealed that 94 % of the animals tested had anti BoHV 4 antibodies (Rossiter et al., Res. Vet. Sci., 1989, 46, 337 343). These authors also proposed that the serological antigenic relationship existing between BoHV 4 and alcelaphine herpesvirus 1 (AlHV 1) could confer to BoHV 4 infected buffaloes a protective immune response against lethal AlHV 1 infection. In the present study, we addressed two questions related to Rossiter et al. paper. Firstly, to investigate the role of the African buffalo as a natural host species of BoHV 4, the seroprevalence of anti BoHV 4 antibodies was analysed in wild African buffaloes throughout eastern and southern Africa. A total of 400 sera was analysed using two complementary immunofluorescent assays. These analyses revealed that independently of their geographical origin, wild African buffaloes exhibit a seroprevalence of anti BoHV 4 antibodies higher than 68 %. This result is by far above the seroprevalence generally observed in cattle. Our data are discussed in the light of our recent phylogenetic study demonstrating that the BoHV 4 Bo17 gene has been acquired from a recent ancestor of the African buffalo. Secondly, we investigated the humoral antigenic relationship existing between BoHV 4 and AlHV 1. Our results demonstrate that among the antigens expressed in AlHV 1 infected cells, epitope(s) recognized by anti BoHV 4 antibodies are exclusively nuclear, suggesting that the putative property of BoHV 4 to confer an immune protection against AlHV 1 relies on a cellular rather than on a humoral immune response. (iii) Phylogenetic analysis of Bovine herpesvirus 4 strains isolated from cattle and from African buffalo In preparation Dewals B., Thirion M., Markine-Goriaynoff N., Gillet L., de Fays K., Minner F., Daix V., Sharp P.M. & Vanderplasschen A. Bovine herpesvirus 4 (BoHV 4) is a gammaherpesvirus which has been isolated from cattle throughout the world. Virological and serological studies have demonstrated that the African buffalo is also a natural host species of BoHV-4. Interestingly, our phylogenetic study on the BoHV 4 Bo17 gene revealed that this gene has been acquired from an ancestor of the African buffalo around 1.5 million years ago. Study of the Bo17 gene also suggested a relatively ancient transmission of BoHV-4 from the ancestor of the African buffalo to the Bos primigenius lineage, followed by a host-dependent split between zebu and taurine BoHV-4 strains. In the present study, we pursued our investigations on the evolution of BoHV 4. To investigate the phylogenetic relationship existing between BoHV 4 strains isolated from African buffalo in Kenya and from cattle throughout the world, nine strains representative of the BoHV 4 species were compared based on six different regions distributed across the genome. Our phylogenetic analyses led to the following conclusions: (i) BoHV 4 strains from African buffalo and from cattle form clades which have split approximately 700,000 years ago. (ii) Since this divergence, inter clade and intra-clade recombination events occurred at different time in the past. (iii) the topology of the tree formed by zebu and taurine BoHV 4 strains is incompatible with a co-speciation process between BoHV 4 and domestic cattle implying that the latter have been contaminated through recent cross-species transmission. A scenario is proposed to explain how BoHV 4 has been transmitted from African buffalo to cattle and how the virus has reached a world wide distribution in the latter host species. In conclusion, this work generated key information and reagents to test in a near future the hypothesis proposed by Rossiter et al. (1989). The results of this work show the complexity of the interactions existing between viruses and their hosts throughout evolution. [less ▲]

Detailed reference viewed: 54 (20 ULg)
Full Text
See detailContributions à l'étude des Echinides
Fredericq, Léon ULg

in Archives de zoologie expérimentale et générale (1876), V

Detailed reference viewed: 4 (1 ULg)
See detailContributions à l'étude des variations physiologiques de la sécrétion interne du pancréas
Fredericq, Léon ULg

in Archives de Zoologie Expérimentale et Générale (1886)

Detailed reference viewed: 11 (0 ULg)
Full Text
See detailContributions à l’histoire de la vésicule germinative et du premier noyau embryonnaire
Van Beneden, Édouard ULg

in Bulletins de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique (1876), 41(3), 38-85

Detailed reference viewed: 13 (0 ULg)
See detailContributions à la didactique de la statistique
Bair, Jacques ULg; Henry, Valérie ULg

Book published by Editions de l'Université de Liège (2005)

Cet ouvrage contient une série d'articles rédigés par des collègues et des anciens collaborateurs du professeur L. Bragard qui ont tenu à rendre hommage à ce dernier. De nombreux thèmes liés à la ... [more ▼]

Cet ouvrage contient une série d'articles rédigés par des collègues et des anciens collaborateurs du professeur L. Bragard qui ont tenu à rendre hommage à ce dernier. De nombreux thèmes liés à la didactique de la statistique sont abordés. [less ▲]

Detailed reference viewed: 33 (0 ULg)
Full Text
Peer Reviewed
See detailContributions à la fortune de la "Cène" de Léonard de Vinci en France : la copie de Saint-Germain l'Auxerrois à Paris et la copie de Saint-Martin à Saint Martin des Monts
Fagnart, Laure ULg

in Raccolta Vinciana (2005), XXXI

Cet article fournit une analyse détaillée de l’une des copies anciennes de la "Cène" de Léonard de Vinci, celle qui est conservée dans l’église Saint-Germain l’Auxerrois de Paris depuis 1651 au moins. Il ... [more ▼]

Cet article fournit une analyse détaillée de l’une des copies anciennes de la "Cène" de Léonard de Vinci, celle qui est conservée dans l’église Saint-Germain l’Auxerrois de Paris depuis 1651 au moins. Il s’attache à en retracer l’histoire mais aussi à en identifier le commanditaire : la découverte de signatures, soigneusement grattées dans la couche picturale, permet de supposer qu’il s’agit de Jean V Burdelot, issu d’une famille de notaires et de secrétaires du roi mais aussi procureur général du Sénat de Milan. Comme d’autres Français en charge à Milan, Burdelot a pu visiter le réfectoire du couvent Santa Maria delle Grazie et désirer conserver un souvenir de la "Cène", en commandant une copie. Cet article présente également une autre réplique ancienne du chef-d’œuvre de Léonard, jusqu’alors inconnue de la critique, le relief qui est conservé dans l’église de Saint-Martin-des-Monts (La Ferté-Bernard). [less ▲]

Detailed reference viewed: 54 (8 ULg)
Full Text
See detailContributions à la modélisation des incendies dans les bâtiments et de leurs effets sur les structures
Franssen, Jean-Marc ULg

Post doctoral thesis (1997)

Besides the ntroductory and concluding chapter, the body of the thesis is in three parts. The firt part addresses numerical simulation of structural fire behaviour. The second part is dedicated to simple ... [more ▼]

Besides the ntroductory and concluding chapter, the body of the thesis is in three parts. The firt part addresses numerical simulation of structural fire behaviour. The second part is dedicated to simple caluclation methods appropriate for a design office. The this part is dedicated to some aspects of fire safety engineering. In addition, the thesis includes three fire related appendices dedicated to: 1) the evaluation of shear resistance of prestressed concrete beams, 2) the effect of columns failure on the stability of an entire structure, 3) the residual stresses in hot-rolled steel structures sections. [less ▲]

Detailed reference viewed: 256 (13 ULg)
Full Text
See detailContributions aux algorithmes d'intégration temporelle conservant l'énergie en dynamique non-linéaire des structures
Noels, Ludovic ULg

Doctoral thesis (2004)

Les points fondamentaux de mes recherches consistent en une étude mathématique des algorithmes d'intégration temporelle d'une discrétisation de type éléments-finis. Les algorithmes traditionnels d ... [more ▼]

Les points fondamentaux de mes recherches consistent en une étude mathématique des algorithmes d'intégration temporelle d'une discrétisation de type éléments-finis. Les algorithmes traditionnels d'intégration temporelle (Newmark, famille alpha-généralisée, ...) peuvent introduire numériquement de l'énergie dans les systèmes non-linéaires. De nouveaux algorithmes sont dès lors apparus pour permettre d'éviter cette perte de stabilité. Lors de mes études, ces algorithmes ont été étendus, de manière originale, au traitement de la plasticité à l'aide d'un modèle de type hypo-élastique. Ils ont également été étendus au traitement généralisé, dans le cadre tridimensionnel, de l'interaction de contact. Ensuite la mise en oeuvre d'une méthode permettant de combiner, au cours du temps un algorithme implicite stable, avec un algorithme explicite traditionnel a été envisagée. La stabilité du passage d'une méthode explicite vers une méthode implicite a été démontrée par nos soins. Une définition originale de critères automatiques de choix de basculement entre les méthodes a été proposée. Des exemples numériques complexes ont mis en évidences les bonnes performances des algorithmes développés, tant du point de vue de la précision des résultats - confrontés aux résultats expérimentaux si ces derniers existent -, que du point de vue de la réduction des coûts de calcul lorsque la méthode combinée est utilisée. [less ▲]

Detailed reference viewed: 276 (34 ULg)
Full Text
Peer Reviewed
See detailContributions du sommeil a la consolidation mnésique
Maquet, Pierre ULg; Matarazzo; Foret, Ariane ULg et al

in Biologie Aujourd'hui (2010), 204(2), 139-143

Detailed reference viewed: 83 (40 ULg)
Full Text
Peer Reviewed
See detailContributions of a 3D numerical environment for architectural sketches.
Mayeur, A.; Darses, F.; Leclercq, Pierre ULg

in Lecture Notes in Computer Science (2008)

Detailed reference viewed: 28 (4 ULg)
Full Text
Peer Reviewed
See detailContributions of benthic and planktonic primary producers to nitrate and ammonium uptake fluxes in a nutrient-poor shallow coastal area (Corsica, NW Mediterranean)
Lepoint, Gilles ULg; Gobert, Sylvie ULg; Dauby, Patrick ULg et al

in Journal of Experimental Marine Biology and Ecology (2004), 302(1), 107-122

By using the stable isotope N-15, we have measured in situ the uptake of nitrate and ammonium by the seagrass Posidonia oceanica, its leaf epiphyte community, the brown macroalgae Halopteris scoparia and ... [more ▼]

By using the stable isotope N-15, we have measured in situ the uptake of nitrate and ammonium by the seagrass Posidonia oceanica, its leaf epiphyte community, the brown macroalgae Halopteris scoparia and the suspended particulate organic matter (SPOM). In Revellata Bay (Gulf of Calvi, Westem Corsica), which is a very nutrient-poor region, the specific uptake rates (V) (mug N g N 1 h(- 1)) of SPOM measured at ambient concentrations are 10-1000 higher than those of benthic primary producers. Macroalgae have intermediary v, between the seagrass leaf and leaf epiphytes. V are quite variable and the reasons for this variability remain unclear. Despite the difference of specific uptake rates found between benthic and pelagic primary producers, when integrating the uptake fluxes for a water Column of 10 m depth, the contribution of benthic primary producers to N uptake fluxes (g N m(-) (2) h(-) (1)) is significant, corresponding on average to 40% of total uptake flux. This results from the dominance in terms of N biomass of benthic primary producers in this shallow nutrient-poor area. When reported for the entire volume of the Revellata Bay, the contribution of benthic primary producers is reduced to 5 - 10% of total N uptake flux. Although this contribution could appear relatively low, it results in a significant direct transfer of inorganic nitrogen from the water column to the benthic compartment. By this transfer, the benthic plants act as a biological pump incorporating the pelagic N into the benthic compartment for a time longer than the characteristic time of phytoplankton dynamics (month-years vs. day-week). (C) 2003 Elsevier B.V. Alt rights reserved. [less ▲]

Detailed reference viewed: 45 (16 ULg)
Full Text
See detailContributions of collaborative e-annotations in project-based teaching
Leclercq, Pierre ULg; Ben Rajeb, Samia ULg

Scientific conference (2012, December)

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailContributions of experimental mouse models to the understanding of African trypanosomiasis.
Antoine-Moussiaux, Nicolas ULg; Magez, Stefan; Desmecht, Daniel ULg

in Trends in Parasitology (2008), 24(9), 411-8

African trypanosomiasis is the collective name for a wide variety of trypanosome infections that affect humans and livestock. In recent years, experimental mice infection models have provided new insights ... [more ▼]

African trypanosomiasis is the collective name for a wide variety of trypanosome infections that affect humans and livestock. In recent years, experimental mice infection models have provided new insights into both human and animal trypanosomiasis. Mouse models seem to be a valuable and versatile tool in trypanosomiasis-associated pathology and immunology research and highlight the variety shown by African trypanosomiases. Indeed, inbred mouse strains have enabled the study of genetic determinants of susceptibility and of the roles of anti-parasite antibodies, inflammatory mediators and anti-inflammatory mediators for each trypanosome species. Remarkable advances relating to the encephalitic stage of sleeping sickness have also been achieved thanks to murine models. The different contributions of murine models to the African trypanosomiases knowledge are presented here. Future search directions are finally proposed, with respect to mouse model opportunities and limitations. [less ▲]

Detailed reference viewed: 28 (6 ULg)
Full Text
See detailThe contributions of pairs of parallel surfaces in a simple analytical model of room reverberation
Embrechts, Jean-Jacques ULg

in I.C.A. (Ed.) Proceedings of the 2013 ICA Congress (2013, June)

Detailed reference viewed: 44 (15 ULg)